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https://www.readbyqxmd.com/read/27921413/short-time-efficiency-of-rhinophototherapy-in-management-of-patients-with-allergic-rhinitis-resistant-to-medical-therapy
#1
Soheila Alyasin, Seyed Hesamedin Nabavizadeh, Hamidreza Houshmand, Hossein Esmaeilzadeh, Sina Jelodar, Reza Amin
Allergic rhinitis is one of the most common health problems with a major effect on the quality of life. We intended to treat Allergic Rhinitis (AR) in patients who are either unresponsive to antihistamines or their job requires optimal alertness that may be disturbed by antihistamine's side effects and those who do not comply with the regular use. We tried short term phototherapy and evaluated its effect on AR. As phototherapy is effective in the treatment of atopic dermatitis (AD) and the same allergens can produce both AD and AR, phototherapy is proposed as a new tool in the AR treatment...
August 2016: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/27880031/increased-levels-of-plasma-soluble-human-leukocyte-antigen-g-in-persistent-wheezy-infants
#2
Fulya Tahan, Hatice Eke Gungor, Himmet Haluk Akar, Berkay Saraymen
BACKGROUND: Human leukocyte antigen (HLA)-G is a non-classical major histocompatibility complex (MHC) class I antigen characterized by limited polymorphism in its coding region, unique tissue expression pattern in physiologic conditions and immunomodulatory properties. Recently, many studies suggest that the levels of sHLA-G were higher in atopic asthma and allergic rhinitis (AR). However, this remains to be uncertain in wheezy infants. In the present study, it was aimed to determine sHLA-G levels in wheezy infants...
November 23, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27863816/incidence-of-allergic-rhinitis-in-a-cohort-of-young-adults-from-13-15-years-old-to-23-25-years-old-in-castellon-spain
#3
A Arnedo-Pena, Mª A Romeu-Gracia, J B Bellido-Blasco, N Meseguer-Ferrer, E Silvestre-Silvestre, F Conde, S Fernández-González, Mª A Dubon, M Ortuño-Forcada, J Fabregat-Puerto, C Fenollosa-Amposta, L Segura-Navas, Mª R Pac-Sa, L Museros-Recatala, A Vizcaino, R Tosca-Segura
BACKGROUND: The objective of this study was to estimate the incidence of Allergic Rhinitis (AR) in young adults and its risk or protective factors. METHODS: A population-based prospective cohort study was carried out in 2012. The cohort participated in the International Study of Asthma and Allergy in Childhood in Castellon in 1994 and 2002. A telephone survey was conducted using the same questionnaires. A new case of AR was defined as the participants free of the disease in 2002, who self-reported suffering from AR or taking medications for AR in the period 2002-2012...
November 15, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27847316/allergies-a-t-cells-perspective-in-the-era-beyond-the-th1-th2-paradigm
#4
REVIEW
Moritz Berker, Larissa Johanna Frank, Anja Lidwina Geßner, Niklas Grassl, Anne Verena Holtermann, Stefanie Höppner, Christian Kraef, Martin Dominik Leclaire, Pia Maier, David Alexander Christian Messerer, Lino Möhrmann, Jan Philipp Nieke, Diana Schoch, Dominik Soll, Christina Marianne Paulina Woopen
Allergic diseases have emerged as a major health care burden, especially in the western hemisphere. They are defined by overshooting reactions of an aberrant immune system to harmless exogenous stimuli. The TH1/TH2 paradigm assumes that a dominance of TH2 cell activation and an inadequate TH1 cell response are responsible for the development of allergies. However, the characterization of additional T helper cell subpopulations such as TH9, TH17, TH22, THGM-CSF and their interplay with regulatory T cells suggest further layers of complexity...
November 12, 2016: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/27791954/ocular-beh%C3%A3-et-s-disease-is-less-complicated-with-allergic-disorders-a-nationwide-survey-in-japan
#5
Yukihiro Horie, Nobuyoshi Kitaichi, Kuniaki Hijioka, Koh-Hei Sonoda, Yoshitsugu Saishin, Takeshi Kezuka, Hiroshi Goto, Masaru Takeuchi, Satoshi Nakamura, Takashi Kimoto, Machiko Shimakawa, Mihori Kita, Sunao Sugita, Manabu Mochizuki, Junko Hori, Mitsuhiro Iwata, Jun Shoji, Masahide Fukuda, Toshikatsu Kaburaki, Jiro Numaga, Hidetoshi Kawashima, Astuki Fukushima, Takeshi Joko, Nanae Takai, Yoko Ozawa, Akira Meguro, Nobuhisa Mizuki, Kenichi Namba, Susumu Ishida, Shigeaki Ohno
OBJECTIVES: Behçet's disease (BD) is a systemic inflammatory disorder polarised to the Th1 and Th17 immune systems. Allergic diseases are polarised to the Th2 immune system. The aim of the present study is to investigate the prevalence of allergic diseases in patients who have BD. METHODS: The study involved a large-scale interview survey of Japanese patients with BD at 21 institutes of ophthalmology; 353 patients (255 males and 98 females) were recruited for this study...
September 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27667736/impaired-virus-replication-and-decreased-innate-immune-responses-to-viral-infections-in-nasal-epithelial-cells-from-patients-with-allergic-rhinitis
#6
A Głobińska, M Pawełczyk, A Piechota-Polańczyk, A Olszewska-Ziąber, S Moskwa, A Mikołajczyk, A Jabłońska, P Zakrzewski, M Brauncajs, M Jarzębska, S Taka, N G Papadopoulos, M L Kowalski
PURPOSE: The aim of the study was to assess the immune response to parainfluenza virus type 3 (PIV3), rhinovirus 1B (RV1B) and intracellular Toll-like receptors (TLR) agonists in nasal epithelial cells (NECs) from patients with allergic rhinitis and healthy controls. METHODS: NECs were obtained from 8 patients with allergic rhinitis (AR) and 11 non-atopic healthy controls (HC) by nasal scraping, grown to confluence and exposed to PIV3, RV1B infection or TLR3 and TLR7/8 agonists...
September 26, 2016: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/27578221/comparison-of-the-basophil-activation-test-versus-the-nasal-provocation-test-in-establishing-eligibility-for-specific-immunotherapy
#7
Małgorzata Leśniak, Wojciech Dyga, Barbara Rusinek, Marcel Mazur, Ewa Czarnobilska
INTRODUCTION    Allergic rhinitis (AR) is the most common atopic disease. Specific immunotherapy (SIT) is the only effective treatment method for AR. In uncertain diagnostic cases, before establishing eligibility for SIT, nasal provocation tests (NPTs) should be performed. However, there are numerous contraindications to performing NPTs, and there is ongoing search for an alternative in vitro method. OBJECTIVES    The aim of the study was to determine whether a specific in vitro provocation, that is, the basophil activation test (BAT), may replace a specific in vivo provocation, that is, the NPT, in establishing patient's eligibility for SIT...
August 25, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27430981/tolerance-and-growth-in-children-with-cow-s-milk-allergy-fed-a-thickened-extensively-hydrolyzed-casein-based-formula
#8
Christophe Dupont, Elena Bradatan, Pascale Soulaines, Rita Nocerino, Roberto Berni-Canani
BACKGROUND: In case of cow's milk allergy (CMA), pediatric guidelines recommend for children the use of extensively hydrolyzed formulas (eHFs) as elimination diet. According to the American Academy of Pediatrics, the hypoallergenicity of each specific eHF should be tested in subjects with CMA. METHODS: A prospective, multicenter trial was performed to assess the tolerance/hypoallergenicity of a thickened casein-based eHF (eHCF, Allernova AR®, United Pharmaceuticals, France) in infants aged <12 months with CMA proven by a double-blind placebo-controlled food challenge...
July 18, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27429944/utility-of-the-atopy-patch-test-in-the-diagnosis-of-allergic-rhinitis
#9
REVIEW
Nicola Fuiano, Cristoforo Incorvaia
INTRODUCTION: The diagnostic work-up of allergic rhinitis (AR) is first and foremost based on the combination of clinical history data and results of skin prick tests (SPT). Other tests, including specific IgE measurement, nasal challenge, and, as a third option, component resolved diagnosis or basophil activation test, may be useful when the diagnosis is difficult because of polysensitization or when negative results of SPT are observed despite a suggestive history for allergy. The atopy patch test (APT) that assesses the type 4 delayed hypersensitivity allergy is currently not sufficiently used...
May 2016: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27428241/general-anesthesia-exposure-in-early-life-reduces-the-risk-of-allergic-diseases-a-nationwide-population-based-cohort-study
#10
Ho-Chang Kuo, Ya-Ling Yang, Shu-Chen Ho, Mindy Ming-Huey Guo, Jyun-Hong Jiang, Ying-Hsien Huang
General anesthesia (GA) has been used for second line treatment strategy for status asthmaticus in pediatric patients. The association between GA in children and risk of followed-up allergic diseases is unclear. This study aims to assess the risk of allergic diseases after GA in children.We did a nationwide retrospective cohort study by analyzing data from the National Health Insurance Research Database (NHIRD) in Taiwan. The subsequent risks for allergic diseases, including asthma (ICD-9: 493.X), allergic rhinitis (AR; ICD-9 CM code 477...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27413648/association-between-pollen-risk-indexes-air-pollutants-and-allergic-diseases-in-korea
#11
Hoseob Kim, Yoonhyung Park, Kwanjun Park, Byoungin Yoo
OBJECTIVES: This study, different from the past researches, has been conducted in all age groups to understand the association between air pollutants, pollen risk indexes, and outpatients with allergic rhinitis (AR), asthma, and atopic dermatitis (AD). METHODS: Data on air pollutants, pollen risk indexes, and outpatients with each disease were collected from 2003 through 2011 to verify the association between them. All data are time-series materials that have been observed by time (day) and region, and are in a nonlinear shape...
June 2016: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/27405740/does-adenoid-hypertrophy-affect-disease-severity-in-children-with-allergic-rhinitis
#12
Mahmut Dogru, Muhammed Fatih Evcimik, Omer Faruk Calim
Our study aims to evaluate the presence of adenoid hypertrophy (AH) in children with allergic rhinitis (AR) and the association of AH disease severity and clinical laboratory finding from retrospective, cross-sectional, and nonrandomized trial. The study included 566 children being treated and followed up for allergic rhinitis. Skin prick test for the same allergens was performed for all patients. Adenoid tissue was analyzed by an ENT specialist and the diagnosis was confirmed based on the patient history, endoscopic physical examination and radiology...
July 12, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27401310/the-association-between-hypovitaminosis-d-and-pediatric-allergic-diseases-a-korean-nationwide-population-based-study
#13
Hea-Kyoung Yang, Jaehee Choi, Woo Kyung Kim, So-Yeon Lee, Yong Mean Park, Man Yong Han, Hye-Young Kim, Myung-Il Hahm, Yoomi Chae, Kee-Jae Lee, Ho-Jang Kwon, Kangmo Ahn, Jihyun Kim
BACKGROUND: There is still considerable disagreement regarding the role of vitamin D in the development or exacerbation of allergic diseases. OBJECTIVE: To investigate the association between serum vitamin D levels and recent symptoms of allergic diseases in elementary schoolchildren. METHODS: A nationwide cross-sectional survey was conducted in children ages 6-7 years from 45 randomly selected elementary schools. The presence of atopic dermatitis (AD) or asthma was defined as medical treatment of children for AD or asthma within 12 months of the survey...
July 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27362662/the-prevalence-of-allergic-rhinitis-and-atopic-markers-in-obstructive-sleep-apnea
#14
Ghadah Gadi, Siraj Wali, Emad Koshak, Mohammad Albar, Abdulkareem Fida, Muntasir Abdelaziz, Khaled Alnoury, Nabil Alama
Allergic rhinitis (AR) related inflammation might worsen the severity of obstructive sleep apnea (OSA), however, the relationship between the two disorders remains controversial. Our aim was to determine the prevalence of AR and atopic markers in OSA. This cross-sectional study recruited participants with sleep-related complaints referred to a sleep center from February 2013 to June 2014. The diagnosis of OSA was based on the Berlin questionnaire (BQ) followed by confirmatory polysomnography (PSG). The diagnosis of AR was made via focused history and clinical examination and was confirmed by measuring atopic markers...
June 27, 2016: Journal of Epidemiology and Global Health
https://www.readbyqxmd.com/read/27279886/the-relationships-among-birth-season-sunlight-exposure-during-infancy-and-allergic-disease
#15
Jung Min Hwang, Se Hyun Oh, Mee Yong Shin
PURPOSE: The recent increase in the prevalence of allergic diseases is hypothetically attributed to immune dysregulation in turn caused by a reduction in exposure to sunlight. We explored relationships between birth season, sunlight exposure, exercise duration, and an allergic disease. METHODS: We performed a questionnaire-based survey on allergic diseases among elementary school students. Birth time was categorized according to the season (summer and winter). RESULTS: The prevalence of atopic dermatitis (AD) "symptoms ever" was higher in the children born in winter than in those born in summer (adjusted odds ratio [aOR], 1...
May 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27216352/attention-deficit-hyperactivity-disorder-related-symptoms-improved-with-allergic-rhinitis-treatment-in-children
#16
Ming-Tao Yang, Chia-Chun Chen, Wang-Tso Lee, Jao-Shwann Liang, Wen-Mei Fu, Yao-Hsu Yang
BACKGROUND: Increased prevalence of attention-deficit/hyperactivity disorder (ADHD) in children with allergic rhinitis (AR) has been reported. Our previous study showed that children with untreated AR had higher ADHD scores than did the controls. OBJECTIVE: This prospective follow-up study aimed to investigate whether elevated ADHD scores in children with AR could be decreased by AR treatment. METHODS: Sixty-eight children with AR (age range, 6-14 years) and who were drug naive were enrolled and evaluated by AR symptom score, ADHD symptom scores, and computerized continuous performance test, before and after AR therapy, which included nonpharmacologic intervention, oral antihistamines, and topical steroids...
May 2016: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/27184199/a-rhinitis-phenotype-associated-with-increased-development-of-bronchial-hyperresponsiveness-and-asthma-in-children
#17
Eun Lee, Si Hyeon Lee, Ji-Won Kwon, Yeongho Kim, Hyun-Ju Cho, Song-I Yang, Young-Ho Jung, Hyung Young Kim, Ju-Hee Seo, Byoung-Ju Kim, Hyo Bin Kim, So Yeon Lee, Ho-Jang Kwon, Soo-Jong Hong
BACKGROUND: Allergic rhinitis (AR) has a wide range of clinical features and may be accompanied by comorbid allergic diseases. OBJECTIVE: To identify rhinitis phenotypes in school aged children and to predict the prognosis for developing bronchial hyperresponsiveness (BHR) and asthma. METHODS: This prospective follow-up study involved schoolchildren from the Children's Health and Environment Research cohort with current rhinitis, which was defined based on parental-reported, physician-diagnosed rhinitis and symptoms of rhinitis in the previous 12 months...
July 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27134697/debates-in-allergy-medicine-specific-immunotherapy-in-children-with-atopic-dermatitis-the-con-view
#18
David N Ginsberg, Lawrence F Eichenfield
Atopic dermatitis (AD) is a common chronic skin condition in children that has a proven association with other atopic conditions and allergies. These associations, like the general pathophysiology of AD, are complex and not fully understood. While there is evidence for the efficacy of specific immunotherapy (SIT) in pediatric asthma and allergic rhinitis (AR), there is a lack of strong data to support its use in AD. IgE has been shown to be elevated in many patients with AD, but it is an unreliable biomarker due to variability and great fluctuation over time, poor positive predictive value for clinically relevant allergy, and poor correlation with disease state...
2016: World Allergy Organization Journal
https://www.readbyqxmd.com/read/27126728/response-to-nonallergenic-irritants-in-children-with-allergic-and-nonallergic-rhinitis
#19
Ji Hyeon Baek, Eunhae Cho, Mi Ae Kim, Seung Won Lee, Yu Sun Kang, Youn Ho Sheen, Hye Mi Jee, Young Ho Jung, Man Yong Han
PURPOSE: Nonallergenic irritants can aggravate the symptoms of rhinitis. We investigated the clinical responses of children with allergic rhinitis (AR) and nonallergic rhinitis (NAR) to nonallergenic irritants, and identified factors associated with these responses. METHODS: Children with chronic rhinitis (n=208) were classified as having AR or NAR based on the presence of aeroallergen-specific IgE. Healthy controls (n=24) were recruited for comparison. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines were used to classify patients, and their irritant score (0-21 points) and current symptom score (5-35 points) were measured...
July 2016: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/27035379/preschoolers-with-allergic-diseases-have-an-increased-risk-of-irritable-bowel-syndrome-when-reaching-school-age
#20
Teck-King Tan, An-Chyi Chen, Cheng-Li Lin, Te-Chun Shen, Tsai-Chung Li, Chang-Ching Wei
OBJECTIVES: To systemically investigate the risk of subsequent irritable bowel syndrome (IBS) in children with antecedent allergic diseases in a population-based case-control study in Taiwan. METHODS: We evaluated 11,242 children (age range: 7-18 years) with IBS and 44,968 age- and sex-matched control subjects who had been examined between 2000 and 2008. IBS odds ratios (ORs) were calculated for children with antecedent allergic diseases, including allergic conjunctivitis (AC), allergic rhinitis (AR), asthma, atopic dermatitis (AD), urticaria, and food allergy (FA)...
March 28, 2016: Journal of Pediatric Gastroenterology and Nutrition
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