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freeze dried plasma review

Philbert Y Van, John B Holcomb, Martin A Schreiber
PURPOSE OF REVIEW: Traumatic injuries are a major cause of mortality worldwide. Damage control resuscitation or balanced transfusion of plasma, platelets, and red blood cells for the management of exsanguinating hemorrhage after trauma has become the standard of care. We review the literature regarding the use of alternatives to achieve the desired 1 : 1:1 ratio as availability of plasma and platelets can be problematic in some environments. RECENT FINDINGS: Liquid and freeze dried plasma (FDP) are logistically easier to use and may be superior to fresh frozen plasma...
December 2017: Current Opinion in Critical Care
Justin J J Watson, Shibani Pati, Martin A Schreiber
Traumatic hemorrhage is the leading cause of preventable death after trauma. Early transfusion of plasma and balanced transfusion have been shown to optimize survival, mitigate the acute coagulopathy of trauma, and restore the endothelial glycocalyx. There are a myriad of plasma formulations available worldwide, including fresh frozen plasma, thawed plasma, liquid plasma, plasma frozen within 24 h, and lyophilized plasma (LP). Significant equipoise exists in the literature regarding the optimal plasma formulation...
November 2016: Shock
Gustavo Avila-Ortiz, P Mark Bartold, William Giannobile, Wataru Katagiri, Salvador Nares, Hector Rios, Daniel Spagnoli, Ulf Me Wikesjö
PURPOSE: The aim of this systematic review was to evaluate current and emerging regenerative approaches for implant site development in the edentulous atrophic maxilla using tissue engineering and regenerative medicine (TERM) principles and to identify priorities for future research. MATERIALS AND METHODS: Two independent examiners conducted a comprehensive search using specific keywords to identify original clinical studies using TERM for implant site development in the edentulous atrophic maxilla including indications for alveolar ridge preservation, horizontal alveolar augmentation, maxillary sinus augmentation, and augmentation of severe vertical or combined defects...
2016: International Journal of Oral & Maxillofacial Implants
Cristian Del Bo', Daniela Martini, Marisa Porrini, Dorothy Klimis-Zacas, Patrizia Riso
Berries are an excellent source of bioactive compounds such as vitamins, minerals but above all polyphenols with anthocyanins as the most representative compounds. Several in vitro and in vivo studies documented the beneficial effects of berries and their bioactives in the modulation of numerous cell functions related to oxidative stress and/or antioxidant protection. The following review summarizes published results about the role of berries (either fresh, juice, freeze-dried or dehydrated) on total plasma and serum antioxidant status and on the modulation of biomarkers of oxidative stress in acute and chronic human intervention trials...
September 2015: Food & Function
Alice Roffi, Giuseppe Filardo, Elizaveta Kon, Maurilio Marcacci
BACKGROUND: Several bone implants are applied in clinical practice, but none meets the requirements of an ideal implant. Platelet-rich plasma (PRP) is an easy and inexpensive way to obtain growth factors in physiologic proportions that might favour the regenerative process. The aim of this review is to analyse clinical studies in order to investigate the role of PRP in favouring bone integration of graft, graft substitutes, or implants, and to identify the materials for which the additional use of PRP might be associated with superior osseo- and soft tissues integration...
2013: BMC Musculoskeletal Disorders
Umashankar Pal, Niraj Mishra
There has been considerable clinical interest in combining the grafts, particularly bone allografts for support for dental implants, soft-tissue support, periodontal maintenance, and ovate pontic formation. The use of demineralized, freeze-dried bone allograft (DFDBA) offers certain advantages over other graft materials and can avoid the need for a second-site surgery for autogenous donor bone. The advantages of DFDBA include handling properties, osteoinductivity, membrane tenting, and less susceptibility to migration after placement...
October 2012: Contemporary Clinical Dentistry
Amy C Brown
This review investigated the relationship of noni juice, or its extract (fruit, leaves or root), to anticancer and/or immunostimulant properties. A Medline search was conducted using the key search words 'Morinda citrifolia' and 'Morinda citrifolia and cancer' (1964 to October, 2011) along with cross-referencing. Botanical and chemical indexes were not included. A total of 304 and 29 (10%) articles, respectively, were found under these key terms. Of the 19 studies actually related to cancer, seven publications were in vitro cancer studies, nine were in vivo animal cancer studies, and three were in vivo human cancer studies...
October 2012: Phytotherapy Research: PTR
Anne Godier, Charles-Marc Samama, Sophie Susen
PURPOSE OF REVIEW: The scope of this review is to describe what is known about blood product ratios and their effects on acute trauma coagulopathy. Assessing how ratios matter to trauma patients is important to improve massive transfusion strategies. RECENT FINDINGS: A growing body of evidence supports that high ratios of fresh frozen plasma and platelets to red blood cells improve survival of the massively bleeding traumatized patient. Acting quickly is also critical...
April 2012: Current Opinion in Anaesthesiology
Silvia Bertagnolio, Neil T Parkin, Michael Jordan, James Brooks, J Gerardo García-Lerma
HIV-1 drug resistance genotyping is an essential component of the World Health Organization global HIV Drug Resistance (HIVDR) prevention and assessment strategy. Plasma is considered to be the most appropriate specimen type for HIV-1 drug resistance genotyping. However, use of plasma may not be feasible in rural, remote areas in resource-limited settings since its preparation and storage requires personnel and laboratory infrastructure that is often lacking. An alternative specimen type for HIVDR genotyping is dried blood spots (DBS)...
October 2010: AIDS Reviews
Nikolaos Markou, Eudoxie Pepelassi, Sotirios Kotsovilis, Ioannis Vrotsos, Helen Vavouraki, Harry Charalabos Stamatakis
BACKGROUND: On the basis of systematic reviews and randomized controlled trials, the authors provide reports of two cases in which platelet-rich plasma (PRP) combined with demineralized freeze-dried bone allograft (DFDBA) was used to treat periodontal endosseous defects. CASE DESCRIPTION: Clinicians treated two circumferential endosseous defects with a probing pocket depth of 5 and 8 millimeters, respectively (case 1), and a combined 1-2-3-wall endosseous defect with a probing pocket depth of 6 mm (case 2) by using the combination of PRP and DFDBA...
August 2010: Journal of the American Dental Association
Michael S Lee, Valerie Tallerico
Distraction arthrodesis of the subtalar joint is often used for the correction of neglected calcaneal fractures. Although different techniques have been advocated, there remains some debate as to the optimal type of bone graft for this purpose. This study retrospectively reviewed one surgeon's results for distraction arthrodesis of the talocalcaneal joint for 15 consecutive feet in 15 patients using 12 frozen femoral head and 3 freeze-dried iliac crest allografts. Indications for distraction arthrodesis in this series included neglected calcaneal fracture (n = 10), failed open reduction with internal fixation (n = 3), malunion after ankle fusion (n = 1), and subtalar joint arthritis with deformity (n = 1)...
July 2010: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Viviana V Johnson, Sean A Swiatkowski
PURPOSE OF REVIEW: Reduction in combat zone morbidity and mortality requires rapid delivery of safe blood products as an integral element of advanced trauma surgical care. This review of the current literature presents scientific aspects of supplying blood for rapid delivery to enhance survival and patient outcome in the combat zone. RECENT FINDINGS: Most deaths due to hemorrhage can be averted by transfusion during the first hour from injury; therefore, maintaining a dependable inventory of blood products in combat support hospitals is essential...
November 2007: Current Opinion in Hematology
Paolo De Paoli
Millions of biological samples, including cells of human, animal or bacterial origin, viruses, serum/plasma or DNA/RNA, are stored every year throughout the world for diagnostics and research. The purpose of this review is to summarize the resources necessary to set up a bio-banking facility, the challenges and pitfalls of sample collection, and the most important techniques for separation and storage of samples. Biological samples can be stored for up to 30 years, but specific protocols are required to reduce the damage induced by preservation techniques...
November 2005: FEMS Microbiology Reviews
K S Subramanian
In any well-defined study, a sample preservation and storage scheme compatible with the information or analyte sought should be incorporated. This article emphasizes the need for preservation and storage of biological fluids collected for trace element determination; cites the major factors, such as container material, container pretreatment, storage time, storage temperature, and contamination of the laboratory environment affecting preservation; presents a historical account of the available literature studies on the preservation and storage of trace metals in whole blood, plasma, serum, and urine; and makes recommendations on the most effective storage and preservation methods...
August 1995: Biological Trace Element Research
J Vermylen, K Peerlinck
A recent increased incidence of hepatitis A in the hemophilia populations of Italy, Germany, Belgium and Ireland was studied. The first well-documented outbreak occurred in Italy, where 51 patients with severe hemophilia contracted hepatitis A between the years 1989 and 1992. A case-control study by Mannucci et al. of the first 29 consecutive cases of hemophilia patients with jaundice led to the conclusion that hepatitis A was transmitted to Italian hemophilia patients by solvent-detergent-treated, ion-exchange-purified concentrate...
1994: Vox Sanguinis
R I Greaves
No abstract text is available yet for this article.
July 1968: Cryobiology
M V Nermut
Over the past decade new methods have been developed to visualize both the external and the protoplasmic surfaces of cultured cells in the electron microscope. In this review the emphasis is on cell monolayers, though some of the techniques are also applicable to cells in suspension. There is no universal method which would satisfy all our requirements i.e. the preservation of native structure and antigenicity and the visualization of the whole cell surface at high resolution. While surface replicas of freeze-dried or critical point-dried cells are eminently suited for high resolution studies including gold immunolabelling, scanning electron microscopy provides a view of the whole cell and a large sample for 'statistical' evaluation...
1989: Electron Microscopy Reviews
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