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Descemet's stripping automated endothelial keratoplasty

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https://www.readbyqxmd.com/read/28440248/descemet-stripping-automated-endothelial-keratoplasty
#1
Namrata Sharma, Prafulla K Maharana, Shipra Singhi, Neelima Aron, Mukesh Patil
Endothelial keratoplasty is at present the gold standard for surgical treatment of corneal endothelial pathologies not associated with significant corneal scar. Tremendous progress has been made in recent years in improving the technology of endothelial keratoplasty techniques, such as descemet stripping automated endothelial keratoplasty (DSAEK) and descemet membrane endothelial keratoplasty. In this review, we discuss the current techniques and outcomes of DSAEK.
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28417337/descemet-stripping-automated-endothelial-keratoplasty-versus-descemet-membrane-endothelial-keratoplasty-a-meta-analysis
#2
REVIEW
Leru Zhu, Yi Zha, Jianqiu Cai, Yanling Zhang
PURPOSE: To evaluate the efficacy and safety of descemet stripping automated endothelial keratoplasty (DSAEK) compared with descemet membrane endothelial keratoplasty (DMEK). METHODS: Databases including PubMed, EMBASE, and Cochrane Library were searched to find studies that compared DSAEK and DMEK outcomes. Efficacy parameters were the postoperative best-corrected visual acuity (BCVA) and spherical equivalent (SE). Safety parameters were postoperative endothelial cell loss (ECL), air injection (rebubbling), graft failure, graft rejection, and high intraocular pressure (IOP)...
April 17, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28410361/rates-of-intraocular-pressure-elevation-and-use-of-topical-antihypertensive-medication-after-descemet-stripping-automated-endothelial-keratoplasty
#3
Mona Kaleem, Faisal Ridha, Zryan Shwani, Bonnielin Swenor, Jeffrey Goshe, Annapurna Singh
PURPOSE: To investigate intraocular pressure (IOP) elevation and medication augmentation after Descemet stripping automated endothelial keratoplasty (DSAEK) in those with and without glaucoma. METHODS: The records of 379 patients who underwent DSAEK at the Cleveland Clinic Foundation between January 2009 and 2014 were retrospectively reviewed. Postoperative IOP elevations were considered significant if IOP was ≥22 mm Hg on at least 1 follow-up visit or if it increased by ≥10 mm Hg from baseline...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28410357/donor-endothelial-cell-count-does-not-correlate-with-descemet-stripping-automated-endothelial-keratoplasty-transplant-survival-after-2-years-of-follow-up
#4
Ivan O Potapenko, Branka Samolov, Margareta Claesson Armitage, Berit Byström, Jesper Hjortdal
PURPOSE: To analyze the influence of low endothelial cell density (ECD) of donor cornea tissue, donor age, and sex on the transplant survival rate after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Graft ECD, age, and sex of donors used for DSAEK (n = 1789) during 7 years (2007-2014) in 4 Scandinavian hospitals were assessed for potential association with transplant survival at 2 years of follow-up using a Cox regression model correcting for confounding factors...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28399038/intraoperative-optical-coherence-tomography-assisted-descemet-stripping-automated-endothelial-keratoplasty-for-anterior-chamber-fibrous-ingrowth
#5
Tarek A Shazly, Lillian K To, Ian P Conner, Ladan Espandar
PURPOSE: Here, we present the first reported case of intraoperative optical coherence tomography (OCT)-assisted Descemet membrane stripping automated endothelial keratoplasty (DSAEK) in a patient with anterior segment fibrous ingrowth. METHODS: A 61-year-old woman with corneal edema and chronic angle-closure glaucoma secondary to fibrous ingrowth after 2 glaucoma shunt device implantations underwent dissection and removal of anterior chamber fibrous ingrowth and DSAEK...
April 10, 2017: Cornea
https://www.readbyqxmd.com/read/28381247/outcomes-of-descemet-stripping-automated-endothelial-keratoplasty-using-imported-donor-corneas
#6
Kaevalin Lekhanont, Kavin Vanikieti, Nutthida Nimvorapun, Varintorn Chuckpaiwong
BACKGROUND: The lack of development of local donor tissue acquisition in several regions of the world has resulted in the necessity of performing keratoplasty with imported donor corneas. The greatest concern about the use of donor corneas supplied by foreign eye banks is the effect of the increased donor death-to-operation time which inevitably occurs during the tissue recovery, tissue processing, and tissue transfer between the countries. The purpose of this study was to report the outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) using imported donor corneas...
April 5, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28317665/preparation-of-ultrathin-grafts-for-descemet-stripping-endothelial-keratoplasty-with-a-single-microkeratome%C3%A2-pass
#7
Vito Romano, Bernhard Steger, Jayavani Myneni, Mark Batterbury, Colin E Willoughby, Stephen B Kaye
We present a technique to achieve ultrathin Descemet-stripping automated endothelial keratoplasty (DSAEK). Using a simple method of controlling artificial anterior chamber pressure and drying the corneal surface, it was possible to thin the donor cornea at a rate of 11 μm a minute. When the donor cornea was between 500 μm and 510 μm, a single pass was made using a 350 μm microkeratome head followed by a peripheral dissection. The resulting mean graft thickness was 83.2 μm ± 14.9 (SD) (range 50 to 98 μm) with a mean peripheral graft edge thickness of 106...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28314955/outcome-of-descemet-stripping-automated-endothelial-keratoplasty-in-eyes-with-an-ahmed-glaucoma-valve
#8
Patrick J Chiam, Robert Cheeseman, Vivian W Ho, Vito Romano, Anshoo Choudhary, Mark Batterbury, Stephen B Kaye, Colin E Willoughby
PURPOSE: The purpose was to investigate the survival of Descemet stripping automated endothelial keratoplasty (DSAEK) in eyes with an Ahmed glaucoma valve (AGV). METHODS: The study had a retrospective case-series of patients with an AGV in the anterior chamber undergoing a DSAEK. Included in the analysis were graft size, number of previous operations, post-operative glaucoma medications, post-operative intraocular pressure (IOP) control, graft size and donor factors (age, endothelial cell density, and post-mortem time)...
March 17, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28260451/descemet-stripping-automated-endothelial-keratoplasty-our-experience-at-king-hussein-medical-center
#9
Amal Al-Thawabi, Wafa Asfour, Mousa Al-Madani
OBJECTIVES: In this study, we report our experience at King Hussein Medical Center with Descemet stripping automated endothelial keratoplasty. MATERIALS AND METHODS: This study was conducted at King Hussein Medical Center of the Royal Medical Services during the period between January 2015 and January 2016. Patients who underwent Descemet stripping automated endothelial keratoplasty were enrolled in the study. We performed a comprehensive overview of the advantages of the surgery and analyzed the donor tissue selection criteria, indications, detailed surgical techniques of the procedure, and surgical outcomes...
February 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28259779/in-vivo-characteristics-of-corneal-endothelium-descemet-s-membrane-complex-for-the-diagnosis-of-corneal-graft-rejection
#10
Mohamed Abou Shousha, Sonia H Yoo, Mohamed S Sayed, Sean Edelstein, Matthew Council, Ravi S Shah, Joshua Abernathy, Zachary Schmitz, Patrick Stuart, Rocio Bentivegna, Maria P Fernandez, Christopher Smith, Xiaotang Yin, George J Harocopos, Sander R Dubovy, William J Feuer, Jianhua Wang, Victor L Perez
PURPOSE: To evaluate the utility of Endothelial/Descemet's membrane complex (En/DM) characteristics in diagnosing corneal graft rejection. DESIGN: Diagnostic reliability study. METHODS: 139 eyes (96 corneal grafts post penetrating keratoplasty or Descemet's stripping automated endothelial keratoplasty: 40 clear, 23 actively rejecting, 24 rejected and 9 non-immunological failed grafts, along with 43 age-matched control eyes) were imaged using high-definition optical coherence tomography...
March 1, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28237153/current-indications-and-surgical-approaches-to-corneal-transplants-at-the-university-of-toronto-a-clinical-pathological-study
#11
Ryan Le, Narain Yucel, Shireen Khattak, Yeni H Yucel, Gerald J Prud'homme, Neeru Gupta
OBJECTIVE: To determine the most common reasons and surgical approaches for corneal graft surgery at the Kensington Eye Institute (KEI), University of Toronto. DESIGN: Retrospective cross-sectional study. PARTICIPANTS: A total of 229 consecutive corneal transplants performed at the KEI. METHODS: Demographic, clinical, and pathological data on all 2012 and 2013 corneal transplants were collected. RESULTS: The mean age for corneal transplants was 65 ± 16 years; 39% were full-thickness penetrating keratoplasties (PK) and 61% were partial-thickness...
February 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28181931/avoiding-complications-associated-with-preloaded-ultrathin-descemet-stripping-automated-endothelial-keratoplasty
#12
Mohit Parekh, Alessandro Ruzza, Bernhard Steger, Colin E Willoughby, Stefano Ferrari, Diego Ponzin, Stephen B Kaye, Vito Romano
No abstract text is available yet for this article.
February 8, 2017: Cornea
https://www.readbyqxmd.com/read/28160608/is-there-evidence-for-a-surgeon-learning-curve-for-endothelial-keratoplasty-in-australia
#13
Miriam C Keane, Richard Ad Mills, Douglas J Coster, Keryn A Williams
IMPORTANCE: Expected outcomes from endokeratoplasty may vary with surgeon experience. BACKGROUND: It was explored whether a surgeon learning curve exists for Descemet stripping endothelial keratoplasties (manual or automated) performed in Australia. DESIGN: This is a prospective cohort study, with various clinical settings. PARTICIPANTS: There were 2139 recipients of 2615 endothelial grafts, registered by 85 surgeons between January 2006 and December 2013...
February 4, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28129297/toxic-anterior-segment-syndrome-inadvertent-administration-of-intracameral-lidocaine-1-and-phenylephrine-2-5-preserved-with-10-benzalkonium-chloride-during-cataract-surgery
#14
Brett P Bielory, Ayesha Shariff, Rehan M Hussain, Jose Antonio Bermudez-Magner, Sander R Dubovy, Kendall E Donaldson
PURPOSE: To report 3 patients with corneal decompensation and anterior uveitis within 24 hours of cataract surgery from a single ambulatory surgery center using intracameral lidocaine HCl 1% and phenylephrine 2.5% inadvertently preserved with 10% benzalkonium chloride. METHODS: This case series describes 3 patients who underwent traditional cataract extraction with a significant decrease in visual acuity in the immediate postoperative period resulting in secondary surgical intervention for corneal decompensation in 2 patients...
May 2017: Cornea
https://www.readbyqxmd.com/read/28079689/scanning-electron-microscope-analysis-of-stromal-surface-regularity-in-dsaek-using-manual-or-automated-microkeratomes-or-dmek
#15
Alberto Villarrubia, Enrique García, Antonio Cano-Ortiz, Alberto Membrillo, Antoni Sabala, Javier Celis, Antoni Salvador, Jorge Solana, Alexandra Arango, Irene Sassot
PURPOSE: To analyze differences in the stromal bed according to the method used to obtain the disc for endothelial transplant with 1) an automated microkeratome for Descemet stripping automated endothelial keratoplasty (DSAEK), 2) homogeneous dissection of Descemet membrane (Descemet membrane endothelial keratoplasty [DMEK]), or 3) a manual microkeratome used for DSAEK. METHODS: We analyzed the stromal bed of 25 consecutive corneas used for endothelial transplantation, divided into 3 groups: 1) 11 samples cut with an automated microkeratome, 2) 5 samples used for DMEK, 3) 9 samples cut with a manual microkeratome...
May 2017: Cornea
https://www.readbyqxmd.com/read/28079683/factors-associated-with-graft-detachment-after-primary-descemet-stripping-automated-endothelial-keratoplasty
#16
Yoav Nahum, Pia Leon, Michael Mimouni, Massimo Busin
PURPOSE: To identify risk factors associated with postoperative graft detachment after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: In this retrospective institutional cohort study, the study group included all consecutive eyes that underwent primary DSAEK between January 2005 and October 2015 at Villa Serena-Villa Igea private hospitals (Forlì, Italy) and developed postoperative graft detachment (n = 45). The control group included all eyes that underwent primary DSAEK during the same period and did not develop graft detachment (n = 1167)...
March 2017: Cornea
https://www.readbyqxmd.com/read/28069281/-effect-of-donor-graft-characteristics-on-clinical-outcomes-in-descemet-stripping-automated-endothelial-keratoplasty-dsaek
#17
G Ho Wang Yin, M Sampo, S Soare, L Hoffart
INTRODUCTION: The purpose of our study was to evaluate the progression of lamellar corneal grafts after endothelial keratoplasty by Descemet stripping automated endothelial keratoplasty (DSAEK) and the effect of their characteristics on the clinical and functional results. MATERIALS AND METHODS: This was a prospective study in which 74 patients who had undergone endothelial keratoplasty by DSAEK were included. The corneal grafts were obtained from a French tissue bank and were delivered in a preservation medium containing a deturgescent agent (Corneajet(®) or Stemalpha 3(®))...
January 6, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28017678/deep-anterior-lamellar-keratoplasty-after-descemet-stripping-automated-endothelial-keratoplasty
#18
Shay Gutfreund, Pia Leon, Shmuel Graffi, Massimo Busin
PURPOSE: To report the indications and long-term outcomes of deep anterior lamellar keratoplasty (DALK) performed after Descemet stripping automated endothelial keratoplasty (DSAEK) in cases of visually significant stromal opacities. DESIGN: Retrospective, interventional, consecutive case series. METHODS: Setting: Private hospital. STUDY POPULATION: Thirteen eyes that underwent DALK after DSAEK at our institution. Indications for DALK after DSAEK included both stromal opacities persisting after DSAEK and stromal opacities occurring secondarily in post-DSAEK corneas...
March 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27994806/descemet-stripping-automated-endothelial-keratoplasty-in-fuchs-endothelial-dystrophy-versus-pseudophakic-bullous-keratopathy
#19
Mohammad Ali Javadi, Sepehr Feizi, Roya Jafari, Firooz Mirbabaee, Vahid Ownagh
PURPOSE: To compare clinical and confocal scan outcomes after Descemet stripping automated endothelial keratoplasty (DSAEK) performed for Fuchs' endothelial dystrophy (FED) versus pseudophakic bullous keratopathy (PBK). METHODS: This retrospective comparative study included 47 consecutive eyes of 39 patients with the diagnosis of FED (n = 29, group 1) or PBK (n = 18, group 2) that underwent DSAEK. Clinical outcomes were compared between the study groups. At the final follow-up examination, confocal microscopy was used to measure and compare central corneal and graft thickness as well as endothelial cell density and morphology between the two groups...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27986384/cystoid-macular-edema-after-descemet-s-stripping-automated-endothelial-keratoplasty
#20
Koji Kitazawa, Kanae Kayukawa, Koichi Wakimasu, Isao Yokota, Tsutomu Inatomi, Osamu Hieda, Kazuhiko Mori, Chie Sotozono, Shigeru Kinoshita
No abstract text is available yet for this article.
December 13, 2016: Ophthalmology
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