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https://www.readbyqxmd.com/read/28635116/maternal-smoking-alcohol-and-caffeine-exposures-and-risk-of-hypospadias
#1
Suzan L Carmichael, Chen Ma, Gary M Shaw
BACKGROUND: We examined the association of hypospadias risk with maternal smoking and consumption of alcohol and caffeine. METHODS: We analyzed data from mothers of 2437 moderate/severe cases and 5472 nonmalformed controls born from 1997 to 2011 who participated in the National Birth Defects Prevention Study (NBDPS). Exposures were assessed by maternal telephone interviews. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs) adjusted for mother's age, parity, race-ethnicity, education, vitamin/mineral supplement intake, obesity, and study center...
June 21, 2017: Birth defects research
https://www.readbyqxmd.com/read/28634246/assisted-reproductive-techniques-and-risk-of-beckwith-wiedemann-syndrome
#2
Alessandro Mussa, Cristina Molinatto, Flavia Cerrato, Orazio Palumbo, Massimo Carella, Giuseppina Baldassarre, Diana Carli, Clementina Peris, Andrea Riccio, Giovanni Battista Ferrero
BACKGROUND AND OBJECTIVES: The emerging association of assisted reproductive techniques (ART) with imprinting disorders represents a major issue in the scientific debate on infertility treatment and human procreation. We studied the prevalence of Beckwith-Wiedemann syndrome (BWS) in children conceived through ART to define the specific associated relative risk. METHODS: Patients with BWS born in Piemonte, Italy, were identified and matched with the general demographic data and corresponding regional ART registry...
June 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28632498/can-early-ultrasonography-explain-the-lower-miscarriage-rates-in-twin-as-compared-to-singleton-pregnancies-following-assisted-reproduction
#3
Ana Póvoa, Alexandra Matias, Pedro Xavier, Isaac Blickstein
OBJECTIVE: To compare first trimester 2D conventional and 3D power Doppler angiography measures in twins and singletons following assisted reproduction. METHODS: We prospectively evaluated 50 singleton and 47 twin pregnancies that eventually ended in live births. Patients were recruited from a single assisted reproductive technology (ART) center with standard treatment protocols. Obstetric ultrasound was performed at 8-9 weeks +6 days. Intervillous flow, uteroplacental circulation and uterine artery pulsatility (PI) and resistance index (RI) using two-dimensional (2D) ultrasound examination were evaluated...
June 20, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28630744/maternal-predictors-of-neonatal-outcomes-after-emergency-cesarean-section-a-retrospective-study-in-three-rural-district-hospitals-in-rwanda
#4
Naome Nyirahabimana, Christine Minani Ufashingabire, Yihan Lin, Bethany Hedt-Gauthier, Robert Riviello, Jackline Odhiambo, Joel Mubiligi, Martin Macharia, Stephen Rulisa, Illuminee Uwicyeza, Patient Ngamije, Fulgence Nkikabahizi, Theoneste Nkurunziza
BACKGROUND: In sub-Saharan Africa, neonatal mortality post-cesarean delivery is higher than the global average. In this region, most emergency cesarean sections are performed at district hospitals. This study assesses maternal predictors for poor neonatal outcomes post-emergency cesarean delivery in three rural district hospitals in Rwanda. METHODS: This retrospective study includes a random sample of 441 neonates from Butaro, Kirehe and Rwinkwavu District Hospitals, born between 01 January and 31 December 2015...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28629584/association-of-vitamin-d-intake-and-serum-levels-with-fertility-results-from-the-lifestyle-and-fertility-study
#5
June L Fung, Terryl J Hartman, Rosemary L Schleicher, Marlene B Goldman
OBJECTIVE: To evaluate the role of vitamin D intake and serum levels on conception of clinical pregnancy and live birth. DESIGN: Prospective cohort study. SETTING: Academic medical centers. PATIENT(S): Healthy, nulliparous women, age 18-39 years, and their male partners. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Clinical pregnancy and live birth were compared between those who did or did not meet the vitamin D estimated average requirement (EAR) intake (10 μg/d) and with serum 25-hydroxyvitamin D (25(OH)D) considered at risk for inadequacy or deficiency (<50 nmol/L) or sufficient (≥50 nmol/L)...
June 16, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28629238/us-trends-in-abortion-and-preterm-birth
#6
Elena Rita Magro Malosso, Gabriele Saccone, Biagio Simonetti, Massimo Squillante, Vincenzo Berghella
BACKGROUND: A recent large meta-analysis concluded that prior surgical abortion was an independent risk factor for spontaneous preterm birth (PTB), while they found no significant correlation between PTB and medical abortion. OBJECTIVE: To evaluate the potential impact of changes in US abortion rates and practices on US incidence of PTB rate. STUDY DESIGN: This was an epidemiologic analysis of legal abortion and PTB data in the USA from 2003-2012...
June 19, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28628972/urinary-sexual-steroids-associated-with-bisphenol-a-bpa-exposure-in-the-early-infant-stage-preliminary-results-from-a-daishan-birth-cohort
#7
Heng Wang, Liangpo Liu, Jianyue Wang, Zhendong Tong, Jianbo Yan, Tongjie Zhang, Ying Qin, Tingting Jiang, Jianwen She, Heqing Shen
BACKGROUND: Many surveys have shown that older children are ubiquitously exposed to bisphenol A (BPA), and many laboratory studies have shown that BPA exposure has adverse effects related to estrogenic disruption, whereas the evidence in infants has not yet been observed. METHODS: Women in early pregnancy were recruited by the Maternal and Child Health and Family Planning Service Center, Daishan, China, from March 2012 to December 2014. After delivery, urine samples were collected from the diapers of 59 infants (0 to 6months of age)...
June 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28625180/abortion-and-subsequent-depressive-symptoms-an-analysis-of-the-national-longitudinal-study-of-adolescent-health
#8
A M Gomez
BACKGROUND: Twenty states currently require that women seeking abortion be counseled on possible psychological responses, with six states stressing negative responses. The majority of research finds that women whose unwanted pregnancies end in abortion do not subsequently have adverse mental health outcomes; scant research examines this relationship for young women. METHODS: Four waves of data from the National Longitudinal Study of Adolescent Health were analyzed...
June 19, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28622784/first-trimester-inter-and-intrafetal-size-discrepancies-in-bichorionic-twins-conceived-by-in%C3%A2-vitro-fertilization-can-it-predict-pregnancy-outcome
#9
Ron Bardin, Galia Oron, Yael Levy, Onit Sapir, Israel Meizner, Benjamin Fisch, Arnon Wiznitzer, Eran Hadar
OBJECTIVE: To evaluate the association between first-trimester inter- and intrafetal size discrepancies and pregnancy outcome, among bichorionic-biamniotic twins conceived by IVF. DESIGN: A retrospective study design was used. SETTING: Tertiary university-affiliated medical center. PATIENT(S): All women with a viable first-trimester bichorionic-biamniotic twin gestation, who conceived after IVF in 2007-2015. INTERVENTION(S): None...
June 13, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28622143/epidural-analgesia-at-trial-of-labor-after-cesarean-tolac-a-significant-adjunct-to-successful-vaginal-birth-after-cesarean-vbac
#10
Sorina Grisaru-Granovsky, Maayan Bas-Lando, Lior Drukker, Fred Haouzi, Rivka Farkash, Arnon Samueloff, Alexander Ioscovich
INTRODUCTION: Epidural analgesia has been considered a risk factor for labor dystocia at trial of labor after cesarean (TOLAC) and uterine rupture. We evaluated the association between exposure to epidural during TOLAC and mode of delivery and maternal-neonatal outcomes. MATERIALS AND METHODS: A single center retrospective study of women that consented to TOLAC within a strict protocol between 2006 and 2013. Epidural "users" were compared to "non-users". Primary outcome was the mode of delivery: repeat in-labor cesarean or vaginal birth after cesarean (VBAC)...
June 5, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28621803/absent-pulmonary-valve-syndrome-diagnosis-associations-and-outcome-in-71-prenatally-diagnosed-cases
#11
Roland Axt-Fliedner, Andrii Kurkevych, Maciej Slodki, Maria Respondek-Liberska, Katarzyna Zych-Krekora, Rüdiger Stressig, Jochen Ritgen, Guiseppe Rizzo, Martin Krapp, Luc de Catte, Gunther Mielke, Stephan Bosselmann, Mathias Meyer-Wittkopf, Andrea Kawecki, Aline Wolter, Marios Mamalis, Christian Enzensberger
OBJECTIVE: To analyze the spectrum of prenatally diagnosed absent pulmonary valve syndrome (APVS) and the outcome from diagnosis onwards. Fetuses with APVS and tetralogy of Fallot (TOF/APVS) and with APVS and intact ventricular septum (APVS/IVS) were included. METHOD: Multicenter retrospective study of the International Prenatal Cardiology Collaboration Group (IPCCG). Clinical and echocardiographic databases of nine referral centers were reviewed from 2012-2016...
June 16, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28619065/open-issues-in-mucopolysaccharidosis-type-i-hurler
#12
REVIEW
Rossella Parini, Federica Deodato, Maja Di Rocco, Edoardo Lanino, Franco Locatelli, Chiara Messina, Attilio Rovelli, Maurizio Scarpa
Mucopolysaccharidosis I-Hurler (MPS I-H) is the most severe form of a metabolic genetic disease caused by mutations of IDUA gene encoding the lysosomal α-L-iduronidase enzyme. MPS I-H is a rare, life-threatening disease, evolving in multisystem morbidity including progressive neurological disease, upper airway obstruction, skeletal deformity and cardiomyopathy. Allogeneic hematopoietic stem cell transplantation (HSCT) is currently the gold standard for the treatment of MPS I-H in patients diagnosed and treated before 2-2...
June 15, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28617244/continuity-of-care-in-infancy-and-early-childhood-health-outcomes
#13
Elizabeth Enlow, Molly Passarella, Scott A Lorch
BACKGROUND AND OBJECTIVES: Continuity of care is a key aspect of the patient-centered medical home and improves pediatric outcomes. Health care reform requires high-quality data to demonstrate its continued value. We hypothesized that increased provider continuity in infancy will reduce urgent health care use and increase receipt of preventive services in early childhood. METHODS: Continuity, using the Usual Provider of Care measure, was calculated across all primary care encounters during the first year of life in a prospectively-constructed cohort of 17 773 infants receiving primary care from birth through 3 years at 30 clinics...
June 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28617243/fingertip-capillary-malformation-and-associated-disorders-report-of-9-cases
#14
Juan Carlos López-Gutiérrez, Pedro Redondo, Marta Ivars
Although capillary malformations (CMs) are not usually serious health problems in themselves, they can occasionally be warning signs for syndromes with more serious or aggressive vascular malformations not readily apparent at birth or on initial examination. We describe a series of 9 patients with a common phenotype: (1) CM on the fingertips; (2) associated combined vascular (lymphatic-venous) malformations on the trunk and/or extremities; and (3) in some cases, partial overgrowth and asymmetry of the extremities...
June 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28617151/lithium-exposure-during-pregnancy-outcomes-for-women-who-attended-a-specialist-antenatal-clinic
#15
Jacqueline Frayne, Thinh Nguyen, Tabitha Mok, Yvonne Hauck, Helena Liira
INTRODUCTION: Lithium treatment in pregnancy represents a significant dilemma for women and treating health professionals alike. The complexity of risk-benefit analysis is impacted by limited information. METHODS: A cohort study of 33 women with severe mental illness, who were prescribed lithium at any time during the pregnancy, and gave birth between December 2007 and January 2015 at a specialist antenatal clinic in Western Australia. A descriptive comparison for women who continued lithium throughout pregnancy, and those who ceased on discovery of pregnancy was undertaken examining demographic, obstetric, neonatal and psychiatric variables...
June 15, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28617057/preliminary-evaluation-of-a-point-of-care-testing-device-sicklescan%C3%A2-in-screening-for-sickle-cell-disease
#16
Maxwell M Nwegbu, Hezekiah A Isa, Biyaya B Nwankwo, Chinedu C Okeke, Uduak J Edet-Offong, Norah O Akinola, Adekunle D Adekile, John C Aneke, Emmanuel C Okocha, Thomas Ulasi, Usman Abjah, Ngozi I Ugwu, Angela A Okolo, Anazoeze Madu, Ifeoma Emodi, Ahmed Girei, Taiwo M Balogun, Ijeoma N Diaku-Akinwumi, Chinatu Ohiaeri, Biobele J Brown, John A Olaniyi, Abdulaziz Hassan, Sani Awwalu, Dorothy A Okoh, Obiageli E Nnodu
Sickle cell disease affects about 150,000 births annually in Nigeria. Early diagnosis is hampered by factors such as centralized and urban localization of laboratories, high cost of diagnostic equipment and inadequate skilled manpower to operate them. The need for a low-cost, portable, easy-to-use diagnostic test for sickle cell disease is critical, especially in resource-poor countries. In this study, we evaluated the performance characteristics of a novel point-of-care testing device (SickleSCAN™), and its acceptability and feasibility, as a possible screening tool for sickle cell disease...
June 15, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28616424/evaluation-of-1-year-old-children-development-in-isfahan-city-and-its-effective-factors-using-ages-and-stages-questionnaire-in-2014
#17
Mehri Rejali, Soheila Pahlavni, Akbar Hassanzadeh
BACKGROUND AND AIMS: Attention to the development of children as the future generation that leads to the upbringing of productive human resources is an important subject. Development has dimensions that a child should acquire the skills related to them in proper age. Otherwise, he may be affected by developmental delays. There are different factors influencing children's developmental delays and this study is carried out to evaluate the developmental conditions of 1-year-old children in the Isfahan and its effective factors...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28611102/effect-on-neonatal-mortality-of-newborn-infection-management-at-health-posts-when-referral-is-not-possible-a-cluster-randomized-trial-in-rural-ethiopia
#18
Tedbabe Degefie Hailegebriel, Brian Mulligan, Simon Cousens, Bereket Mathewos, Steve Wall, Abeba Bekele, Jeanne Russell, Deborah Sitrin, Biruk Tensou, Joy Lawn, Joseph de Graft Johnson, Hailemariam Legesse, Sirak Hailu, Assaye Nigussie, Bogale Worku, Abdullah Baqui
BACKGROUND: The World Health Organization recently provided guidelines for outpatient treatment of possible severe bacterial infections (PSBI) in young infants, when referral to hospital is not feasible. This study evaluated newborn infection treatment at the most peripheral level of the health system in rural Ethiopia. METHODS: We performed a cluster-randomized trial in 22 geographical clusters (11 allocated to intervention, 11 to control). In both arms, volunteers and government-employed Health Extension Workers (HEWs) conducted home visits to pregnant and newly delivered mothers; assessed newborns; and counseled caregivers on prevention of newborn illness, danger signs, and care seeking...
June 12, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/28608406/pregnancy-in-cadasil
#19
I Donnini, V Rinnoci, S Nannucci, R Valenti, F Pescini, G Mariani, S Bianchi, M T Dotti, A Federico, D Inzitari, L Pantoni
OBJECTIVES: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebral small vessel disease caused by NOTCH3 gene mutations. CADASIL women are frequently considered at high risk of systemic vascular events during pregnancy and often prescribed with antithrombotic drugs. This decision is not evidence-based considering the lack of data about pregnancy outcome in CADASIL. We describe our experience on pregnancy in CADASIL patients...
June 12, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28607653/the-effect-of-a-self-care-program-based-on-the-teach-back-method-on-the-postpartum-quality-of-life
#20
Fatemeh Ghiasvand, Hedyeh Riazi, Sepideh Hajian, Elahe Kazemi, Armin Firoozi
BACKGROUND: The postpartum period is a critical stage of life with major changes in the quality of life. Therefore, special consideration is needed to this issue. OBJECTIVE: To determine the effect of a self-care program based on the Teach Back method on the postpartum quality of life. METHODS: This experimental study was conducted on eighty postpartum women who had given birth in health centers across Darreh Shahr County, Ilam Province, Iran in 2016...
April 2017: Electronic Physician
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