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https://www.readbyqxmd.com/read/28736468/multi-atlas-spleen-segmentation-on-ct-using-adaptive-context-learning
#1
Jiaqi Liu, Yuankai Huo, Zhoubing Xu, Albert Assad, Richard G Abramson, Bennett A Landman
Automatic spleen segmentation on CT is challenging due to the complexity of abdominal structures. Multi-atlas segmentation (MAS) has shown to be a promising approach to conduct spleen segmentation. To deal with the substantial registration errors between the heterogeneous abdominal CT images, the context learning method for performance level estimation (CLSIMPLE) method was previously proposed. The context learning method generates a probability map for a target image using a Gaussian mixture model (GMM) as the prior in a Bayesian framework...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28727749/student-perception-of-group-dynamics-predicts-individual-performance-comfort-and-equity-matter
#2
Elli J Theobald, Sarah L Eddy, Daniel Z Grunspan, Benjamin L Wiggins, Alison J Crowe
Active learning in college classes and participation in the workforce frequently hinge on small group work. However, group dynamics vary, ranging from equitable collaboration to dysfunctional groups dominated by one individual. To explore how group dynamics impact student learning, we asked students in a large-enrollment university biology class to self-report their experience during in-class group work. Specifically, we asked students whether there was a friend in their group, whether they were comfortable in their group, and whether someone dominated their group...
2017: PloS One
https://www.readbyqxmd.com/read/28724149/using-reflections-to-evaluate-the-stfm-behavioral-science-family-systems-educator-fellowship
#3
Deborah A Taylor, Victoria Gorski, Sandra K Burge
BACKGROUND AND OBJECTIVES: A group of family medicine educators identified a need and developed a 1-year fellowship for early career behavioral science educators. This occurred in response to a reduction in previous opportunities and resources. The program was designed to shape and mentor new behavioral science faculty teaching in family medicine departments and programs. Quantitative data analysis from pre- and post-fellowship survey data from years 1-4 confirmed fellowship objectives were met...
July 2017: Family Medicine
https://www.readbyqxmd.com/read/28723659/data-driven-analysis-of-immune-infiltrate-in-a-large-cohort-of-breast-cancer-and-its-association-with-disease-progression-er-activity-and-genomic-complexity
#4
Ruth Dannenfelser, Marianne Nome, Andliena Tahiri, Josie Ursini-Siegel, Hans Kristian Moen Vollan, Vilde D Haakensen, Åslaug Helland, Bjørn Naume, Carlos Caldas, Anne-Lise Børresen-Dale, Vessela N Kristensen, Olga G Troyanskaya
The tumor microenvironment is now widely recognized for its role in tumor progression, treatment response, and clinical outcome. The intratumoral immunological landscape, in particular, has been shown to exert both pro-tumorigenic and anti-tumorigenic effects. Identifying immunologically active or silent tumors may be an important indication for administration of therapy, and detecting early infiltration patterns may uncover factors that contribute to early risk. Thus far, direct detailed studies of the cell composition of tumor infiltration have been limited; with some studies giving approximate quantifications using immunohistochemistry and other small studies obtaining detailed measurements by isolating cells from excised tumors and sorting them using flow cytometry...
July 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28720423/undergraduate-clinical-teaching-in-orthopedic-surgery-a-randomized-control-trial-comparing-the-effect-of-case-based-teaching-and-bedside-teaching-on-musculoskeletal-osce-performance
#5
Martin Kelly, Iain Feeley, Fiona Boland, John M O'Byrne
INTRODUCTION: Musculoskeletal (MSK) complaints are the second most common reason for a hospital outpatient appointment in the US, and account for 19.5% of general practice consultations. Previous studies have shown that passive teaching in medical school does not imbue students with an adequate degree of confidence in MSK evaluation. The aim of this study was to conduct a randomized control trial to compare the effect of the gold standard small group tutorial of bedside teaching against case-based teaching (CBT) in relation to orthopedic surgery in medical students...
July 15, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28713801/an-evaluation-of-a-train-the-trainer-workshop-for-social-service-workers-to-develop-community-based-family-interventions
#6
Agnes Y Lai, Sunita M Stewart, Moses W Mui, Alice Wan, Carol Yew, Tai Hing Lam, Sophia S Chan
INTRODUCTION: Evaluation studies on train-the-trainer workshops (TTTs) to develop family well-being interventions are limited in the literature. The Logic Model offers a framework to place some important concepts and tools of intervention science in the hands of frontline service providers. This paper reports on the evaluation of a TTT for a large community-based program to enhance family well-being in Hong Kong. METHODS: The 2-day TTT introduced positive psychology themes (relevant to the programs that the trainees would deliver) and the Logic Model (which provides a framework to guide intervention development and evaluation) for social service workers to guide their community-based family interventions...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28712674/the-ebbinghaus-illusion-in-the-gray-bamboo-shark-chiloscyllium-griseum-in-comparison-to-the-teleost-damselfish-chromis-chromis
#7
Theodora Fuss, Vera Schluessel
This is the first study to comparatively assess the perception of the Ebbinghaus-Titchener circles and variations of the Delboeuf illusion in four juvenile bamboo sharks (Chiloscyllium griseum) and five damselfish (Chromis chromis) using identical training paradigms. We aimed to investigate whether these two species show similarities in the perceptual integration of local elements into the global context. The Ebbinghaus-Titchener circles consist of two equally sized central test circles surrounded by smaller or larger circles of different size, number and/or distance...
May 29, 2017: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/28709045/enhancing-performance-expectancies-through-visual-illusions-facilitates-motor-learning-in-children
#8
Moslem Bahmani, Gabriele Wulf, Farhad Ghadiri, Saeed Karimi, Rebecca Lewthwaite
In a recent study by Chauvel, Wulf, and Maquestiaux (2015), golf putting performance was found to be affected by the Ebbinghaus illusion. Specifically, adult participants demonstrated more effective learning when they practiced with a hole that was surrounded by small circles, making it look larger, than when the hole was surrounded by large circles, making it look smaller. The present study examined whether this learning advantage would generalize to children who are assumed to be less sensitive to the visual illusion...
July 11, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28707277/open-label-allopregnanolone-treatment-of-men-with-fragile-x-associated-tremor-ataxia-syndrome
#9
J Y Wang, A M Trivedi, N R Carrillo, J Yang, A Schneider, C Giulivi, P Adams, F Tassone, K Kim, S M Rivera, N Lubarr, C-Y Wu, R W Irwin, R D Brinton, J M Olichney, M A Rogawski, R J Hagerman
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder affecting approximately 45% of male and 16% of female carriers of the FMR1 premutation over the age of 50 years. Currently, no effective treatment is available. We performed an open-label intervention study to assess whether allopregnanolone, a neurosteroid promoting regeneration and repair, can improve clinical symptoms, brain activity, and magnetic resonance imaging (MRI) measurements in patients with FXTAS. Six patients underwent weekly intravenous infusions of allopregnanolone (2-6 mg over 30 min) for 12 weeks...
July 13, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28705246/effects-of-additional-team-based-learning-on-students-clinical-reasoning-skills-a-pilot-study
#10
Meike Jost, Peter Brüstle, Marianne Giesler, Michel Rijntjes, Jochen Brich
BACKGROUND: In the field of Neurology good clinical reasoning skills are essential for successful diagnosing and treatment. Team-based learning (TBL), an active learning and small group instructional strategy, is a promising method for fostering these skills. The aim of this pilot study was to examine the effects of a supplementary TBL-class on students' clinical decision-making skills. METHODS: Fourth- and fifth-year medical students participated in this pilot study (static-group comparison design)...
July 14, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28701497/teaching-neurology-to-medical-students-with-a-simplified-version-of-team-based-learning
#11
Jochen Brich, Meike Jost, Peter Brüstle, Marianne Giesler, Michel Rijntjes
OBJECTIVE: To compare the effect of a simplified version of team-based learning (sTBL), an active learning/small group instructional strategy, with that of the traditionally used small group interactive seminars on the acquisition of knowledge and clinical reasoning (CR) skills. METHODS: Third- and fourth-year medical students (n = 122) were randomly distributed into 2 groups. A crossover design was used in which 2 neurologic topics were taught by sTBL and 2 by small group interactive seminars...
July 12, 2017: Neurology
https://www.readbyqxmd.com/read/28699210/driving-in-search-of-analyses
#12
Bruce Simons-Morton
Although transportation safety has greatly improved over the past 2 decades, motor vehicle crash injuries remain a leading cause of morbidity and mortality, particularly among young drivers. Driver errors and behaviors such as speeding and distraction contribute disproportionately to crashes among inexperienced novices, who develop safe driving judgment only with substantial driving experience, commonly described as the "young driver problem." Research on young drivers has applied a range of research methods, including analyses of national archival data (mainly from police reports), crash analyses, observation of driver behavior, surveys of driver behavior and dispositions, and experimental research on driver behavior and vehicle crash worthiness...
July 11, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28692635/resisting-recist-uniformity-versus-clinical-validity
#13
Michelle K Wilson, Michael L Friedlander, Stephanie Lheureux, William Small, Andrés Poveda, Eric Pujade-Lauraine, Katherine Karakasis, Monica Bacon, Valerie Bowering, Tanya Chawla, Amit M Oza
OBJECTIVES: The Response Evaluation Criteria in Solid Tumors (RECIST) International Working Group developed criteria for tumor response and progression to standardize radiological assessment in patients receiving chemotherapy in phase 2 trials. However, it is unclear whether the defined percentage change in tumor size and volume reflects true clinical benefit for the patient. The RECIST criteria were designed to improve objectivity in trials, but not to replace clinical decision making...
July 7, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28691734/regulating-approaches-to-learning-testing-learning-strategy-convergences-across-a-year-at-university
#14
Luke K Fryer, Jan D Vermunt
BACKGROUND: Contemporary models of student learning within higher education are often inclusive of processing and regulation strategies. Considerable research has examined their use over time and their (person-centred) convergence. The longitudinal stability/variability of learning strategy use, however, is poorly understood, but essential to supporting student learning across university experiences. AIMS: Develop and test a person-centred longitudinal model of learning strategies across the first-year university experience...
July 10, 2017: British Journal of Educational Psychology
https://www.readbyqxmd.com/read/28691073/group-problem-solving-in-class-improves-undergraduate-learning
#15
Brent R Stockwell, Melissa S Stockwell, Elise Jiang
Developing methods for improving student learning is a long-standing goal in undergraduate science education. However, the extent to which students working on problems in small groups versus individually results in improved learning among undergraduate science students has not been evaluated in a randomized controlled trial. We have performed such a trial with 80 students in an undergraduate biochemistry class, in which students were randomized to either learning in groups or learning individually. All students participated in the same class, which consisted of a lecture with periodic breaks for students to solve problems using an audience response system...
June 28, 2017: ACS Central Science
https://www.readbyqxmd.com/read/28690434/don-t-believe-the-gripe-increasing-course-structure-in-a-large-non-majors-neuroscience-course
#16
Anastasia Nagel, Andrea Nicholas
Active teaching is increasingly accepted as a better option for higher education STEM courses than traditional lecture-based instruction. However, concerns remain regarding student preferences and the impact of increased course structure on teaching evaluations. Undergraduates in a non-majors neuropharmacology course were enrolled in an enriched blended course format, providing online case-based learning opportunities in a large lecture hall setting. Students working in small assigned groups solved weekly case studies developed to teach basic neuropharmacology concepts...
2017: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/28685632/twelve-tips-for-delivering-successful-interprofessional-case-conferences
#17
Bridget C O'Brien, Shalini R Patel, Meg Pearson, Abigail P Eastburn, Gillian E Earnest, Anna Strewler, Krista Gager, Jennifer K Manuel, Maya Dulay, Melissa R Bachhuber, Rebecca Shunk
Interprofessional case conferences (ICCs) offer an interactive, practical way to engage members of two or more health professions in discussions that involve learning and working together to improve patient care. Well-orchestrated ICCs provide opportunities to integrate interprofessional (IP) education into routine clinical practice. The authors provide 12 tips to support the conceptualization, planning, implementation, facilitation, evaluation, and sustainability of ICCs. They draw from extensive experience as IP educators and facilitators of ICCs and from literature on IP education, case-based learning, small-group facilitation, peer-assisted learning, and learner engagement - all of which offer insights into ICCs but have not been integrated and applied to this context...
July 7, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28684916/simulated-interprofessional-learning-activities-for-rural-health-care-services-perceptions-of-health-care-students
#18
Selina Taylor, Yaqoot Fatima, Navaratnam Lakshman, Helen Roberts
BACKGROUND: The literature on interprofessional learning (IPL) has limited empirical evidence on the impact of simulated IPL sessions in promoting collaborative health care services in rural settings. This study aims to explore health care students' perception of the relevance of simulated IPL for rural health care services. METHODS: Three focus group interviews were held with pre-registration medical, pharmacy, and allied health students (n=22). Students worked together to manage complex simulation scenarios in small interprofessional teams...
2017: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/28682507/taking-on-the-doctor-role-in-whole-task-simulation
#19
Maggie Bartlett, Simon P Gay, Ruth Kinston, Robert McKinley
BACKGROUND: Untimed simulated primary care consultations focusing on safe and effective clinical outcomes were first introduced into undergraduate medical education in Otago, New Zealand, in 2004. We extended this concept and included a secondary care version for final-year students. We offer students opportunities to manage entire consultations, which include making and implementing clinical decisions with simulated patients (SPs). Formative feedback is given by SPs on the achievement of pre-determined outcomes and by faculty members on clinical decision making, medical record keeping and case presentation...
July 6, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28680403/scopolamine-induces-deficits-in-spontaneous-object-location-recognition-and-fear-learning-in-marmoset-monkeys
#20
Jonathan L Melamed, Fernando M de Jesus, Rafael S Maior, Marilia Barros
The non-selective muscarinic receptor antagonist scopolamine (SCP) induces memory deficits in both animals and humans. However, few studies have assessed the effects of amnesic agents on memory functions of marmosets - a small-bodied neotropical primate that is becoming increasingly used as a translational model for several neuropathologies. Here we assessed the effects of an acute SCP administration (0.03 mg/kg, sc) on the behavior of adult marmoset monkeys in two tasks. In the spontaneous object-location (SOL) recognition task, two identical neutral stimuli were explored on the sample trial, after which preferential exploration of the displaced versus the stationary object was analyzed on the test trial...
2017: Frontiers in Pharmacology
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