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https://www.readbyqxmd.com/read/28758425/new-triterpenoid-saponins-from-the-steaming-treated-roots-of-panax-notoginseng
#1
Cheng-Zhen Gu, Yi-Jun Qiao, Dong Wang, Hong-Tao Zhu, Chong-Ren Yang, Min Xu, Ying-Jun Zhang
Further phytochemical investigation of the steaming treated roots of Panax notoginseng (Araliaceae) led to the identification of two new dammarane-type triterpenoid saponins, notoginsenoside SP20 (1) and SP21 (2). In addition, a pair of new phenolic glycosides (3a and 3b) was also isolated together with two known compounds. Their structures were elucidated by HRESIMS, 1D- and 2D-NMR spectra. Compounds 1 and 2 showed no in vitro cytotoxicity against five human cancer cell lines (HL-60, SMMC-7712, A-549, MCF-9 and SW480)...
July 31, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28702081/limitation-of-cellulose-accessibility-and-unproductive-binding-of-cellulases-by-pretreated-sugarcane-bagasse-lignin
#2
Germano Siqueira, Valdeir Arantes, Jack N Saddler, André Ferraz, Adriane M F Milagres
BACKGROUND: The effectiveness of the enzymatic hydrolysis of cellulose in plant cell wall is strongly influenced by the access of enzymes to cellulose, which is at least in part limited by the presence of lignin. Although physicochemical treatments preceding the enzymatic catalysis significantly overcome this recalcitrance, the residual lignin can still play a role in the process. Lignin is suggested to act as a barrier, hindering cellulose and limiting the access of the enzymes. It can also unspecifically bind cellulases, reducing the amount of enzymes available to act on cellulose...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28701863/inhibition-of-hypoxia-induced-cyclooxygenase-2-by-korean-red-ginseng-is-dependent-on-peroxisome-proliferator-activated-receptor%C3%A2-gamma
#3
Heewon Song, Young Joo Lee
BACKGROUND: Korean Red Ginseng (KRG) is a traditional herbal medicine made by steaming and drying fresh ginseng. It strengthens the endocrine and immune systems to ameliorate various inflammatory responses. The cyclooxygenase-2 (COX-2)/prostaglandin E2 pathway has important implications for inflammation responses and tumorigenesis. Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor that regulates not only adipogenesis and lipid homeostasis, but also angiogenesis and inflammatory responses...
July 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28665981/ha117-endows-hl60-cells-with-a-stem-like-signature-by-inhibiting-the-degradation-of-dnmt1-via-its-ability-to-down-regulate-expression-of-the-ggl-domain-of-rgs6
#4
Shuangshuang Li, Xianqing Jin, Huan Wu, Yi Wang, Xiaoqing Li, Yuxia Guo, Shaoyan Liang
All-trans retinoic acid (ATRA) induces complete remission in almost all patients with acute promyelocytic leukemia (APL) via its ability to induce the in vivo differentiation of APL blasts. However, prolonged ATRA treatment can result in drug resistance. In previous studies, we generated a multi-drug-resistant HL60/ATRA cell line and found it to contain a new drug resistance-related gene segment, HA117. In this study, we demonstrate that ATRA induces multi-drug-resistant subpopulations of HL60 cells with a putative stem-like signature by up-regulating the expression of the new gene segment HA117...
2017: PloS One
https://www.readbyqxmd.com/read/28611790/saccharification-performances-of-miscanthus-at-the-pilot-and-miniaturized-assay-scales-genotype-and-year-variabilities-according-to-the-biomass-composition
#5
Nassim Belmokhtar, Stéphanie Arnoult, Brigitte Chabbert, Jean-Paul Charpentier, Maryse Brancourt-Hulmel
HIGHLIGHTS Biomass production and cell wall composition are differentially impacted by harvesting year and genotypes, influencing then cellulose conversion in miniaturized assay.Using a high-throughput miniaturized and semi-automated method for performing the pretreatment and saccharification steps at laboratory scale allows for the assessment of these factors on the biomass potential for producing bioethanol before moving to the industrial scale. The large genetic diversity of the perennial grass miscanthus makes it suitable for producing cellulosic ethanol in biorefineries...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28552597/vasodilation-effect-of-volatile-oil-from-allium-macrostemon-bunge-are-mediated-by-pka-no-pathway-and-its-constituent-dimethyl-disulfide-in-isolated-rat-pulmonary-arterials
#6
Chenghua Han, Jing Qi, Sainan Gao, Chunxiang Li, Ying Ma, Jing Wang, Yuhua Bai, Xiaodong Zheng
The present study aimed to investigate the vasodilation effects of Allium macrostemon Bunge (AMB) on isolated rat pulmonary arterials (PAs) and to assess the underling mechanisms. The volatile oil was extracted by steam distillation from the bulbs of AMB. Then the volatile oil from AMB was studied on isolated rat PA, removal of endothelium, or pretreatment with nitro oxide (NO) synthase (NOS) inhibitor NG-nitro-L-arginine methyl ester (L-NAME), or with protein kinase A (PKA) inhibitor PKI but not cyclooxygenase inhibitor indomethacin significantly blocked the AMB induced relaxation on PE-contracted PA rings...
July 2017: Fitoterapia
https://www.readbyqxmd.com/read/28527765/lignocellulosic-sugar-management-for-xylitol-and-ethanol-fermentation-with-multiple-cell-recycling-by-kluyveromyces-marxianus-iipe453
#7
Diptarka Dasgupta, Debashish Ghosh, Sheetal Bandhu, Dilip K Adhikari
Optimum utilization of fermentable sugars from lignocellulosic biomass to deliver multiple products under biorefinery concept has been reported in this work. Alcohol fermentation has been carried out with multiple cell recycling of Kluyveromyces marxianus IIPE453. The yeast utilized xylose-rich fraction from acid and steam treated biomass for cell generation and xylitol production with an average yield of 0.315±0.01g/g while the entire glucose rich saccharified fraction had been fermented to ethanol with high productivity of 0...
July 2017: Microbiological Research
https://www.readbyqxmd.com/read/28523905/highly-conductive-porous-transition-metal-dichalcogenides-via-water-steam-etching-for-high-performance-lithium-sulfur-batteries
#8
Zhubing Xiao, Zhi Yang, Liujiang Zhou, Linjie Zhang, Ruihu Wang
Lithium-sulfur (Li-S) batteries show significant advantages for next-generation energy storage systems owing to their high energy density and cost effectiveness. The main challenge in the development of long-life and high-performance Li-S batteries is to simultaneously facilitate the redox kinetics of sulfur species and suppress the shuttle effect of polysulfides. In this contribution, we present a general and green water-steam-etched approach for the fabrication of H- and O-incorporated porous TiS2 (HOPT)...
June 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28511543/sterilization-hydration-dehydration-and-tube-fabrication-of-zwitterionic-hydrogels
#9
Xia Han, Hsiang-Chieh Hung, Priyesh Jain, Fang Sun, Xuewei Xu, Wei Yang, Tao Bai, Shaoyi Jiang
Terminal sterilization of hydrogel-based biomaterials is crucial for their clinically relevant applications. The authors synthesized nonfouling zwitterionic hydrogels consisting of carboxybetaine (CB) acrylamide monomer and a carboxybetaine dimethacrylate crosslinker. The mechanical and biological stability of nonfouling hydrogels were investigated using three main terminal sterilization techniques, i.e., steam autoclave, ethylene oxide gas, and gamma irradiation. It was found that CB hydrogels are very stable at high temperature and pressure and in oxidative gas environments without changing their stress, modulus, and nonfouling properties...
May 16, 2017: Biointerphases
https://www.readbyqxmd.com/read/28508770/romuald-w%C3%A4-g%C3%A5-owski-1876-1935-orthopaedic-surgeon-forgotten-pioneer-of-limb-saving-tumour-surgery
#10
Marek Durakiewicz, Mirosław Jabłoński, Aneta Zarębska
On May 16, 1914, The Lancet Journal published a paper by Romuald Węgłowski, a Polish-born professor of Moscow University, entitled "Malignant tumours of bones: a new method in conservative operative treatment." The idea of biological resection presented in the paper consisted in thermocoagulation of the apparently cancerous part of a bone with a jet of steam. According to the author, dead bone rid of live malignant cells reconstructed itself quickly, which helped to preserve the functionality of the organ without considerable limitations...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28500891/steam-exploded-biomass-saccharification-is-predominately-affected-by-lignocellulose-porosity-and-largely-enhanced-by-tween-80-in-miscanthus
#11
Dan Sun, Aftab Alam, Yuanyuan Tu, Shiguang Zhou, Yanting Wang, Tao Xia, Jiangfeng Huang, Ying Li, Zahoor, Xiaoyang Wei, Bo Hao, Liangcai Peng
In this study, total ten Miscanthus accessions exhibited diverse cell wall compositions, leading to largely varied hexoses yields at 17%-40% (% cellulose) released from direct enzymatic hydrolysis of steam-exploded (SE) residues. Further supplied with 2% Tween-80 into the enzymatic digestion, the Mis7 accession showed the higher hexose yield by 14.8-fold than that of raw material, whereas the Mis10 had the highest hexoses yield at 77% among ten Miscanthus accessions. Significantly, this study identified four wall polymer features that negatively affect biomass saccharification as p<0...
September 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28498852/ultra-high-field-7tesla-magnetic-resonance-spectroscopy-in-amyotrophic-lateral-sclerosis
#12
Nazem Atassi, Maosheng Xu, Christina Triantafyllou, Boris Keil, Robert Lawson, Paul Cernasov, Elena Ratti, Christopher J Long, Sabrina Paganoni, Alyssa Murphy, Nouha Salibi, Ravi Seethamraju, Bruce Rosen, Eva-Maria Ratai
The main objective of this study was to utilize high field (7T) in vivo proton magnetic resonance imaging to increase the ability to detect metabolite changes in people with ALS, specifically, to quantify levels of glutamine and glutamine separately. The second objective of this study was to correlate metabolic markers with clinical outcomes of disease progression. 13 ALS participants and 12 age-matched healthy controls (HC) underwent 7 Tesla MRI and MRS. Single voxel MR spectra were acquired from the left precentral gyrus using a very short echo time (TE = 5 ms) STEAM sequence...
2017: PloS One
https://www.readbyqxmd.com/read/28490089/molecular-structure-stability-and-cytotoxicity-of-natural-green-colorants-produced-from-centella-asiatica-l-leaves-treated-by-steaming-and-metal-complexations
#13
Luxsika Ngamwonglumlert, Sakamon Devahastin, Naphaporn Chiewchan
Stability of extracts from Centella asiatica L. leaves treated by steaming and metal-chlorophylls complexations against combined acid-heat was compared with that from untreated leaves and synthetic colorant. Formation of metal-chlorophylls complexes was confirmed by FTIR spectroscopy. Molecular structure changes during stability test and cytotoxicity of the extracts against Vero cells were evaluated. Utilization of the extracts as colorant was also assessed in selected beverage ingredient and food. Copper-chlorophylls extracts exhibited similar green hue to those from untreated and steamed leaves, while zinc-chlorophylls extracts exhibited yellow-green color...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28462130/water-extract-of-galla-rhois-with-steaming-process-enhances-apoptotic-cell-death-in-human-colon-cancer-cells
#14
Nam-Hui Yim, Min Jung Gu, Youn-Hwan Hwang, Won-Kyung Cho, Jin Yeul Ma
BACKGROUND: Galla Rhois has been considered to have medicinal properties against diarrhea, excessive sweating, bleeding, and chronic cough in Asian countries. Gallotannins, which are Galla Rhois-derived tannins, have been reported to possess biological and pharmacological activities, especially anticancer activity. In this study, we evaluated the effect of steaming at a temperature over 120 °C on the chemical constituents and biological activities of the water extract of Galla Rhois (GRE)...
December 2016: Integrative medicine research
https://www.readbyqxmd.com/read/28423891/effective-thermal-inactivation-of-the-spores-of-bacillus-cereus-biofilms-using-microwave
#15
Hyong Seok Park, Jungwoo Yang, Hee Jung Choi, Kyoung Heon Kim
Microwave sterilization was performed to inactivate the spores of biofilms of Bacillus cereus involved in foodborne illness. The sterilization conditions, such as the amount of water and the operating temperature and treatment time, were optimized using statistical analysis based on 15 runs of experimental results designed by the Box-Behnken method. Statistical analysis showed that the optimal conditions for the inactivation of B. cereus biofilms were 14 ml of water, 108°C of temperature, and 15 min of treatment time...
July 28, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28416967/rescuing-ethanol-photosynthetic-production-of-cyanobacteria-in-non-sterilized-outdoor-cultivations-with-a-bicarbonate-based-ph-rising-strategy
#16
Zhi Zhu, Guodong Luan, Xiaoming Tan, Haocui Zhang, Xuefeng Lu
BACKGROUND: Ethanol photosynthetic production based on cyanobacteria cell factories utilizing CO2 and solar energy provides an attractive solution for sustainable production of green fuels. However, the scaling up processes of cyanobacteria cell factories were usually threatened or even devastated by biocontaminations, which restricted biomass or products accumulations of cyanobacteria cells. Thus it is of great significance to develop reliable biocontamination-controlling strategies for promoting ethanol photosynthetic production in large scales...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28413314/implications-of-red-panax-ginseng-in-oxidative-stress-associated-chronic-diseases
#17
REVIEW
Yoon-Mi Lee, Haelim Yoon, Hyun-Min Park, Byeng Chun Song, Kyung-Jin Yeum
The steaming process of Panax ginseng has been reported to increase its major known bioactive components, ginsenosides, and, therefore, its biological properties as compared to regular Panax ginseng. Biological functions of red Panax ginseng attenuating pro-oxidant environments associated with chronic diseases are of particular interest, since oxidative stress can be a key contributor to the pathogenesis of chronic diseases. Additionally, proper utilization of various biomarkers for evaluating antioxidant activities in natural products, such as ginseng, can also be important to providing validity to their activities...
April 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28380543/effect-of-pelleting-on-survival-of-porcine-epidemic-diarrhea-virus-contaminated-feed
#18
R A Cochrane, L L Schumacher, S S Dritz, J C Woodworth, A R Huss, C R Stark, J M DeRouchey, M D Tokach, R D Goodband, J Bia, Q Chen, J Zhang, P C Gauger, R J Derscheid, D R Magstadt, R G Main, C K Jones
Porcine epidemic diarrhea virus (PEDV) is a heat-sensitive virus that has devastated the U.S. swine industry. Because of its heat sensitivity, we hypothesized that a steam conditioner and pellet mill mimicking traditional commercial thermal processing may mitigate PEDV infectivity. Pelleting, a common feed processing method, includes the use of steam and shear forces, resulting in increased temperature of the processed feed. Two thermal processing experiments were designed to determine if different pellet mill conditioner retention times and temperatures would impact PEDV quantity and infectivity by analysis of quantitative reverse transcription PCR and bioassay...
March 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28365338/on-a-clean-power-generation-system-with-the-co-gasification-of-biomass-and-coal-in-a-quadruple-fluidized-bed-gasifier
#19
Linbo Yan, Boshu He
A clean power generation system was built based on the steam co-gasification of biomass and coal in a quadruple fluidized bed gasifier. The chemical looping with oxygen uncoupling technology was used to supply oxygen for the calciner. The solid oxide fuel cell and the steam turbine were combined to generate power. The calcium looping and mineral carbonation were used for CO2 capture and sequestration. The aim of this work was to study the characteristics of this system. The effects of key operation parameters on the system total energy efficiency (ŋten), total exergy efficiency (ŋtex) and carbon sequestration rate (Rcs) were detected...
July 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28355552/energy-transfer-mechanisms-during-molecular-delivery-to-cells-by-laser-activated-carbon-nanoparticles
#20
Aritra Sengupta, Michael D Gray, Sean C Kelly, Stefany Y Holguin, Naresh N Thadhani, Mark R Prausnitz
Previous studies have shown that exposure of carbon black nanoparticles to nanosecond pulsed near-infrared laser causes intracellular delivery of molecules through hypothesized transient breaks in the cell membrane. The goal of this study is to determine the underlying mechanisms of sequential energy transfer from laser light to nanoparticle to fluid medium to cell. We found that laser pulses on a timescale of 10 ns rapidly heat carbon nanoparticles to temperatures on the order of 1200 K. Heat is transferred from the nanoparticles to the surrounding aqueous medium on a similar timescale, causing vaporization of the surrounding water and generation of acoustic emissions...
March 28, 2017: Biophysical Journal
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