keyword
MENU ▼
Read by QxMD icon Read
search

high risk spine

keyword
https://www.readbyqxmd.com/read/29783868/low-bone-mineral-density-in-ambulatory-persons-with-cerebral-palsy-a-systematic-review
#1
Cindy T R Mus-Peters, Bionka M A Huisstede, Suzie Noten, Minou W M G C Hitters, Wilma M A van der Slot, Rita J G van den Berg-Emons
PURPOSE: Non-ambulatory persons with cerebral palsy are prone to low bone mineral density. In ambulatory persons with cerebral palsy, bone mineral density deficits are expected to be small or absent, but a consensus conclusion is lacking. In this systematic review bone mineral density in ambulatory persons with cerebral palsy (Gross Motor Function Classification Scales I-III) was studied. MATERIALS AND METHODS: Medline, Embase, and Web of Science were searched. According to international guidelines, low bone mineral density was defined as Z-score ≤ -2...
May 22, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29776756/sex-hormone-binding-globulin-is-a-biomarker-associated-with-nonvertebral-fracture-in-men-on-dialysis-therapy
#2
Jasna Aleksova, Phillip Wong, Robert McLachlan, Kay Weng Choy, Peter R Ebeling, Frances Milat, Grahame J Elder
Gonadal hormones impact bone health and higher values of sex hormone-binding globulin (SHBG) have been independently associated with fracture risk in men without chronic kidney disease. People with chronic kidney disease have a greatly increased fracture risk, and gonadal dysfunction is common in men receiving dialysis treatment. Nevertheless, in these men the effect of gonadal steroids and SHBG on bone mineral density (BMD) and fracture risk is unknown. Here we investigate relationships between gonadal steroids, SHBG, BMD and fracture in men on long-term dialysis therapy, awaiting kidney or simultaneous pancreas kidney transplantation...
May 15, 2018: Kidney International
https://www.readbyqxmd.com/read/29775762/aortic-vascular-calcification-is-inversely-associated-with-the-trabecular-bone-score-in-patients-receiving-dialysis
#3
Jasna Aleksova, Samantha Kurniawan, Mirna Vucak-Dzumhur, Peter Kerr, Peter R Ebeling, Frances Milat, Grahame J Elder
INTRODUCTION: Progressive chronic kidney disease (CKD) confers a marked increase in risk for vascular calcification, cardiovascular disease, fracture and mortality, with likely contributing factors including dysregulated bone metabolism and mineral homeostasis. In general population studies, increased vascular calcification is directly related to mortality and inversely related to bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA). In patients with CKD, abnormalities in turnover, mineralization and bone volume, reduce the ability of DXA to predict fracture...
May 15, 2018: Bone
https://www.readbyqxmd.com/read/29774402/subtrochanteric-and-diaphyseal-femoral-fractures-in-hypophosphatasia-not-atypical-at-all
#4
F Genest, L Seefried
Risk for subtrochanteric and diaphyseal femoral fractures is considered increased in patients with hypophosphatasia (HPP). Evaluating a large cohort of HPP patients, we could for the first time quantify the prevalcence and identify both morphometric features as well as predisposing factors for this complication of severe HPP. INTRODUCTION: Subtrochanteric and diaphyseal femoral fractures have been associated with both, long-term antiresorptive treatment and metabolic bone disorders, specifically Hypophosphatasia (HPP)...
May 17, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29774400/cost-effectiveness-of-osteoporosis-screening-strategies-for-hip-fracture-prevention-in-older-chinese-people-a-decision-tree-modeling-study-in-the-mr-os-and-ms-os-cohort-in-hong-kong
#5
Y Su, F T T Lai, B H K Yip, J C S Leung, T C Y Kwok
Despite the high costs of hip fracture, many governments provide limited support for osteoporosis screening. We demonstrated that osteoporosis screening by dual-energy X-ray absorptiometry (DXA) with or without pre-screening by Fracture Risk Assessment Tool (FRAX) or calcaneal ultrasound are more cost-effective than no screening in Chinese people aged 65 or over in Hong Kong. INTRODUCTION: To examine the cost-effective potential osteoporosis screening strategies for hip fracture prevention in Hong Kong...
May 17, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29772370/does-nasal-carriage-of-staphylococcus-aureus-increase-the-risk-of-post-operative-infections-after-elective-spine-surgery-do-most-infections-occur-in-carriers
#6
Owoicho Adogwa, Victoria D Vuong, Aladine A Elsamadicy, Daniel T Lilly, Shyam A Desai, Syed Khalid, Joseph Cheng, Carlos A Bagley
BACKGROUND: Wound infections following adult spinal deformity surgery place a high toll on patients, providers, and the healthcare system. Staphylococcus aureus is a common cause of postoperative wound infections, and nasal colonization by this organism may be an important factor development of surgical site infections (SSI's). The aim is to investigate whether post-operative surgical site infections after elective spine surgery occur at a higher rate in patients with Methicillin-Resistant Staphylococcus Aureus (MRSA) nasal colonization...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29770769/ct-fluoroscopy-guided-percutaneous-osteoplasty-with-or-without-radiofrequency-ablation-in-the-treatment-of-painful-extraspinal-and-spinal-bone-metastases-technical-outcome-and-complications-in-29-patients
#7
Caroline A Burgard, Julien Dinkel, Frederik Strobl, Philipp M Paprottka, Nicolai Schramm, Maximilian Reiser, Christoph G Trumm
PURPOSE: We aimed to assess the safety and technical outcome of computed tomography (CT) fluoroscopy-guided osteoplasty with or without prior percutaneous radiofrequency ablation (RFA) in patients with painful osteolyses. METHODS: We performed a retrospective analysis of 29 patients with painful extraspinal and spinal osteolyses (16 women, 13 men; 63.1±14.4 years) who underwent CT fluoroscopy-guided osteoplasty (10-20 mAs tube current) with or without RFA (26 and 14 lesions, respectively), in 33 consecutive procedures from 2002 to 2016...
May 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29770222/recurrent-vertebral-fractures-in-a-young-adult-a-closer-look-at-bone-health-in-type-1-diabetes-mellitus
#8
Eleanor P Thong, Sarah Catford, Julie Fletcher, Phillip Wong, Peter J Fuller, Helena Teede, Frances Milat
The association between type 1 diabetes mellitus (T1DM) and bone health has garnered interest over the years. Fracture risk is known to be increased in individuals with T1DM, although bone health assessment is not often performed in the clinical setting. We describe the case of a 21-year-old male with longstanding T1DM with multilevel vertebral fractures on imaging, after presenting with acute back pain without apparent trauma. Dual-energy X-ray absorptiometry (DXA) revealed significantly reduced bone mineral density at the lumbar spine and femoral neck...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29768627/tsh-receptor-antibodies-may-prevent-bone-loss-in-pre-and-postmenopausal-women-with-graves-disease-and-graves-orbitopathy
#9
Mira Siderova, Kiril Hristozov, Aleksandra Tsukeva
OBJECTIVE: Thyrotoxicosis is established risk factor for osteoporosis due to increased bone turnover. Glucocorticoids often administered for Graves' orbitopathy (GO) have additional negative effect on bone mineral density (BMD). Our aim was to examine the influence of thyroid hormones, TSH, TSH-receptor antibodies (TRAb) and glucocorticoid treatment on bone in women with Graves' thyrotoxicosis and Graves' orbitopathy (GO). SUBJECTS AND METHODS: Forty seven women with Graves' disease, mean age 55...
March 2018: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29766142/improving-life-expectancy-a-broken-neck-doesn-t-have-to-be-a-terminal-diagnosis-for-the-elderly
#10
Laura N Godat, Leslie M Kobayashi, David C Chang, Raul Coimbra
Background: Elderly patients with cervical spine fractures require optimal care. Treatment with a cervical collar or halo instead of surgical fixation may increase mortality. This investigation intends to describe the life expectancy after injury and evaluate the impact of surgical intervention on mortality. Methods: Patients ≥65 years, with traumatic cervical spine fractures without cord injury were identified in the 1995-2009 California Office of Statewide Health and Planning database...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29765790/direct-posterior-bipolar-cervical-facet-radiofrequency-rhizotomy-a-simpler-and-safer-approach-to-denervate-the-facet-capsule
#11
Ovidiu Palea, Haroon M Andar, Ramon Lugo, Michelle Granville, Robert E Jacobson
Radiofrequency cervical rhizotomy has been shown to be effective for the relief of chronic neck pain, whether it be due to soft tissue injury, cervical spondylosis, or post-cervical spine surgery. The target and technique have traditionally been taught using an oblique approach to the anterior lateral capsule of the cervical facet joint. The goal is to position the electrode at the proximal location of the recurrent branch after it leaves the exiting nerve root and loops back to the cervical facet joint. The standard oblique approach to the recurrent nerve requires the testing of both motor and sensory components to verify the correct position and ensure safety so as to not damage the slightly more anterior nerve root...
March 14, 2018: Curēus
https://www.readbyqxmd.com/read/29762340/external-validation-of-the-adult-spinal-deformity-asd-frailty-index-asd-fi-in-the-scoli-risk-1-patient-database
#12
Emily K Miller, Lawrence G Lenke, Brian J Neuman, Daniel M Sciubba, Khaled M Kebaish, Justin S Smith, Yong Qiu, Benny T Dahl, Ferran Pellisé, Yukihiro Matsuyama, Leah Y Carreon, Michael G Fehlings, Kenneth M Cheung, Stephen Lewis, Mark B Dekutoski, Frank J Schwab, Oheneba Boachie-Adjei, Hossein Mehdian, Shay Bess, Christopher I Shaffrey, Christopher P Ames
STUDY DESIGN: Analysis of a prospective multicenter database. OBJECTIVE: To assess the ability of the recently created Adult Spinal Deformity (ASD) Frailty Index (ASD-FI) to predict odds of major complications and length of hospital stay for patients who had more severe preoperative deformity and underwent more invasive ASD surgery compared with patients in the database used to create the index. SUMMARY OF BACKGROUND DATA: Accurate preoperative estimates of risk are necessary given the high complication rates currently associated with ASD surgery...
May 14, 2018: Spine
https://www.readbyqxmd.com/read/29758361/bone-accrual-in-oligo-amenorrheic-athletes-eumenorrheic-athletes-and-non-athletes
#13
Vibha Singhal, Karen Campoverde Reyes, Brooke Pfister, Kathryn Ackerman, Meghan Slattery, Katherine Cooper, Alexander Toth, Nupur Gupta, Mark Goldstein, Kamryn Eddy, Madhusmita Misra
BACKGROUND: Mechanical loading improves bone mineral density (BMD) and strength while decreasing fracture risk. Cross-sectional studies show that exercise advantage is lost in oligo-amenorrheic athletes (OA). Longitudinal studies examining the opposing effects of exercise and hypogonadism on bone are lacking in adolescents/young adults. OBJECTIVE: Evaluate differences in bone accrual over 12 months in OA, eumenorrheic athletes (EA) and non-athletes (NA). We hypothesized that bone accrual would be lower in OA than EA and NA, with differences most pronounced at non-weight bearing trabecular sites...
May 11, 2018: Bone
https://www.readbyqxmd.com/read/29757778/a-contemporary-analysis-of-medicolegal-issues-in-obstetric-anesthesia-between-2005-and-2015
#14
Vesela P Kovacheva, Ethan Y Brovman, Penny Greenberg, Ellen Song, Arvind Palanisamy, Richard D Urman
BACKGROUND: Detailed reviews of closed malpractice claims have provided insights into the most common events resulting in litigation and helped improve anesthesia care. In the past 10 years, there have been multiple safety advancements in the practice of obstetric anesthesia. We investigated the relationship among contributing factors, patient injuries, and legal outcome by analyzing a contemporary cohort of closed malpractice claims where obstetric anesthesiology was the principal defendant...
May 10, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29743793/bone-health-and-impact-of-tenofovir-treatment-in-men-with-hepatitis-b-related-chronic-liver-disease
#15
Kattiparambil G Sajith, Nitin Kapoor, Sahana Shetty, Ashish Goel, Uday Zachariah, Chundamannil E Eapen, Thomas V Paul
Background: Chronic Liver Disease (CLD) has been shown to have an adverse impact on bone health. Hepatitis-B related CLD and its treatment with tenofovir may have additional effects on skeleton. Objective: To study the impact of HBV related CLD and its treatment with Tenofovir on bone health in Indian subjects. Methods: This cross sectional study included men (18-60 years) and comprised of three groups: Group-1 was treatment naïve HBV related CLD ( n  = 79), Group-2 those with HBV related CLD on tenofovir for at least 1 year ( n  = 136), Group-3 age, sex and Body Mass Index (BMI) matched healthy controls ( n  = 58)...
March 2018: Journal of Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/29734510/association-between-sarcopenia-and-osteoporosis-in-chronic-liver-disease
#16
Manabu Hayashi, Kazumichi Abe, Masashi Fujita, Ken Okai, Atsushi Takahashi, Hiromasa Ohira
AIM: Sarcopenia and osteoporosis are important complications in chronic liver disease (CLD). The aim of this study was to investigate the relationship between sarcopenia and osteoporosis in patients with CLD. METHODS: We retrospectively investigated the relationship between sarcopenia and osteoporosis in 112 CLD patients (57 males and 55 females), including 40 cirrhotic patients (36%), by measuring the appendicular skeletal muscle mass index (ASMI) using bio-impedance analysis...
May 7, 2018: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/29730704/normal-bone-microstructure-and-density-but-worse-physical-function-in-older-women-treated-with-selective-serotonin-reuptake-inhibitors-a-cross-sectional-population-based-study
#17
Berit Larsson, Dan Mellström, Lisa Johansson, Anna G Nilsson, Mattias Lorentzon, Daniel Sundh
Depression in the elderly is today often treated with selective serotonin reuptake inhibitors (SSRIs) because of their favorable adverse effect profile. However, treatment with SSRIs is associated with increased risk of fractures. Whether this increased risk depends on reduced bone strength or increased fall risk due to reduced physical function is not certain. The aim was therefore to investigate if treatment with SSRIs is associated with impaired bone microstructure, bone density, or physical function in older women...
May 5, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29730393/virtual-immersive-gaming-to-optimize-recovery-vigor-in-low-back-pain-a-phase-ii-randomized-controlled-trial
#18
Christopher R France, James S Thomas
The virtual immersive gaming to optimize recovery (VIGOR) study is a randomized controlled trial of the effects of virtual reality games to encourage lumbar spine flexion among individuals with chronic low back pain and fear of movement. Whereas traditional graded activity or graded exposure therapies for chronic low back pain have high attrition and poor long-term efficacy, we believe that virtual reality games have distinct advantages that can enhance adherence and clinical outcomes. First, they are engaging and enjoyable activities that can distract from pain and fear of harm...
May 3, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29730177/ankyrins-roles-in-synaptic-biology-and-pathology
#19
REVIEW
Katharine R Smith, Peter Penzes
Ankyrins are broadly expressed adaptors that organize diverse membrane proteins into specialized domains and link them to the sub-membranous cytoskeleton. In neurons, ankyrins are known to have essential roles in organizing the axon initial segment and nodes of Ranvier. However, recent studies have revealed novel functions for ankyrins at synapses, where they organize and stabilize neurotransmitter receptors, modulate dendritic spine morphology and control adhesion to the presynaptic site. Ankyrin genes have also been highly associated with a range of neurodevelopmental and psychiatric diseases, including bipolar disorder, schizophrenia and autism, which all demonstrate overlap in their genetics, mechanisms and phenotypes...
May 3, 2018: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/29729461/high-risk-surgical-maneuvers-for-impending-true-positive-intraoperative-neurologic-monitoring-alerts-experience-in-3139-consecutive-spine-surgeries
#20
Shujie Wang, Qiyi Li, Jie Zhu, Jianxiong Shen, Ye Tian, Yong Hu, Jianguo Zhang
BACKGROUND: Intraoperative neurologic monitoring (IONM) has become an essential component for decreasing the incidence of spinal cord injury during many spine surgeries. Many high-risk surgical maneuvers that result in significant IONM alerts have not been reported systematically. Our objective in this study was to thoroughly summarize some common high-risk surgical points associated with IONM alerts in various spine surgeries. METHODS: A total of 62 patients with true-positive IONM alerts from 3139 spine surgeries were enrolled between November 2010 and April 2017...
May 2, 2018: World Neurosurgery
keyword
keyword
80748
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"