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A Schaller, C Metz-Favre, L Guenard-Bilbaut, F De Blay
The Fernand Widal syndrome is a set of associations between asthma, nasal polyposis and aspirin sensitivity. Selective cyclo-oxygenase 2 (COX 2) inhibitors are recognized as being a therapeutic alternative in cases needing analgesic or anti-inflammatory treatment. In a retrospective study, we have compiled data concerning oral provocation tests (OPT) undertaken with celecoxib, one of most the selective COX 2 inhibitors, in eight patients with the Fernand Widal syndrome. They were compared with twenty-seven control patients with sensitivity to aspirin or non-steroidal anti-inflammatories, manifesting as asthma, urticaria or rhino-conjunctivitis...
February 17, 2018: Revue des Maladies Respiratoires
Abhilasha Karunasagar, Santosh S Garag, Suma B Appannavar, Raghavendra D Kulkarni, Ashok S Naik
To study the microbiological profile in patients with chronic rhino-sinusitis. To correlate disease severity with the presence of biofilms and host risk factors. To assess outcome of Sinus Surgery 2 weeks post operatively in terms of presence of bacteria and their ability to form biofilm. Prospective study. 50 cases of chronic rhino-sinusitis requiring Functional Endoscopic Sinus Surgery admitted in SDM Hospital, Dharwad, Karnataka were studied using intra-operative mucosal samples for microbiological analysis...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
J-P Mutebi, M B Crabtree, R C Kading, A M Powers, J P Ledermann, E C Mossel, N Zeidner, J J Lutwama, B R Miller
Despite evidence of arbovirus activity in northwestern Uganda (West Nile Sub-region), there is very limited information on the mosquito fauna of this region. The only published study reported 52 mosquito species in northwestern Uganda but this study took place in 1950 and the information has not been updated for more than 60 yr. In January and June 2011, CO2 baited-light traps were used to collect 49,231 mosquitoes from four different locations, Paraa (9,487), Chobe (20,025), Sunguru (759), and Rhino Camp (18,960)...
February 12, 2018: Journal of Medical Entomology
Kazuhiro Nomura, Hiroyuki Ikushima, Daiki Ozawa, Yuichi Shimizu, Kazuya Arakawa, Jun Suzuki, Hiroshi Hidaka, Yukio Katori, Kenji Ohyama
Sinus fungal ball is defined as noninvasive chronic rhino-sinusitis with a clump of mold in the paranasal sinuses, typically affecting the maxillary sinus. Fairly good outcomes of endoscopic surgery have been reported where the ball is removed through the antrostomy. However, the affected sinus tends to have a smaller cavity and thicker bony walls. As such, it is often challenging to maintain a window size that is sufficient to control possible recurrence. The endoscopic modified medial maxillectomy procedure was applied to a 61-year old and a 70-year old female patient with maxillary sinus fungal ball...
February 12, 2018: Journal of Craniofacial Surgery
Asmat Ullah, Muhammad Umair, Shabir Hussain, Abid Jan, Wasim Ahmad
No abstract text is available yet for this article.
February 13, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
Michael Gross
The family Rhinocerotidae with many species spread around the world was a distinct feature of the global Pleistocene fauna, but most of these species are now extinct. Three of the five surviving species are critically endangered, due to habitat loss and a surge in criminal hunting for horns. To save these iconic species, conservation science will have to apply all methods at its disposal, from population management through to advanced genomics and forensics. Michael Gross reports.
January 8, 2018: Current Biology: CB
Ryotaro Torai, Teruhiko Makino, Megumi Mizawa, Yutaka Shimomura, Tadamichi Shimizu
No abstract text is available yet for this article.
February 5, 2018: European Journal of Dermatology: EJD
F Simon, M Haggard, R M Rosenfeld, H Jia, S Peer, M-N Calmels, V Couloigner, N Teissier
Otitis media with effusion (OME) is a common childhood disease defined as the presence of liquid in the middle ear without signs or symptoms of acute ear infection. Children can be impacted mainly with hearing impairment and/or co-occurring recurrent acute otitis media (AOM) thus requiring treatment. Although many meta-analyses and national guidelines have been issued, management remains difficult to standardize, and use of surgical and medical treatments continue to vary. We convened an international consensus conference as part of the 2017 International Federation of Oto-rhino-laryngological Societies Congress, to identify best practices in OME management...
February 2, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
Nadia Benmoussa, Kevin Hansen, Philippe Charlier
INTRODUCTION: Hippocrates, a Greek physician during the fifth century BC., is often considered the father of medicine. The Corpus Hippocraticum comprising of 58 volumes was attributed to him alone for a long time. Nowadays, it is considered that several authors contributed to its creation between 450 and 150 BC., so over a period of 300 years. The objective of our study was to develop a nosological classification of all passages treating head and neck diseases. MATERIAL AND METHODS: We read and analyzed all volumes of the Corpus Hippocraticum in French translation and extracted all passages dealing with oto-rhino-laryngological and maxillo-facial conditions (n = 65)...
January 31, 2018: Acta Oto-laryngologica
A Farinetti, A Raji, H Wu, B Wanna, C Vincent
The prevalence of hearing loss in newborns and infants is estimated between 1 to 3.47 cases per 1000 live births. Early diagnosis and rehabilitation of congenital hearing loss are mandatory in order to achieve a satisfactory linguistic and cognitive development. Without appropriate opportunities to learn language, these children will fall behind their normal hearing peers in communication, cognition, reading and socio-emotional development. After promising results, neonatal screening for hearing loss and audiological evaluation are becoming more extensively carried out...
January 20, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
Graciela Fernández Blanco, Maria Cecilia Madeo, Mariana Martínez, María Emilia Vázquez
We report a 42-year-old cocaine addicted female patient referred for evaluation of hard palate ulceration resulting in oro-sinus communication with difficulties in swallowing and phonation, an rhino-sinusitis. Acrylic and removable silicone prosthesis was prescribed to relieve severe functional disorders. It is essential that the patient permanently abandons cocaine use to perform surgical reconstruction.
November 2017: Anais Brasileiros de Dermatologia
Natalia Akulenko, Sergei Ryazansky, Valeriya Morgunova, Pavel A Komarov, Ivan Olovnikov, Chantal Vaury, Silke Jensen, Alla Kalmykova
Expression of transposable elements in the germline is controlled by Piwi-interacting (pi) RNAs produced by genomic loci termed piRNA clusters and associated with Rhino, a Heterochromatin Protein 1 (HP1) homolog. Previously, we have shown that transgenes containing a fragment of the I retrotransposon form de novo piRNA clusters in the Drosophila germline providing suppression of I-element activity. We noted that identical transgenes located in different genomic sites vary considerably in piRNA production and classified them as "strong" and "weak" piRNA clusters...
January 22, 2018: RNA
K Vogt, G Bachmann-Harildstad, A Lintermann, A Nechyporenko, F Peters, K D Wernecke
The report reflects an agreement based on the consensus conference of the International Standardization Committee on the Objective Assessment of the Nasal Airway in Riga, 2nd Nov. 2016. The aim of the conference was to address the existing nasal airway function tests and to take into account physical, mathematical and technical correctness as a base of international standardization as well as the requirements of the Council Directive 93/42/EEC of 14 June 1993 concerning medical devices. Rhinomanometry, acoustic rhinometry, peak nasal inspiratory flow, Odiosoft-Rhino, optical rhinometry, 24-h measurements, computational fluid dynamics, nasometry and the mirrow test were evaluated for important diagnostic criteria, which are the precision of the equipment including calibration and the software applied; validity with sensitivity, specificity, positive and negative predictive values, reliability with intra-individual and inter-individual reproducibility and responsiveness in clinical studies...
January 21, 2018: Rhinology
Purva Bavikar, Varshil Mehta
Mucormycosis is a progressively invasive disease, with a fatal outcome, on late presentation. A 38-year-old female presented with diabetic ketoacidosis with right eye ptosis and a frozen globe without any signs of inflammation, externally. She underwent transnasal endoscopic debridement of paranasal sinuses and exenteration of the right eye. The histopathology specimen revealed the growth of mucormycosis. She was treated with intravenous (IV) amphotericin B, IV insulin, and extensive debridement surgery, but had an unfavorable outcome due to rapid mucor invasion to the brain...
November 13, 2017: Curēus
Isabelle Fini Storchi, Steven Parker, Francesca Bovis, Stefano Benedicenti, Andrea Amaroli
Snoring is a sleep phenomenon due to the partial upper airway obstruction during sleep which causes vibration of the tissues of the rhino-oro-hypopharynx and less frequently the larynx. This study evaluated the use and effectiveness of the erbium:YAG 2940-nm laser as an adjunctive in providing treatment for patients suffering from chronic snoring-related sleep disorders. A prospective study of 40 consecutive patients with snoring and sleep disorders was performed, assessing data before and after three Er:YAG laser treatment sessions...
January 15, 2018: Lasers in Medical Science
Joanna Nowosielska-Grygiel, Piotr Pietkiewicz, Kalina Owczarek, Jurek Olszewski, Jarosław Miłoński
INTRODUCTION: The aim of this study was to analyse the occurrence of inverted papillomas of the nose and paranasal sinuses in patients that underwent endoscopic sinus surgery in our department. MATERIAL AND METHODS: Between 2006 and 2016, 3,574 patients underwent surgery due to paranasal sinus diseases. Patients were qualified for surgery based on medical history, computed tomography, and laboratory tests. Data were gathered from medical files, and they included age, sex, and histopathological diagnosis...
December 30, 2017: Otolaryngologia Polska
I Z Iqbal, G H Jones, N Dawe, C Mamais, M E Smith, R J Williams, I Kuhn, S Carrie
BACKGROUND: The mainstay of management of epistaxis refractory to first aid and cautery is intranasal packing. This review aimed to identify evidence surrounding nasal pack use. METHOD: A systematic review of the literature was performed using standardised methodology. RESULTS: Twenty-seven eligible articles were identified relating to non-dissolvable packs and nine to dissolvable packs. Nasal packing appears to be more effective when applied by trained professionals...
December 2017: Journal of Laryngology and Otology
Steffen Rosahl, Christopher Bohr, Michael Lell, Klaus Hamm, Heinrich Iro
Vestibular schwannomas (VS) expand slowly in the internal auditory canal, in the cerebellopontine angle, inside the cochlear and the labyrinth. Larger tumors can displace and compress the brainstem. With an annual incidence of 1:100,000 vestibular schwannoma represent 6-7% of all intracranial tumors. In the cerebellopontine angle they are by far the most neoplasm with 90% of all lesions located in this region. Magnetic resonance imaging (MRI), audiometry, and vestibular diagnostics are the mainstays of the clinical workup for patients harboring tumors...
2017: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
Mark S Springer, John Gatesy
MC5R is one of five melanocortin receptor genes found in placental mammals. MC5R plays an important role in energy homeostasis and is also expressed in the terminal differentiation of sebaceous glands. Among placental mammals there are multiple lineages that either lack or have degenerative sebaceous glands including Cetacea (whales, dolphins, and porpoises), Hippopotamidae (hippopotamuses), Sirenia (manatees and dugongs), Proboscidea (elephants), Rhinocerotidae (rhinos), and Heterocephalus glaber (naked mole rat)...
December 19, 2017: Molecular Phylogenetics and Evolution
N S Tataurshchikova, B Sangidorzh
The objective of the present study was to evaluate the clinical effectiveness of intranasal immunotherapy with the use of сycloferon in the patients presenting with seasonal virus-associated allergic rhinitis during the period of pollination. The results of the treatment of 50 patients with virus-associated allergic rhinitis (i.e. those allergic to the sagebrush pollen) were analyzed. The patients were divided into two groups depending on the therapeutic modality being used. Those comprising the main group (21 patients) received immunotherapy with сycloferon in addition to allergen-specific immunotherapy (by sublingual administration)...
2017: Vestnik Otorinolaringologii
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