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Descemet's stripping automated endothelial keratoplasty

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https://www.readbyqxmd.com/read/29781928/interface-fungal-keratitis-after-descemet-stripping-automated-endothelial-keratoplasty-a-review-of-the-literature-with-a-focus-on-outcomes
#1
Elizabeth McElnea, Billy Power, Conor Murphy
PURPOSE: To examine the management and associated outcomes of reported cases of interface fungal infection after Descemet stripping automated endothelial keratoplasty (EK). METHODS: A literature review identified reports of interface fungal infection after Descemet stripping automated EK. Data retrieved from the same included patient demographics, surgical procedure undertaken, donor rim culture result, clinical course, and outcome. A review of the relevant literature was also conducted...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29781926/repeatability-and-intersession-reproducibility-of-pentacam-corneal-thickness-maps-in-fuchs-dystrophy-and-endothelial-keratoplasty
#2
David Mingo-Botín, Francisco Arnalich-Montiel, Ana Couceiro de Juan, Sara Ortiz-Toquero
PURPOSE: To assess intrasession repeatability and intersession reproducibility of Pentacam corneal thickness maps in patients with Fuchs endothelial corneal dystrophy (FECD) before and after endothelial transplantation. METHODS: In this observational diagnostic evaluation, 20 healthy subjects along with 81 consecutive patients were examined. Patients were classified into 4 groups: FECD without corneal edema, FECD with corneal edema, Descemet stripping automated endothelial keratoplasty, and Descemet membrane endothelial keratoplasty...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29737416/long-term-follow-up-of-deep-anterior-lamellar-keratoplasty-after-descemet-stripping-automated-endothelial-keratoplasty
#3
Matthias Fuest, Sharita R Siregar, Abdelsattar Farrag, Hla Myint Htoon, Donald Tan, Jodhbir S Mehta
AIMS: To describe the long-term outcomes of deep anterior lamellar keratoplasty (DALK) performed after Descemet stripping automated endothelial keratoplasty (DSAEK) in cases of infection and residual stromal opacity. METHODS: Ten eyes of nine consecutive patients undergoing DALK after DSAEK at a single tertiary referral center (SNEC) from 2011 to 2016 were analyzed for best spectacle-corrected visual acuity (BSCVA), refraction, spherical equivalent (SE) and cylinder, as well as graft diameters, survival, and complications...
May 8, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29713526/long-term-functional-and-anatomical-outcome-after-descemet-stripping-automated-endothelial-keratoplasty-a-prospective-single-center-study
#4
Jeroen van Rooij, Angela Engel, Lies Remeijer, Hugo van Cleijnenbreugel, René Wubbels
Purpose: To investigate the long-term anatomical and functional outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK). Methods: Prospective follow-up of 114 eyes (95 subjects) after DSAEK for endothelial dysfunction. Measurements included best spectacle-corrected visual acuity (BSCVA), straylight, endothelial cell density (ECD), and graft thickness. Results: The mean follow-up time was 5.1 ± 1.5 years. Four grafts ultimately failed (after 5 to 7 years)...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29681843/wheel-spokes-technique-for-endothelial-keratoplasty-for-extremely-mydriatic-bullous-keratopathy-eyes-without-capsular-support
#5
Hidenori Tanaka, Koji Hirano, Masayuki Horiguchi
We describe a new technique to prevent an endothelial donor graft from dropping into the vitreous cavity during non-Descemet stripping automated endothelial keratoplasty (nDSAEK) for extremely mydriatic bullous keratopathy (BK) eyes without capsular support. The patient was a 79-year-old woman who underwent nDSAEK for an extremely mydriatic BK eye with an incomplete barrier between the anterior and posterior chambers. She had undergone argon laser iridotomy for acute glaucoma at the age of 59 years and cataract surgery 3 years later...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29681841/triamcinolone-acetonide-assisted-descemetectomy-for-retained-descemet-membrane
#6
Ariel Tyring, Oliver Chang, Hoon Jung
We present a case of decreased vision due to the presence of retained Descemet membrane (DM) following Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PKP). A 78-year-old male presented postoperatively from PKP after previous failed DSAEK with retained DM. We present a unique technique for combined surgical resection using bimanual vitrectomy and forceps excision assisted by triamcinolone acetonide for membrane visualization. Histopathological evaluation confirmed incomplete DM removal during the PKP...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29679087/optical-and-tectonic-corneal-transplant-outcomes-in-a-tertiary-hospital-in-singapore-within-the-singapore-corneal-transplant-registry
#7
Dawn Ho, Charmaine Chai, Hazel Lin, Hla Myint Htoon, Anna Marie Tan, Ray Manotosh, Donald Tan
INTRODUCTION: This study aimed to describe and compare corneal graft survival and optical outcomes following deep anterior lamellar keratoplasty (DALK) and Descemet's stripping automated endothelial keratoplasty (DSAEK) with penetrating keratoplasty (PK), and to document tectonic success of patch grafts. MATERIALS AND METHODS: This was a retrospective, non-randomised, comparative and descriptive cohort study. A total of 139 eyes that underwent primary keratoplasty between 2000 and 2016 were included, and the following data was extracted: demographics, clinical diagnosis and primary indication, pre- and intraoperative risk factors, postkeratoplasty outcomes, and complications...
March 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29676320/unveiling-opacification-of-intraocular-lens-following-a-successful-penetrating-keratoplasty-for-extensively-scarred-cornea-due-to-microbial-keratitis-after-descemet-s-stripping-automated-endothelial-keratoplasty
#8
https://www.readbyqxmd.com/read/29675378/complications-and-outcomes-of-descemet-stripping-automated-endothelial-keratoplasty-with-artisan-aphakia-intraocular-lens-implantation
#9
Rong-Mei Peng, Yu-Xin Guo, Yuan Qiu, Yan-Sheng Hao, Jing Hong
AIM: To evaluate the complications and outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) combined with artisan aphakia intraocular lens (IOL) implantation in severely damaged eyes without capsular support. METHODS: DSAEK combined with artisan iris claw IOL implantation was performed on 29 eyes. All eyes were of abnormal structure due to complications from prior intraocular surgeries and ocular trauma. Ocular complications observed included graft dislocations, high intraocular pressure (IOP), IOL dislocations, macular edema and hyphema...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675350/postoperative-intraocular-lens-opacification
#10
Shang-Te Ma, Chung-May Yang, Yu-Chih Hou
Intraocular lens (IOL) opacification is rare but may occur after non-Descemet stripping automated endothelial keratoplasty (n-DSAEK) or intravitreal air injection after pars plana vitrectomy (PPV). We reported two cases of IOL opacification within the pupillary region. Chart was retrospectively reviewed. The predisposing factors and the visual acuity were analyzed. The opacification was evaluated by anterior segment optical coherence tomography (AS-OCT). A 68-year-old healthy woman with pseudophakic bullous keratopathy underwent uneventful n-DSAEK in the right eye...
January 2018: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29673628/-descemet-s-membrane-endothelial-keratoplasty-indication-surgical-technic-postoperative-management-and-review-of-literature
#11
REVIEW
V Kocaba, O Damour, C Auxenfans, C Burillon
Endothelial keratoplasty is currently the preferred method for the treatment of endothelial dysfunctions and dystrophies. Descemet Membrane Endothelial Keratoplasty (DMEK), described by Gerrit Melles in 2006, is performed by selectively replacing the damaged endothelium with a healthy counterpart. It leads to a faster visual recovery and better refractive outcomes with a limited risk of rejection compared to Descemet's Stripping Automated Endothelial Keratosplasty (DSAEK), which includes a thin stromal layer...
April 17, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29664749/meta-analysis-of-descemet-membrane-endothelial-keratoplasty-versus-descemet-stripping-automated-endothelial-keratoplasty-postoperative-visual-outcomes
#12
https://www.readbyqxmd.com/read/29661044/dmek-versus-dsaek-for-fuchs-endothelial-dystrophy-a-meta-analysis
#13
Raquel Esteves Marques, Paulo Silva Guerra, David Cordeiro Sousa, Ana Inês Gonçalves, Ana Miguel Quintas, Walter Rodrigues
PURPOSE: To compare the safety and efficacy profiles of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in adult patients with Fuchs' endothelial dystrophy. METHODS: Electronic database search on MEDLINE and CENTRAL from inception to August 2017. We included all comparative studies of DMEK versus DSAEK in patients with diagnosed Fuchs' endothelial dystrophy. Studies assessing rescue procedures were excluded to minimize bias...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29643797/uneventful-anterior-migration-of-intravitreal-ozurdex-implant-in-a-patient-with-iris-sutured-intraocular-lens-and-descemet-stripping-automated-endothelial-keratoplasty
#14
Andleeb Zafar, Ioannis M Aslanides, Vasileios Selimis, Konstantinos I Tsoulnaras, David Tabibian, George D Kymionis
Purpose: We report here the case of a patient with anterior segment migration of intravitreal dexamethasone implant as well as its management and outcome. Methods: The patient had the following sequence of events: complicated cataract surgery, iris-sutured intraocular lens implant, followed by cystoid macular edema treated with intravitreal Avastin, retinal vein occlusion treated with intravitreal dexamethasone implant, corneal decompensation treated with Descemet stripping automated endothelial keratoplasty (DSAEK), and finally recurrence of macular edema treated with repeated intravitreal dexamethasone implant...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29521689/outcomes-of-descemet-membrane-endothelial-keratoplasty-in-eyes-with-a-previous-descemet-stripping-automated-endothelial-keratoplasty-graft
#15
Nir Sorkin, Mahmood Showail, Adi Einan-Lifshitz, Tanguy Boutin, Armand Borovik, Mohammad Kreimei, Amir Rosenblatt, Clara C Chan, David S Rootman
PURPOSE: To analyze the outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with previous Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: This retrospective interventional case series included 26 eyes (26 patients) that underwent DMEK to replace a previous DSAEK graft with at least 6 months of follow-up. The outcome measures were indications for surgery, best spectacle-corrected visual acuity (BSCVA), endothelial cell density, rebubbling rate, rejection, and failure...
June 2018: Cornea
https://www.readbyqxmd.com/read/29504956/hypoxia-and-the-prolyl-hydroxylase-inhibitor-fg-4592-protect-corneal-endothelial-cells-from-mechanical-and-perioperative-surgical-stress
#16
Yogesh Bhadange, Jeferson Lautert, Shimin Li, Edward Lawando, Edward T Kim, Mark C Soper, Francis W Price, Marianne O Price, Joseph A Bonanno
PURPOSE: To determine whether hypoxia preconditioning can protect corneal endothelial cells from mechanical stress and perioperative procedures mimicking Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Preconditioning was delivered by 2 hours of 0.5% oxygen incubation in a hypoxia chamber or by exposure to the prolyl hydroxylase inhibitor FG-4592, which prevents hypoxia-inducible factor-1 alpha degradation. Damage to whole corneas was produced by brief sonication...
April 2018: Cornea
https://www.readbyqxmd.com/read/29487754/modified-descemet-s-stripping-automated-endothelial-keratoplasty-the-use-of-ophthalmic-viscoelastic-devices-in-hypotonic-eyes-that-had-undergone-glaucoma-filtering-surgeries
#17
Itaru Oyakawa, Takahiko Hayashi, Toshiki Shimizu, Naoko Kato
Purpose: Descemet's stripping automated endothelial keratoplasty (DSAEK) is more difficult in hypotonic eyes with filtering bleb, due to the difficulties in elevating the intraocular pressure (IOP). We report a new method that uses ophthalmic viscoelastic devices (OVDs) to achieve good graft adhesion. Case Presentation: We performed modified DSAEK surgery on 2 eyes of 2 patients, who had previously undergone a trabeculectomy. Both eyes had functioning filtering blebs; the IOP was lower than 10 mmHg without medication...
2018: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29410297/trends-in-corneal-transplantation-from-2001-to-2016-in-germany-a-report-of-the-dog-section-cornea-and-its-keratoplasty-registry
#18
Elias Flockerzi, Philip Maier, Daniel Böhringer, Helga Reinshagen, Friedrich Kruse, Claus Cursiefen, Thomas Reinhard, Gerd Geerling, Necip Torun, Berthold Seitz
PURPOSE: The purpose of this retrospective panel study was to provide an overview of absolute numbers and of trends in the types of and indications for corneal transplantation in Germany from 2001 to 2016. METHODS: A questionnaire about absolute numbers, types of transplantation, and indications was sent to 111 ophthalmologic departments in Germany, out of which 94 (85%) provided their data. RESULTS: Since the year 2001, the number of corneal transplantations has increased by 1...
April 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29403583/factors-influencing-graft-endothelial-cell-density-after-descemet-stripping-automated-endothelial-keratoplasty
#19
Mohammad Ali Javadi, Sepehr Feizi, Roya Jafari, Seyed Bagher Hosseini, Sharareh Safapour
Purpose: To determine the factors that influence the endothelial cell density (ECD) of donor grafts after Descemet stripping automated endothelial keratoplasty (DSAEK). Methods: This retrospective, interventional case series comprised 77 eyes of 64 patients who underwent DSAEK. Confocal microscopy was performed at the final follow-up examination to evaluate the endothelial cell count, cell morphology, and graft thickness. Univariate and multiple linear regression analyses were used to investigate recipient-, donor-, surgical-, and postoperative related variables capable of influencing graft endothelial cell counts after DSAEK...
January 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29392310/preoperative-aqueous-cytokine-levels-are-associated-with-endothelial-cell-loss-after-descemet-s-stripping-automated-endothelial-keratoplasty
#20
Hiroyuki Yazu, Takefumi Yamaguchi, Naohiko Aketa, Kazunari Higa, Terumasa Suzuki, Yukari Yagi-Yaguchi, Yoshiyuki Satake, Takayuki Abe, Kazuo Tsubota, Jun Shimazaki
Purpose: To evaluate the association between endothelial cell density (ECD) after Descemet's stripping automated endothelial keratoplasty (DSAEK) and preoperative cytokine levels in the aqueous humor (AqH). Methods: This prospective consecutive case series included 97 consecutive patients who underwent DSAEK (64 eyes) or cataract surgery (33 eyes). AqH samples were collected at the beginning of each surgery. The levels of cytokines (IL-1α, IL-1β, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13, IL-17A, IFN-α, IFN-γ, monocyte chemotactic protein [MCP]-1, E-selectin, P-selectin, and soluble intercellular adhesion molecule [sICAM]-1) in the AqH were measured by multiplex beads immunoassay...
February 1, 2018: Investigative Ophthalmology & Visual Science
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