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Pediatric obesity vitamin d

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https://www.readbyqxmd.com/read/29101669/25oh-vitamin-d-levels-in-pediatric-patients-affected-by-prader-willi-syndrome
#1
D Fintini, S Pedicelli, S Bocchini, C Bizzarri, G Grugni, M Cappa, A Crinò
PURPOSE: Obesity, insulin resistance, and puberty seem to influence and been inversely associated with 25-hydroxy vitamin D (25OHD) levels. To our knowledge, a study on 25OHD in children and adolescents with Prader-Willi syndrome (PWS), a genetic form of obesity, is not yet available. OBJECTIVE: To analyze the 25OHD values in pediatric PWS subjects in comparison with a control group (CNT), highlighting the possible correlations with IR, BMD, body composition, pubertal stage, and GH therapy (GHT)...
November 3, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28875607/the-role-of-overweight-and-obesity-on-bone-health-in-korean-adolescents-with-a-focus-on-lean-and-fat-mass
#2
Hwa Young Kim, Hae Woon Jung, Hyunsook Hong, Jae Hyun Kim, Choong Ho Shin, Sei Won Yang, Young Ah Lee
As the associations between pediatric overweight/obesity and bone health remain controversial, we investigated the effects of overweight/obesity as well as lean mass (LM) and fat mass (FM) on bone parameters in adolescents. Bone parameters were evaluated using dual-energy X-ray absorptiometry (DXA) data of 982 adolescents (aged 12-19 years) from the Korea National Health and Nutrition Examination Survey (2009-2010). Z-scores for LM, FM, bone mass, bone mineral density (BMD), and bone mineral apparent density (BMAD) using Korean pediatric reference values were used for analysis...
October 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28843454/pediatric-multiple-sclerosis-genes-environment-and-a-comprehensive-therapeutic-approach
#3
REVIEW
Ryan Cappa, Liana Theroux, J Nicholas Brenton
BACKGROUND: Pediatric multiple sclerosis is an increasingly recognized and studied disorder that accounts for 3% to 10% of all patients with multiple sclerosis. The risk for pediatric multiple sclerosis is thought to reflect a complex interplay between environmental and genetic risk factors. MAIN FINDINGS: Environmental exposures, including sunlight (ultraviolet radiation, vitamin D levels), infections (Epstein-Barr virus), passive smoking, and obesity, have been identified as potential risk factors in youth...
October 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28452835/vitamin-d-status-cardiometabolic-liver-and-mental-health-status-in-obese-youth-attending-a-pediatric-weight-management-center
#4
Krista MacDonald, Kristine Godziuk, Jason Yap, Rena LaFrance, Mohammad Ansarian, Andrea Haqq, Diana R Mager
BACKGROUND: Vitamin D (VitD) deficiency and obesity are reaching epidemic proportions in North America, particularly in those with comorbid conditions such as diabetes or liver disease. The study objective was to determine the prevalence of suboptimal vitD status and interrelationships with anthropometric, cardiometabolic, liver, mental health, and lifestyle (sleep/screen time) parameters in an ambulatory population of children with obesity. METHODS: Children (2-18 years) attending a pediatric weight management clinic (n = 217) were retrospectively reviewed...
October 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28318178/vitamin-d-deficiency-and-insulin-resistance-as-risk-factors-for-dyslipidemia-in-obese-children
#5
Meltem Erol, Özlem Bostan Gayret, Şahin Hamilçıkan, Emrah Can, Özgu L Yiğit
INTRODUCTION: Dyslipidemia is one of the major complications of obesity; vitamin D deficiency and insulin resistance are attending metabolic complications in dyslipidemic obese children. Objective. To determine if vitamin D deficiency and insulin resistance are risk factors for dyslipidemia in obese children. MATERIALS AND METHODS: This study was conducted in the Department of Pediatrics at Bagcilar Training and Research Hospital in Istanbul, Turkey between 2014 and 2015...
April 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28229097/pediatric-hypovitaminosis-d-molecular-perspectives-and-clinical-implications
#6
Rafiu Ariganjoye
Vitamin D, a secosteroid, is essential for the development and maintenance of healthy bone in both the adult and pediatric populations. Low level of 25-hydroxy vitamin D (25-(OH)-D) is highly prevalent in children worldwide and has been linked to various adverse health outcomes including rickets, osteomalacia, osteomalacic myopathy, sarcopenia, and weakness, growth retardation, hypocalcemia, seizure and tetany, autism, cardiovascular diseases, diabetes mellitus, cancers (prostate, colon, breast), infectious diseases (viral, tuberculosis), and autoimmune diseases, such as multiple sclerosis and Hashimoto's thyroiditis...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28221266/body-mass-index-and-the-association-with-vaso-occlusive-crises-in-pediatric-sickle-cell-disease
#7
Andrea Zivot, Nataly Apollonsky, Edward Gracely, Deepti Raybagkar
BACKGROUND: Children with sickle cell disease (SCD) historically have been underweight and have poor overall growth. Recent studies have demonstrated a trend toward obesity in pediatric SCD populations. MATERIALS AND METHODS: Through retrospective chart review of patients with SCD followed at our center, we collected patient's data, including body mass index (BMI), weight percentiles, sickle cell genotype, baseline hemoglobin, medical and psychiatric comorbidities, 25-hydroxy vitamin D level, treatment with hydroxyurea, and chronic transfusions...
May 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28192499/vitamin-d-status-in-pediatric-irritable-bowel-syndrome
#8
Benjamin Udoka Nwosu, Louise Maranda, Ninfa Candela
IMPORTANCE: Irritable bowel syndrome (IBS) is associated with significant morbidity in children and adolescents, and the therapeutic efficacy of available treatment options is limited. The role of vitamin D supplementation in pediatric IBS is unclear as the vitamin D status of pediatric patients with IBS is unknown. Equally, the relationship of vitamin D status with psychosomatic symptoms in children and adolescents is unclear. AIM: To characterize the vitamin D status of pediatric patients with IBS using a case-control study design...
2017: PloS One
https://www.readbyqxmd.com/read/27968929/nutrition-and-skin-kids-are-not-just-little-people
#9
REVIEW
Meagen McCusker, Robert Sidbury
There has been a surge of new data regarding the pathophysiology of skin diseases. We are appreciating the sophisticated interplay among the skin, the immune system, and the environment. More elegant and highly specific medicines have been designed to target certain immune mediators of the adaptive immune system. In parallel fashion, we are learning more about the elegance of the innate immune system and how nutrition as early as the prenatal period can affect the priming of other immune cells. Concerns about the long-term impact of new immune-modulating medicines-especially in the pediatric population-have patients asking their dermatologists for nutritional alternatives to medical therapies...
November 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27671543/no-impact-of-disease-and-its-treatment-on-bone-mineral-density-in-survivors-of-childhood-acute-lymphoblastic-leukemia
#10
COMPARATIVE STUDY
Silky Jain, Sandeep Jain, Gauri Kapoor, Anju Virmani, Ram Bajpai
BACKGROUND: Acute lymphoblastic leukemia (ALL) and its treatment are often implicated in adversely affecting bone health. Conflicting reports in the literature and a paucity of studies from the developing world prompted us to study bone mineral density (BMD) in childhood ALL survivors. METHODS: BMD lumbar spine (LS) and whole body (WB) were evaluated, using dual energy x-ray absorptiometry in 65 pediatric ALL survivors who had been off-therapy for at least 2 years...
April 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27547235/assessment-of-vitamin-d-status-in-a-group-of-egyptian-children-with-non-alcoholic-fatty-liver-disease-multicenter-study
#11
Amal Mohamed Ahmed, Maha Abdel Ghany, Gehan Lotfy Abdel Hakeem, Aya Kamal, Rania Khattab, Asmaa Abdalla, Laila El Morsi Abou El Fotoh, Abdel Azeem El Mazary, Madiha Abdalla Sayed, Ashraf Mohamed Abdel Fadil
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is one of the health problems with great burden on the liver that may end with liver cirrhosis and hepatocellular carcinoma. The aim of this work was to assess serum vitamin D level in nonalcoholic fatty liver disease children. METHODS: This cross sectional case control study involved 47 patients with nonalcoholic fatty liver disease selected while recruiting the pediatric hepatology clinics. Their ages ranged from 5-15 years and were compared with 23 healthy age and sex matched children...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27374182/juvenile-psoriasis-an-epidemiological-study-of-69-cases-in-the-universitary-dermatology-clinic-in-turin
#12
Veronica Arese, Paola Albini, Federica Ibba, Michele Panzone, Ornella Cervetti
BACKGROUND: Psoriasis is a common inflammatory skin disease that affects people of every age; prevalence in pediatric population is unknown because of the lack of studies. METHODS: We collected data about patients 0-18 years old coming to our centre in the period from November 2010 to September 2012. RESULTS: We found 69 children (38 males, 31 females) affected by psoriasis, with a M/F ratio of 1,2 and a prevalence of 0.75%. Plaque psoriasis was the most common clinical manifestation (72,54%), followed by guttate psoriasis (13%)...
June 30, 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27363237/vitamin-d-in-health-and-disease-in-adolescents-when-to-screen-whom-to-treat-and-how-to-treat
#13
REVIEW
Neville H Golden, Dennis E Carey
The existing guidelines on screening and treatment are confusing because different guidelines target different populations. The IOM and AAP guidelines target generally healthy populations, whereas the Endocrine Society and other subspecialty guidelines target individuals with specific medical conditions associated with increased bone fragility. These distinctions have not always been well articulated. For healthy adolescents, the AAP does not recommend universal screening or screening of obese or dark-skinned individuals...
2016: Adolescent Medicine: State of the Art Reviews
https://www.readbyqxmd.com/read/27318855/dietary-intake-and-childhood-leukemia-the-diet-and-acute-lymphoblastic-leukemia-treatment-dallt-cohort-study
#14
MULTICENTER STUDY
Elena J Ladas, Manuela Orjuela, Kristen Stevenson, Peter D Cole, Meiko Lin, Uma H Athale, Luis A Clavell, Jean-Marie Leclerc, Bruno Michon, Marshall A Schorin, Jennifer Greene Welch, Barbara L Asselin, Stephen E Sallan, Lewis B Silverman, Kara M Kelly
OBJECTIVE: Children with acute lymphoblastic leukemia (ALL) are at elevated risk for nutrition-related morbidity both during and after therapy. We present the demographic characteristics and nutrient intake at study entry of a prospective cohort in which evaluating dietary intake in children diagnosed with ALL was investigated. METHODS: Dietary intake data were collected for participants enrolled on the Dana-Farber Cancer Institute ALL Consortium Protocol. Dietary intake was assessed with a food frequency questionnaire and was compared with the dietary reference intake by ALL risk group (standard and high risk)...
October 2016: Nutrition
https://www.readbyqxmd.com/read/27273785/vitamin-d-and-pulmonary-function-in-obese-asthmatic-children
#15
Laura A Lautenbacher, Sunit P Jariwala, Morri E Markowitz, Deepa Rastogi
OBJECTIVE: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. METHODS: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital...
December 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27193136/an-evidence-based-resource-for-the-management-of-comorbidities-associated-with-childhood-overweight-and-obesity
#16
REVIEW
Nicole Thompson, Bobbe Mansfield, Meredith Stringer, Brandy Stewart, Jami Potter, Karen Fernengel
PURPOSE: Overweight and obesity in children and adolescents is often accompanied by obesity-related comorbidities. An integrative review of the literature was performed to create a comprehensive algorithm to help primary care providers manage the common comorbidities associated with childhood overweight and obesity. DATA SOURCES: The Cumulative Index to Nursing and Allied Health Literature, ProQuest Nursing and Allied Health Source, and PubMed databases were searched...
October 2016: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/26684311/pediatric-specific-reference-intervals-in-a-nationally-representative-sample-of-iranian-children-and-adolescents-the-caspian-iii-study
#17
Roya Kelishadi, Hamid Reza Marateb, Marjan Mansourian, Gelayol Ardalan, Ramin Heshmat, Khosrow Adeli
BACKGROUND: This study aimed to determine for the first time the age- and gender-specific reference intervals for biomarkers of bone, metabolism, nutrition, and obesity in a nationally representative sample of the Iranian children and adolescents. METHODS: We assessed the data of blood samples obtained from healthy Iranian children and adolescents, aged 7 to 19 years. The reference intervals of glucose, lipid profile, liver enzymes, zinc, copper, chromium, magnesium, and 25-hydroxy vitamin D [25(OH)D] were determined according to the Clinical & Laboratory Standards Institute C28-A3 guidelines...
August 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/26680652/body-composition-of-patients-with-duchenne-muscular-dystrophy-the-greek-experience
#18
Artemis E Doulgeraki, Helen I Athanasopoulou, Marina S Katsalouli, Glykeria M Petrocheilou, Ioanna N Paspati, Ioannis K Monopolis
Greece ranks among the first countries suffering from the obesity epidemic globally. The aim of the study was to evaluate body composition in Greek patients with Duchenne muscular dystrophy (DMD). We hypothesized that able-bodied patients would not differ from controls, in terms of adiposity, based on clinical observations during everyday practice. STUDY DESIGN: Cross-sectional study of steroid-dependent DMD subjects, who underwent dual-energy X-ray absorptiometry and laboratory metabolic bone profile evaluation...
December 2016: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/26317560/bioavailable-vitamin-d-in-obese-children-the-role-of-insulin-resistance
#19
Emanuele Miraglia del Giudice, Anna Grandone, Grazia Cirillo, Carlo Capristo, Pierluigi Marzuillo, Anna Di Sessa, Giuseppina Rosaria Umano, Laura Ruggiero, Laura Perrone
CONTEXT: Studies examining vitamin D levels in association with childhood obesity usually do not consider the effect of insulin on vitamin D-binding protein and do not calculate the unbound, bioavailable vitamin D. OBJECTIVE: This study aimed to evaluate in a group of children 1) the concentrations of both total 25-hydroxyvitamin D and bioavailable fraction, and 2) the potential role of insulin resistance in modulating the concentrations of bioavailable vitamin D...
October 2015: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/26186300/adiposity-and-cardiometabolic-risk-in-children-with-and-without-antipsychotic-drug-treatment
#20
Ginger E Nicol, Lisa de Las Fuentes, Amy E Riek, Carlos Bernal-Mizrachi, Eric J Lenze, J Phillip Miller, Julia A Schweiger, Michael D Yingling, Vincent J Huang, David J Dixon, Charles H Hennekens, John W Newcomer
CONTEXT: Pediatric obesity is common, particularly in children treated with antipsychotic medications. Antipsychotic exposure can increase cardiometabolic risk by increasing adiposity, and possibly via other adiposity-independent pathways. OBJECTIVE: The objectives were to characterize relationships of adiposity with intrahepatic triglyceride (IHTG) content and carotid intima media thickness (CIMT) in children with and without antipsychotic drug treatment, and to explore whether vitamin D alters any effects in these relationships...
September 2015: Journal of Clinical Endocrinology and Metabolism
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