keyword
MENU ▼
Read by QxMD icon Read
search

Variation

keyword
https://www.readbyqxmd.com/read/28449540/anisotropy-of-single-crystal-silicon-in-nanometric-cutting
#1
Zhiguo Wang, Jiaxuan Chen, Guilian Wang, Qingshun Bai, Yingchun Liang
The anisotropy exhibited by single-crystal silicon in nanometric cutting is very significant. In order to profoundly understand the effect of crystal anisotropy on cutting behaviors, a large-scale molecular dynamics model was conducted to simulate the nanometric cutting of single-crystal silicon in the (100)[0-10], (100)[0-1-1], (110)[-110], (110)[00-1], (111)[-101], and (111)[-12-1] crystal directions in this study. The simulation results show the variations of different degrees in chip, subsurface damage, cutting force, and friction coefficient with changes in crystal plane and crystal direction...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28449410/the-impact-of-the-affordable-care-act-on-self-employment
#2
Bradley T Heim, Lang Kate Yang
This paper estimates the impact of the implementation of the Affordable Care Act (ACA) in 2014 on the decision to be self-employed. Using data from the Current Population Survey, we employ two identification strategies. Utilizing prereform variation in state nongroup health insurance market regulations, we find that the ACA did not increase self-employment overall in states that lacked similar provisions in their nongroup markets prior to 2014. In specifications that utilize variation across individuals in characteristics that could make it harder for them to purchase insurance if they left their current employer, we also do not find that the ACA differentially increased self-employment...
April 27, 2017: Health Economics
https://www.readbyqxmd.com/read/28449408/prediabetes-is-associated-with%C3%A2-genetic-variations-in-the-kir6-2-subunit%C3%A2-kcnj11-%C3%A2-of-pancreatic-atp-sensitive-potassium-channel-gene-a-case-control-study-in-youth-han-chinese-population
#3
Min Xu, Honglin Hu, Datong Deng, Mingwei Chen, Zhenshan Xu, Youmin Wang
BACKGROUND: E23K variant of the KCNJ11 has been reported to be associated with type 2 diabetes in multiple populations. However, little is known about the role of E23K polymorphism of the KCNJ11 in the development of prediabetes in youth in China. METHODS: To this end, we recruited 279 subjects with prediabetes and 240 normal controls. RESULTS: We found that prediabetic Chinese youth exhibited higher carrier rate of K23-allele-containing genotypes than control subjects (p = 0...
April 27, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28449374/genetic-variability-in-adenosine-deaminase-like-contributes-to-variation-in-alcohol-preference-in-mice
#4
Heidi M B Lesscher, Alexis Bailey, Louk J M J Vanderschuren
BACKGROUND: A substantial part of the risk for alcohol use disorder (AUD) is determined by genetic factors. We previously used chromosome substitution (CSS) mice, to identify a QTL for alcohol preference on mouse chromosome 2. The aim of this study was to identify candidate genes within this QTL that confer the risk for alcohol preference. METHODS: In order to delineate the neurobiological underpinnings of alcohol consumption, we expanded on the QTL approach to identify candidate genes for high alcohol preference in mice...
April 27, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28449315/panelcn-mops-copy-number-detection-in-targeted-ngs-panel-data-for-clinical-diagnostics
#5
Gundula Povysil, Antigoni Tzika, Julia Vogt, Verena Haunschmid, Ludwine Messiaen, Johannes Zschocke, Günter Klambauer, Sepp Hochreiter, Katharina Wimmer
Targeted next-generation-sequencing (NGS) panels have largely replaced Sanger sequencing in clinical diagnostics. They allow for the detection of copy number variations (CNVs) in addition to single-nucleotide-variants and small insertions/deletions. However, existing computational CNV detection methods have shortcomings regarding accuracy, quality control, incidental findings, and user-friendliness. We developed panelcn.MOPS, a novel pipeline for detecting CNVs in targeted NGS panel data. Using data from 180 samples, we compared panelcn...
April 27, 2017: Human Mutation
https://www.readbyqxmd.com/read/28449302/prescribing-safety-assessment-2016-delivery-of-a-national-prescribing-assessment-to-7-343-uk-final-year-medical-students
#6
Simon R J Maxwell, Jamie J Coleman, Lynne Bollington, Celia Taylor, David J Webb
AIM(S): Newly graduated doctors write a large proportion of prescriptions in UK hospitals but recent studies have shown that they frequently make prescribing errors. The Prescribing Safety Assessment (PSA) has been developed as an assessment of competence in relation to prescribing and supervising the use of medicines. This report describes the delivery of the PSA to all UK final-year medical students in 2016 (PSA2016). METHODS: The PSA is a 2-hour online assessment comprising eight sections which cover various aspects of prescribing defined within the outcomes of undergraduate education identified by the UK General Medical Council...
April 27, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28449244/indications-and-extent-of-central-neck-dissection-for-papillary-thyroid-cancer-an-american-head-and-neck-society-consensus-statement
#7
Nishant Agrawal, Maria R Evasovich, Emad Kandil, Salem I Noureldine, Erin A Felger, Ralph P Tufano, Dennis H Kraus, Lisa A Orloff, Raymon Grogan, Peter Angelos, Brendan C Stack, Bryan McIver, Gregory W Randolph
BACKGROUND: The primary purposes of this interdisciplinary consensus statement were to review the relevant indications for central neck dissection (CND) in patients with papillary thyroid cancer (PTC) and to outline the appropriate extent and relevant techniques required to accomplish a safe and effective CND. METHODS: A writing group convened by the American Head and Neck Society (AHNS) Endocrine Committee was tasked with identifying the important clinical elements to consider when managing the central neck compartment in patients with PTC based on available evidence in the literature, and the group's collective experience...
April 27, 2017: Head & Neck
https://www.readbyqxmd.com/read/28449200/species-traits-as-predictors-of-range-shifts-under-contemporary-climate-change-a-review-and-meta-analysis
#8
Sarah A MacLean, Steven R Beissinger
A growing body of literature seeks to explain variation in range shifts using species' ecological and life history traits, with expectations that shifts should be greater in species with greater dispersal ability, reproductive potential, and ecological generalization. Despite strong theoretical support for species' traits as predictors of range shifts, empirical evidence from contemporary range shift studies remains limited in extent and consensus. We conducted the first comprehensive review of species' traits as predictors of range shifts, collecting results from 51 studies across multiple taxa encompassing over 11,000 species' responses for 54 assemblages of taxonomically-related species occurring together in space...
April 27, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28449156/development-of-multiple-unit-floating-drug-delivery-system-of-clarithromycin-formulation-in-vitro-dissolution-by-modified-dissolution-apparatus-in-vivo-radiographic-studies-in-human-volunteers
#9
Arun B Reddy, Narendar D Reddy
Clarithromycin (CM), a broad spectrum macrolide antibiotic used to eradicate H. pylori in peptic ulcer. Clarithromycin (CM) is well absorbed from the gastrointestinal tract, but has a bioavailability of 50% due to rapid biodegradation. The aim of this investigation was to increase the gastric residence time, and to control the drug release of clarithromycin by formulating into multiple unit floating mini-tablets. Floating tablets were prepared by using direct compression method with HPMC K4M and Polyox WSR 1105 as release retarded polymers and sodium bicarbonate as gas generating agent...
April 27, 2017: Drug Research
https://www.readbyqxmd.com/read/28449098/insights-on-persistent-airway-infection-by-nontypeable-haemophilus-influenzae-in-chronic-obstructive-pulmonary-disease
#10
Christian P Ahearn, Mary C Gallo, Timothy F Murphy
Nontypeable Haemophilus influenzae (NTHi) is the most common bacterial cause of infection of the lower airways in adults with chronic obstructive pulmonary disease (COPD). Infection of the COPD airways causes acute exacerbations, resulting in substantial morbidity and mortality. NTHi has evolved multiple mechanisms to establish infection in the hostile environment of the COPD airways, allowing the pathogen to persist in the airways for months to years. Persistent infection of the COPD airways contributes to chronic airway inflammation that increases symptoms and accelerates the progressive loss of pulmonary function, which is a hallmark of the disease...
April 25, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28449093/opinions-of-lung-cancer-clinicians-on-shared-decision-making-in-early-stage-non-small-cell-lung-cancer%C3%A2
#11
Sahar Mokhles, Alex P W M Maat, Joachim G J V Aerts, Joost J M E Nuyttens, Ad J J C Bogers, Johanna J M Takkenberg
OBJECTIVES: To investigate the opinions of lung cancer clinicians concerning shared decision making (SDM) in early-stage non-small-cell lung cancer patients. METHODS: A survey was conducted among Dutch cardiothoracic surgeons and lung surgeons, pulmonologists and radiation oncologists. The opinions of clinicians on the involvement of patients in treatment decision making was assessed using a 1-5 Likert-type scale. Through open questions, we queried barriers to and drivers of SDM in clinical practice...
April 25, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28449076/qtl-analysis-of-the-developmental-response-to-l-glutamate-in-arabidopsis-roots-and-its-genotype-by-environment-interactions
#12
Pia Walch-Liu, Rhonda C Meyer, Thomas Altmann, Brian G Forde
Primary root growth in Arabidopsis and a number of other species has previously been shown to be remarkably sensitive to the presence of external glutamate, with glutamate signalling eliciting major changes in root architecture. Using two recombinant inbred lines from reciprocal crosses between Arabidopsis accessions C24 and Col-0, we have identified one large-effect quantitative trait locus (QTL), GluS1, and two minor QTLs, GluS2 and GluS3, which together accounted for 41% of the phenotypic variance in glutamate sensitivity...
April 26, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28449073/genetics-of-phenotypic-plasticity-and-biomass-traits-in-hybrid-willows-across-contrasting-environments-and-years
#13
Sofia Berlin, Henrik R Hallingbäck, Friderike Beyer, Nils-Erik Nordh, Martin Weih, Ann-Christin Rönnberg-Wästljung
Background and Aims: Phenotypic plasticity can affect the geographical distribution of taxa and greatly impact the productivity of crops across contrasting and variable environments. The main objectives of this study were to identify genotype-phenotype associations in key biomass and phenology traits and the strength of phenotypic plasticity of these traits in a short-rotation coppice willow population across multiple years and contrasting environments to facilitate marker-assisted selection for these traits...
April 25, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28448948/interactions-between-the-vascular-endothelial-growth-factor-gene-polymorphism-and-life-events-in-susceptibility-to-major-depressive-disorder-in-a-chinese-population
#14
Dong Han, Zhengxue Qiao, Lu Chen, Xiaohui Qiu, Deyu Fang, Xiuxian Yang, Jingsong Ma, Mingqi Chen, Jiarun Yang, Lin Wang, Xiongzhao Zhu, Congpei Zhang, Yanjie Yang, Hui Pan
BACKGROUND: Recent studies suggest that vascular endothelial growth factor (VEGF) is involved in the development of major depressive disorder. The aim of this study is to investigate the interaction between vascular endothelial growth factor (VEGF) polymorphism (+405G/C, rs2010963) and negative life events in the pathogenesis of major depressive disorder (MDD). METHODS: DNA genotyping was performed on peripheral blood leukocytes in 274 patients with MDD and 273 age-and sex-matched controls...
April 19, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28448941/geochemistry-and-microbial-diversity-of-cave-waters-in-the-gypsum-karst-aquifers-of-emilia-romagna-region-italy
#15
Ilenia M D'Angeli, Diana I Serrazanetti, Chiara Montanari, Lucia Vannini, Fausto Gardini, Jo De Waele
Fifty-seven control points of waters (sinking streams, rivers in caves, and resurgences) hosted in gypsum karst areas in Emilia Romagna region (N-Italy) were sampled in the framework of a Project LIFE+08NAT/IT/000369 "Gypsum" in the period 2010-2014. The microbiology and chemistry of these waters have been analyzed to evaluate the impact of human activities or natural factors, in the gypsum karst systems. Waters have been analyzed for major chemistry (Ca, Mg, Na, K, SO4, HCO3, Cl, NO3) and some minor constituents (F, Br, NH4 and PO4), measuring pH, electric conductivity (EC), total dissolved solids (TDS) and temperature (T) in situ...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448935/analysis-of-the-synoptic-winter-mortality-climatology-in-five-regions-of-england-searching-for-evidence-of-weather-signals
#16
A K Paschalidou, P A Kassomenos, G R McGregor
Although heat-related mortality has received considerable research attention, the impact of cold weather on public health is less well-developed, probably due to the fact that physiological responses to cold weather can vary substantially among individuals, age groups, diseases etc., depending on a number of behavioral and physiological factors. In the current work we use the classification techniques provided by the COST-733 software to link synoptic circulation patterns with excess cold-related mortality in 5 regions of England...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448932/seasonal-changes-of-fructans-in-dimorphic-roots-of-ichthyothere-terminalis-spreng-blake-asteraceae-growing-in-cerrado
#17
Lorrayne Veloso de Almeida, Pedro Henrique Ferri, José Carlos Seraphin, Moemy Gomes de Moraes
Cerrado is a floristically rich savanna in Brazil, whose vegetation consists of a physiognomic mosaic, influenced by rainfall seasonality. In the dry season rainfall is substantially lower and reduces soil water supply, mainly for herbs and subshrubs. Climatic seasonal variations may well define phenological shifts and induce fluctuations of plant reserve pools. Some Cerrado native species have thickened underground organs that bear buds and store reserves, as adaptive features to enable plant survival following environmental stresses...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448931/tree-growth-climate-relationships-in-a-forest-plot-network-on-mediterranean-mountains
#18
Nikolaos M Fyllas, Anastasia Christopoulou, Alexandros Galanidis, Chrysanthi Z Michelaki, Panayiotis G Dimitrakopoulos, Peter Z Fulé, Margarita Arianoutsou
In this study we analysed a novel tree-growth dataset, inferred from annual ring-width measurements, of 7 forest tree species from 12 mountain regions in Greece, in order to identify tree growth - climate relationships. The tree species of interest were: Abies cephalonica, Abies borisii-regis, Picea abies, Pinus nigra, Pinus sylvestris, Fagus sylvatica and Quercus frainetto growing across a gradient of climate conditions with mean annual temperature ranging from 5.7 to 12.6°C and total annual precipitation from 500 to 950mm...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448927/time-varying-sensitivity-analysis-of-hydrologic-and-sediment-parameters-at-multiple-timescales-implications-for-conservation-practices
#19
Hui Xie, Zhenyao Shen, Lei Chen, Jiali Qiu, Jianwei Dong
Environmental models can be used to better understand the hydrologic and sediment behavior in a watershed system. However, different processes may dominate at different time periods and timescales, which highly complicate the model interpretation. The related parameter uncertainty may be significant and needs to be addressed to avoid bias in the watershed management. In this study, we used the time-varying and multi-timescale (TVMT) method to characterize the temporal dynamics of parameter sensitivity at different timescales in hydrologic and sediment modeling...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448925/geostatistics-as-a-tool-to-improve-the-natural-background-level-definition-an-application-in-groundwater
#20
Nico Dalla Libera, Paolo Fabbri, Leonardo Mason, Leonardo Piccinini, Marco Pola
The Natural Background Level (NBL), suggested by UE BRIDGE project, is suited for spatially distributed datasets providing a regional value that could be higher than the Threshold Value (TV) set by every country. In hydro-geochemically dis-homogeneous areas, the use of a unique regional NBL, higher than TV, could arise problems to distinguish between natural occurrences and anthropogenic contaminant sources. Hence, the goal of this study is to improve the NBL definition employing a geostatistical approach, which reconstructs the contaminant spatial structure accounting geochemical and hydrogeological relationships...
April 24, 2017: Science of the Total Environment
keyword
keyword
80755
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"