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https://www.readbyqxmd.com/read/7847847/the-canine-p53-gene-is-subject-to-somatic-mutations-in-thypoid-carcinoma
#1
P Devilee, I S Van Leeuwen, A Voesten, G R Rutteman, J H Vos, C J Cornelisse
In many different types of tumors in man and mouse, p53 is the tumor suppressor gene most frequently affected by a combination of somatic mutation and loss of the wildtype allele. In order to develop a molecular tool to study the genetic evolution of tumors in the dog, we have cloned an evolutionary conserved part of the canine homologue of p53. The isolated genomic segment, 534 bp in length, contains the 3' half of exon 5, the complete exon 6 and the 5' half of exon 7, as well as the intronic intervening sequences...
September 1994: Anticancer Research
https://www.readbyqxmd.com/read/646883/-skin-response-to-phytohemagglutinin-in-patients-with-typhoid-fever-bronchial-asthma-and-hodgkin-s-disease
#2
COMPARATIVE STUDY
S Martínez-Cairo, J Espinosa Ayala, O Muñóz, L Winkler Bano
The skin response to phytohemagglutinin was investigated as an index of cellular immunity in group of 50 children made up of 11 with thypoid fever, 13 with bronchial asthma type I, 15 with Hodgkin's disease and 11 controls. A mild but statistically significant (p less than 0.005) depression was found in the skin response of patients with typhoid fever and moderate in patients with Hodgkin's disease. In patients with bronchial asthma, it was similar to control cases; thus, in the future, finer parameters are considered necessary in these cases to investigate cellular immunity...
July 1978: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/215245/-effect-of-potassium-iodide-and-perchlorate-on-the-process-of-thyroid-hormone-secretion
#3
Ia Kh Turakulov, N S Salakhova, T P Tashkhodzhaeva, S I Mirmakhmudova, N M Mullagalieva
The influence of potassium iodide and perchlorate on the parameters characterizing the thypoid hormones secretion, such as the cAMP level in the gland tissue and the number of intracellular colloid droplets under condition of stimulation by thyrotropic hormone was studied. It was shown that the abovementioned parameters were depressed by an excess of iodide, but perchlorate administration prevented the inhibitory effect of iodide. The results obtained favour the conception on the sensitivity of the thyroid adenylate cyclase system to the organic iodine concentration...
December 1978: Biulleten' Eksperimental'noĭ Biologii i Meditsiny
https://www.readbyqxmd.com/read/120734/epidemiology-of-diarrhoeal-diseases-in-singapore
#4
REVIEW
K T Goh
Diarrhoeal diseases in the form of bacterial food poisoning are prevalent in Singapore. Common food poisoning organisms implicated were Staphylococcus aureus, non-thypoid Salmonellae and Vibrio parahaemolyticus. El tor cholera, believed to be introduced through intra-regional trade and travel, occurred sporadically with a common source outbreak, probably food-borne, in September 1978. Shigellosis and amoebiasis were mainly confined to areas where poor personal hygiene was prevalent. The incidence of enteric favers (typhoid and paratyphoid) continued to decline with 39...
June 1979: Asian Journal of Infectious Diseases
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