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https://www.readbyqxmd.com/read/29316871/listeria-monocytogenes-sepsis-in-the-nursing-home-community-a-case-report-and-short-review-of-the-literature
#1
Griet Buyck, Veronique Devriendt, Anne-Marie Van den Abeele, Christian Bachmann
Objective and importance Listeria monocytogenes is a rare foodborne pathogen, causing both outbreaks and sporadic infections. Severe, systemic infections are more prevalent in at-risk populations, such as pregnant women, but occur mostly in older people and immunocompromised individuals. In this case report, we describe the presentation, diagnosis, and treatment of Listeria monocytogenes sepsis in an older patient, and we briefly review the literature about listeriosis and the importance of safe food practices...
January 9, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29315631/molecular-epidemiology-and-genotype-distributions-of-noroviruses-and-sapoviruses-in-thailand-2000-2016-a-review
#2
REVIEW
Kattareeya Kumthip, Pattara Khamrin, Niwat Maneekarn
Norovirus (NoV) and sapovirus (SaV) infections remain public health problems in Thailand, particularly, causing an acute gastroenteritis in people of all age groups. This review summarizes the epidemiology and genotype distribution of NoV and SaV in Thailand during the period of 2000 to 2016. The overall prevalence of NoV infection in patients with acute gastroenteritis of all age groups ranged from 0.09 to 44.7% while those of SaV were 0.0 to 15.0%. The majority of NoV genogroup detected was NoV GII with a small proportion of NoV GI...
January 5, 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29299895/community-acquired-escherichia-coli-enteritis-in-korean-children-the-clinical-application-of-a-stool-polymerase-chain-reaction-assay
#3
Youie Kim, Hyo Jin Kim, Sooyeon Lim, Kil Seong Bae, Seung Beom Han, Dae Chul Jeong, Jin Han Kang, Gook Jae Shin, Gun Dong Lee, Yeon Joon Park
BACKGROUND: Although Escherichia coli is a common cause of bacterial enteritis in Korea, reports on community-acquired E. coli enteritis in Korean children are scarce. This study aimed to determine the clinical characteristics and pathotype distribution of community-acquired E. coli enteritis diagnosed by a multiplex polymerase chain reaction (PCR) assay in Korean children. MATERIALS AND METHODS: The medical records of children aged 18 years or less who were diagnosed with acute gastroenteritis by the attending physician between 2013 and 2016 were retrospectively reviewed...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29290097/challenges-in-developing-mucosal-vaccine-and-antibodies-against-infectious-diarrhea-in-children
#4
REVIEW
Daisuke Tokuhara
Infectious diarrhea in children can be life-threatening and imposes a large economic burden on healthcare systems, therefore more effective prophylactic and therapeutic drugs are needed urgently. Because most of the pathogens responsible for childhood diarrhea infect the gastrointestinal mucosa, providing protective immunity at the mucosal surface is an ideal way to control pathogen invasion and toxic activity. Mucosal (e.g., oral, nasal) vaccines are superior to systemic (subcutaneous or intramuscular) vaccination for conferring both mucosal and systemic pathogen-specific immune responses...
December 31, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29276769/low-incidence-of-opportunistic-infections-in-lupus-patients-treated-with-cyclophosphamide-and-steroids-in-a-tertiary-care-setting
#5
Shubhasree Banerjee, Ann Biehl, Maryam Ghaderi-Yeganeh, Zerai Manna, Sarfaraz Hasni
Background: Infection is common cause of morbidity and mortality in systemic lupus erythematosus (SLE). Our objective was to determine incidence and types of infections, particularly opportunistic infections, in SLE patients receiving cyclophosphamide, and to identify contribution of variables like demographics, steroid, other immunosuppressives, white blood cell and absolute neutrophil count to infection risk. Patients and Methods: We did retrospective chart review of SLE patients in our institute over last 10 years, who received minimum six cyclophosphamide infusions...
March 2017: Medical Research Archives
https://www.readbyqxmd.com/read/29276700/an-updated-view-on-the-rck-invasin-of-salmonella-still-much-to-discover
#6
REVIEW
Julien Mambu, Isabelle Virlogeux-Payant, Sébastien Holbert, Olivier Grépinet, Philippe Velge, Agnès Wiedemann
Salmonella is a facultative intracellular Gram-negative bacterium, responsible for a wide range of food- and water-borne diseases ranging from gastroenteritis to typhoid fever depending on hosts and serotypes. Salmonella thus represents a major threat to public health. A key step in Salmonella pathogenesis is the invasion of phagocytic and non-phagocytic host cells. To trigger its own internalization into non-phagocytic cells, Salmonella has developed different mechanisms, involving several invasion factors...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29272955/laribacter-hongkongensis-clinical-presentation-epidemiology-and-treatment-a-review-of-the-literature-and-report-of-the-first-case-in-denmark
#7
Anne Line Engsbro, Karen Leth Nielsen, Mads Hornum, Leif Percival Andersen
BACKGROUND: Laribacter hongkongensis is an emerging pathogen related to gastroenteritis that can cause invasive and even fatal disease. The aim of this review is to describe the clinical presentation, epidemiology, treatment options and implications for the clinical microbiology laboratory. METHODS: We searched Pubmed using the term Laribacter hongkongensis with limitations human and language English, and identified 35 publications with eight reports on human cases...
December 22, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29231855/differences-of-rotavirus-vaccine-effectiveness-by-country-likely-causes-and-contributing-factors
#8
REVIEW
Ulrich Desselberger
Rotaviruses are a major cause of acute gastroenteritis in infants and young children worldwide and in many other mammalian and avian host species. Since 2006, two live-attenuated rotavirus vaccines, Rotarix® and RotaTeq®, have been licensed in >100 countries and are applied as part of extended program of vaccination (EPI) schemes of childhood vaccinations. Whereas the vaccines have been highly effective in high-income countries, they were shown to be considerably less potent in low- and middle-income countries...
December 12, 2017: Pathogens
https://www.readbyqxmd.com/read/29216670/-systematic-review-of-the-burden-of-campylobacter-associated-disease
#9
Julia Lackner, Daniela Schlichting, Christine Müller-Graf, Matthias Greiner
Bacteria of the genus Campylobacter spp. are one of the most common causes of gastroenteritis and can lead to serious sequelae. Several studies have estimated the disease burden of Campylobacter spp. with the quantitative metric of disability-adjusted life years (DALY). The aim of this systematic review is to give an overview of the information available about different countries and periods for which DALYs were calculated and how the different results are comparable. One of the most important transmission pathways for Campylobacter spp...
December 7, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29204334/norovirus-disease-in-older-adults-living-in-long-term-care-facilities-strategies-for-management
#10
Yingxi Chen, Aron J Hall, Martyn D Kirk
Purpose of Review: Noroviruses are the most common cause of gastroenteritis outbreaks in long-term care facility (LTCFs). This review summarizes the most up-to-date knowledge on norovirus infection in LTCFs with the aim of identifying potential strategies for management. Recent Findings: LTCF residents are at greater risk of norovirus infection. Early identification of norovirus infection and prompt initiation of appropriate supportive therapy are required to reduce morbidity and mortality...
2017: Current Geriatrics Reports
https://www.readbyqxmd.com/read/29197889/acute-necrotising-encephalopathy-of-childhood-a-review-of-two-cases
#11
S C L Ong, A H Nur Azidawati, Y H Liew, S Anita
Acute necrotising encephalopathy of childhood (ANEC) is an uncommon disease with characteristic clinical and imaging findings. We present two cases of ANEC secondary to Respiratory Syncytial Virus (RSV) and mycoplasma infections. An eight-month-old boy presented with features of gastroenteritis but soon developed multiple episodes of seizures. Blood and CSF cultures were negative but nasopharyngeal aspirate immunofluorescence was positive for RSV. A nine-year-old girl presented with abnormal behaviour following two days of prodromal symptoms...
October 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/29189589/pediatric-emergency-research-canada-origins-and-evolution
#12
Liza Bialy, Amy Plint, Roger Zemek, David Johnson, Terry Klassen, Martin Osmond, Stephen Freedman
OBJECTIVE: The objective of the study was to describe the origins, growth, and progress of a national research network in pediatric emergency medicine. METHODS: The success of Pediatric Emergency Research Canada (PERC) is described in terms of advancing the pediatric emergency medicine agenda, grant funding, peer-reviewed publications, mentoring new investigators, and global collaborations. RESULTS: Since 1995, clinicians and investigators within PERC have grown the network to 15 active tertiary pediatric emergency medicine sites across Canada...
November 20, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29173644/seafood-pathogens-and-information-on-antimicrobial-resistance-a-review
#13
REVIEW
S Elbashir, S Parveen, J Schwarz, T Rippen, M Jahncke, A DePaola
Seafood-borne diseases are a major public health hazard in the United States and worldwide. Per capita, seafood consumption has increased globally during recent decades. Seafood importation and domestic aquaculture farming has also increased. Moreover, several recent outbreaks of human gastroenteritis have been linked to the consumption of contaminated seafood. Investigation of seafood-borne illnesses caused by norovirus, and Vibrio, and other bacteria and viruses require a concrete knowledge about the pathogenicity and virulence properties of the etiologic agents...
April 2018: Food Microbiology
https://www.readbyqxmd.com/read/29159172/examining-the-link-between-biofilm-formation-and-the-ability-of-pathogenic-salmonella-strains-to-colonize-multiple-host-species
#14
REVIEW
Keith D MacKenzie, Melissa B Palmer, Wolfgang L Köster, Aaron P White
Salmonella are important pathogens worldwide and a predominant number of human infections are zoonotic in nature. The ability of strains to form biofilms, which is a multicellular behavior characterized by the aggregation of cells, is predicted to be a conserved strategy for increased persistence and survival. It may also contribute to the increasing number of infections caused by ingestion of contaminated fruits and vegetables. There is a correlation between biofilm formation and the ability of strains to colonize and replicate within the intestines of multiple host species...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29149805/observational-cohort-study-safety-outcomes-in-children-using-proton-pump-inhibitors-or-histamine-2-receptor-antagonists
#15
Eline Houben, Saga Johansson, Péter Nagy, Fernie J A Penning-van Beest, Ernst J Kuipers, Ron M C Herings
OBJECTIVE: Acid suppression with histamine-2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs) is recommended for children with persistent gastroesophageal reflux disease symptoms. In this retrospective, observational postauthorization study, we aimed to assess and compare safety outcomes in pediatric first-time users of esomeprazole, other PPIs or H2RAs. METHODS: Data on children (aged 0-18 years) first dispensed esomeprazole, other PPIs or H2RAs between September 2008 and August 2011 was obtained from the Dutch PHARMO Database Network...
November 24, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29143685/available-studies-fail-to-provide-strong-evidence-of-increased-risk-of-diarrhea-mortality-due-to-measles-in-the-period-4-26%C3%A2-weeks-after-measles-rash-onset
#16
Bianca D Jackson, Robert E Black
BACKGROUND: Measles vaccination effectiveness studies showed dramatic decreases in all-cause mortality in excess of what would be expected from the prevention of measles disease alone. This invited speculation that measles infection may increase the risk of diarrhea morbidity and mortality subsequent to the acute phase of the disease. The aim of the present systematic review is to summarize the existing evidence in the publically available literature pertaining to the putative causal link between measles and diarrhea in the period 4-26 weeks following measles rash onset...
November 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29135827/norovirus-and-rotavirus-disease-severity-in-children-systematic-review-and-meta-analysis
#17
Margarita Riera-Montes, Miguel O'Ryan, Thomas Verstraeten
BACKGROUND: Rotaviruses (RV) and Noroviruses (NoV) are the most common causes of severe acute gastroenteritis (AGE) in children. It is generally accepted that RV causes severe AGE in a higher proportion of cases compared with NoV. To our knowledge, there are no systematic reviews and meta-analyses comparing the severity of NoV and RV disease. METHODS: We searched MEDLINE for studies reporting data for NoV and RV medically-attended disease severity in children. We included studies where all children had been tested for both NoV (RT-PCR) and RV (ELISA or RT-PCR) and that reported disease severity using the Vesikari or modified Vesikari score, or provided clinical information on severity...
November 11, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29126448/the-epidemiology-of-norovirus-in-the-middle-east-and-north-africa-mena-region-a-systematic-review
#18
REVIEW
Khalil Kreidieh, Rana Charide, Ghassan Dbaibo, Nada M Melhem
Norovirus (NoV) is considered the second leading cause of viral acute gastroenteritis (AGE). To our knowledge, there are no systematic reviews assessing the role of NoV in AGE in the Middle East and North Africa (MENA) region. Consequently, we conducted an extensive systematic literature review on articles studying NoV in the 24 countries of the MENA region during the past 15 years (2000-2015). The methods and reporting were set according to the 2015 PRISMA-P and based on the elements from the international prospective register of systematic reviews (PROSPERO)...
November 10, 2017: Virology Journal
https://www.readbyqxmd.com/read/29102999/prospective-cohort-study-to-investigate-the-burden-and-transmission-of-acute-gastroenteritis-in-care-homes-a-study-protocol
#19
Thomas Inns, Anna Pulawska-Czub, John P Harris, Roberto Vivancos, Jonathan M Read, Nicholas J Beeching, David J Allen, Miren Iturriza-Gomara, Sarah J O'Brien
INTRODUCTION: Noroviruses are the leading cause of acute gastroenteritis in all age groups, but illness is more severe and causes excess mortality in the elderly, particularly those in long-term care. The total burden of norovirus disease in the elderly in the UK is poorly defined; no current surveillance programmes systematically or accurately quantify norovirus infection in those living in care homes. The aim of this study is to evaluate an enhanced surveillance system for acute gastroenteritis among the elderly in care homes...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29089317/diagnostic-accuracy-of-three-clinical-dehydration-scales-a-systematic-review
#20
Anna Falszewska, Hania Szajewska, Piotr Dziechciarz
OBJECTIVE: To systematically assess the diagnostic accuracy of the Clinical Dehydration Scale (CDS), the WHO Scale and the Gorelick Scale in identifying dehydration in children with acute gastroenteritis (AGE). DESIGN: Three databases, two registers of clinical trials and the reference lists from identified articles were searched for diagnostic accuracy studies in children with AGE. The index tests were the CDS, WHO Scale and Gorelick Scale, and reference standard was the percentage loss of body weight...
October 31, 2017: Archives of Disease in Childhood
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