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https://www.readbyqxmd.com/read/28323797/local-antibiotic-therapy-to-reduce-infection-after-operative-treatment-of-fractures-at-high-risk-of-infection-a-multicenter-randomized-controlled-trial-vanco-study
#1
Robert V OʼToole, Manjari Joshi, Anthony R Carlini, Clinton K Murray, Lauren E Allen, Daniel O Scharfstein, Joshua L Gary, Michael J Bosse, Renan C Castillo
A number of clinical studies in the spine literature suggest that the use of local vancomycin powder may substantially reduce surgical site infections (SSIs). These studies are primarily retrospective and observational and few focus on orthopaedic trauma patients. This study is a phase III, prospective, randomized, clinical trial to assess the efficacy of locally administered vancomycin powder in the prevention of SSI after fracture surgery. The primary goal of the VANCO Study is to compare the proportion of deep SSI 6 months after fracture fixation surgery...
April 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28322758/increased-seat-dump-angle-in-a-manual-wheelchair-is-associated-with-changes-in-thoracolumbar-lordosis-and-scapular-kinematics-during-propulsion
#2
Beth A Cloud, Kristin D Zhao, Arin M Ellingson, Ahmad Nassr, Anthony J Windebank, Kai-Nan An
OBJECTIVE: To quantify and compare spinal curvature and shoulder kinematics throughout the manual wheelchair propulsion cycle for individuals with spinal cord injury (SCI) who were seated at 2 different seat dump angles. DESIGN: Single-group, repeated-measures study. SETTING: Academic medical center. PARTICIPANTS: Twenty-eight individuals completed the telephone screening; 21 were eligible and completed the study. INTERVENTIONS: Participants' personal manual wheelchairs were modified to have seat dump angles of 0° or 14°, with a vertical backrest...
March 18, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28321993/metatropic-dysplasia-a-skeletal-dysplasia-with-challenging-airway-and-other-anesthetic-concerns
#3
Mary C Theroux, Martha Lopez, Patricia J Olszewsky, Sabina DiCindio, Lynda Arai, Colleen Ditro, Michael B Bober, Olubukola Opeyemi Olla, Tetsu Uejima, David W West, William G Mackenzie
BACKGROUND: Metatropic dysplasia is a rare form of skeletal dysplasia requiring multiple anesthetics for surgical and imaging procedures, most of which are orthopedic procedures. We provide centralized care to patients with skeletal dysplasia at our tertiary care pediatric hospital, and we were able to collect the largest number of metatropic dysplasia patients reported to date. AIM: The aim of this retrospective study was to describe and characterize the anesthetic difficulties in this high-risk population...
March 21, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28303983/frequency-of-osteopenia-and-associated-risk-factors-among-young-female-students
#4
Rabail Rani Soomro, Syed Imran Ahmed, Muhammad Khan
OBJECTIVE: To find out the frequency of osteopenia and associated risk factors among young female students. METHODS: This observational, cross-sectional study was conducted at the Dow University of Health Sciences, Karachi, from August 2011 to January 2012, and comprised young female students. Convenient sampling method was used. Age, residence, sun exposure, menstrual status, level of physical activity, exercise, vitamin D, calcium intake were variables of interest...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28303210/stereotactic-spine-radiosurgery-review-of-safety-and-efficacy-with-respect-to-dose-and-fractionation
#5
REVIEW
Michael Huo, Arjun Sahgal, David Pryor, Kristin Redmond, Simon Lo, Matthew Foote
BACKGROUND: Stereotactic body radiotherapy (SBRT) is an emerging treatment option for spinal metastases with demonstrated efficacy in the upfront, postoperative, and re-treatment settings, as well as for tumor histologies considered radioresistant. Uncertainty exists regarding the optimal dose and fractionation schedule, with single and multifraction regimens commonly utilized. METHODS: A literature search of the PubMed and Medline databases was conducted to identify papers specific to spine SBRT and the effect of varying dose/fractionation regimens on outcomes...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28301362/analysis-of-surfing-injuries-presenting-in-the-acute-trauma-setting
#6
Kevin T Jubbal, Charlie Chen, Todd Costantini, Fernando Herrera, Marek Dobke, Ahmed Suliman
BACKGROUND AND PURPOSE: Surfing is a rapidly growing major worldwide sport; however, little is understood regarding severe injuries and resulting hospital admissions. This study explores surfing-related injuries in the major surfing hub of San Diego presenting in the acute trauma setting. The purpose of this study is to address the void of information regarding severe surfing injuries in the trauma setting, including injury patterns, associated hospitalization course, and risk factors...
March 16, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28298064/radiographic-hip-anatomy-correlates-with-range-of-motion-and-symptoms-in-national-hockey-league-players
#7
Christopher M Larson, James R Ross, Andrew W Kuhn, Donnie Fuller, David M Rowley, M Russell Giveans, Rebecca M Stone, Asheesh Bedi
BACKGROUND: Hip disorders in athletes have been increasingly recognized. PURPOSE: To characterize radiographic hip anatomy for National Hockey League (NHL) players and correlate it with hip range of motion and hip symptoms and/or surgery. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: Fifty-nine professional hockey players (118 hips) with 1 NHL organization (mean age, 24.2 years; range, 18-36) prospectively underwent history and physician examination by 2 independent orthopaedic surgeons...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28296812/pedicled-vascularized-clavicular-graft-for-anterior-cervical-arthrodesis-cadaveric-feasibility-study-technique-description-and-case-report
#8
Michael A Bohl, Michael A Mooney, Joshua S Catapano, Kaith K Almefty, Mark C Preul, Steve W Chang, U Kumar Kakarla, Edward M Reece, Jay D Turner, Randall W Porter
STUDY DESIGN: Cadaveric feasibility study. OBJECTIVES: To assess the anatomic and technical feasibility of rotating a clavicular segment on a sternocleidomastoid muscle (SCM) pedicle into the ventral cervical spine using a cadaveric model and to provide the first clinical case description of performing this procedure. SUMMARY OF BACKGROUND DATA: Reconstruction of the anterior cervical spine in patients with a high risk of pseudoarthrosis may require the use of a vascularized bone graft (VBG)...
March 14, 2017: Spine
https://www.readbyqxmd.com/read/28294643/a-videofluoroscopy-based-tracking-algorithm-for-quantifying-the-time-course-of-human-intervertebral-displacements
#9
Christian Balkovec, Jim H Veldhuis, John W Baird, G Wayne Brodland, Stuart M McGill
The motions of individual intervertebral joints can affect spine motion, injury risk, deterioration, pain, treatment strategies, and clinical outcomes. Since standard kinematic methods do not provide precise time-course details about individual vertebrae and intervertebral motions, information that could be useful for scientific advancement and clinical assessment, we developed an iterative template matching algorithm to obtain this data from videofluoroscopy images. To assess the bias of our approach, vertebrae in an intact porcine spine were tracked and compared to the motions of high-contrast markers...
March 15, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28290906/-bone-metabolism-and-mineral-density-in-chronic-heart-failure
#10
V N Larina, T N Raspopova
PURPOSE: to assess the state of bone metabolism and mineral density in outpatients with chronic heart failure (CHF). MATERIAL AND METHODS: We examined 70 outpatients (30 men, 40 women, aged 56-88 years) with CHF and 40 outpatients without CHF (10 men, 30 women, aged 57-88 years). Examination included laboratory assessment, echocardiography, study of bone mineral density (BMD) in the lumbar spine and femoral neck using dual-energy X-ray absorptiometry. RESULTS: Osteoporosis was recorded in 61...
July 2016: Kardiologiia
https://www.readbyqxmd.com/read/28289103/bone-structural-changes-after-gastric-bypass-surgery-evaluated-by-hr-pqct-a-two-year-longitudinal-study
#11
Vikram Vinod Shanbhogue, René Klinkby Støving, Katrine Diemer Frederiksen, Stine Hanson, Kim Brixen, Jeppe Gram, Niklas Rye Jorgensen, Stinus Hansen
Objective, design and methods: Roux-en-Y gastric bypass (RYGB) has proved successful in attaining sustained weight loss but may lead to metabolic bone disease. To assess impact on bone mass and structure, we measured areal bone mineral density at the hip and spine by dual-energy x-ray absorptiometry, and volumetric BMD (vBMD) and bone microarchitecture at the distal radius and tibia by high-resolution peripheral quantitative CT in 25 morbidly obese subjects (15 females, 10 males) at 0, 12 and 24 months after RYGB...
March 13, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28287015/cost-consequence-analysis-of-two-different-active-flowable-hemostatic-matrices-in-spine-surgery-patients
#12
D Makhija, M Rock, S Ikeme, E Kuntze, J D Epstein, G Nicholson, J S Price, V Patel
OBJECTIVES: A recently published retrospective analysis comparing two different active flowable hemostatic matrices (FLOSEAL and SURGIFLO Kit with Thrombin) showed significantly increased resource use and complications (surgery time, risk of blood product transfusion, and amount of matrix used) with SURGIFLO use compared to FLOSEAL in major spine surgery, and also significantly increased surgical time with SURGIFLO use in severe spine surgery. This analysis was developed as a follow-up to this prior analysis, to evaluate the cost-consequence of using FLOSEAL vs SURGIFLO in major and severe spine surgery...
March 12, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28286929/cannabis-use-and-bone-mineral-density-nhanes-2007-2010
#13
Donald Bourne, Wesley Plinke, Elizabeth R Hooker, Carrie M Nielson
Cannabis use is rising in the USA. Its relationship to cannabinoid signaling in bone cells implies its use could affect bone mineral density (BMD) in the population. In a national survey of people ages 20-59, we found no association between self-reported cannabis use and BMD of the hip or spine. INTRODUCTION: Cannabis is the most widely used illegal drug in the USA, and its recreational use has recently been approved in several US states. Cannabinoids play a role in bone homeostasis. We aimed to determine the association between cannabis use and BMD in US adults...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28285031/evolution-and-complications-after-surgery-for-spine-deformation-in-patients-with-parkinson-s-disease
#14
Bouyer Benjamin, Scemama Caroline, P Roussouly, F Laouissat, I Obeid, L Boissière, F-H Parent, S Schuller, J-P Steib, H Pascal-Moussellard, P Guigui, Wolff Stéphane, Riouallon Guillaume
INTRODUCTION: Surgical treatment of spinal deformity is high risk in patients suffering from Parkinson's disease (PD). Several series have already reported a high rate of complications. However, none of these studies included more than 40 patients and none of the risk factors of complications were described. The aim of this study was to describe the rate and risk factors of revision surgery as well as the clinical outcome at the last visit in a large multicenter study of PD patients operated for spinal deformities...
March 8, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28285014/vertebral-fracture-assessment-enhancing-the-diagnosis-prevention-and-treatment-of-osteoporosis
#15
Meltem Zeytinoglu, Rajesh K Jain, Tamara J Vokes
Osteoporosis is a highly prevalent condition, resulting in significant morbidity and mortality. Nevertheless, it is frequently untreated. Vertebral fractures often do not come to clinical attention, yet, their presence is diagnostic of osteoporosis, helps to predict the risk of future fractures, and may alter the choice of pharmacotherapy. The addition of lateral spine imaging technology to the densitometer, for vertebral fracture assessment (VFA), represented a major advancement in the ability to diagnose vertebral fractures and osteoporosis...
March 8, 2017: Bone
https://www.readbyqxmd.com/read/28282479/musculoskeletal-injury-profile-of-circus-artists-a-systematic-review-of-the-literature
#16
REVIEW
H Eg Wolfenden, M Angioi
BACKGROUND: The circus arts involve a high degree of acrobatic, athletic, and aesthetic ability with extreme physical demands placed on performers. An understanding of the injury profile is required to guide prevention. AIM: To provide the first systematic review to enhance understanding of circus-related injuries and to provide a foundation for future preventative intervention. METHODS: MEDLINE, Scopus, and Web of Science were searched from conception to March 2016 using key search terms relating to circus artists and injury...
March 2017: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/28281476/objective-ergonomic-risk-assessment-of-wrist-and-spine-with-motion-analysis-technique-during-simulated-laparoscopic-cholecystectomy-in-experienced-and-novice-surgeons
#17
Twinkle Yogesh Dabholkar, Sujata Sudhir Yardi, Sanjay Narahari Oak, Sneha Ramchandani
INTRODUCTION: There is a rise in prevalence of work-related musculoskeletal disorders in surgeons performing laparoscopic surgeries due to lack of ergonomic considerations to the minimal access surgical environment. The objective of this study was to assess the physical ergonomics in experienced and novice surgeons during a simulated laparoscopic cholecystectomy. METHODOLOGY: Thirty-two surgeons participated in this study and were distributed in two groups (experienced and novices) based on the inclusion criteria...
April 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28279970/serum-sortilin-associates-with-aortic-calcification-and-cardiovascular-risk-in-men
#18
Claudia Goettsch, Hiroshi Iwata, Joshua D Hutcheson, Christopher J O'Donnell, Roland Chapurlat, Nancy R Cook, Masanori Aikawa, Pawel Szulc, Elena Aikawa
OBJECTIVE: Genome-wide association studies and preclinical studies demonstrated a role of sortilin in lipid metabolism, inflammation, and vascular calcification-all cardiovascular risk factors. We evaluated the association of serum sortilin levels with the risk of major adverse cerebrovascular and cardiovascular events (MACCE) and the severity of abdominal aortic calcification (AAC). APPROACH AND RESULTS: A cohort of community-dwelling men aged ≥50 years (n=830) was assessed...
March 9, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28276638/intravenous-zoledronic-acid-5%C3%A2-mg-on-bone-turnover-markers-and-bone-mineral-density-in-east-china-subjects-with-newly-diagnosed-osteoporosis-a-24-month-clinical-study
#19
Bo-Cheng Liang, Zhen-Yu Shi, Bo Wang, Peng Wu, Ling-Cheng Kong, Jian-Liang Yao, Chun-Wen Li, Xiao-Lin Shi
OBJECTIVE: This randomized, double-blind, placebo-controlled study assessed the necessity of early intervention, safety and efficacy of intravenous zoledronic acid 5 mg/year in East China women with newly diagnosed osteoporosis at high risk of fracture during a 24-month treatment period. METHODS: Subjects (57 [52-62] years old) were randomized 3:2 to zoledronic acid versus placebo (randomized at baseline, zoledronic acid [175 cases], placebo-zoledronic acid [110 cases])...
March 9, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28272111/disability-risk-in-pediatric-motor-vehicle-crash-occupants
#20
Andrea N Doud, Samantha L Schoell, Ashley A Weaver, Jennifer W Talton, Ryan T Barnard, John K Petty, Joel D Stitzel
BACKGROUND: Mortality rates among children in motor vehicle crashes (MVCs) are typically low, however non-fatal injuries can vary in severity by imposing differing levels of short- and long-term disability. To better discriminate the severity of non-fatal MVC-injuries, a pediatric-specific disability risk (DR) metric was created. METHODS: The National Automotive Sampling System (NASS-CDS) 2000-2011 was used to define the top 95% most common Abbreviated Injury Scale (AIS) 2+ injuries among pediatric MVC occupants...
March 8, 2017: Journal of Trauma and Acute Care Surgery
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