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optical coherence tomography angiography

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https://www.readbyqxmd.com/read/29243353/first-in-human-evaluation-of-the-vascular-biocompatibility-and-biomechanical-performance-of-a-novel-ultra-high-molecular-weight-amorphous-plla-bioresorbable-scaffold-in-the-absence-of-anti-proliferative-drugs-two-year-imaging-results-in-humans
#1
Miguel Moncada, Juan A Delgado, Antonio Colombo, Pawel Gasior, Kamal Ramzipoor, Alex Estrada, Chang Lee, Danny Dokko, Juan F Granada
OBJECTIVES: In this first-in-human study, we prospectively studied the vascular compatibility and mechanical performance of a novel bare ultra-high molecular weight amorphous PLLA bioresorbable scaffold (BRS, FORTITUDE®, Amaranth Medical, Mountain View, California) up to two years after implantation using multimodality imaging techniques. BACKGROUND: The vascular biocompatibility of polymers used in BRS has not been fully characterized in the absence of anti-proliferative drugs...
December 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29234872/-multimodal-imaging-in-goldmann-favre-syndrome
#2
D Valler, M Ulbig, C P Lohmann, M Maier
Case report of a 23-year-old male patient suffering from Goldmann-Favre syndrome. The patient reported bilateral visual loss since 10 years of age and difficulties with dark adaptation for 2 years. Until recently a final diagnosis was not found. Multimodal imaging using multicolor fundus imaging (MCFI), optical coherence tomography (OCT), fundus autofluorescence (FAF), fluorescein angiography (FLA), electroretinography (ERG) and visual evoked potential (VEP) confirmed the diagnosis. We describe multimodal imaging of this rare hereditary retinal dystrophy...
December 12, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29232337/retinal-telangiectasia-in-patients-with-pathologic-myopia-a-case-series
#3
Boya Lei, Ruiping Gu, Chen Jiang, Gezhi Xu
PURPOSE: To describe the characteristics of retinal telangiectasia in eyes with pathologic myopia. METHODS: The study included 10 patients (18 eyes) who were diagnosed with pathologic myopia combined with retinal telangiectasia. The patients visited our retinal clinic every 3 months. Nine eyes underwent vitrectomy for vision-threatening complications after diagnosis. All eyes underwent comprehensive ophthalmologic examinations including multimodal retinal imaging at presentation and at each follow-up...
December 8, 2017: Retina
https://www.readbyqxmd.com/read/29232336/comparison-among-different-diagnostic-methods-in-the-study-of-type-and-activity-of-choroidal-neovascular-membranes-in-age-related-macular-degeneration
#4
Vittoria Ravera, Andrea Giani, Marco Pellegrini, Marta Oldani, Alessandro Invernizzi, Elisa Carini, Mario Cigada, Ferdinando Bottoni, Giovanni Staurenghi
PURPOSE: To determine interobserver and intraobserver agreement in classifying the subtypes of choroidal neovascularization (CNV) and the decision of retreatment in patients affected by exudative age-related macular degeneration. Different imaging techniques were evaluated individually and compared with multiimaging. METHODS: Fifty-two patients with naive CNV in age-related macular degeneration were evaluated after 3 monthly intravitreal injections of ranibizumab...
December 8, 2017: Retina
https://www.readbyqxmd.com/read/29232330/foveal-avascular-zone-area-analysis-using-optical-coherence-tomography-angiography-before-and-after-idiopathic-epiretinal-membrane-surgery
#5
Yorihisa Kitagawa, Hiroyuki Shimada, Ari Shinojima, Hiroyuki Nakashizuka
PURPOSE: To determine the size of the foveal avascular zone (FAZ) by optical coherence tomography angiography before and after idiopathic epiretinal membrane surgery. METHODS: Thirteen consecutive patients (13 eyes) with unilateral epiretinal membrane were studied retrospectively. Optical coherence tomography angiography was used to measure the FAZ area within 3 mm × 3 mm scans of the superficial (superficial FAZ) and deep plexus layers (deep FAZ) before and 6 months after vitrectomy...
December 11, 2017: Retina
https://www.readbyqxmd.com/read/29230338/optical-coherence-tomography-angiography-of-punctate-inner-choroidopathy
#6
Blake M Hampton, Christopher M Aderman, Harry W Flynn, Jayanth Sridhar
Purpose: To report a case of bilateral choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) visualized utilizing optical coherence tomography angiography (OCT-A). Methods: Case report. Results: A 29-year-old woman presented with new visual symptoms in both eyes. Fundoscopic exam revealed bilateral multifocal, small, well-defined lesions consistent with PIC. Optical coherence tomography demonstrated subretinal fluid and retinal pigment epithelium detachments (RPEDs) in both eyes...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29229445/optical-coherence-tomography-angiography
#7
REVIEW
Richard F Spaide, James G Fujimoto, Nadia K Waheed, Srinivas R Sadda, Giovanni Staurenghi
Optical coherence tomography (OCT) was one of the biggest advances in ophthalmic imaging. Building on that platform, OCT angiography (OCTA) provides depth resolved images of blood flow in the retina and choroid with levels of detailed far exceeding that obtained with older forms of imaging. This new modality is challenging because of the need for new equipment and processing techniques, current limitations of imaging capability, and rapid advancements in both imaging and in our understanding of the imaging and applicable pathophysiology of the retina and choroid, and the requirement for understanding the origins of image artifacts...
December 8, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29227980/spectral-domain-optical-coherence-tomography-angiography-for-the-diagnosis-and-evaluation-of-polypoidal-choroidal-vasculopathy
#8
Talisa E de Carlo, Gregg T Kokame, Jessica G Shantha, James C Lai, Raymond Wee
PURPOSE: To compare the diagnostic ability of optical coherence tomography angiography (OCTA) with indocyanine green angiography (ICGA) in polypoidal choroidal vasculopathy (PCV). METHODS: Retrospective review of 47 eyes with PCV imaged with ICGA and OCTA. For each eye, it was determined which imaging modality better delineated the PCV complex. The presence of a branching vascular network (BVN) and polyp(s) were noted. RESULTS: PCV was better visualized with ICGA in 21 eyes (44...
December 11, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29224472/preoperative-assessment-of-computerized-tomography-angiography-to-predict-success-for-crossing-long-trans-atlantic-inter-society-consensus-d-lesions-using-the-optical-coherence-tomography-catheter
#9
Ryan J Kim, Jamie B Smith, Todd R Vogel
Objectives Optical coherence tomography chronic total occlusion catheter, the Ocelot (Avinger Inc., Redwood City, CA), has been utilized to cross Trans-Atlantic Inter-Society Consensus D lesions. This study evaluated the preoperative computerized tomography angiography of chronic total occlusions in the superficial femoral artery to predict clinical success. Methods We reviewed all patients who underwent lower extremity procedures with the Ocelot catheter from June 2014 to August 2016. Patients who had a preoperative computerized tomography angiography were evaluated...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/29222532/acute-solar-retinopathy-imaged-with-adaptive-optics-optical-coherence-tomography-angiography-and-en-face-optical-coherence-tomography
#10
Chris Y Wu, Michael E Jansen, Jorge Andrade, Toco Y P Chui, Anna T Do, Richard B Rosen, Avnish Deobhakta
Importance: Solar retinopathy is a rare form of retinal injury that occurs after direct sungazing. Objective: To enhance understanding of the structural changes that occur in solar retinopathy by obtaining high-resolution in vivo en face images. Design, Setting, and Participant: Case report of a young adult woman who presented to the New York Eye and Ear Infirmary with symptoms of acute solar retinopathy after viewing the solar eclipse on August 21, 2017...
December 7, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29220112/multispectral-image-analysis-in-vogt-koyanagi-harada-disease
#11
Guo Huang, Junchao Peng, Zi Ye, Aize Kijlstra, Donglei Zhang, Peizeng Yang
PURPOSE: To investigate fundus abnormalities in Vogt-Koyanagi-Harada (VKH) disease by a noninvasive tool, multispectral imaging (MSI). METHODS: A total of 77 patients with VKH and 163 healthy controls were enrolled between January and April 2015. The MSI findings were evaluated in combination with fundus fluorescein angiography (FFA), optical coherent tomography (OCT) and fundus photography (FP). Additionally, we compared extent of exposure of choroidal blood vessels between patients with VKH and healthy controls to evaluate retinal transmission function...
December 8, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29219932/cuticular-drusen-in-an-indigenous-australian
#12
William J Cunningham, Chandrakumar Balaratnasingam, Yi Chen, Fred K Chen
BACKGROUND/PURPOSE: To report a case of cuticular drusen in an indigenous Australian. METHODS: A 37-year-old indigenous (aboriginal) Australian woman from a remote Western Australian town presented with a 2-month history of vision loss. Clinical history, examination, and multimodal retinal imaging data from spectral domain optical coherence tomography, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography were analyzed. RESULTS: Multimodal imaging confirmed cuticular drusen complicated by a right choroidal neovascularization with pigment epithelial detachment and a left foveal vitelliform lesion...
December 5, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29217514/novel-ocular-toxicity-associated-with-fibroblast-growth-factor-receptor-fgfr-inhibitors-in-cancer-treatment-observational-case-series
#13
Daniel Velazquez-Villoria, Analia Azaro, Jordi Rodon, Cinta Hierro, Danai Kyriakou, Jose Garcia-Arumi, Miguel Angel Zapata
AIMS: To describe novel ocular toxicity in patients with metastatic cancer undergoing chemotherapy with fibroblast growth factor receptor (FGFR) inhibitors. METHODS: This observational case series study included five patients with advanced cancer who received selected pan-FGFR inhibitors as single chemotherapy in the framework of a dose-finding study and phase I and phase II clinical studies. In all cases, subfoveal neurosensory retinal detachment was diagnosed...
December 7, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29216976/ivus-guided-versus-oct-guided-coronary%C3%A2-stent-implantation-a-critical-appraisal
#14
REVIEW
Akiko Maehara, Mitsuaki Matsumura, Ziad A Ali, Gary S Mintz, Gregg W Stone
Procedural guidance with intravascular ultrasound (IVUS) imaging improves the clinical outcomes of patients undergoing percutaneous coronary intervention (PCI) by: 1) informing the necessity for lesion preparation; 2) directing appropriate stent sizing to maximize the final stent area and minimize geographic miss; 3) selecting the optimal stent length to cover residual disease adjacent to the lesion, thus minimizing geographic miss; 4) guiding optimal stent expansion; 5) identifying acute complications (edge dissection, stent malapposition, tissue protrusion); and 6) clarifying the mechanism of late stent failure (stent thrombosis, neointimal hyperplasia, stent underexpansion or fracture, or neoatherosclerosis)...
December 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29216118/adaptive-classifier-allows-enhanced-flow-contrast-in-oct-angiography-using-a-histogram-based-motion-threshold-and-3d-hessian-analysis-based-shape-filtering
#15
Peng Li, Zhiyu Huang, Shanshan Yang, Xi Liu, Qiushi Ren, Pei Li
In this Letter, we propose an adaptive digital classifier for flow contrast enhancement in optical coherence tomography angiography (OCTA). To solve the depth dependence in the initial motion-based classification, a depth-adaptive motion threshold was determined by performing a histogram analysis of an en-face image at each depth and identifying the static and dynamic voxel populations through fitting. In the follow-up shape-based classification, to adapt to the deformed vessel shapes in OCTA, a modified vesselness function along with an anisotropic Gaussian probe kernel was defined, and then a three-dimensional (3D) Hessian analysis-based shape filtering was utilized for effectively removing the residual static voxels...
December 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/29215469/multimodality-coronary-imaging-to-predict-periprocedural-myocardial-necrosis-after-an-elective-percutaneous-coronary-intervention
#16
Masahiro Hoshino, Taishi Yonetsu, Tadashi Murai, Yoshihisa Kanaji, Eisuke Usui, Masao Yamaguchi, Masahiro Hada, Rikuta Hamaya, Yoshinori Kanno, Tetsumin Lee, Tsunekazu Kakuta
BACKGROUND: Although multiple imaging modalities have been tested to predict periprocedural myocardial necrosis (PMN), the superior predictive efficacy of these imaging findings has not been established fully. We sought to evaluate which findings of the coronary imaging tools would best provide predictive efficacy of PMN among optical coherence tomography (OCT), intravascular ultrasound (IVUS), and coronary computed tomography (CCT) angiography. PATIENTS AND METHODS: A total of 130 patients with stable angina pectoris who underwent OCT, IVUS, and CCT examinations for a single de-novo preprocedural lesion were investigated...
December 5, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29214344/-oct-angiography-in-diabetic-maculopathy-comparison-between-microaneurysms-and-the-foveal-avascular-zone-with-flourescein-angiography
#17
S Henke, I Papapostolou, B Heimes, A Lommatzsch, D Pauleikhoff, G Spital
BACKGROUND: Optical coherence tomography angiography allows an exact visualization of retinal vascular changes. To interpret the possibilities and limitations using OCTA in clinical practice, we analysed the quality of OCTA findings concerning the evaluability. Furthermore, we correlated our OCTA findings with fluorescein angiography (FAG) in relation of the presence of microaneurysms (MA) and enlargement of the foveal avascular zone (FAZ) in diabetic maculopathy. PATIENTS AND METHODS: 30 eyes from 15 patients with diabetic maculopathy were imaged in 3 × 3mm volume scans and were depicted in OCTA mode (SSADA algorithm)...
December 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29212537/association-of-arms2-genotype-with-response-to-anti-vascular-endothelial-growth-factor-treatment-in-polypoidal-choroidal-vasculopathy
#18
Un Chul Park, Joo Young Shin, Hum Chung, Hyeong Gon Yu
BACKGROUND: To investigate whether genetic risk variants for age-related macular degeneration (AMD) are associated with response to intravitreal anti-vascular endothelial growth factor (VEGF) in polypoidal choroidal vasculopathy (PCV) patients. METHODS: This prospective cohort study included 95 treatment-naïve patients that underwent anti-VEGF treatment for PCV for 12 months. Patients were genotyped for 10 single nucleotide polymorphisms in eight AMD-relevant genes...
December 7, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29210964/perivascular-granulomata-in-the-retina-demonstrated-by-en-face-optical-coherence-tomography-in-a-patient-with-blau-syndrome
#19
Erika T Friesen, Nopasak Phasukkijwatana, Irena Tsui, Meghan K Berkenstock, Gary N Holland, David Sarraf
PURPOSE: To describe the multimodal retinal imaging findings of a case of Blau syndrome. METHODS: Case report. The multimodal retinal imaging findings, including widefield angiography, cross-sectional and en face spectral domain optical coherence tomography, and optical coherence tomography angiography, of a case of Blau syndrome are described. RESULTS: A 12-year-old Hispanic girl with polyarticular arthritis, skin rash, and panuveitis was diagnosed with a rare condition referred to as Blau syndrome...
November 23, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29210959/acute-frosted-retinal-periphlebitis-in-a-patient-with-mediterranean-fever
#20
Köse Özlem, Willermain François, Caspers Laure, Postelmans Laurence, El Ouardighi Hind, Guillaume Marie-Paule, Makhoul Dorine
PURPOSE: To present a case of frosted branch periphlebitis in a young Armenian patient with familial Mediterranean fever. METHODS: Case report. RESULTS: A 37-year-old man presented with a unilateral decreased visual acuity and floaters for 4 days on the left eye (LE). Visual acuity was 20/20 in the right eye (RE) and 20/28 in the LE. Anterior segment and fundus examinations of the RE were normal. Slit-lamp examination of LE revealed a mild nongranulomatous anterior uveitis and vitritis...
November 23, 2017: Retinal Cases & Brief Reports
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