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Otorhinolaryngology

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https://www.readbyqxmd.com/read/29141287/-observation-of-systemic-adverse-reactions-by-specific-immunotherapy-and-analysis-of-risk-factors-in-allergic-rhinitis
#1
Y Shen, S L Hong, M Zhang, X Ke
Objective: To investigate the systemic adverse effects of specific subcutaneous immunotherapy (SCIT) in patients with allergic rhinitis (AR) and explore the possible risk factors. Methods: A retrospective study was conducted on AR patients who underwent SCIT from January 2014 to January 2017 in Department of Otorhinolaryngology, the First Affiliated Hospital of Chongqing Medical University. For patients with adverse reactions, the detailed medical history during treatment was reviewed. Results: A total of 1608 injections were performed on 102 patients, there were 12 cases / 21 times systemic adverse events, including systemic urticaria, angioedema and Grade Ⅰ systemic adverse reactions...
November 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29135113/minichromosome-maintenance-mcm-protein-4-overexpression-is-a-potential-prognostic-marker-for-laryngeal-squamous-cell-carcinoma
#2
Jianfeng Han, Meng Lian, Jugao Fang, Honggang Liu, Ru Wang, Jie Zhai, Yi Fan Yang, Ling Fen, Qian Shi, Hong Zhi Ma, Juan Sun, Zhihong Ma
PURPOSE: The minichromosomal maintenance (MCM) proteins are involved in the initiation and DNA replication. The role of MCM4 remains to be elucidated. The purpose of this study was to investigate the effects of MCM4 in laryngeal squamous cell carcinoma (LSCC) cell growth and apoptosis. METHODS: LSCC cell line UMSCC 5 was used in this study. The small interfering RNA (siRNA) of MCM 4 gene was used to identify the effects of MCM4 on the proliferation and apoptosis using methylimidazole tetrazolium (MTT) assay and flow-cytometry, respectively...
September 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29131364/quality-of-life-is-significantly-impaired-in-non-allergic-rhinitis-patients
#3
Christine L Segboer, Ingrid Terreehorst, Artur Gevorgyan, Peter W Hellings, Cornelis M van Drunen, Wytske J Fokkens
BACKGROUND: In contrast to the well-known significant impairment of quality of life (QoL) in allergic rhinitis (AR), the degree of impairment in QoL in non-allergic rhinitis (NAR) remained unknown for a long time, due to a lack of a validated questionnaire to assess QoL in the NAR patient group. In this study a validation for the mini-RQLQ questionnaire in NAR patients was performed, followed by an assessment of QoL in NAR patients compared to AR and healthy controls. Secondly, use of medication and treatment satisfaction in AR and NAR was assessed...
November 13, 2017: Allergy
https://www.readbyqxmd.com/read/29121384/correlation-between-sensorineural-hearing-loss-and-chronic-otorrhea
#4
Fernanda Martinho Dobrianskyj, Ísis Rocha Gonçalves, Yumi Tamaoki, Edson Ibrahim Mitre, Fernando A Ribeiro
Many studies have attempted to correlate chronic otorrhea in children and in adults with the sensorineural hearing loss in the affected ear, with contradictory results. This loss might be the result of the likely toxicity of the bacteria involved, effects of inflammatory cytokines, or constant use of ototoxic antibiotics. All studies evaluated to date compared the affected ear with the normal contralateral ear. From the digitized archive of otologic surgery files of the Department of Otorhinolaryngology at Santa Casa de São Paulo School of Medical Sciences, the ears of patients with chronic otorrhea were evaluated visually and compared with the normal contralateral ears...
October 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29119844/symptom-relief-and-health-related-quality-of-life-in-globus-patients-a-prospective-study
#5
Pia Järvenpää, Assi Laatikainen, Risto P Roine, Harri Sintonen, Perttu Arkkila, Leena-Maija Aaltonen
Globus may be a persistent symptom impairing patients' quality of life. Diagnostics and treatment are controversial but some globus patients may benefit from reassurance and attention. We investigated how globus symptoms change during a short-term follow-up without any treatment after an examination by an ear, nose and throat (ENT) physician and further diagnostic procedures. We also surveyed whether patients with persistent globus suffer from simultaneous voice problems. The study comprised 30 consecutive globus patients referred to Helsinki University Hospital, Department of Otorhinolaryngology - Head and Neck Surgery...
November 9, 2017: Logopedics, Phoniatrics, Vocology
https://www.readbyqxmd.com/read/29118826/prevalence-of-hpv-infection-in-hypopharyngeal-and-laryngeal-squamous-cell-carcinoma-at-thailand-s-largest-tertiary-referral-center
#6
Warut Pongsapich, Nitathip Eakkasem, Sontana Siritantikorn, Paveena Pithuksurachai, Kshidej Bongsabhikul, Cheerasook Chongkolwatana
Background: Following the well-established relationship between human papillomavirus (HPV) and cervical carcinoma, the carcinogenicity of this virus has also been confirmed in subsets of head and neck carcinoma (HNCA), but mainly in the oropharynx. Other subsites of HNCA with less known association to HPV have never been studied in Thailand. Accordingly, the aim of this study was to investigate the prevalence of HPV DNA in hypopharyngeal and laryngeal squamous cell carcinoma in Thai population...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29118675/selecting-optimal-second-generation-antihistamines-for-allergic-rhinitis-and-urticaria-in-asia
#7
Marysia Tiongco Recto, Ma Teresita Gabriel, Kanokvalai Kulthanan, Pongsakorn Tantilipikorn, Derrick Chen-Wee Aw, Tak Hong Lee, Ch'ng Chin Chwen, Somasundran Mutusamy, Nguyen Trong Hao, Vo Thanh Quang, Giorgio Walter Canonica
Background: Allergic diseases are on the rise in many parts of the world, including the Asia-Pacific (APAC) region. Second-generation antihistamines are the first-line treatment option in the management of allergic rhinitis and urticaria. International guidelines describe the management of these conditions; however, clinicians perceive the additional need to tailor treatment according to patient profiles. This study serves as a consensus of experts from several countries in APAC (Hong Kong, Malaysia, the Philippines, Singapore, Thailand, Vietnam), which aims to describe the unmet needs, practical considerations, challenges, and key decision factors when determining optimal second-generation antihistamines for patients with allergic rhinitis and/or urticaria...
2017: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/29106863/clinical-variables-determining-the-success-of-adenotonsillectomy-in-children-with-down-syndrome
#8
Maíra da Rocha, Renata Caroline Mendonça Ferraz, Vitor Guo Chen, Gustavo Antonio Moreira, Reginaldo Raimundo Fujita
OBJECTIVES: To evaluate the evolution of polysomnographic parameters of children with Down syndrome and obstructive sleep apnea syndrome submitted to adenotonsillectomy and the interaction of comorbidities on therapeutic outcome. METHODS: Ninety patients with Down syndrome and habitual snoring were identified between 2005 and 2015 in a Pediatric Otorhinolaryngology Clinic. Parent's complaints were evaluated by the test of equality of two proportions. Wilcoxon test was used to examine pre- and post-operative polysomnographic differences...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29103091/proceedings-of-the-rami-section-of-otorhinolaryngology-head-and-neck-surgery-orl-hns-spring-meeting-saturday-8th-april-2017
#9
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29072006/-rule-of-clinical-application-of-auricular-acupuncture-based-on-data-mining
#10
Na Bao, Qiong Wang, Yan-Hui Sun, Jing Shi, Xiao-Feng Li, Jing Xu, Hai-Jiao Xing, Xuan-Ping Zhang, Xin Zhang, Yu-Zhu Du, Jun-Lei Li, Qing-Qing Yang, Xin-Xin Feng, Chun-Sheng Jia, Jian-Ling Wang
OBJECTIVE: To explore the rule of clinical application of auricular acupuncture therapy by data mining in order to guide clinical practice. METHODS: The data base about single auricular acupuncture therapy for different clinical diseases was established by collection, sorting, screening, recording, collation, data extraction, statistic analysis on data samples from journals, academic theses dissertations published in near 60 years. The application rules of auricular therapy including its predominant diseases, stimulus modality, therapeutic effect, and angle of needling were summarized by data mining technique...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29065268/high-level-disinfection-of-otorhinolaryngology-clinical-instruments-an-evaluation-of-the-efficacy-and-cost-effectiveness-of-instrument-storage
#11
Pratyusha Yalamanchi, Jason Yu, Laura Chandler, Natasha Mirza
Objectives Despite increasing interest in individual instrument storage, risk of bacterial cross-contamination of otorhinolaryngology clinic instruments has not been assessed. This study is the first to determine the clinical efficacy and cost-effectiveness of standard high-level disinfection and clinic instrument storage. Methods To assess for cross-contamination, surveillance cultures of otorhinolaryngology clinic instruments subject to standard high-level disinfection and storage were obtained at the start and end of the outpatient clinical workday...
October 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29045003/barbed-expansion-sphincter-pharyngoplasty-for-the-treatment-of-oropharyngeal-collapse-in-obstructive-sleep-apnoea-syndrome-a-retrospective-study-on-17-patients
#12
LETTER
L Pianta, G Bertazzoni, R Morello, P Perotti, P Nicolai
No abstract text is available yet for this article.
October 16, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29033126/vertigo-and-dizziness-in-hospital-attendance-flow-and-characteristics-of-patients
#13
Carmen Bécares Martínez, Marta M Arroyo Domingo, Aurora López Llames, Jaime Marco Algarra, María M Morales Suárez-Varela
INTRODUCTION AND OBJECTIVES: Vertigo and dizziness as symptoms are frequent in the population. They are present in a wide range of pathologies and it is usually difficult to make an accurate diagnosis. The general objective of this study is to obtain the information to evaluate vertigo and dizziness in the hospital setting. The specific objectives are: to estimate the burden of these symptoms at the hospital; to study patients' conditions and to detail the flow of these patients inside the hospital...
October 12, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29021451/otitis-media-with-anca-associated-vasculitis-a-new-concept-and-the-associated-criteria
#14
Yusuke Kobari, Tasuku Nagasawa
A previously healthy 77-year-old Japanese man presented with a 2-week history of daily fevers peaking at 38°C, chills, hearing loss, and almost 10 kg of unintentional weight loss over 2 months. Pure tone audiometry showed mixed conductive-sensorineural hearing loss: right, 63.6 dB, left, 80.0 dB. Blood tests after admission showed a high myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) level (>300 U/mL), so we suspected ANCA-related vasculitis. The Japanese Otorhinolaryngology Society has recently been advocating the concept of otitis media with ANCA-associated vasculitis (OMAAV)...
October 11, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29018494/evaluation-of-the-efficacy-and-tolerability-of-oral-ciprofloxacin-used-in-the-comprehensive-treatment-of-external-bacterial-otitis-an-observational-prospective-study
#15
Alexander Vladimirovich Gurov, Andrey Ivanovich Kriukov, Vera Yakovlevna Kunelskaya, Galina Nikolaevna Isotova, Georgiy Borisovich Shadrin, Yuliya Vladislavovna Luchsheva, Vladislav Olegovich Yakimov, Amit Garg, Shyam Prasad Akku, Namita Gupta
Introduction  Otitis Externa is common ear infection with a prevalence of 1%. Objective  The objective of this study is to evaluate the clinical and microbiological efficacy and safety profile with oral ciprofloxacin in the external bacterial otitis (EBO) management. Methods  This is a prospective observational study conducted with EBO outpatients referred to the otorhinolaryngology center in Moscow between March and August 2013. Our study included patients from two cohorts, acute external bacterial otitis (AEBO) - Group 1 - and exacerbation of chronic otitis externa (CEBO) - Group 2...
October 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28980600/-the-radicular-cyst-in-the-maxillary-sinus-encountered-in-the-clinical-otorhinolaryngological-practice
#16
A B Turovsky, I G Kolbanova, G V Kuznetsov, Yu S Kudryavtseva
This article was designed to report the clinical case of the radicular cyst localized in the maxillary sinus of the 23 year-old man that had been detected before the surgical intervention was undertaken for its treatment. In the preceding visits of the patient to other medical settings, this condition was misinterpreted as a genuine (rhinogenic) cyst. It accounted for the choice of the inadequate surgical strategy for the management of this pathology. As a result, the patient experienced two relapse episodes of the disease...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28980595/-differential-diagnostics-of-headache-associated-with-pathological-changes-in-the-nasal-cavity-and-paranasal-sinuses
#17
A I Kryukov, G Yu Tsarapkin, A S Tovmasyan, S G Arzamazov, Z O Zaoeva, A E Kishinevskii
Headache is not infrequently one of the major complaints in the patients visiting the otorhinolaryngologist's office. It was estimated to occur in 24% of the patients presenting with chronic sinusitis. The cause of headache may be pathological processes either in the nasal cavity or in the paranasal sinuses as well as a primary disorder in the nervous system. The present article is concerned with the peculiar features of rhinogenic headache and that of a different etiology. It was shown that the patients suffering from headache are in need not only of the obligatory otorhinolaryngological examination including endoscopy of the nasal cavity, X-ray study and, sometimes, specialized tests but also of neurological counseling...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28980587/-atypical-inflammation-of-the-middle-ear
#18
E V Garov, A I Kryukov, V N Zelenkova, N G Sidorina, A S Kaloshina
The objective of the present study was to characterize the patients presenting with atypical inflammation of the middle ear and consider the currently available methods for their examination. A total of 20 patients at the age from 16 to 66 years were admitted to the Department of Ear Microsurgery during the period from 2008 and 2016 for the treatment of atypical inflammation of the middle ear. Eleven of them (18 ears) were found to have tuberculous lesions (TL) of the middle ear while the remaining 9 patients (11 ears) suffered giant cell vasculitis (GCV)...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28968886/global-ethnic-and-geographic-differences-in-the-clinical-presentations-of-anti-neutrophil-cytoplasm-antibody-associated-vasculitis
#19
Fiona A Pearce, Anthea Craven, Peter A Merkel, Raashid A Luqmani, Richard A Watts
Objectives: There are few data on clinical profiles of ANCA-associated vasculitis (AAV) in different ethnic populations. The aim of this study was to examine the differences in the ANCA type and clinical features of AAV between populations using the Diagnostic and Classification Criteria in Vasculitis Study (DCVAS) dataset. Methods: The DCVAS is an international, multicentre, observational study recruiting in 133 sites. Eight ethnic categories were analysed: Northern European, Caucasian American, Southern European, Middle Eastern/Turkish, Chinese, Japanese, Indian subcontinent and other...
November 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28967586/correlation-between-voice-and-auditory-processing
#20
Janine Santos Ramos, Mariza Ribeiro Feniman, Ingrid Gielow, Kelly Cristina Alves Silverio
PURPOSE: To compare and to correlate the performance of women with behavioral dysphonia and without voice disorders in auditory processing tests and in the Voice Tone Reproduction Test (VTRT). METHODS: Forty women aged from 18 to 44 years participated and were divided in two groups: dysphonic (DG) and non-dysphonic (NDG). The participants underwent interview, hearing, otorhinolaryngology and voice assessments (voice record, VTRT through phonetography), and auditory processing assessment-using the Pitch Pattern Sequence (PPS) test and the Duration Pattern Sequence (DPS) test...
September 26, 2017: Journal of Voice: Official Journal of the Voice Foundation
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