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https://www.readbyqxmd.com/read/29241214/nasalance-variability-in-3-to-5-year-old-children-during-production-of-speech-stimulus-in-three-vowel-contexts
#1
Seunghee Ha, Ilsan Shin
OBJECTIVE: The purpose of this study was to determine whether age and vowel contexts influence test-retest nasalance score variability in typically developing Korean children. PARTICIPANTS: Forty-five 3- to 5-year-old children with normal speech and resonance participated in the study. METHODS: All subjects were asked to repeat three 4-syllable speech stimuli in high, low, or mixed vowel contexts twice after the examiner. An immediate test-retest nasalance score was assessed with no headgear change...
December 14, 2017: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/29241196/calycosin-inhibits-the-migration-and-invasion-of-human-breast-cancer-cells-by-down-regulation-of-foxp3-expression
#2
Shuangxi Li, Yafei Wang, Chan Feng, Guoli Wu, Yu Ye, Jing Tian
BACKGROUND/AIMS: Calycosin, a phytoestrogenic compound, has recently emerged as a promising antitumor drug. It has been shown that calycosin suppresses growth and induces apoptosis of breast cancer cells. However, the effect of calycosin on migration and invasion of breast cancer cells and the underlying molecular mechanisms have not been elucidated. METHODS: Human breast cancer cells MCF-7 and T47D were treated with, or without, different doses (0, 6.25, 12.5, 25, 50, 100 or 150 μM) of calycosin, and the viability of different groups was determined by MTT assay...
December 6, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29241108/the-efficacy-of-posterior-hemivertebra-resection-with-lumbosacral-fixation-and-fusion-in-the-treatment-of-congenital-scoliosis-a-more-than-2-year-follow-up-study
#3
Qiunan Lyu, Bowen Hu, Chunguang Zhou, Limin Liu, Yueming Song, Xi Yang, Liang Wang, Lei Wang
OBJECTIVE: Hemivertebrae (HV) located at the lower lumbar or lumbosacral region often produce early trunk imbalance and long compensatory curves. Because of the biomechanical characteristics of the lumbosacral junction, the rate of instrumentation failures at the region has always been high. Our study aimed to evaluate the results of posterior HV resection with lumbosacral fixation and fusion in the treatment of congenital scoliosis and to make a preliminary analysis of the possible risk factors for instrument failures...
December 9, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29241105/how-alcohol-use-problem-severity-affects-the-outcome-of-brief-intervention-delivered-in-person-versus-through-computer-generated-feedback-letters
#4
Sophie Baumann, Beate Gaertner, Katja Haberecht, Gallus Bischof, Ulrich John, Jennis Freyer-Adam
OBJECTIVE: The aim was to test if people with different alcohol use problem severity benefitted differentially from brief alcohol interventions delivered in-person versus through computer-generated feedback letters. METHODS: Nine hundred sixty-one 18-64year old general hospital inpatients with at-risk alcohol use (mean age=40.9years [standard deviation=14.1], 75% men) were randomized to a) in-person counseling, b) computer-generated individualized feedback letters, or c) assessment only...
December 9, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29241090/attachment-style-and-filial-obligation-in-the-burden-of-caregivers-of-dementia-patients
#5
Juwon Lee, Bo Kyung Sohn, Hyunjoo Lee, Su Jeong Seong, Soowon Park, Jun-Young Lee
Insecure attachment styles have been known to predict greater burden in caregivers of dementia patients. However, it has not been tested how filial obligation, which refers to one's sense of duty on helping elderly parents and is especially pronounced in Asian cultures, is involved in that relationship. We sought to identify whether the association between attachment style and caregiver burden differs according to the degree of filial obligation in caregivers of dementia patients. To assess filial obligation in Korean participants, a Korean filial obligation measure was developed...
December 6, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29240858/a-novel-multifactorial-approach-to-developing-mild-laundry-detergents-and-assessing-their-relative-mildnes
#6
Joseph F Fowler, Matthew J Zirwa J Zirwas, Lisa Napolitano, Meghan Russell, Janet Coope-Epstein
<p>INTRODUCTION: Dermatologists are becoming more aware of the irritant and allergic potential of laundry detergents that incorporate harsh surfactants and potentially sensitizing ingredients. It is difficult however for the physician to distinguish one laundry detergent from another because the only distinguishing feature advertised tends to be the lack of dyes and fragrances.</p> <p>DESIGN: A new objective method was developed for measuring the harshness of laundry detergents using a three-pronged laboratory testing approach consisting of zein, corneosurfametry, and cytokine testing...
December 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29240838/recognized-focused-practice-does-sub-specialty-designation-offer-value-to-the-neurosurgeon
#7
Maya A Babu, Linda M Liau, Fredric B Meyer
Vehicles for life-long assessment such as Maintenance of Certification tend to focus on generalist neurosurgical knowledge. However, as neurosurgeons advance in their careers, they tend to narrow their practice and increase volumes in certain specific types of operations. Failing to test the type of procedures most relevant to the practitioner is a lost opportunity to improve the knowledge and practice of the individual neurosurgeon. In this study, we assess the neurosurgical community's appetite for designations of board-recognized Recognized Focused Practice (RFP)...
2017: PloS One
https://www.readbyqxmd.com/read/29240805/poly-victimization-in-a-norwegian-adolescent-population-prevalence-social-and-psychological-profile-and-detrimental-effects
#8
Svein Mossige, Lihong Huang
BACKGROUND: This study focuses on poly-victimization, with the aim of providing a realistic estimation of the prevalence of lifetime victimization in a Norwegian adolescent population (ages 18-19 years). METHODS: Based upon the concept from previous research, we applied measures of child poly-victimization on Norwegian data obtained from a national youth survey in 2015 (N = 4,531) to arrive at an estimation of its prevalence. We used variables that measure individual characteristics such as gender and educational aspiration and socio-economic factors such as parents' education level and home economic situation to derive a social and psychological profile of victimization and poly-victimization among young people...
2017: PloS One
https://www.readbyqxmd.com/read/29240789/how-to-quantitatively-evaluate-safety-of-driver-behavior-upon-accident-a-biomechanical-methodology
#9
Wen Zhang, Jieer Cao, Jun Xu
How to evaluate driver spontaneous reactions in various collision patterns in a quantitative way is one of the most important topics in vehicle safety. Firstly, this paper constructs representative numerical crash scenarios described by impact velocity, impact angle and contact position based on finite element (FE) computation platform. Secondly, a driver cabin model is extracted and described in the well validated multi-rigid body (MB) model to compute the value of weighted injury criterion to quantitatively assess drivers' overall injury under certain circumstances...
2017: PloS One
https://www.readbyqxmd.com/read/29240786/time-trend-analysis-2009-2016-of-antimicrobial-susceptibility-in-neisseria-gonorrhoeae-isolated-in-italy-following-the-introduction-of-the-combined-antimicrobial-therapy
#10
Paola Stefanelli, Maria Fenicia Vescio, Maria Paola Landini, Ivano Dal Conte, Alberto Matteelli, Antonio Cristaudo, Marina Gaino, Marco Cusini, Anna Maria Barbui, Antonella Mencacci, Rosella De Nittis, Valeria Ghisetti, Elena Stroppiana, Anna Carannante
INTRODUCTION: Neisseria gonorrhoeae (NG) antimicrobial susceptibility trends to azithromycin, cefixime and ceftriaxone were analyzed, from 2009 to 2016, to monitor changing antimicrobial susceptibility concomitant with the change in prescribing practice in 2012 from cefixime, or ceftriaxone, to ceftriaxone plus azithromycin. Patient characteristics predictive to be infected by antibiotic resistant N. gonorrhoeae were estimated. Finally, the protocol for the treatment of gonorrhoea, in comparison with the international guidelines, was also evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/29240657/inequalities-in-health-services-usage-in-a-national-health-system-scheme-the-case-of-a-southern-social-european-region
#11
Maite Morteruel, Elena Rodriguez-Alvarez, Unai Martin, Amaia Bacigalupe
BACKGROUND: Health services can reduce inequalities caused by other determinants of health or increase them due to the effect of the inverse care law-the principle that the availability of good quality care tends to vary inversely with the need for it in the population served. OBJECTIVE: The purpose of the research was to describe inequalities in the use of nursing services, medical services in primary care, specialist care, and services not fully covered by the Basque public health system in Spain...
January 2018: Nursing Research
https://www.readbyqxmd.com/read/29240601/efficacy-of-transanal-drainage-tube-placement-after-modified-posterior-pelvic-exenteration-for-primary-ovarian-cancer
#12
Kazuyoshi Kato, Kohei Omatsu, Maki Matoda, Hidetaka Nomura, Sanshiro Okamoto, Hiroyuki Kanao, Kuniko Utsugi, Nobuhiro Takeshima
OBJECTIVE: The aim of this study was to investigate the clinical usefulness of the placement of a transanal drainage tube (TDT) to prevent anastomotic leakage after a modified posterior pelvic exenteration (MPPE) for the treatment of primary ovarian cancer. METHODS: We performed a retrospective review of all the consecutive patients who had undergone an MPPE for primary ovarian, tubal, or peritoneal cancer between October 2012 and November 2016 at our institution...
December 13, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29240273/endothelial-dysfunction-may-promote-keloid-growth
#13
Chikage Noishiki, Gen Takagi, Yoshiaki Kubota, Rei Ogawa
Keloid is a cutaneous fibroproliferative disorder. It results from impaired wound healing that generates persistent inflammation and extensive deposition of collagen fibers in the wound/scar. Keloids tend to be worse in hypertensive patients. The present prospective cross-sectional study assessed whether endothelial dysfunction, which occurs in hypertension, associates with keloid formation and progression. This study included randomly-selected patients with keloids who were assessed for surgical keloid treatment in 2013-2014...
December 14, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29240194/tens-of-hertz-narrow-linewidth-laser-based-on-stimulated-brillouin-and-rayleigh-scattering
#14
Shihong Huang, Tao Zhu, Guolu Yin, Tianyi Lan, Ligang Huang, Fuhui Li, Yongzhong Bai, Dingrong Qu, Xianbin Huang, Feng Qiu
We proposed and demonstrated a linewidth compression method of a laser based on stimulated Brillouin scattering (SBS) and a Rayleigh backscattering structure (RBS). The relationship between the output SBS laser linewidth and the input pump linewidth was studied theoretically and experimentally. It is shown that the narrower linewidth of the pump laser leads to the narrower bandwidth of the SBS gain and, finally, the bandwidth of the SBS will tend to its intrinsic value as the linewidth of a pump laser narrower than 10 kHz; then the linewidth of an SBS fiber ring laser would tend to 200 Hz...
December 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29240126/analysis-of-long-term-visual-quality-with-numerical-3d-ray-tracing-after-corneal-crosslinking-treatment
#15
Staffan Schedin, Per Hallberg, Anders Behndig
A numerical 3D ray tracing model was used to evaluate the long-term visual effects of two regimens of corneal crosslinking (CXL) treatment of 48 patients with the corneal degeneration keratoconus. The 3D ray tracing analyses were based on corneal elevation data measured by Scheimpflug photography. Twenty-two patients were treated with standard CXL applied uniformly across the corneal surface, whereas 26 patients underwent a customized, refined treatment only at local zones on the cornea (photorefractive intrastromal CXL; PiXL)...
December 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29240077/clinically-impactful-differences-in-variant-interpretation-between-clinicians-and-testing-laboratories-a-single-center-experience
#16
Austin Bland, Elizabeth A Harrington, Kyla Dunn, Mitchel Pariani, Julia C K Platt, Megan E Grove, Colleen Caleshu
PurposeTo describe the frequency and nature of differences in variant classifications between clinicians and genetic testing laboratories.MethodsRetrospective review of variants identified through genetic testing ordered in routine clinical care by clinicians in the Stanford Center for Inherited Cardiovascular Disease. We compared classifications made by clinicians, the testing laboratory, and other laboratories in ClinVar.ResultsOf 688 laboratory classifications, 124 (18%) differed from the clinicians' classifications...
December 14, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29239976/abnormalities-of-p300-before-and-after-antidepressant-treatment-in-depression-an-erp-sloreta-study
#17
Lina Zhou, Gaohua Wang, Huiling Wang
Despite a wide range of reports on depression-induced P300 changes, it is still debatable whether P300 can return to a pattern characteristic of healthy individuals following antidepressant treatment. Thus, the present study aims to compare P300 and its underlying neural activation in depressed patients before and after antidepressant treatment to explore the brain regions related to pathogenesis and to evaluate the prognosis after treatment. P300 was evoked by the oddball auditory paradigm and collected from 14 sex-matched, age-matched, and education level-matched patients and controls...
December 12, 2017: Neuroreport
https://www.readbyqxmd.com/read/29239890/omega-3-decreases-interleukin-6-levels-in-hiv-and-hhv-8-co-infected-patients-results-from-a-randomized-supplementation-trial-in-uganda
#18
Anna E Coghill, Jeanette M Schenk, Zeina Mahkoul, Jackson Orem, Warren Phipps, Corey Casper
OBJECTIVE: Kaposi sarcoma (KS) is an HIV-associated malignancy caused by human herpesvirus-8 that occurs at highest incidence in sub-Saharan Africa. KS patients often present with inflammatory symptoms associated with higher mortality. DESIGN: We conducted a double-blind, randomized, placebo-controlled study in Uganda to test whether omega-3 (ω-3) supplementation could reduce inflammation in HIV and HHV-8 co-infected adults ≥ 18 years of age. Patients with acute illness, AIDS, or advanced KS were ineligible, as were pregnant women...
December 12, 2017: AIDS
https://www.readbyqxmd.com/read/29239806/development-of-postural-control-and-maturation-of-sensory-systems-in-children-of-different-ages-a-cross-sectional-study
#19
Cristina Dos Santos Cardoso de Sá, Catarina Costa Boffino, Renato Teodoro Ramos, Clarice Tanaka
OBJECTIVE: To evaluate the stability, postural adjustments and contributions of sensory information for postural control in children. METHODS: 40 boys and 40 girls were equally divided into groups of 5, 7, 9 and 12 years (G5, G7, G9 and G12). All children were submitted to dynamic posturography using a modified sensory organization test, using four sensory conditions: combining stable or sway referencing platform with eyes opened, or closed. The area and displacements of the center of pressure were used to determine stability, while the adjustments were used to measure the speed of the center of pressure displacements...
November 8, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29239695/gender-differences-in-romantic-relationship-memories-who-remembers-who-cares
#20
Diane Holmberg, Tabatha M Thibault, Jennifer D Pringle
Two studies were conducted to assess patterns of gender differences in memory for romantic relationship events. Results suggested that people believe that women have better memory for romantic relationship events than men, that better relationship memory predicts higher levels of relationship well-being, and that the association between relationship memory and relationship well-being is somewhat stronger for women than for men. Women did tend to have somewhat better relationship memory than men, as assessed via subjective reports from both partners in mixed-sex relationships, and via the number of details partners provided when asked to recall a specific relationship event (i...
December 14, 2017: Memory
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