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https://www.readbyqxmd.com/read/28813979/towards-low-back-support-with-a-passive-biomimetic-exo-spine
#1
Matthias B Naf, Laura De Rijcke, Carlos Rodriguez Guerrero, Matthew Millard, Bram Vanderborght, Dirk Lefeber
Low-Back Pain (LBP) affects a large portion of the working population. Preventive exoskeletons have been proposed to reduce the moments on the lower back, specifically around the lumbosacral (L5/S1) joint. High correlation has been shown, between reducing the moments around the L5/S1 joint and intervertebral compression forces, which in turn have been identified as a risk factor for developing LBP. However, most passive back support exoskeletons use rigid plates or stiff beams to support the spine that limit the range of motion of the wearer...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813547/an-experimental-and-numerical-study-of-hybrid-iii-dummy-response-to-simulated-underbody-blast-impacts
#2
Karthik Somasundaram, Anil Kalra, Don Sherman, Paul Begeman, King H Yang, John M Cavanaugh
Anthropometric test devices (ATDs) such as Hybrid III dummy have been widely used in automotive crash tests to evaluate the risks of injury at different body regions. In recent years, researchers have started using automotive ATDs to study the high-speed vertical loading response caused by underbelly blast (UBB) impacts. This study analyzed the Hybrid III dummy responses to short-duration large magnitude vertical acceleration in a laboratory setup. Two unique test conditions were investigated using a horizontal sled system to simulate the UBB loading conditions...
August 16, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28811986/elderly-age-as-a-risk-factor-for-30-day-postoperative-outcomes-following-elective-anterior-cervical-discectomy-and-fusion
#3
John Di Capua, Sulaiman Somani, Jun S Kim, Kevin Phan, Nathan J Lee, Parth Kothari, Samuel K Cho
STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVE: Anterior cervical discectomy and fusion (ACDF) is one of the most commonly performed spinal procedures. Considering the high success and low complications rate of ACDF and high prevalence of age-related degeneration of the cervical spine, the rates of ACDF are expected to continually rise. The objective is to identify the association between patient age and 30-day postoperative outcomes following elective ACDF...
August 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28795472/does-ultrasound-guidance-add-accuracy-to-continuous-caudal-epidural-catheter-placements-in-neonates-and-infants
#4
Vrushali C Ponde, Vinit V Bedekar, Ankit P Desai, Kiran A Puranik
BACKGROUND: Caudo-lumbar and caudo-thoracic epidural anesthesia is an established technique that carries a low risk of dural puncture or spinal cord trauma in infants. Traditionally catheter advancement is based on external measurements. However, malpositioning of catheters are known to occur. We hypothesized that caudal-epidural catheters inserted under real-time ultrasound guidance may be more accurate than the accuracy of the measurements traditionally used for their placement. METHODS: We studied 25 patients, aged 2 days to 5 months, posted for abdominal or thoracic surgery, receiving general anesthesia followed by caudo-epidural continuous block...
August 10, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28791817/binder-syndrome-clinical-findings-and-surgical-treatment-of-18-patients-at-the-department-of-plastic-surgery-in-polanica-zdr%C3%A3-j
#5
Piotr H Drozdowski, Ireneusz Łątkowski, Mateusz G Zachara, Piotr Wójcicki
BACKGROUND: Binder syndrome (BS) is an uncommon congenital underdevelopment of the maxilla and nasal skeleton. Other clinical features include a hypoplastic or absent anterior nasal spine; a short, flat nose with short columella; an acute nasolabial angle; a convex upper lip and class III malocclusion. OBJECTIVES: The aim of the study was to outline the major characteristics of BS and to present a variety of surgical treatment methods. MATERIAL AND METHODS: The study included 18 patients treated in the authors' department from 1989 to 2013...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28780620/outcome-of-surgery-for-degenerative-lumbar-scoliosis-an-observational-study-using-the-swedish-spine-register
#6
Tian Cheng, Paul Gerdhem
PURPOSE: The outcome of surgery for degenerative lumbar scoliosis was studied in the Swedish Spine register. METHODS: 209 patients (mean age 66 years) were identified; 45 had undergone decompression and/or fusion of one segment (minor group) and 164 had undergone fusion of two or more segments, with or without decompression (major group). RESULTS: VAS back pain, VAS leg pain, ODI and EQ-5D index improved after surgery in both groups (p < 0...
August 5, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28778055/the-effect-of-the-ketogenic-diet-on-the-developing-skeleton
#7
Peter J Simm, Jillian Bicknell-Royle, Jock Lawrie, Judy Nation, Kellie Draffin, Karen G Stewart, Fergus J Cameron, Ingrid E Scheffer, Mark T Mackay
The ketogenic diet (KD) is a medically supervised, high fat, low carbohydrate and restricted protein diet which has been used successfully in patients with refractory epilepsy. Only one published report has explored its effect on the skeleton. We postulated that the KD impairs skeletal health parameters in patients on the KD. Patients commenced on the KD were enrolled in a prospective, longitudinal study, with monitoring of Dual-energy X-ray absorptiometry (DXA) derived bone parameters including bone mineral content and density (BMD)...
July 26, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28770402/kinematic-efficacy-of-supplemental-anterior-lumbar-interbody-fusion-at-lumbosacral-levels-in-thoracolumbosacral-deformity-correction-with-and-without-pedicle-subtraction-osteotomy-at-l3-an-in-vitro-cadaveric-study
#8
Benny T Dahl, Jonathan A Harris, Manasa Gudipally, Mark Moldavsky, Saif Khalil, Brandon S Bucklen
PURPOSE: Pedicle subtraction osteotomy (PSO) is performed to treat rigid, sagittal spinal deformities, but high rates of implant failure are reported. Anterior lumbar interbody fusion has been proposed to reduce this risk, but biomechanical investigation is lacking. The goal of this study was to quantify the (1) destabilizing effects of a lumbar osteotomy and (2) contribution of anterior lumbar interbody fusion (ALIF) at the lumbosacral junction as recommended in literature. METHODS: Fourteen fresh human thoracolumbosacral spines (T12-S1) were tested in flexion-extension (FE), lateral bending (LB), and axial rotation (AR)...
August 2, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28767569/visual-loss-due-to-optic-nerve-infarction-and-central-retinal-artery-occlusion-after-spine-surgery-in-the-prone-position-a-case-report
#9
Soo Hee Lee, Inyoung Chung, Dae Seob Choi, Il-Woo Shin, Sunmin Kim, Sebin Kang, Ji-Yoon Kim, Young-Kyun Chung, Ju-Tae Sohn
RATIONALE: Visual loss after spine surgery in the prone position is a serious complication. Several cases of central retinal artery occlusion with ophthalmoplegia after spine surgery have been reported in patients with ophthalmic arteries fed by the internal carotid artery (ICA) in a normal manner. PATIENT CONCERNS: A 74-year-old man developed visual loss after undergoing a spinal decompression and fusion operation in the prone position that lasted approximately 5 hours...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28766739/serum-levels-of-a-cathepsin-k-generated-periostin-fragment-predict-incident-low-trauma-fractures-in-postmenopausal-women-independently-of-bmd-and-frax
#10
Nicolas Bonnet, Emmanuel Biver, Thierry Chevalley, René Rizzoli, Patrick Garnero, Serge L Ferrari
Periostin is a matricellular protein involved in bone formation and bone matrix organization, but it is also produced by other tissues. Its circulating levels have been weakly associated with bone microstructure and prevalent fractures, possibly because periostin measured by the current commercial assays does not specifically reflect bone metabolism. In this context, we developed a new ELISA for a periostin fragment resulting from cathepsin K digestion (K-Postn). We hypothesized that circulating K-Postn levels could be associated with bone fragility...
August 2, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28764702/characterisation-of-the-correlation-between-standing-lordosis-and-degenerative-joint-disease-in-the-lower-lumbar-spine-in-women-and-men-a-radiographic-study
#11
Kelvin J Murray, Michael R Le Grande, Arantxa Ortega de Mues, Michael F Azari
BACKGROUND: Degenerative joint disease (DJD) in the lumbar spine is a common condition that is associated with chronic low back pain. Excessive loading of lumbar joints is a risk factor for DJD. Changes in lumbar lordosis significantly redistribute the forces of weight-bearing on the facet joints and the intervertebral discs. However, the relationship between lumbar lordosis and DJD has not been characterized in men and women. METHODS: We characterised the correlation between standing lumbar lordosis and DJD in standing radiographic images from 301 adult female and male chiropractic patients...
August 1, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28763410/risk-factors-for-prolonged-opioid-use-following-spine-surgery-and-the-association-with-surgical-intensity-among-opioid-naive-patients
#12
Andrew J Schoenfeld, Kenneth Nwosu, Wei Jiang, Allan L Yau, Muhammad Ali Chaudhary, Rebecca E Scully, Tracey Koehlmoos, James D Kang, Adil H Haider
BACKGROUND: There is a growing concern that the use of prescription opioids following surgical interventions, including spine surgery, may predispose patients to chronic opioid use and abuse. We sought to estimate the proportion of patients using opioids up to 1 year after discharge following common spinal surgical procedures and to identify factors associated with sustained opioid use. METHODS: This study utilized 2006 to 2014 data from TRICARE insurance claims obtained from the Military Health System Data Repository...
August 2, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28758968/middle-cerebral-artery-stroke-as-amusement-park-injury-case-report-and-review-of-the-literature
#13
Abby Baumgartle, Laura Wolfe, Vinay Puri, Karen Moeller, Salvatore Bertolone, Ashok Raj
Strokes as amusement park injuries are rare, but have been reported in the literature. Only about 20 cases of cerebrovascular accidents after amusement park visits have been described. We report a healthy 12-year-old boy who presented with facial droop, slurred speech, and inability to use his right arm after riding roller coasters at a local amusement park. He was evaluated and found to have a left middle cerebral artery (MCA) infarction. The patient was treated with anticoagulants and has recovered with no major residual symptoms...
July 31, 2017: Children
https://www.readbyqxmd.com/read/28755782/romosozumab-sclerostin-monoclonal-antibody-versus-teriparatide-in-postmenopausal-women-with-osteoporosis-transitioning-from-oral-bisphosphonate-therapy-a-randomised-open-label-phase-3-trial
#14
Bente L Langdahl, Cesar Libanati, Daria B Crittenden, Michael A Bolognese, Jacques P Brown, Nadia S Daizadeh, Eva Dokoupilova, Klaus Engelke, Joel S Finkelstein, Harry K Genant, Stefan Goemaere, Lars Hyldstrup, Esteban Jodar-Gimeno, Tony M Keaveny, David Kendler, Peter Lakatos, Judy Maddox, Jorge Malouf, Fabio E Massari, Jose Fernando Molina, Maria Rosa Ulla, Andreas Grauer
BACKGROUND: Previous bisphosphonate treatment attenuates the bone-forming effect of teriparatide. We compared the effects of 12 months of romosozumab (AMG 785), a sclerostin monoclonal antibody, versus teriparatide on bone mineral density (BMD) in women with postmenopausal osteoporosis transitioning from bisphosphonate therapy. METHODS: This randomised, phase 3, open-label, active-controlled study was done at 46 sites in North America, Latin America, and Europe...
July 26, 2017: Lancet
https://www.readbyqxmd.com/read/28748740/the-use-of-fluoroscopic-guided-percutaneous-pedicle-screws-in-the-upper-thoracic-spine-t1-t6-is-it-safe
#15
Mun Keong Kwan, Chee Kidd Chiu, Chris Yin Wei Chan, Reza Zamani, Nils Hansen-Algenstaedt
PURPOSE: This study analysed the accuracy and safety of the fluoroscopic guided percutaneous screws in the upper thoracic vertebrae (T1-T6). METHODS: Computed tomography scans from 74 patients were retrospectively evaluated between January 2008 and December 2012. Pedicle perforations were classified by two types of grading systems. For medial, lateral, superior and inferior perforations: grade 0 - no violation; grade 1 - <2 mm; grade 2 - 2-4 mm and grade 3 - >4 mm...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28748385/effect-of-implementation-of-guidelines-on-assessment-and-diagnosis-of-vertebral-fractures-in-patients-older-than-50%C3%A2-years-with-a-recent-non-vertebral-fracture
#16
R Y van der Velde, S P G Bours, C E Wyers, W F Lems, P P M M Geusens, J P W van den Bergh
We evaluated the impact of a new Dutch guideline on systematic implementation of densitometric Vertebral Fracture Assessment (VFA) in patients with a recent non-vertebral fracture. Systematic implementation resulted in a significant increase of VFA, diagnosis of vertebral fractures (VFs), and percentage of patients eligible for treatment. INTRODUCTION: VFs are underdiagnosed although they are important predictors of fracture risk, independent of age and bone mineral density (BMD). The Dutch guideline on osteoporosis and fracture prevention recommends VFA in all patients aged >50 years with a recent non-VF...
July 26, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28742737/the-azygos-vein-is-at-potential-risk-of-injury-from-malpositioning-of-left-thoracic-pedicle-screw-in-thoracic-adolescent-idiopathic-scoliosis-patients
#17
Jun Jiang, Bang-Ping Qian, Yong Qiu, Bin Wang, Yang Yu, Ze-Zhang Zhu
STUDY DESIGN: A computed tomography study. OBJECTIVE: To evaluate the changed position of azygos vein in patients with thoracic adolescent idiopathic scoliosis (AIS) and to analyze the potential risk of injury of azygos vein from thoracic pedicle screw placement in these patients. SUMMARY OF BACKGROUND DATA: It has been widely recognized that the anatomic positions of structures adjacent to the vertebrae may change in patients with AIS. To date, no study had evaluated such change of azygos vein in patients with AIS...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28739474/traumatic-subaxial-cervical-facet-subluxation-and-dislocation-epidemiology-radiographic-analyses-and-risk-factors-for-spinal-cord-injury
#18
Ryan D Quarrington, Claire F Jones, Petar Tcherveniakov, Jillian M Clark, Simon J I Sandler, Yu Chao Lee, Shabnam Torabiardakani, John J Costi, Brian J C Freeman
BACKGROUND CONTEXT: Distractive-flexion injuries (DFIs) of the subaxial cervical spine are major contributors to spinal cord injury (SCI). Prompt assessment and early intervention of DFIs associated with SCI is crucial to optimize patient outcome; however, neurological examination of patients with subaxial cervical injury is often difficult, as patients commonly present with reduced levels of consciousness. Therefore, it is important to establish potential associations between injury epidemiology and radiographic features, and neurological involvement...
July 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28739045/filamin-b-the-next-hotspot-in-skeletal-research
#19
REVIEW
Qiming Xu, Nan Wu, Lijia Cui, Zhihong Wu, Guixing Qiu
Filamin B (FLNB) is a large dimeric actin-binding protein which crosslinks actin cytoskeleton filaments into a dynamic structure. Up to present, pathogenic mutations in FLNB are solely found to cause skeletal deformities, indicating the important role of FLNB in skeletal development. FLNB-related disorders are classified as spondylocarpotarsal synostosis (SCT), Larsen syndrome (LS), atelosteogenesis (AO), boomerang dysplasia (BD), and isolated congenital talipes equinovarus, presenting with scoliosis, short-limbed dwarfism, clubfoot, joint dislocation and other unique skeletal abnormalities...
July 20, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28736691/prevalence-and-risk-factors-of-osteoporosis-among-jordanian-postmenopausal-women-attending-the-national-center-for-diabetes-endocrinology-and-genetics-in-jordan
#20
Dana Hyassat, Taghreed Alyan, Hashem Jaddou, Kamel M Ajlouni
To assess the prevalence of osteoporosis and osteopenia among Jordanian postmenopausal women attending the National Center for Diabetes, Endocrinology, and Genetics (NCDEG), and to determine the potential associated risk factors. A cross-sectional study was conducted at (NCDEG) in Amman, Jordan. A total of 1079 Jordanian postmenopausal women aged between 45 and 84 years were included in this study that was conducted during the period between April 2013 and December 2014. All patients underwent bone mineral density measurement through dual-energy X-ray absorptiometry (DEXA) scan...
2017: BioResearch Open Access
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