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https://www.readbyqxmd.com/read/27744612/follow-up-of-patients-with-adrenal-incidentaloma-in-accordance-with-the-european-society-of-endocrinology-guidelines-could-we-be-safe
#1
V Morelli, A Scillitani, M Arosio, I Chiodini
Recently, the European Society of Endocrinology (ESE) published new guidelines on the management of adrenal incidentalomas. At the same time Lopez and coworkers published on the Annals of Internal Medicine an important study showing that even patients with non-functioning adrenal tumors have an increased risk of incident diabetes. In consideration of previous data and of the results of the study of Lopez and coworkers, some points emerge from the ESE Guidelines that deserve attention. Firstly, it must be observed that the term "autonomous cortisol secretion," introduced by the ESE Panel in the place of the commonly used "subclinical hypercortisolism," seems questionable, since the guidelines do not suggest determining the adrenocorticotroph hormone levels that could give the certain proof of a truly autonomous cortisol secretion...
October 15, 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27645051/neuroendocrine-tumors-moving-from-the-land-of-small-tumors-to-an-expanding-universe
#2
Marianne Pavel
Extract: During my medical studies at the Georg August University of Göttingen in the late 1980's, I was truly inspired early by my mentor and University teacher Werner Creutzfeldt to begin working in the field of neuroendocrine Tumors (NET). Werner Creutzfeldt was a leader of excellence in the field of gastrointestinal endocrinology, neuroendocrine tumors and the entero-insulinar axis/incretin system in Germany. At this time, treatment of NET, i.e. pancreatic NET was reduced to the use of chemotherapeutics like streptozotocin and others with less success...
September 19, 2016: Endocrine-related Cancer
https://www.readbyqxmd.com/read/27628103/significance-of-frailty-for-predicting-adverse-clinical-outcomes-in-different-patient-groups-with-specific-medical-conditions
#3
Martin Ritt, Karl-Günter Gaßmann, Cornel Christian Sieber
Frailty is a major health burden in an aging society. It constitutes a clinical state of reduced physiological reserves that is associated with a diminished ability to withstand internal and external stressors. Frail patients have an increased risk for adverse clinical outcomes, such as mortality, readmission to hospital, institutionalization and falls. Of further clinical interest, frailty might be at least in part reversible in some patients and subject to preventive strategies. In daily clinical practice older patients with a complex health status, who are mostly frail or at least at risk of developing frailty, are frequently cared for by geriatricians...
October 2016: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/27604159/perceptions-of-medical-doctors-on-bisphosphonate-related-osteonecrosis-of-the-jaw
#4
Jin-Woo Kim, Su-Ra Jeong, Sun-Jong Kim, YeonSoo Kim
BACKGROUND: This study aimed to investigate medical doctors' awareness of bisphosphonate-related osteonecrosis of the jaw (BRONJ) and the status of dental referrals. METHODS: Self-administered questionnaires were distributed to medical doctors practicing internal medicine, family medicine, and orthopedics at the 6 tertiary medical centers located in Seoul, Korea. The survey consisted of 22 questions regarding the general characteristics, bisphosphonate therapy, awareness of BRONJ, and implementation of dental referrals...
September 7, 2016: BMC Oral Health
https://www.readbyqxmd.com/read/27569712/frailty-and-sarcopenia-as-predictors-of-adverse-health-outcomes-in-persons-with-diabetes-mellitus
#5
Anthony Liccini, Theodore K Malmstrom
OBJECTIVES: Diabetes mellitus is associated with premature aging, and chronic diabetes is associated with significant physical and cognitive complications. We aimed to examine frailty and sarcopenia rates and 6-month health outcomes in a clinic-based sample of patients with diabetes. DESIGN: This study was an observational study. Participants were recruited from June 2014 to August 2014, and follow-up was conducted 6 months after day of screening. SETTING: Participants were recruited at outpatient endocrinology, geriatric, and internal medicine clinics affiliated with Saint Louis University in St...
September 1, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27569120/low-adoption-of-weight-loss-medications-a-comparison-of-prescribing-patterns-of-antiobesity-pharmacotherapies-and-sglt2s
#6
Catherine E Thomas, Elizabeth A Mauer, Alpana P Shukla, Samrat Rathi, Louis J Aronne
OBJECTIVE: To characterize the adoption of antiobesity pharmacotherapies, as compared with that of the newest antidiabetes pharmacotherapy, subtype 2 sodium-glucose transport protein inhibitors (SGLT2s), among prescribers in the United States. METHODS: A retrospective analysis of 2012 to 2015 data extracted from the IMS Health National Prescription Audit™ and Xponent™ assessed adoption rates of antiobesity pharmacotherapies and SGLT2s. RESULTS: The number of dispensed antidiabetes prescriptions was 15 times the number of dispensed antiobesity prescriptions...
September 2016: Obesity
https://www.readbyqxmd.com/read/27493908/comparing-nurses-knowledge-retention-following-electronic-continuous-education-and-educational-booklet-a-controlled-trial-study
#7
Mahmud Badiei, Mitra Gharib, Mitra Zolfaghari, Rita Mojtahedzadeh
BACKGROUND: Training methods that enhance nurses' learning and retention will increase the quality of patient care. This study aimed to compare the effectiveness of electronic learning and educational booklet on the nurses' retention of diabetes updates. METHODS: In this controlled trial study, convenience sampling was used to select 123 nurses from the endocrinology and internal medicine wards of three hospitals affiliated to Tehran University of Medical Sciences (Tehran, Iran)...
2016: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/27466235/characteristics-of-patients-with-type-2-diabetes-mellitus-newly-treated-with-glp-1-receptor-agonists-chadig-study-a-cross-sectional-multicentre-study-in-spain
#8
Ignacio Conget, Dídac Mauricio, Rafael Ortega, Bruno Detournay
OBJECTIVE: Several glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1Ra) have been made recently available in Spain for type 2 diabetes mellitus (DM2) treatment. There are no published data on the clinical and sociodemographic profile of patients initiating treatment with GLP-1Ra in Spain. Our objective was to understand these patients' characteristics in a real-world clinical practice setting. DESIGN: Cross-sectional observational study. SETTING: Spanish specialist outpatient clinics...
2016: BMJ Open
https://www.readbyqxmd.com/read/27413444/effectiveness-of-an-interprofessional-and-multidisciplinary-musculoskeletal-training-program
#9
Michael J Battistone, Andrea M Barker, Marissa P Grotzke, J Peter Beck, Jeffery T Berdan, Jorie M Butler, Caroline K Milne, Tim Huhtala, Grant W Cannon
BACKGROUND: Musculoskeletal (MSK) problems are common, and a recent US Bone and Joint Initiative calls for new models of education and professional collaboration. Evidence of feasibility and acceptability of innovative methods are needed. OBJECTIVE: We assessed if an experimental immersion interdisciplinary MSK curriculum would be acceptable to residents from different specialties, be feasible within existing rotations, and be effective in strengthening clinical skills...
July 2016: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/27355225/the-management-of-graves-disease-in-new-zealand-2014
#10
Stephanie C Cox, Jade Au Tamatea, John V Conaglen, Marianne S Elston
BACKGROUND: Treatment options for Graves' disease (GD), namely anti-thyroid drugs (ATD), surgery or radioiodine (RAI), have not changed over the past two decades. There is no 'gold-standard' treatment for GD. AIMS: To assess whether the management of GD in New Zealand has changed since the previous 1991 New Zealand survey and compare current management with that of contemporary international studies. METHODS: We conducted an online survey of New Zealand physicians currently practising internal medicine, diabetes and/or endocrinology, using the cases and questions from the original European and 1991 New Zealand studies...
June 10, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27343020/adult-onset-hypogonadism
#11
REVIEW
Mohit Khera, Gregory A Broderick, Culley C Carson, Adrian S Dobs, Martha M Faraday, Irwin Goldstein, Lawrence S Hakim, Wayne J G Hellstrom, Ravi Kacker, Tobias S Köhler, Jesse N Mills, Martin Miner, Hossein Sadeghi-Nejad, Allen D Seftel, Ira D Sharlip, Stephen J Winters, Arthur L Burnett
In August 2015, an expert colloquium commissioned by the Sexual Medicine Society of North America (SMSNA) convened in Washington, DC, to discuss the common clinical scenario of men who present with low testosterone (T) and associated signs and symptoms accompanied by low or normal gonadotropin levels. This syndrome is not classical primary (testicular failure) or secondary (pituitary or hypothalamic failure) hypogonadism because it may have elements of both presentations. The panel designated this syndrome adult-onset hypogonadism (AOH) because it occurs commonly in middle-age and older men...
July 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27333724/nocturnal-hypoglycemia-the-main-indication-for-insulin-pump-therapy-in-adulthood
#12
Maja Baretić, Ivana Kraljević, Ivana Pavlić Renar
The aim was to determine which adult type 1 diabetic patient receiving multiple daily injection therapy is the most appropriate candidate for insulin pump therapy, while taking into consideration limited insulin pump affordability in Croatia. A total of 145 type 1 diabetic patients (52% diagnosed in adult age) were monitored at the Department of Endocrinology, Clinical Department of Internal Medicine, Zagreb University Hospital Center from 2009 to 2014. Twenty-one patients started insulin pump therapy in adulthood (seven men and 14 women, median age 27)...
March 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/27313122/fundamental-concepts-regarding-testosterone-deficiency-and-treatment-international-expert-consensus-resolutions
#13
Abraham Morgentaler, Michael Zitzmann, Abdulmaged M Traish, Anthony W Fox, T Hugh Jones, Mario Maggi, Stefan Arver, Antonio Aversa, Juliana C N Chan, Adrian S Dobs, Geoffrey I Hackett, Wayne J Hellstrom, Peter Lim, Bruno Lunenfeld, George Mskhalaya, Claude C Schulman, Luiz O Torres
To address widespread concerns regarding the medical condition of testosterone (T) deficiency (TD) (male hypogonadism) and its treatment with T therapy, an international expert consensus conference was convened in Prague, Czech Republic, on October 1, 2015. Experts included a broad range of medical specialties including urology, endocrinology, diabetology, internal medicine, and basic science research. A representative from the European Medicines Agency participated in a nonvoting capacity. Nine resolutions were debated, with unanimous approval: (1) TD is a well-established, clinically significant medical condition that negatively affects male sexuality, reproduction, general health, and quality of life; (2) symptoms and signs of TD occur as a result of low levels of T and may benefit from treatment regardless of whether there is an identified underlying etiology; (3) TD is a global public health concern; (4) T therapy for men with TD is effective, rational, and evidence based; (5) there is no T concentration threshold that reliably distinguishes those who will respond to treatment from those who will not; (6) there is no scientific basis for any age-specific recommendations against the use of T therapy in men; (7) the evidence does not support increased risks of cardiovascular events with T therapy; (8) the evidence does not support increased risk of prostate cancer with T therapy; and (9) the evidence supports a major research initiative to explore possible benefits of T therapy for cardiometabolic disease, including diabetes...
July 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27233786/-the-choosing-wisely-initiative-of-the-german-society-of-internal-medicine-recommendations-of-the-german-society-for-endocrinology-and-the-german-society-for-geriatrics
#14
J Feldkamp, M Schott, M Gogol, M Quinkler, M Blüher, S Diederich, M Reincke
POSITIVE RECOMMENDATIONS: A. After osteoporotic fractures in the elderly, as a rule specific antiosteoporotic therapy should be initiated. a. Osteoporosis as a disease of the elderly should be diagnosed and treated (recommendation of the German Society for Geriatrics). B. All patients with diabetes mellitus should complete a specific diabetes training program when antidiabetic drug medication is initiated. C. In Germany, all pregnant women should be advised to undertake iodine supplementation...
June 2016: Der Internist
https://www.readbyqxmd.com/read/27206936/provider-understanding-of-the-2013-acc-aha-cholesterol-guideline
#15
Salim S Virani, Yashashwi Pokharel, Lynne Steinberg, Winston Chan, Julia M Akeroyd, Saqib Ali Gowani, Ankur Kalra, Venkateshwar Polsani, Michael D Miedema, Peter H Jones, Vijay Nambi, Laura A Petersen, Christie M Ballantyne
BACKGROUND: Providers' understanding of the 2013 American College of Cardiology (ACC)/American Heart Association (AHA) cholesterol guideline in clinical practice is not known. METHODS: We designed a questionnaire, which was administered to internal medicine, family practice, cardiology, and endocrinology providers at 21 venues across the United States. We compared responses between providers in training or practice and between specialists (cardiology and endocrinology) and nonspecialists (internal medicine and family practice)...
May 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/26996646/teaching-internal-medicine-in-the-community
#16
Sophia Eilat-Tsanani, M Weingarten, M Ben-Ami, Mordechai Dayan, H Tabenkin
BACKGROUND: Teaching Internal Medicine is mainly hospital-based. Chronic diseases are treated mostly in community-based ambulatory care. This study describes our experience during the first year of teaching Internal Medicine in the community, with a focus on chronic disease management. METHODS: This was an observational study describing the content of clinical exposure and the feedback from students after a two-week clerkship in community health centers. RESULTS: Over a period of three months, 54 students spent two weeks in health centers singly or in pairs...
September 2015: Education for Health: Change in Training & Practice
https://www.readbyqxmd.com/read/26944463/endocrinologic-control-of-men-s-sexual-desire-and-arousal-erection
#17
REVIEW
Giovanni Corona, Andrea M Isidori, Antonio Aversa, Arthur L Burnett, Mario Maggi
INTRODUCTION: Several hormones and neurotransmitters orchestrate men's sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases. AIM: To provide an overview and recommendations regarding endocrinologic control of sexual desire and arousal and erection and their disturbances. METHODS: Medical literature was reviewed by the subcommittee of the International Consultation of Sexual Medicine, followed by extensive internal discussion, and then public presentation and discussion with other experts...
March 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/26927534/spanish-consensus-on-the-risks-and-detection-of-antipsychotic-drug-related-hyperprolactinaemia
#18
Ángel L Montejo, Celso Arango, Miguel Bernardo, José L Carrasco, Benedicto Crespo-Facorro, Juan J Cruz, Javier Del Pino, Miguel A García Escudero, Clemente García Rizo, Ana González-Pinto, Ana I Hernández, Manuel Martín Carrasco, Fermin Mayoral Cleries, Jaqueline Mayoral van Son, M Teresa Mories, Isabella Pachiarotti, Salvador Ros, Eduard Vieta
INTRODUCTION: Iatrogenic hyperprolactinaemia (IHPRL) has been more frequently related to some antipsychotic drugs that provoke an intense blockade of dopamine D2 receptors. There is a wide variation in clinical practice, and perhaps some more awareness between clinicians is needed. Due to the high frequency of chronic treatment in severe mental patients, careful attention is recommended on the physical risk. IHPRL symptoms could be underestimated without routine examination. METHODOLOGY: An intense scientific literature search was performed in order to draw up a multidisciplinary consensus, including different specialists of psychiatry, endocrinology, oncology and internal medicine, and looking for a consensus about clinical risk and detection of IHPRL following evidence-based medicine criteria levels (EBM I- IV)...
July 2016: Revista de Psiquiatrí́a y Salud Mental
https://www.readbyqxmd.com/read/26719499/exercise-prescription-for-patients-with-type-2-diabetes-a-synthesis-of-international-recommendations-narrative-review
#19
Romeu Mendes, Nelson Sousa, António Almeida, Paulo Subtil, Fernando Guedes-Marques, Victor Machado Reis, José Luís Themudo-Barata
BACKGROUND: Physical activity is a cornerstone of type 2 diabetes treatment and control. AIM: We analysed and synthesised the guidelines and recommendations issued by scientific organisations, regarding exercise prescription for patients with type 2 diabetes. METHOD: A systematic bibliographic search in Pubmed, Web of Science and Scopus databases was conducted. Clinical guidelines from major international scientific organisations in the field of diabetology, endocrinology, cardiology, public health and sports medicine were also considered...
December 30, 2015: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/26693445/endocrinology-during-internal-medicine-residency-the-dark-side-of-the-moon
#20
Krishnarpan Chatterjee, Chetana Sen
No abstract text is available yet for this article.
November 2015: Indian Journal of Endocrinology and Metabolism
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