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https://www.readbyqxmd.com/read/28823132/a-short-term-supranutritional-vitamin-e-supplementation-alleviated-respiratory-alkalosis-but-did-not-reduce-oxidative-stress-in-heat-stressed-pigs
#1
Fan Liu, Pietro Celi, Surinder Singh Chauhan, Jeremy James Cottrell, Brian Joseph Leury, Frank Rowland Dunshea
Objective: Heat stress (HS) triggers oxidative stress and respiratory alkalosis in pigs. The objective of this experiment was to study whether a short-term supranutritional amount of dietary vitamin E (VE) can mitigate oxidative stress and respiratory alkalosis in heat-stressed pigs. Methods: A total of 24 pigs were given either a control diet (17 IU/kg VE) or a high VE (200 IU/kg VE; HiVE) diet for 14 d, then exposed to thermoneutral (TN; 20°C, 45% humidity) or HS (35°C, 35-45% humidity, 8 h daily) conditions for 7 d...
August 16, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28823126/current-status-and-prospective-of-in-feed-additive-antibiotics-in-the-individual-stage-of-the-pork-production
#2
Junyou Li
Antibiotics have long been of great benefit for people, both in the medical treatment of human disease and in animal food that improves the growth performance and feed utilization during animal production. Antibiotics as in-feed supplements affect all stages of pork production, including the gestation, nursing, growing, and finishing stages, although the effects show stage-dependent differences. However, the use of antibiotics in animal feed has become a worldwide concern. This review describes why sub-therapeutic levels of antibiotic additives in animal feed have become an integral part of animal feeding programs for more than 70 years, particularly in pork production...
August 16, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28823122/genetic-analysis-of-milk-production-traits-of-tunisian-holsteins-using-random-regression-test-day-model-with-legendre-polynomials
#3
Hafedh Ben Zaabza, Abderrahmen Ben Gara, Boulbaba Rekik
Objective: The objective of this study was to estimate genetic parameters of milk, fat, and protein yields within and across lactations in Tunisian Holsteins using a random regression test-day model. Methods: A random regression multiple trait multiple lactation test-day (TD) model was used to estimate genetic parameters in the Tunisian dairy cattle population. Data were TD yields of milk, fat, and protein from the first three lactations. Random regressions were modeled with third-order Legendre polynomials for the additive genetic, and permanent environment effects...
August 16, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28823017/near-infrared-spectroscopy-monitoring-during-immediate-transition-after-birth-time-to-obtain-cerebral-tissue-oxygenation
#4
Evelyn Ziehenberger, Berndt Urlesberger, Corinna Binder-Heschl, Bernhard Schwaberger, Nariae Baik-Schneditz, Gerhard Pichler
Feasibility of cerebral tissue oxygenation measurements immediately after birth has been published starting with first values 2 min after birth. Aim of this study was to evaluate, the time periods from birth and from arrival at the resuscitation table to obtain the first cerebral tissue oxygenation values with two different near infrared spectroscopy (NIRS) devices. The present study is an analysis of exploratory parameters of two prospective observational studies. Cerebral tissue oxygen saturation was measured by the NIRO 200NX measuring "cerebral-tissue-oxygenation-index" (cTOI) or the INVOS5100C measuring "cerebral-regional-oxygen-saturation" (crSO2)...
August 19, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28822954/the-variability-of-hepatitis-b-envelope-is-associated-with-hbs-antigen-persistence-in-either-chronic-or-acute-hbv-genotype-a-infection
#5
Marine Eschlimann, Brice Malvé, Aurélie Velay, Honorine Fenaux, Sibel Berger, Jean-Pol Frippiat, Fabien Zoulim, Mouni Bensenane, Jean-Pierre Bronowicki, François Goehringer, Thierry May, Hélène Jeulin, Evelyne Schvoerer
BACKGROUND: More than 240 million people are chronically infected by hepatitis B virus (HBV) worldwide. Envelope proteins play a crucial role in viral cellular entry and immune recognition. The loss of HBs antigen (HBsAg) correlated with a good clinical prognosis is rarely achieved with or without treatment (3-16%). OBJECTIVES: HBV envelope variability was investigated according to HBsAg persistence. STUDY DESIGN: The cohort consisted of 15 HBV genotype A-infected patients divided into "resolvers", with HBsAg clearance, and "non-resolvers", with HBsAg persistence and in subgroups: acute (n=5, AHBV) or chronic infection (n=4, CHBV) and HBV/HIV coinfection (n=6, CHBV/HIV)...
August 5, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28822902/pregnancy-outcome-is-influenced-by-luteal-area-during-diestrus-before-successful-insemination-but-not-by-milk-production-level
#6
H Berger, M Lietzau, A Tichy, K Herzog
The objective was to compare luteal area (LA), luteal blood flow (LBF), and progesterone (P4) concentration before and after artificial insemination (AI) in pregnant and open cows in the diestrus preceding insemination and during the first 21 d after insemination. A number of 119 multiparous German Holstein cows were examined using B-mode and color Doppler sonography in diestrus (15-5 d before AI) and on days 7, 14, and 21 post insemination (pi). Blood samples for determination of P4 concentration were collected at each examination...
April 14, 2017: Theriogenology
https://www.readbyqxmd.com/read/28822545/effects-of-the-dose-and-viability-of-saccharomyces-cerevisiae-2-ruminal-fermentation-performance-of-lactating-dairy-cows-and-correlations-between-ruminal-bacteria-abundance-and-performance-measures
#7
Y Jiang, I M Ogunade, K G Arriola, M Qi, D Vyas, C R Staples, A T Adesogan
This study examined effects of the dose and viability of supplemented Saccharomyces cerevisiae yeast strain YE1496 on ruminal fermentation and performance of lactating dairy cows. A second objective was to examine correlations between ruminal bacteria abundance and performance measures. Four ruminally cannulated lactating cows (284 ± 18 days in milk) were assigned randomly to 1 of 4 treatment sequences in a 4 × 4 Latin square experimental design using four 21-d experimental periods. Cows were fed a nonacidotic total mixed ration comprising 22...
August 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28822541/only-7-of-the-variation-in-feed-efficiency-in-veal-calves-can-be-predicted-from-variation-in-feeding-motivation-digestion-metabolism-immunology-and-behavioral-traits-in-early-life
#8
M S Gilbert, J J G C van den Borne, C G van Reenen, W J J Gerrits
High interindividual variation in growth performance is commonly observed in veal calf production and appears to depend on milk replacer (MR) composition. Our first objective was to examine whether variation in growth performance in healthy veal calves can be predicted from early life characterization of these calves. Our second objective was to determine whether these predictions differ between calves that are fed a high- or low-lactose MR in later life. A total of 180 male Holstein-Friesian calves arrived at the facilities at 17 ± 3...
August 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28822408/-the-application-of-artificial-neural-network-on-the-assessment-of-lexical-tone-production-of-pediatric-cochlear-implant-users
#9
Y T Mao, Z M Chen, L Xu
Objective: The present study was carried out to explore the tone production ability of the Mandarin-speaking children with cochlear implants (CI) by using an artificial neural network model and to examine the potential contributing factors underlining their tone production performance. The results of this study might provide useful guidelines for post-operative rehabilitation processes of pediatric CI users. Methods: Two hundred and seventy-eight prelingually deafened children who received unilateral CI participated in this study...
August 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28822309/nature-based-solutions-to-promote-human-resilience-and-wellbeing-in-cities-during-increasingly-hot-summers
#10
Angelo Panno, Giuseppe Carrus, Raffaele Lafortezza, Luigi Mariani, Giovanni Sanesi
Air temperatures are increasing because of global climate change. A warming phenomenon strongly related to global climate change is the urban heat island. It has been shown that the hotter temperatures occurring in cities during the summer negatively affect human wellbeing, but little is known about the potential mechanisms underlying the relationships between hotter temperatures, cognitive psychological resources and wellbeing. The aim of the present research is to understand whether, and how, spending time in urban green spaces, which can be considered as a specific kind of Nature-Based Solution (NBS), helps the recovery of cognitive resources and wellbeing...
August 16, 2017: Environmental Research
https://www.readbyqxmd.com/read/28822149/-ecology-suitability-study-of-ephedra-intermedia
#11
Xiao-Hui Ma, You-Yuan Lu, De-Dong Huang, Tian-Tian Zhu, Pei-Lin Lv, Ling Jin
The study aims at predicting ecological suitability of Ephedra intermedia in China by using maximum entropy Maxent model combined with GIS, and finding the main ecological factors affecting the distribution of E. intermedia suitability in appropriate growth area. Thirty-eight collected samples of E. intermedia and E. intermedia and 116 distribution information from CVH information using ArcGIS technology were analyzed. MaxEnt model was applied to forecast the E. intermedia in our country's ecology. E. intermedia MaxEnt ROC curve model training data and testing data sets the AUC value was 0...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28822068/polyethylene-damage-increases-with-varus-implant-alignment-in-posterior-stabilized-and-constrained-condylar-knee-arthroplasty
#12
Zhichang Li, Christina I Esposito, Chelsea N Koch, Yuo-Yu Lee, Douglas E Padgett, Timothy M Wright
BACKGROUND: Implant malalignment in primary TKA has been reported to increase stresses placed on the bearing surfaces of implant components. We used a longitudinally maintained registry coupled with an implant retrieval program to consider whether preoperative, postoperative, or prerevision malalignment was associated with increased risk of revision surgery after TKA. QUESTIONS/PURPOSES: (1) What is the relative polyethylene damage on medial and lateral compartments of the tibial plateaus from revised TKAs? (2) Does coronal TKA alignment affect implant performance, such that TKAs aligned in varus are predisposed to experience increased polyethylene damage? (3) Does TKA alignment differ between postoperative and prerevision radiographs, and if so, what does this difference suggest about the mechanical contact load placed on a knee with a TKA? METHODS: Between 2007 and 2012, we performed 18,065 primary TKAs at our institution...
August 18, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28822041/two-species-migration-and-clustering-in-two-dimensional-domains
#13
Lawrence Kurowski, Andrew L Krause, Hanako Mizuguchi, Peter Grindrod, Robert A Van Gorder
We extend two-species models of individual aggregation or clustering to two-dimensional spatial domains, allowing for more realistic movement of the populations compared with one spatial dimension. We assume that the domain is bounded and that there is no flux into or out of the domain. The motion of the species is along fitness gradients which allow the species to seek out a resource. In the case of competition, species which exploit the resource alone will disperse while avoiding one another. In the case where one of the species is a predator or generalist predator which exploits the other species, that species will tend to move toward the prey species, while the prey will tend to avoid the predator...
August 18, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28821961/postmortem-evaluation-of-cholesterol-triglyceride-and-apolipoprotein-levels
#14
Charlotte Girard, Maria Pia Scarpelli, Camilla Tettamanti, Cristian Palmiere
Cholesterol and triglyceride levels have been analyzed in the forensic setting and their values correlated with atherosclerotic lesions found at autopsy and histology. Nevertheless, the results of these investigations have provided diverging information on postmortem molecule stability and postmortem measurement reliability. The aim of this study was to determine triglycerides, total cholesterol, low-density and high-density lipoprotein cholesterol, apolipoprotein B100, and apolipoprotein A-I in antemortem and postmortem serum samples in a series of cases (N = 10, including cardiac and noncardiac deaths) that underwent forensic investigations and had both samples available, measure the same molecules in postmortem serum from femoral blood and pericardial and pleural fluids (N = 39, including cardiac and noncardiac deaths), and evaluate whether different levels of these molecules could be observed in cases characterized by different degrees of coronary artery atherosclerosis (N = 39, including cardiac and noncardiac deaths)...
August 18, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28821879/musashi-1-enhances-glioblastoma-cell-migration-and-cytoskeletal-dynamics-through-translational-inhibition-of-tensin3
#15
Hsiao-Yun Chen, Liang-Ting Lin, Mong-Lien Wang, Benoit Laurent, Chih-Hung Hsu, Chih-Ming Pan, Wan-Ru Jiang, Pau-Yuan Chen, Hsin-I Ma, Yi-Wei Chen, Pin-I Huang, Arthur Chiou, Shih-Hwa Chiou
The RNA-binding protein Musashi-1 (MSI1) exerts essential roles in multiple cellular functions, such as maintenance of self-renewal and pluripotency of stem cells. MSI1 overexpression has been observed in several tumor tissues, including glioblastoma (GBM), and is considered as a well-established marker for tumor metastasis and recurrence. However, the molecular mechanisms by which MSI1 regulates cell migration are still undetermined. Here we reported that MSI1 alters cell morphology, promotes cell migration, and increases viscoelasticity of GBM cells...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821744/exploring-the-sequence-based-prediction-of-folding-initiation-sites-in-proteins
#16
Daniele Raimondi, Gabriele Orlando, Rita Pancsa, Taushif Khan, Wim F Vranken
Protein folding is a complex process that can lead to disease when it fails. Especially poorly understood are the very early stages of protein folding, which are likely defined by intrinsic local interactions between amino acids close to each other in the protein sequence. We here present EFoldMine, a method that predicts, from the primary amino acid sequence of a protein, which amino acids are likely involved in early folding events. The method is based on early folding data from hydrogen deuterium exchange (HDX) data from NMR pulsed labelling experiments, and uses backbone and sidechain dynamics as well as secondary structure propensities as features...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821677/disruption-of-m1-activity-during-performance-plateau-impairs-consolidation-of-motor-memories
#17
Raphaël Hamel, Maxime Trempe, Pierre-Michel Bernier
Upon exposure to a new sensorimotor relationship, motor behaviors iteratively change early in adaptation, but eventually stabilize as adaptation proceeds. Behavioral work suggests that motor memory consolidation is initiated upon the attainment of asymptotic levels of performance. Separate lines of evidence point to a critical role of the primary motor cortex (M1) in consolidation. However, a causal relationship between M1 activity during asymptote and consolidation has yet to be demonstrated. The present study investigated this issue in male and female participants using single-pulse transcranial magnetic stimulation (TMS) to interfere with post-movement activity in M1 in two behavioral phases of a ramp-and-hold visuomotor adaptation paradigm...
August 18, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821655/goal-directed-visual-processing-differentially-impacts-human-ventral-and-dorsal-visual-representations
#18
Maryam Vaziri-Pashkam, Yaoda Xu
Recent studies have challenged the ventral/"what" and dorsal/"where" two-visual-processing-pathway view by showing the existence of "what" and "where" information in both pathways. Is the two-pathway distinction still valid? Here, we examined how goal-directed visual information processing may differentially impact visual representations in these two pathways. Using fMRI and MVPA, in three experiments on human participants (57% females), by manipulating whether color or shape were task relevant and how they were conjoined, we examined shape-based object category decoding in occipito-temporal and parietal regions...
August 14, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821400/alzheimer-s-disease-as-oligomeropathy
#19
REVIEW
Kenjiro Ono
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder and is characterized by pathological aggregates of amyloid β-protein (Aβ) and tau protein. On the basis of genetic evidence, biochemical data, and animal models, Aβ has been suggested to be responsible for the pathogenesis of AD (the amyloid hypothesis). Aβ molecules tend to aggregate to form oligomers, protofibrils, and mature fibrils. Although mature fibrils in the final stage have been thought to be the cause of AD pathogenesis, recent studies using synthetic Aβ peptides, a cell culture model, Aβ precursor protein transgenic mice models, and human samples, such as cerebrospinal fluids and postmortem brains of AD patients, suggest that pre-fibrillar forms (oligomers of Aβ) are more deleterious than are extracellular fibril forms...
August 15, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28821298/efficacy-of-a-polyvalent-immersion-vaccine-against-flavobacterium-psychrophilum-and-evaluation-of-immune-response-to-vaccination-in-rainbow-trout-fry-onchorynchus-mykiss-l
#20
R Hoare, T P H Ngo, K L Bartie, A Adams
Rainbow trout fry syndrome (RTFS) is a disease caused by the Gram-negative bacterium Flavobacterium psychrophilum, responsible for significant economic losses in salmonid aquaculture worldwide. The diversity of F. psychrophilum isolates and the inherent difficulties in vaccinating juvenile fish has hampered the development of a vaccine for RTFS. Disease episodes tend to occur between 10-14 °C with necrotic lesions often seen on the skin surrounding the dorsal fin and tail. At present no commercial vaccines are available for RTFS in the UK, leaving antibiotics as the only course of action to control disease outbreaks...
August 18, 2017: Veterinary Research
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