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Statistical process control

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https://www.readbyqxmd.com/read/29783216/-complex-of-psycho-hygienic-correction-measures-of-personality-features-of-hiv-infected-men-and-evaluation-of-their-efficiency
#1
Ihor V Serheta, Oksana B Dudarenko, Olha P Mostova, Tetiana V Lobastova, Vitalii M Andriichuk, Larysa M Vakolyuk, Olha M Yakubovska
OBJECTIVE: Introduction: In addition to adequate diagnosis and treatment of HIV-infected individuals, development, scientific substantiation and implementation of psycho-hygienic measures aimed at correcting the processes of forming personality traits and improving the psycho-emotional state of HIV-infected individuals are of particular importance. The aim: The purpose of the scientific research was to determine the most significant changes of situational and personal anxiety indicators, the degree of gravity of the asthenic state and depressive manifestations that were recorded in the context of the introduction of a number of measures for psycho-hygienic correction...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783212/changes-in-biochemical-parameters-of-oral-fluid-in-patients-during-the-orthodontic-treatment-with-a-bracket-system-under-the-action-of-a-developed-mucosal-gel-with-probiotic
#2
Anna V Voronkova, Lyubov V Smaglyuk
OBJECTIVE: Introduction: Many research studies involving orthodontic patients focus on changes in levels of oral microbiocenosis after bracket placement. Based upon this the objective of the current study was to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system. The aim: Aim of our study is to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783020/immune-modulation-of-a-novel-lipid-soluble-extract-of-pinellia-pedatisecta-schott-in-the-tumor-microenvironment-of-an-hpv-tumor-burdened-mouse-model
#3
Haixia Huang, Mingxing Zhang, Meng Zhang, Jing Peng, Guiling Li, Congjian Xu, Suiqi Gui
ETHNOPHARMACOLOGICAL RELEVANCE: Pinellia pedatisecta Schott extract (PE), a traditional Chinese medicine, has been used to reduce swelling, dry dampness and suppress cervical tumors. AIMS: To evaluate the roles of PE in the regulation of anti-tumor effects and the cellular immune response in the tumor microenvironment. METHODS: The immune microenvironment of HPV+ TC-1 tumors was examined by immunohistochemistry, real-time PCR and flow cytometry...
May 18, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29782312/naturalistic-driving-study-investigating-self-regulation-behavior-in-early-alzheimer-s-disease-a-pilot-study
#4
Laurence Paire-Ficout, Sylviane Lafont, Fanny Conte, Amandine Coquillat, Colette Fabrigoule, Joël Ankri, Frédéric Blanc, Cécilia Gabel, Jean-Luc Novella, Isabella Morrone, Rachid Mahmoudi
BACKGROUND: Because cognitive processes decline in the earliest stages of Alzheimer's disease (AD), the driving abilities are often affected. The naturalistic driving approach is relevant to study the driving habits and behaviors in normal or critical situations in a familiar environment of participants. OBJECTIVE: This pilot study analyzed in-car video recordings of naturalistic driving in patients with early-stage AD and in healthy controls, with a special focus on tactical self-regulation behavior...
May 16, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29781353/clinical-trials-with-multiple-endpoints-can-establish-a-correlation-but-not-yet-causality-between-dietary-supplementation-with-omega-3-fatty-acids-and-keratoconjunctivitis-sicca
#5
Roger Lee Mendoza
AIM: We review clinical evidence of therapeutic efficacy and effectiveness of omega-3 fatty acids (omega-3s) in keratoconjunctivitis sicca, colloquially known as dry eye disease. In doing so, we identify relevant literature to address the following questions: 1) What definitive guidance can clinical evidence offer eye physicians and their patients? 2) What aspects of omega-3 supplementation lack definitive evidence, and how might economic assessments help? METHODS: A targeted and systematic search strategy based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was designed in this study for refereed clinical trials of omega-3s in dry eye treatment...
May 21, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29780985/the-correlation-between-gelatin-macroscale-differences-and-nanoparticle-properties-providing-insight-into-biopolymer-variability
#6
André T Stevenson, Danny J Jankus, Max A Tarshis, Abby R Whittington
From therapeutic delivery to sustainable packaging, manipulation of biopolymers into nanostructures imparts biocompatibility to numerous materials with minimal environmental pollution during processing. While biopolymers are appealing natural based materials, the lack of nanoparticle (NP) physicochemical consistency has decreased their nanoscale translation into actual products. Insights regarding the macroscale and nanoscale property variation of gelatin, one of the most common biopolymers already utilized in its bulk form, are presented...
May 21, 2018: Nanoscale
https://www.readbyqxmd.com/read/29779982/statistical-control-of-the-production-of-blood-components-by-control-charts-of-attribute-to-improve-quality-characteristics-and-to-comply-with-current-specifications
#7
REVIEW
Paulo Pereira, Jerard Seghatchian, Beatriz Caldeira, Sandra Xavier, Gracinda de Sousa
Statistical process control (SPC) is closely related to good quality control practices in the manufacturing process. One of the primary goals is to detect unnatural patterns, allowing the production service to control the conformity of the blood components produced. Despite being recommended by national and international standards, its exercise is not uniform, and sometimes the methodology used is misinterpreted as SPC. When the input data has a Gaussian distribution, control charts for variables are proposed...
May 8, 2018: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29779485/tgn-1412-and-bia-2474-trials-with-tragic-end-lessons-learnt-to-make-clinical-trials-safer
#8
Rimple Jeet Kaur, Surjit Singh, Preeti Sidhu, Pramod Kumar Sharma
BACKGROUND: Globally, there have been tremendous efforts by regulatory authorities to make clinical trials safer by making stringent clinical trial regulations. Despite this, we witnessed several tragic events. TGN1412 and BIA 10-2474 phase I trials are infamous trails in which healthy volunteers either succumbed to severe adverse effects or faced irreversible impairments of the test drug. Such afflictions in clinical trials are not only turbulent to the image of pharmaceutical industry but it also conveys dispiriting message for clinical trial participants...
May 20, 2018: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/29776106/local-yield-stress-statistics-in-model-amorphous-solids
#9
Armand Barbot, Matthias Lerbinger, Anier Hernandez-Garcia, Reinaldo García-García, Michael L Falk, Damien Vandembroucq, Sylvain Patinet
We develop and extend a method presented by Patinet, Vandembroucq, and Falk [Phys. Rev. Lett. 117, 045501 (2016)PRLTAO0031-900710.1103/PhysRevLett.117.045501] to compute the local yield stresses at the atomic scale in model two-dimensional Lennard-Jones glasses produced via differing quench protocols. This technique allows us to sample the plastic rearrangements in a nonperturbative manner for different loading directions on a well-controlled length scale. Plastic activity upon shearing correlates strongly with the locations of low yield stresses in the quenched states...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776098/effect-of-multiplicative-noise-on-stationary-stochastic-process
#10
A V Kargovsky, A Yu Chikishev, O A Chichigina
An open system that can be analyzed using the Langevin equation with multiplicative noise is considered. The stationary state of the system results from a balance of deterministic damping and random pumping simulated as noise with controlled periodicity. The dependence of statistical moments of the variable that characterizes the system on parameters of the problem is studied. A nontrivial decrease in the mean value of the main variable with an increase in noise stochasticity is revealed. Applications of the results in several physical, chemical, biological, and technical problems of natural and humanitarian sciences are discussed...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775553/influence-of-photobiomodulation-therapy-on-gingivitis-induced-by-multi-bracket-appliances-a-split-mouth-randomized-controlled-trial
#11
Steffen Stein, Michael Schauseil, Andreas Hellak, Heike Korbmacher-Steiner, Andreas Braun
OBJECTIVE: The objective of this split-mouth trial was to investigate the influence of photobiomodulation therapy (PBMT) on adjuvant treatment of gingivitis induced by multi-bracket appliances, after bracket debonding and professional tooth cleaning. MATERIALS AND METHODS: Thirteen patients (mean age 16.15 years; standard deviation ±2.12 years) who had completed active orthodontic treatment with fixed orthodontic appliances in an orthodontic clinic were included on a randomized basis...
May 18, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29772880/detection-of-spatial-aggregation-of-cases-of-cancer-from-data-on-patients-and-health-centres-contained-in-the-minimum-basic-data-set
#12
Pablo Fernández-Navarro, Jose-Miguel Sanz-Anquela, Angel Sánchez Pinilla, Rosario Arenas Mayorga, Carmen Salido-Campos, Gonzalo López-Abente
The feasibility of the Minimum Basic Data Set (MBDS) as a tool in cancer research was explored monitoring its incidence through the detection of spatial clusters. Case-control studies based on MBDS and marked point process were carried out with the focus on the residence of patients from the Prince of Asturias University Hospital in Alcalá de Henares (Madrid, Spain). Patients older than 39 years with diagnoses of stomach, colorectal, lung, breast, prostate, bladder and kidney cancer, melanoma and haematological tumours were selected...
May 7, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29772289/nose-to-brain-drug-delivery-an-update-on-clinical-challenges-and-progress-towards-approval-of-anti-alzheimer-drugs
#13
REVIEW
Mukta Agrawal, Swarnlata Saraf, Shailendra Saraf, Sophia G Antimisiaris, Mahavir Chougule, Sunday A Shoyele, Amit Alexander
According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the year 2017 itself, the cost of AD treatment in the USA has been reported to rise to $259 billion. This statistic shows the severity of the disease in the USA which is very much similar across the globe. On the other hand, the treatment remains limited to a few conventional oral medications (approved by FDA). These are mainly acting superficially from mild to the moderate AD...
May 14, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29770936/source-identification-and-spatial-distribution-of-metals-in-soils-in-a-typical-area-of-the-lower-yellow-river-eastern-china
#14
Jianshu Lv, Yuanhe Yu
In this study, 234 soil samples were recently collected from Gaoqing County (a typical area of the lower Yellow River) to determine the contents of As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn. Multivariate statistical analyses such as correlation analysis, principal components analysis, and one-way ANOVA were applied to identify the source of metals in the soil. Geostatistical methods were used to analyze the spatial structure and distribution of the metals. The results indicated that the mean contents of all metals exceeded the background value of the lower Yellow River, especially for As, Cu, and Hg (1...
May 16, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29769591/clinical-retrospective-case-control-study-on-the-mechanics-of-obstacle-in-mouth-opening-and-malocclusion-in-patients-with-maxillofacial-fractures
#15
Hai-Hua Zhou, Kun Lv, Rong-Tao Yang, Zhi Li, Xue-Wen Yang, Zu-Bing Li
This study aims to identify and distinguish various factors that may influence the clinical symptoms (limited mouth opening and malocclusion) in patients with maxillofacial fractures. From January 2000 to December 2009, 963 patients with maxillofacial fractures were enrolled in this statistical study to aid in evaluating the association between various risk factors and clinical symptoms. Patients with fractured posterior mandibles tended to experience serious limitation in mouth opening. Patients who sustained coronoid fractures have the highest risk of serious limitation in mouth opening (OR = 9...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29769242/implementing-parental-tobacco-dependence-treatment-within-bronchiolitis-qi-collaboratives
#16
Susan C Walley, Grant M Mussman, Michele Lossius, Kristin A Shadman, Lauren Destino, Matthew Garber, Shawn L Ralston
BACKGROUND AND OBJECTIVES: We sought to implement systematic tobacco dependence interventions for parents and/or caregivers as secondary aims within 2 multisite quality improvement (QI) collaboratives for bronchiolitis. We hypothesized that iterative improvements in tobacco dependence intervention strategies would result in improvement in outcomes between collaboratives. METHODS: This study involved 2 separate yearlong, multisite QI collaboratives that were focused on care provided to inpatients with a primary diagnosis of bronchiolitis...
May 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29766701/new-multi-targeting-strategy-in-hair-growth-promotion-in-vitro-and-in-vivo-studies
#17
Barbara Marzani, Daniela Pinto, Elisabetta Sorbellini, Fabio Rinaldi
BACKGROUND: Considering the importance of hair in our modern society and the impact of hair loss, the efforts of researchers are addressed to better understand the mechanisms behind the hair cycle regulation and dysregulation. Because hair loss is multifactorial, differenced and new approaches are required. In particular we addressed our attention to two recently identified targets in hair cycling and growth control: olfactory receptor and autophagy. The aim of the study was to evaluate: the possible pro-autophagic effect of N1-methylspermidine (a spermidine analogue) in vitro and, in a double blind clinical trial, the safety and efficacy of topical daily application of a lotion containing N1-methylspermidine and Sandalore®...
June 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29766257/the-impact-of-exercise-on-sleep-time-quality-and-disturbance-in-patients-with-rheumatoid-arthritis-a-study-protocol-for-a-pilot-randomised-controlled-trial
#18
Sean G McKenna, Alan E Donnelly, Bente A Esbensen, Alexander D Fraser, Norelee M Kennedy
Poor sleep is an issue for people with rheumatoid arthritis (RA), which may curtail their ability to function appropriately and reduce their activity levels. This paper describes a protocol for a pilot randomised controlled trial of an aerobic exercise intervention compared with exercise advice designed to improve sleep in people with RA. Objectives are to obtain reliable estimates regarding recruitment rates, participant retention and protocol adherence and to generate potential effect size estimates for a main trial...
May 15, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29764434/real-time-monitoring-of-the-budding-index-in-saccharomyces-cerevisiae-batch-cultivations-with-in-situ-microscopy
#19
Anna-Maria Marbà-Ardébol, Jörn Emmerich, Michael Muthig, Peter Neubauer, Stefan Junne
BACKGROUND: The morphology of yeast cells changes during budding, depending on the growth rate and cultivation conditions. A photo-optical microscope was adapted and used to observe such morphological changes of individual cells directly in the cell suspension. In order to obtain statistically representative samples of the population without the influence of sampling, in situ microscopy (ISM) was applied in the different phases of a Saccharomyces cerevisiae batch cultivation. The real-time measurement was performed by coupling a photo-optical probe to an automated image analysis based on a neural network approach...
May 15, 2018: Microbial Cell Factories
https://www.readbyqxmd.com/read/29763977/transforming-care-to-evidence-based-practice-with-scripted-messages-an-improvement-project-for-pain-management-in-outpatient-surgical-patients
#20
Lanell M Bellury, Karen Mullinax, Judi Mozingo, Berta Dantzler, Nancy McGee
BACKGROUND: Outpatient surgeries are common and most patients experience pain postoperatively requiring nursing attention to pain management. Scripting, recommended for consistent, targeted communication to improve patient satisfaction, has limited evidence to support its use. AIMS: To explore the effect of scripted messages on self-reported pain control and patient satisfaction with care in outpatient surgical patients. METHODS: A retrospective medical record review pre- and postintervention evaluated a pain management scripted message delivered at two time points (preoperatively and postoperatively)...
May 15, 2018: Worldviews on Evidence-based Nursing
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