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optical coherence tomography angiography

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https://www.readbyqxmd.com/read/29456174/bilateral-maculopathy-after-exposure-to-a-laser-pointer-optical-coherence-tomography-angiography-findings
#1
R Clemente-Tomás, P Bayo-Calduch, P Neira-Ibáñez, A Gargallo-Benedicto, A M Duch-Samper
CASE REPORT: A 36-year-old man went to the emergency department the day after exposure to a laser pointer. Funduscopy revealed dispersed macular pigment alterations, and optical coherence tomography showed a disruption of the retinal layers. The visual acuity was counting fingers in both eyes. Nine months later, optical coherence tomography angiography showed a rarefaction in the choriocapillaris vascular flow in the area of the laser injuries. DISCUSSION: The retinal layer mainly damaged by the laser injury was the retinal pigment epithelium...
February 15, 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29454763/early-strut-coverage-in-patients-receiving-drug-eluting-stents-and-its-implications-for-dual-antiplatelet-therapy-a-randomized-trial
#2
Seung-Yul Lee, Jung-Sun Kim, Hyuck-Jun Yoon, Seung-Ho Hur, Sang-Gon Lee, Jin Won Kim, Young Joon Hong, Ki-Seok Kim, So-Yeon Choi, Dong-Ho Shin, Chung-Mo Nam, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong
OBJECTIVES: This study sought to measure early strut coverage in patients receiving drug-eluting stents (DESs) and to explore the feasibility of short-term dual antiplatelet therapy (DAPT) based on the degree of early strut coverage. BACKGROUND: Data for early strut coverage in patients receiving new-generation DESs, and its implications for DAPT continuation were limited. METHODS: A randomized, multicenter trial was conducted in 894 patients treated with DESs...
February 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29453673/optical-coherence-tomography-angiography-discerns-preclinical-diabetic-retinopathy-in-eyes-of-patients-with-type-2-diabetes-without-clinical-diabetic-retinopathy
#3
Dan Cao, Dawei Yang, Zhongning Huang, Yunkao Zeng, Jun Wang, Yunyan Hu, Liang Zhang
AIMS: To investigate changes in retinal vascular plexuses and choriocapillaris in patients with type 2 diabetes mellitus (DM2) without diabetic retinopathy (DR) and healthy controls using optical coherence tomography angiography (OCTA). METHODS: A total of 71 DM2 and 67 healthy control subjects were included. All subjects underwent OCTA examination (RTVue-XR Avanti; Optovue, Fremont, CA, USA). Average vessel density in superficial capillary plexus (SCP), deep capillary plexus (DCP) and choriocapillaris, parafoveal vessel density in SCP and DCP, FAZ area (mm 2 ) in SCP, microaneurysms and capillary nonperfusion were taken into analysis...
February 16, 2018: Acta Diabetologica
https://www.readbyqxmd.com/read/29451996/foveal-avascular-zone-area-changes-analyzed-using-oct-angiography-after-successful-rhegmatogenous-retinal-detachment-repair
#4
Je Moon Woo, Yo Sep Yoon, Jong Eun Woo, Jung Kee Min
PURPOSE: To investigate foveal avascular zone (FAZ) area after surgery in patients with rhegmatogenous retinal detachment (RRD) that involved or uninvolved the macula, and to evaluate the correlation between FAZ area and visual outcomes using swept-source optical coherence tomography angiography (OCTA). MATERIALS AND METHODS: This retrospective case-control study included 34 eyes (34 patients) with recent onset RRD that were successfully repaired with a single, uncomplicated surgical procedure (pars plana vitrectomy with gas tamponade)...
February 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29451992/optical-coherence-tomography-angiography-of-the-peripapillary-retina-in-normal-tension-glaucoma-and-chronic-nonarteritic-anterior-ischemic-optic-neuropathy
#5
Rodolfo Mastropasqua, Luca Agnifili, Enrico Borrelli, Vincenzo Fasanella, Lorenza Brescia, Luca Di Antonio, Leonardo Mastropasqua
PURPOSE: To analyze the retinal radial peripapillary capillary (RPC) network in normal-tension glaucoma (NTG) and nonarteritic anterior ischemic optic neuropathy (NAION) eyes using optical coherence tomography angiography (OCTA). MATERIAL AND METHODS: Twenty-two patients with NTG, 22 patients with unilateral chronic NAION, and 23 age-matched controls were enrolled. Patients underwent OCTA to obtain en face angiograms of the peripapillary region. The main outcome measures were as follows: (1) the whole en face image perfusion density (WPD) and (2) the circumpapillary perfusion density (CPD)...
February 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29450622/comparison-of-retinal-microvascular-changes-in-eyes-with-high-tension-glaucoma-or-normal-tension-glaucoma-a-quantitative-optic-coherence-tomography-angiographic-study
#6
Huan Xu, Ruyi Zhai, Yuan Zong, Xiangmei Kong, Chunhui Jiang, Xinghuai Sun, Yi He, Xiqi Li
PURPOSE: The aim of this study is to determine and compare the changes in the retinal vasculature in eyes with high-tension glaucoma (HTG) or normal-tension glaucoma (NTG). METHODS: The right eyes of 43 HTG subjects, 33 NTG subjects, and 51 age- and sex-matched normal subjects were included in this cross-sectional study. Signals were projected from the internal limiting membrane to retinal pigment epithelium. The retinal perfused vessel densities in the peripapillary and parafoveal regions were measured automatically with optic coherence tomography angiography and the split-spectrum amplitude-decorrelation angiography algorithm...
February 15, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29450547/aflibercept-action-in-a-rabbit-model-of-chronic-retinal-neovascularization-reversible-inhibition-of-pathologic-leakage-with-dose-dependent-duration
#7
Jingtai Cao, Thomas C MacPherson, Bibiana V Iglesias, Yang Liu, Natasha Tirko, George D Yancopoulos, Stanley J Wiegand, Carmelo Romano
Purpose: We establish and characterize the chronic retinal neovascularization (RNV) induced by intravitreal (IVT) injection of DL-α-aminoadipic acid (AAA) in a rabbit model and investigate the extent and duration of inhibitory actions induced by IVT aflibercept on the RNV. Methods: Rabbits received a single IVT injection of AAA, with weekly follow-up fundus photography, fluorescein angiography (FA), and optical coherence tomography (OCT). After 10 weeks, they received a single IVT aflibercept or control injection...
February 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29448042/quantitative-comparisons-between-optical-coherence-tomography-angiography-and-matched-histology-in-the-human-eye
#8
Dong An, Chandrakumar Balaratnasingam, Morgan Heisler, Ashley Francke, MyeongJin Ju, Ian L McAllister, Marinko Sarunic, Dao-Yi Yu
The aim was to quantitatively compare retinal vascular detail as seen on optical coherence tomography angiography (OCTA) and matched histology in the human eye. 13 normal human donor eyes were used. The central retinal artery was cannulated after which human packed red blood cells were perfused through the retinal vasculature. Retinal vessels were imaged using a custom-built OCTA device during red blood cell perfusion. The eye was subsequently perfused with endothelial cell antibodies and the flat-mounted retina studied histologically using a confocal scanning laser microscope...
February 12, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29443808/retinal-microvasculature-alteration-in-paracentral-acute-middle-maculopathy-and-acute-macular-neuroretinopathy-a-quantitative-optical-coherence-tomography-angiography-study
#9
Alexei N Kulikov, Dmitrii S Maltsev, Tatiana A Leongardt
PURPOSE: To present a series of idiopathic paracentral acute middle maculopathy (PAMM) and acute macular neuroretinopathy (AMN) cases and to compare the microvascular retinal status of PAMM/AMN eyes with those of healthy individuals. METHODS: Six eyes with PAMM and two eyes with AMN in a total of six patients were included in this study. Multimodal retinal imaging, including optical coherence tomography angiography, was performed in all patients. The vessel density of the superficial capillary plexus and deep capillary plexus, as well as the area, circularity, and angle of the superficial foveal avascular zone (FAZ) were measured and compared with the same parameters in age-matched healthy individuals...
February 13, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29443807/multimodal-imaging-of-angioid-streaks-associated-with-turner-syndrome
#10
Bing Q Chiu, Edmund Tsui, Syed Amal Hussnain, Irene A Barbazetto, R Theodore Smith
PURPOSE: To report multimodal imaging in a novel case of angioid streaks in a patient with Turner syndrome with 10-year follow-up. METHODS: Case report of a patient with Turner syndrome and angioid streaks followed at Bellevue Hospital Eye Clinic from 2007 to 2017. Fundus photography, fluorescein angiography, and optical coherence tomography angiography were obtained. RESULTS: Angioid streaks with choroidal neovascularization were noted in this patient with Turner syndrome without other systemic conditions previously correlated with angioid streaks...
February 13, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29443804/progression-of-retinal-ischemia-in-a-case-of-macular-telangiectasia-type-1-after-ranibizumab-injection-optical-coherence-tomography-angiography-findings
#11
Massimo Lorusso, Roberta Zito, Eleni Nikolopoulou, Luisa Micelli Ferrari, Maria Vittoria Cicinelli, Giuseppe Querques, Tommaso Micelli Ferrari
PURPOSE: To describe a case of a 68-year-old man with macular telangiectasia (MacTel) Type 1 in the right eye, showing an increase in capillary ischemia after intravitreal ranibizumab. METHODS: The patient underwent complete ophthalmologic evaluation, including best-corrected visual acuity, intraocular pressure, anterior segment and fundus examination, optical coherence tomography (OCT), and OCT angiography at baseline and on each visit. Fluorescein angiography was performed at baseline...
February 13, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29443803/newly-diagnosed-asymptomatic-retinal-astrocytic-hamartoma-in-an-older-adult
#12
A Kaan Gündüz, Carol L Shields, Gökçen Çöndü, Ragıp Gürsel
BACKGROUND: To report a coincidentally discovered retinal astrocytic hamartoma in an asymptomatic older woman with no history of tuberous sclerosis or neurofibromatosis. METHODS: A 63-year-old Turkish woman underwent routine ophthalmic examination. RESULTS: Visual acuity was 20/25 in each eye. On fundus examination, the right eye showed a flat yellow-white superficial retinal lesion in the inferotemporal macula and measuring 1 mm in diameter...
February 13, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29443780/analysis-of-the-characteristics-of-optical-coherence-tomography-angiography-for-retinal-cavernous-hemangioma-a-case-report
#13
Shuyuan Lyu, Ming Zhang, Ruikang K Wang, Yunxia Gao, Qinqin Zhang, Xiaoxue Min
RATIONALE: Retinal cavernous hemangioma is a rare congenital vascular malformation with typical fundus changes. Optical coherence tomography angiography (OCTA), which is in rise in the recent years, is a rapid and noninvasive technology to assist in obtaining information regarding the blood flow changes in the fundus lesions from different layers without injecting a contrast agent. PATIENT CONCERNS: A 40-year-old male patient with visual occlusion in the right eye for >1 month was reported...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443367/swept-source-oct-angiography-of-multiple-evanescent-white-dot-syndrome-with-inflammatory-retinal-pigment-epithelial-detachment
#14
Swarup S Swaminathan, Fang Zheng, Andrew R Miller, Giovanni Gregori, Janet L Davis, Philip J Rosenfeld
A 30-year-old woman with photopsias and decreased vision was diagnosed with multiple evanescent white dot syndrome (MEWDS) with an atypical inflammatory subfoveal retinal pigment epithelial detachment (PED) and imaged using swept-source optical coherence tomography (SS-OCT) during several visits. SS-OCT imaging revealed a focal area of attenuated choriocapillaris underneath the PED. An attempt to treat the presumed macular inflammatory lesion with corticosteroids resulted in bilateral exudation consistent with central serous chorioretinopathy...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29443365/detection-of-choriocapillaris-loss-in-alport-syndrome-with-swept-source-oct-angiography
#15
Swarup S Swaminathan, Parth Shah, Fang Zheng, Giovanni Gregori, Philip J Rosenfeld
A patient previously diagnosed with Alport Syndrome was evaluated using multimodal imaging. Optical coherence tomography (OCT) demonstrated significant thinning of the inner retina within the macula, and inner retinal cysts were found in the peripheral macula. OCT angiography demonstrated loss of the choriocapillaris. Abnormal collagen appears to have multiple deleterious effects on the retinal and choroidal structure and vasculature. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:138-141.].
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29443361/optical-coherence-tomography-angiography-of-the-macula-in-adults-with-a-history-of-preterm-birth
#16
Khalil Ghasemi Falavarjani, David Sarraf, Irena Tsui
BACKGROUND AND OBJECTIVE: To evaluate the fovea microvasculature in adult subjects with history of preterm birth using optical coherence angiography (OCTA). PATIENTS AND METHODS: In this retrospective study, macular OCTA images were obtained from adult subjects with a history of preterm birth. The presence of the foveal avascular zone (FAZ) and its size was determined. RESULTS: Ten eyes from six subjects with ages ranging from 26 years old to 65 years old were evaluated...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29443360/swept-source-oct-angiography-of-full-thickness-macular-holes-appearance-and-artifacts
#17
Zofia Michalewska, Jerzy Nawrocki
BACKGROUND AND OBJECTIVE: To evaluate swept-source optical coherence tomography angiography (SS-OCTA) images in full-thickness macular holes (FTMHs). PATIENTS AND METHODS: SS-OCTA of FTMHs was performed before or after surgery. Vitrectomy with the temporal inverted internal limiting membrane flap technique was used. The authors measured the diameter and area of the foveal avascular zone (FAZ) in superficial and deep retina vasculature. RESULTS: In 88 patients, two artifact types were observed...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29443356/use-of-optical-coherence-tomography-angiography-in-masqueraders-of-wet-age-related-macular-degeneration-and-choroidal-neovascularization
#18
Sidney Schechet, Seenu M Hariprasad, Asadolah Movahedan, Dimitra Skondra
No abstract text is available yet for this article.
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29443029/in-vivo-multimodal-imaging-and-analysis-of-mouse-laser-induced-choroidal-neovascularization-model
#19
Symantas Ragauskas, Eva Kielczewski, Joseph Vance, Simon Kaja, Giedrius Kalesnykas
Laser-induced choroidal neovascularization (CNV) is a well-established model to mimic the wet form of age-related macular degeneration (AMD). In this protocol, we aim to guide the reader not simply through the technical considerations of generating laser-induced lesions to trigger neovascular processes, but rather focus on the powerful information that can be obtained from multimodal longitudinal in vivo imaging throughout the follow-up period. The laser-induced mouse CNV model was generated by a diode laser administration...
January 21, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29439809/optical-coherence-tomography-angiography-present-or-future-in-daily-clinical-practice
#20
R Abreu-González, R Dolz-Marco, L López-Guajardo, J Donate-López, R Gallego-Pinazo
No abstract text is available yet for this article.
February 10, 2018: Archivos de la Sociedad Española de Oftalmología
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