Matteo Airaldi, Yalin Zheng, Francesco Aiello, Björn Bachmann, Lamis Baydoun, Sorcha Ní Dhubhghaill, Mor M Dickman, Stephen B Kaye, Luigi Fontana, Kunal A Gadhvi, Antonello Moramarco, Marina Rodriguez Calvo de Mora, Carlos Rocha de Lossada, Vincenzo Scorcia, Pietro Viola, Stefano Calza, Hannah J Levis, Mohit Parekh, Alessandro Ruzza, Stefano Ferrari, Diego Ponzin, Francesco Semeraro, Vito Romano
INTRODUCTION: The success of keratoplasty strongly depends on the health status of the transplanted endothelial cells. Donor corneal tissues are routinely screened for endothelial damage before shipment; however, surgical teams have currently no means of assessing the overall viability of corneal endothelium immediately prior to transplantation. The aim of this study is to validate a preoperative method of evaluating the endothelial health of donor corneal tissues, to assess the proportion of tissues deemed suitable for transplantation by the surgeons and to prospectively record the clinical outcomes of a cohort of patients undergoing keratoplasty in relation to preoperatively defined endothelial viability...
September 2023: BMJ Open Ophthalmology