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https://www.readbyqxmd.com/read/28532910/impact-of-elderly-age-on-complications-and-clinical-outcomes-following-anterior-lumbar-interbody-fusion-surgery
#1
Kevin Phan, Vignesh Ramachandran, Tommy Tran, Steven Phan, Prashanth J Rao, Ralph J Mobbs
BACKGROUND: Anterior Lumbar Interbody Fusion (ALIF) is a surgical technique used to treat patients with a variety of lumbar pathologies. Identification of risk factors leading to complication following ALIF surgery may allow surgeons to better judge candidacy and optimize care for high-risk patients. METHODS: A retrospective analysis was conducted on a prospectively collected database of 137 patients who all underwent ALIF surgery by a single primary spine surgeon...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28529579/expression-and-correlation-analysis-of-regiv-and-vascular-endothelial-growth-factors-vegf-a-and-vegf-c-in-metastatic-spinal-tumors
#2
Shuquan Zhang, Guanjie Zhao, Yi Zhao, Rui Gu, Chuangang Peng, Zhe Pu, Minfei Wu
The expression and correlation analysis of the regenerating gene family member 4 (RegIV) and vascular endothelial growth factors (VEGF-A and VEGF-C) in metastatic spinal tumors were studied. Fifteen patients with metastatic spinal tumors who underwent operation in our hospital from January 2011 to January 2013 were selected into this study. The expression level of tumor tissues in patients with spinal metastasis and RegIV, VEGF-A and VEGF-C of the corresponding paracancer normal tissue samples were evaluated by immunohistochemical staining method and the correlation between the expression of RegIV, VEGF-A and VEGF-C was analyzed...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28525477/reasons-of-dysphagia-after-operation-of-anterior-cervical-decompression-and-fusion
#3
Bing Wu, Fei Song, Shourong Zhu
STUDY DESIGN: Retrospective study. OBJECTIVE: To analyze the reasons, clinical manifestation, risk factors, prevention, and treatment of dysphagia after operation of anterior cervical decompression and fusion (ACDF). SUMMARY OF BACKGROUND DATA: Dysphagia is one of severe complications after ACDF. There were a few studies about reasons and prevention of dysphagia. METHODS: We retrospectively reviewed medical charts of patients who underwent ACDF in our hospital from January 2012 to December 2012...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28524056/dermatitis-herpetiformis-and-bone-mineral-density-analysis-of-a-french-cohort-of-53-patients
#4
Coralie Lheure, Saskia Ingen-Housz-Oro, Sandra Guignard, Rachida Inaoui, Brigitte Jolivet, Xavier Chevalier, Pierre Wolkenstein, Bruno Fautrel, Oliver Chosidow
The characteristics of patients with dermatitis herpetiformis (DH) in France is poorly documented. Furthermore, the risk of fractures and bone mineral density (BMD) in DH remain under-described, and recommendations for systematic screening for osteoporosis in DH are lacking. To describe the characteristics of DH in a large French cohort and evaluate the association between BMD and features of osteoporosis. Patients were recruited from the French Association of Gluten Intolerants (AFDIAG) and a single university dermatology department...
May 19, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28521839/associations-between-systemic-bone-mineral-density-and-early-knee-cartilage-changes-in-middle-aged-adults-without-clinical-knee-disease-a-prospective-cohort-study
#5
Andrew J Teichtahl, Yuanyuan Wang, Anita E Wluka, Boyd J Strauss, Joseph Proietto, John B Dixon, Graeme Jones, Flavia M Cicuttini
BACKGROUND: Osteoarthritis has a high prevalence in people with high bone mineral density (BMD). Nevertheless, whether high systemic BMD predates early structural features of knee osteoarthritis is unclear. This study examined the association between systemic BMD and knee cartilage defect progression and cartilage volume loss in middle-aged people without clinical knee disease. METHODS: Adults (n = 153) aged 25-60 years had total body, lumbar spine, and total hip BMD assessed by dual-energy X-ray absorptiometry at baseline (2005-2008), and tibial cartilage volume and tibiofemoral cartilage defects assessed by magnetic resonance imaging at baseline and follow up (2008-2010)...
May 18, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28520678/anterior-cruciate-ligament-injury-at-the-time-of-anterior-tibial-spine-fracture-in-young-patients-an-observational-cohort-study
#6
Meredith H Mayo, Justin J Mitchell, Derek P Axibal, Jorge Chahla, Claire Palmer, Armando F Vidal, Jason T Rhodes
BACKGROUND: Anterior tibial spine fractures (ATSF) in the skeletally immature parallel anterior cruciate ligament (ACL) tears in adult patients, yet these injuries are generally regarded as mutually exclusive. Biomechanical analysis suggests that intrinsic ACL damage occurs during ATSF, and long-term clinical studies demonstrate residual anteroposterior knee laxity following ATSF. We aim to describe prevalence, demographics, and characteristics of pediatric patients who sustained ATSF with concomitant ACL injury...
May 17, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28516878/high-incidence-of-vertebral-osteoporotic-fracture-within-the-first-year-after-liver-transplantation
#7
Sarah Butin, Isabelle Griffoul, Fabien Espitalier, Ephrem Salamé, Denis Mulleman, Philippe Goupille
OBJECTIVES: Bone loss is a complication for patients with liver diseases and after transplantation, which results in increased fracture risk. The aim of this study was to determine the incidence of osteoporotic vertebral fractures following liver transplantation. METHODS: We performed a prospective study of patients who were awaiting liver transplantation. Patients were seen at baseline (visit 1) and one year after transplantation (visit 2). At each visit, risk factors of osteoporosis were collected, biochemical tests were performed and bone mineral density with Vertebral Fracture Assessment was assessed...
April 29, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28507888/spine-stereotactic-body-radiotherapy-indications-outcomes-and-points-of-caution
#8
Chia-Lin Tseng, Wietse Eppinga, Raphaele Charest-Morin, Hany Soliman, Sten Myrehaug, Pejman Jabehdar Maralani, Mikki Campbell, Young K Lee, Charles Fisher, Michael G Fehlings, Eric L Chang, Simon S Lo, Arjun Sahgal
STUDY DESIGN: A broad narrative review. OBJECTIVES: The objective of this article is to provide a technical review of spine stereotactic body radiotherapy (SBRT) planning and delivery, indications for treatment, outcomes, complications, and the challenges of response assessment. The surgical approach to spinal metastases is discussed with an overview of emerging minimally invasive techniques. METHODS: A comprehensive review of the literature was conducted on the techniques, outcomes, and developments in SBRT and surgery for spinal metastases...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28500828/the-impact-of-thyroid-autoimmunity-tpoab-on-bone-density-and-fracture-risk-in-postmenopausal-women
#9
Snezana P Polovina, Dragana Miljic, Sladjana Zivojinovic, Natasa Milic, Dragan Micic, Vera Popovic Brkic
OBJECTIVE: Skeletal development, linear growth, cartilage biology and bone turnover are highly dependent on the activity of thyroid hormones. Thyroid dysfunction affects the skeleton, and autoimmune thyroid disease, manifesting as a chronic inflammatory condition, may be an important contributing factor to impaired bone quality in these patients. MATERIALS AND METHODS: Measurement of TSH, FT4, TPOAb and bone mineral density and FRAX score calculations were performed in 189 postmenopausal women (110 euthyroid women and 79 women diagnosed with subclinical hypothyroidism) divided into subgroups according to the presence of TPOAb...
January 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28498071/assessment-of-malpractice-claims-due-to-spinal-epidural-abscess
#10
J Mason DePasse, Roy Ruttiman, Adam E M Eltorai, Mark A Palumbo, Alan H Daniels
OBJECTIVE Spinal epidural abscesses (SEAs) can be difficult to diagnose and may result in neurological compromise or even death. Delays in diagnosis or treatment may worsen the prognosis. While SEA presents a high risk for litigation, little is known about the medicolegal ramifications of this condition. An enhanced understanding of potential legal implications is important for practicing spine surgeons, emergency medicine physicians, and internists. METHODS The VerdictSearch database, a large legal-claims database, was queried for "epidural abscess"-related legal cases...
May 12, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28498069/an-analysis-from-the-quality-outcomes-database-part-2-predictive-model-for-return-to-work-after-elective-surgery-for-lumbar-degenerative-disease
#11
Anthony L Asher, Clinton J Devin, Kristin R Archer, Silky Chotai, Scott L Parker, Mohamad Bydon, Hui Nian, Frank E Harrell, Theodore Speroff, Robert S Dittus, Sharon E Philips, Christopher I Shaffrey, Kevin T Foley, Matthew J McGirt
OBJECTIVE Current costs associated with spine care are unsustainable. Productivity loss and time away from work for patients who were once gainfully employed contributes greatly to the financial burden experienced by individuals and, more broadly, society. Therefore, it is vital to identify the factors associated with return to work (RTW) after lumbar spine surgery. In this analysis, the authors used data from a national prospective outcomes registry to create a predictive model of patients' ability to RTW after undergoing lumbar spine surgery for degenerative spine disease...
May 12, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28497224/bone-density-microarchitecture-and-material-strength-in-chronic-kidney-disease-patients-at-the-time-of-kidney-transplantation
#12
M J Pérez-Sáez, S Herrera, D Prieto-Alhambra, L Vilaplana, X Nogués, M Vera, D Redondo-Pachón, M Mir, R Güerri, M Crespo, A Díez-Pérez, J Pascual
Bone health is assessed by bone mineral density (BMD). Other techniques such as trabecular bone score and microindentation could improve the risk of fracture's estimation. Our chronic kidney disease (CKD) patients presented worse bone health (density, microarchitecture, mechanical properties) than controls. More than BMD should be done to evaluate patients at risk of fracture. INTRODUCTION: BMD measured by dual-energy X-ray absorptiometry (DXA) is used to assess bone health in end-stage renal disease (ESRD) patients...
May 11, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28495240/risk-factors-for-pulmonary-complication-following-operative-fixation-of-spine-fractures
#13
Douglas S Weinberg, Brian Z Hedges, Jonathan E Belding, Timothy A Moore, Heather A Vallier
BACKGROUND CONTEXT: Previous studies have suggested pulmonary complications are common among patients undergoing fixation for traumatic spine fractures. This leads to prolonged hospital stay, worse functional outcomes, and increased economic burden. However, only limited prognostic information exists regarding which patients are at greatest risk for pulmonary complications. PURPOSE: To identify factors predictive of perioperative pulmonary complications in patients undergoing fixation of spine fractures...
May 8, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28486441/bone-mineral-density-in-patients-with-inherited-bone-marrow-failure-syndromes
#14
Roopa Kanakatti Shankar, Neelam Giri, Maya B Lodish, Ninet Sinaii, James C Reynolds, Sharon A Savage, Constantine A Stratakis, Blanche P Alter
BACKGROUNDPatients with inherited bone marrow failure syndromes (IBMFS) may have several risk factors for low bone mineral density (BMD). We aimed to evaluate the prevalence of low BMD in IBMFS and determine associated risk factors.METHODSPatients with IBMFS with at least one Dual Energy X-ray absorptiometry (DXA) scan were evaluated. Diagnosis of each IBMFS, Fanconi anemia (FA), dyskeratosis congenita, Diamond-Blackfan anemia, and Shwachman-Diamond syndrome, was confirmed by syndrome-specific tests. Data were gathered on age, height and clinical history...
May 9, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28483687/femoral-and-lumbar-fractures-during-rehabilitation-for-a-traumatic-spinal-cord-injury-in-osteogenesis-imperfecta-a-case-presentation
#15
Brendon S Ross, David Ripley, Anna M Ho, Leslie Rydberg
Osteogenesis imperfecta (OI) is one of the most common inherited bone disorders. These individuals are high-risk for developing fractures during their lifetime secondary to bone fragility. This case presents a female with type I OI involved in a high speed motor vehicle accident resulting in a traumatic spinal cord injury (SCI) and paraplegia. Inpatient rehabilitation was complicated by fractures of the femur and lumbar spine which impacted her level of independence upon discharge to prevent additional fractures and maintain safety...
May 5, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28473950/unusual-metastasis-of-papillary-thyroid-cancer-to-the-thoracic-spine-a-case-report-new-surgical-management-proposal-and-review-of-the-literature
#16
Ariel Takayanagi, Omid Hariri, Hammad Ghanchi, Dan E Miulli, Javed Siddiqi, Frank Vrionis, Farbod Asgarzadie
Papillary thyroid carcinoma (PTC) is significantly more common than follicular thyroid carcinoma (FTC), yet FTC has a much higher tendency to metastasize to the spinal column. We present a rare case of a metastatic thoracic spinal column lesion originating from the PTC. Thyroid carcinoma is known to be highly vascular with a significant tendency to hemorrhage during surgical resection. This increased tendency to hemorrhage leads to unanticipated intraoperative risks when the type of cancer is not diagnosed before surgical resection...
April 3, 2017: Curēus
https://www.readbyqxmd.com/read/28472175/characterization-of-3d-printing-techniques-toward-patient-specific-quality-assurance-spine-shaped-phantom-for-stereotactic-body-radiation-therapy
#17
Min-Joo Kim, Seu-Ran Lee, Min-Young Lee, Jason W Sohn, Hyong Geon Yun, Joon Yong Choi, Sang Won Jeon, Tae Suk Suh
Development and comparison of spine-shaped phantoms generated by two different 3D-printing technologies, digital light processing (DLP) and Polyjet has been purposed to utilize in patient-specific quality assurance (QA) of stereotactic body radiation treatment. The developed 3D-printed spine QA phantom consisted of an acrylic body phantom and a 3D-printed spine shaped object. DLP and Polyjet 3D printers using a high-density acrylic polymer were employed to produce spine-shaped phantoms based on CT images. Image fusion was performed to evaluate the reproducibility of our phantom, and the Hounsfield units (HUs) were measured based on each CT image...
2017: PloS One
https://www.readbyqxmd.com/read/28456854/anterior-support-reduces-the-stresses-on-the-posterior-instrumentation-after-pedicle-subtraction-osteotomy-a-finite-element-study
#18
Andrea Luca, Claudia Ottardi, Alessio Lovi, Marco Brayda-Bruno, Tomaso Villa, Fabio Galbusera
STUDY DESIGN: The investigation was based on finite-element simulations. OBJECTIVE: Pedicle subtraction osteotomy (PSO) is an effective but technical demanding surgical technique, associated with a high risk of rod failure. The present study aims at investigating the role of the anterior support in combination with PSO, with a numerical comparative analysis. METHODS: An osteotomy was simulated at the L3 level of a lumbosacral spine. An implantation of various combinations of devices for the anterior (1 or 2 cages of different material) and posterior stabilization (1 or 2 rods) was then performed...
April 29, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28451501/prevalence-and-outcomes-in-patients-undergoing-reintubation-after-anterior-cervical-spine-surgery-results-from-the-aospine-north-america-multicenter-study-on-8887-patients
#19
Narihito Nagoshi, Michael G Fehlings, Hiroaki Nakashima, Lindsay Tetreault, Jeffrey L Gum, Zachary A Smith, Wellington K Hsu, Chadi A Tannoury, Tony Tannoury, Vincent C Traynelis, Paul M Arnold, Thomas E Mroz, Ziya L Gokaslan, Mohamad Bydon, Anthony F De Giacomo, Bruce C Jobse, Eric M Massicotte, K Daniel Riew
STUDY DESIGN: A multicenter, retrospective cohort study. OBJECTIVE: To evaluate clinical outcomes in patients with reintubation after anterior cervical spine surgery. METHODS: A total of 8887 patients undergoing anterior cervical spine surgery were enrolled in the AOSpine North America Rare Complications of Cervical Spine Surgery study. Patients with or without complications after surgery were included. Demographic and surgical information were collected for patients with reintubation...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451498/a-multicenter-review-of-superior-laryngeal-nerve-injury-following-anterior-cervical-spine-surgery
#20
Zachary J Tempel, Justin S Smith, Christopher Shaffrey, Paul M Arnold, Michael G Fehlings, Thomas E Mroz, K Daniel Riew, Adam S Kanter
STUDY DESIGN: A retrospective multicenter case-series study; case report and review of the literature. OBJECTIVE: The anatomy and function of the superior laryngeal nerve (SLN) are well described; however, the consequences of SLN injury remain variable and poorly defined. The prevalence of SLN injury as a consequence of cervical spine surgery is difficult to discern as its clinical manifestations are often inconstant and frequently of a subclinical degree. A multicenter study was performed to better delineate the risk factors, prevalence, and outcomes of SLN injury...
April 2017: Global Spine Journal
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