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https://www.readbyqxmd.com/read/29327560/-research-progress-on-reatment-of-unstable-atlas-fracture-with-single-segment-fixation-by-transoral-approach
#1
REVIEW
Li-Ran Wang, Liu-Jun Zhao, Wei-Hu Ma
As a common type of fracture in cervical, atlas fracture is frequently unstable due to its special anatomical structure. In a previous treatment, external fixation was likely to bring low bony union rate and long-term neck pain, while occipito-cervical fusion and atlantoaxial fusion sacrifice range of motion in cervical spine. Reduction and single section fixation of atlas by anterior lateral mass screws through the transoral approach were reported by some scholars, and the retrospective study demonstrated the high healing rate, reservation of cervical ROM and less bleeding...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29325137/review-of-neurosurgery-medical-professional-liability-claims-in-the-united-states
#2
Aladine A Elsamadicy, Amanda R Sergesketter, Michael D Frakes, Shivanand P Lad
BACKGROUND: Due to disparaging costs and rates of malpractice claims in neurosurgery, there has been significant interest in identifying high-risk specialties, types of malpractice claims, and characteristics of claim-prone physicians. OBJECTIVE: To characterize the malpractice claims against neurosurgeons. METHODS: This was a comprehensive analysis of all malpractice liability claims involving a neurosurgeon as the primary defendant, conducted using the Physician Insurers Association of America Data Sharing Project from January 1, 2003 and December 31, 2012...
January 8, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29322222/urinary-pentosidine-levels-negatively-associates-with-trabecular-bone-scores-in-patients-with-type-2-diabetes-mellitus
#3
Y J Choi, S Y Ock, Y Jin, J S Lee, S H Kim, Y -S Chung
Pentosidine levels were higher in diabetic patients with vertebral fractures. Trabecular bone scores were negatively associated with pentosidine levels in diabetic patients only. Our results provide further evidence that AGEs are associated with the pathogenesis of bone fragility in patients with T2DM. INTRODUCTION: Type 2 diabetes mellitus (T2DM) is associated with fracture risk. Pentosidine, an advanced glycation end product (AGE), is associated with prevalent vertebral fractures (VFs) in patients with T2DM...
January 10, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29321098/spondylodiscitis-diagnosis-and-treatment-options
#4
Christian Herren, Norma Jung, Miguel Pishnamaz, Marianne Breuninger, Jan Siewe, Rolf Sobottke
BACKGROUND: A recent population-based study from Denmark showed that the incidence of spondylodiscitis rose from 2.2 to 5.8 per 100 000 persons per year over the period 1995-2008; the age-standardized incidence in Germany has been estimated at 30 per 250 000 per year on the basis of data from the Federal Statistical Office (2015). The early diagnosis and treatment of this condition are essential to give the patient the best chance of a good outcome, but these are often delayed because it tends to present with nonspecific manifestations, and fever is often absent...
December 25, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29318009/assessment-of-osteoporosis-using-the-frax-method-and-the-importance-of-vitamin-d-levels-in-copd-patients
#5
Ceyda Anar, Melike Yüksel Yavuz, Filiz Güldaval, Yelda Varol, Dilek Kalenci
Background: The aim of this paper was to evaluate the availability of FRAX for assessing osteoporosis risk, and to demonstrate the importance of vitamin D levels in COPD patients. Methods: Fourty-six males who fulfilled the COPD diagnostic criteria defined by GOLD were included. Age, race, BMI, physical activity frequency, smoking and dietary habits, age at COPD diagnosis, disease duration, fractures history, and medications use were determined. Levels of 25(OH)D were detected...
2018: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29316474/spinal-versus-general-anesthesia-for-lumbar-spine-surgery-in-high-risk-patients-perioperative-hemodynamic-stability-complications-and-costs
#6
Michael Finsterwald, Marco Muster, Mazda Farshad, Andrea Saporito, Muriel Brada, José A Aguirre
OBJECTIVE: More stable perioperative hemodynamic conditions, lower costs and a lower perioperative complication rate were reported in young healthy patients undergoing lumbar spine surgery in spinal anesthesia (SA) compared to general anesthesia (GA). However, the benefits of SA in high risk patients (ASA≥II suffering from cardiovascular and/or pulmonary pathologies) undergoing this surgery are unclear. Our objective was to analyze whether SA leads to an improved perioperative hemodynamic stability and to a more cost-effective management compared to GA in high risk patients undergoing this surgery...
January 6, 2018: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29314651/prevalence-and-predictors-of-asymptomatic-vertebral-fractures-in-inflammatory-myositis
#7
Latika Gupta, Able Lawrence, Sukesh Edavalath, Ramnath Misra
AIM: To assess the frequency and risk factors of asymptomatic vertebral fractures in inflammatory myositis. PATIENTS AND METHODS: Dorsal and lumbar spine lateral radiographs were taken for adults with inflammatory myositis and scored using Genant's semi-quantitative technique. Demographic data, weight, height, postmenopausal status, duration of corticosteroid use, drug intake, co-morbidities and past history of fractures were recorded. Bone mineral density (BMD) was assessed using dual-energy X-ray absorptiometry (DEXA)...
January 5, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29301014/pedicled-vascularized-bone-grafts-for-posterior-occipitocervical-and-cervicothoracic-fusion-a-cadaveric-feasibility-study
#8
Michael A Bohl, Michael A Mooney, Joshua S Catapano, Kaith K Almefty, Jay D Turner, Steve W Chang, Mark C Preul, Edward M Reece, U Kumar Kakarla
BACKGROUND: Arthrodesis is critical for achieving favorable outcomes in reconstructive spine surgery. Vascularized bone grafts (VBGs) have been successfully used to augment fusion rates in a variety of skeletal pathologies, and pedicled VBG has numerous advantages over free transfer VBG. Pedicled VBG has not previously been described for the posterior occipitocervicothoracic spine. OBJECTIVE: To identify, describe, and assess potential donor sites for pedicled VBGs from occiput to T12 using a cadaver model and to describe important technical considerations for graft harvest and placement...
December 30, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29300251/do-preoperative-corticosteroid-injections-increase-the-risk-for-infections-or-wound-healing-problems-after-spine-surgery-a-swiss-prospective-multicenter-cohort-study
#9
Mazda Farshad, Jakob M Burgstaller, Ulrike Held, Johann Steurer, Cyrill Dennler
STUDY DESIGN: Prospective multi-center cohort study. OBJECTIVES: This study evaluates the risk for surgical site infections (SSI) or wound healing problems (WHP) in patients who underwent corticosteroid injection prior to lumbar decompression surgery. SUMMARY OF BACKGROUND DATA: Corticosteroid injections are often used for the treatment of the degenerated spine. However, their well-known immunosuppressive effects could increase the risk for local infections, particularly if a surgical intervention follows the injection rapidly...
January 3, 2018: Spine
https://www.readbyqxmd.com/read/29287746/the-importance-of-data-structure-in-statistical-analysis-of-dendritic-spine-morphology
#10
Veerle Paternoster, Anto P Rajkumar, Jens Randel Nyengaard, Anders Dupont Børglum, Jakob Grove, Jane Hvarregaard Christensen
BACKGROUND: Dendritic spine morphology is heterogeneous and highly dynamic. To study the changing or aberrant morphology in test setups, often spines from several neurons from a few experimental units e.g. mice or primary neuronal cultures are measured. This strategy results in a multilevel data structure, which, when not properly addressed, has a high risk of producing false positive and false negative findings. METHODS: We used mixed-effects models to deal with data with a multilevel data structure and compared this method to analyses at each level...
December 26, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29285559/pressure-induced-end-plate-fracture-in-the-porcine-spine-is-the-annulus-fibrosus-susceptible-to-damage
#11
Chelsea R Snow, Maxine Harvey-Burgess, Brigitte Laird, Stephen H M Brown, Diane E Gregory
PURPOSE: To determine if the mechanical properties of the annulus fibrosus (AF) are altered following end-plate fracture. Vertebral fractures, particularly those in the growth plate, are relatively common among adolescents. What is unclear is whether or not these fractures are also associated with concomitant damage to the intervertebral disc (IVD), in particular the AF. METHODS: The current study employed a high-rate IVD pressurization model to create growth plate fractures in the porcine cervical spine...
December 28, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29284890/a-safe-regional-technique-in-a-high-risk-patient-cervical-plexus-blockage
#12
Ayhan Kaydu, Ebru Tarıkçı Kılıç, Erhan Gökçek, Mehmet Salim Akdemir
Regional anesthesia in the form of combined cervical plexus block is gaining popularity as a technique of choice for cervical spine surgeries, especially for urgent ones. An important advantage is that it allows continuous monitoring of patient's neurological status. The success of the block often depends on accurate placement of the local anesthetic. Landmarks for the block are therefore of great importance. In this case, we aimed to present a 74-year-old man with C4-5 odontoid fracture. We planned to perform a unilateral combined cervical plexus block for anterior cervical instrumentation and fusion (ACIF) operation because of his associated high-risk comorbid disorders...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29282548/the-qualyor-qualit%C3%A3-osseuse-lyon-orl%C3%A3-ans-study-a-new-cohort-for-non-invasive-evaluation-of-bone-quality-in-postmenopausal-osteoporosis-rationale-and-study-design
#13
Roland Chapurlat, Jean-Baptiste Pialat, Blandine Merle, Elisabeth Confavreux, Florence Duvert, Elisabeth Fontanges, Farida Khacef, Sylvie Loiseau Peres, Anne-Marie Schott, Eric Lespessailles
The diagnostic performance of densitometry is inadequate. New techniques of non-invasive evaluation of bone quality may improve fracture risk prediction. Testing the value of these techniques is the goal of the QUALYOR cohort. INTRODUCTION: The bone mineral density (BMD) of postmenopausal women who sustain osteoporotic fracture is generally above the World Health Organization definition for osteoporosis. Therefore, new approaches to improve the detection of women at high risk for fracture are warranted...
December 27, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29282539/the-global-spine-care-initiative-a-systematic-review-of-individual-and-community-based-burden-of-spinal-disorders-in-rural-populations-in-low-and-middle-income-communities
#14
REVIEW
Eric L Hurwitz, Kristi Randhawa, Paola Torres, Hainan Yu, Leslie Verville, Jan Hartvigsen, Pierre Côté, Scott Haldeman
PURPOSE: The purpose of this review was to synthesize literature on the burden of spinal disorders in rural communities to inform the Global Spine Care Initiative care pathway and model of care for their application in medically underserved areas and low- and middle-income countries. METHODS: A systematic review was conducted. Inclusion criteria included all age groups with nonspecific low back pain, neck pain, and associated disorders, nonspecific thoracic spinal pain, musculoskeletal chest pain, radiculopathy, or spinal stenosis...
December 27, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29282463/prevalence-of-work-related-musculoskeletal-disorders-among-surgeons-and-interventionalists-a-systematic-review-and-meta-analysis
#15
Sherise Epstein, Emily H Sparer, Bao N Tran, Qing Z Ruan, Jack T Dennerlein, Dhruv Singhal, Bernard T Lee
Importance: Physicians in procedural specialties are at high risk for work-related musculoskeletal disorders (MSDs). This has been called "an impending epidemic" in the context of the looming workforce shortage; however, prevalence estimates vary by study. Objectives: To estimate the prevalence of work-related MSDs among at-risk physicians and to evaluate the scope of preventive efforts. Data Sources and Study Selection: Systematic search in MEDLINE (Ovid), Embase (Elsevier), Web of Science, PubMed (National Center for Biotechnology Information), and 2 clinical trial registries, without language restriction, for studies reporting on the prevalence and prevention of work-related MSDs among at-risk physicians published until December 2016...
December 27, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29282295/common-fibrillar-spines-of-amyloid-%C3%AE-and-human-islet-amyloid-polypeptide-revealed-by-micro-electron-diffraction-and-inhibitors-developed-using-structure-based-design
#16
Pascal Krotee, Sarah L Griner, Michael R Sawaya, Duilio Cascio, Jose A Rodriguez, Dan Shi, Stephan Philipp, Kevin Murray, Lorena Saelices, Ji Lee, Paul Seidler, Charles G Glabe, Lin Jiang, Tamir Gonen, David S Eisenberg
Amyloid-β (Aβ) and human islet amyloid polypeptide (hIAPP) aggregate to form amyloid fibrils that deposit in tissues, and are associated with Alzheimer's disease (AD) and Type-II Diabetes (T2D), respectively. Individuals with T2D have an increased risk of developing AD, and conversely, AD patients have an increased risk of developing T2D. Evidence suggests that this link between AD and T2D might originate from a structural similarity between aggregates of Aβ and hIAPP. Using the cryoEM method Micro-Electron Diffraction (MicroED) we determined the atomic structures of 11-residue segments from both Aβ and hIAPP, termed Aβ 24-34 WT and hIAPP 19-29 S20G, with 64% sequence similarity...
December 27, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29281126/effects-of-gastric-bypass-surgery-on-bone-mass-and-microarchitecture-occur-early-and-particularly-impact-postmenopausal-women
#17
Anne L Schafer, Galateia J Kazakia, Eric Vittinghoff, Lygia Stewart, Stanley J Rogers, Tiffany Y Kim, Jonathan T Carter, Andrew M Posselt, Courtney Pasco, Dolores M Shoback, Dennis M Black
Roux-en-Y gastric bypass (RYGB) surgery is a highly effective treatment for obesity but negatively affects the skeleton. Studies of skeletal effects have generally examined areal BMD by DXA, but DXA may be inaccurate in the setting of marked weight loss. Further, as a result of modestly sized samples of mostly premenopausal women and very few men, effects of RYGB by sex and menopausal status are unknown. We prospectively studied the effects of RYGB on skeletal health, including axial and appendicular volumetric BMD and appendicular bone microarchitecture and estimated strength...
December 27, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29278603/interventional-spine-and-pain-procedures-in-patients-on-antiplatelet-and-anticoagulant-medications-second-edition-guidelines-from-the-american-society-of-regional-anesthesia-and-pain-medicine-the-european-society-of-regional-anaesthesia-and-pain-therapy-the
#18
Samer Narouze, Honorio T Benzon, David Provenzano, Asokumar Buvanendran, José De Andres, Timothy Deer, Richard Rauck, Marc A Huntoon
The American Society of Regional Anesthesia and Pain Medicine (ASRA) 2012 survey of meeting attendees showed that existing ASRA anticoagulation guidelines for regional anesthesia were insufficient for their needs. Those surveyed agreed that procedure-specific and patient-specific factors required separate guidelines for pain and spine procedures. In response, a guidelines committee was formed. After preliminary review of published complications reports and studies, the committee stratified interventional spine and pain procedures according to potential bleeding risk: low-, intermediate-, and high-risk procedures...
December 22, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29277590/feasibility-of-a-modified-e-pass-and-possum-system-for-postoperative-risk-assessment-in-patients-with-spinal-disease
#19
Dong Hyun Chun, Do Young Kim, Sun Kyu Choi, Dong Ah Shin, Yoon Ha, Keung Nyun Kim, Do Heum Yoon, Seong Yi
STUDY DESIGN: Retrospective case control study OBJECTIVE: This study aimed to evaluate the feasibility of using Estimation of Physiological Ability and Surgical Stress (E-PASS) and Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM) systems in patients undergoing spinal surgical procedures. SUMMARY OF BACKGROUND DATA: Degenerative spine disease has increased in incidence in aging societies, as has the number of older adult patients undergoing spinal surgery...
December 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29276420/effects-of-minerva-orthosis-on-larynx-height-in-young-healthy-volunteers
#20
Pegah Saddat Hosseini, Mohammad Taghi Karimi, Saeideh Moayedfar, Marzieh Golabbakhsh, Fatemeh Abnavi
Background: During speech, larynx is higher in the neck for high-pitched sounds and lower for low-pitched sounds. Patients with different problems in cervical and cervicothoracic spine use cervical orthosis to limit cervical motion. This study aimed to evaluate the effects of Minerva orthosis on larynx height in young, healthy volunteers. Subjects and methods: This study included 18 subjects. Acoustic measurement of frequency variability has been assessed in 3 brace conditions: (1) without brace, (2) with brace, and (3) 30 minutes after wearing the brace...
2017: Clinical Medicine Insights. Ear, Nose and Throat
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