Yeganeh Mehrani, Solmaz Morovati, Tahmineh Tajik, Soroush Sarmadi, Ali Bitaraf, Zahra Sourani, Mohammad Shahverdi, Helia Javadi, Julia E Kakish, Byram W Bridle, Khalil Karimi
The skin is a dynamic organ with a complex immune network critical for maintaining balance and defending against various pathogens. Different types of cells in the skin, such as mast cells (MCs) and group 2 innate lymphoid cells (ILC2s), contribute to immune regulation and play essential roles in the early immune response to various triggers, including allergens. It is beneficial to dissect cell-to-cell interactions in the skin to elucidate the mechanisms underlying skin immunity. The current manuscript concentrates explicitly on the communication pathways between MCs and ILC2s in the skin, highlighting their ability to regulate immune responses, inflammation, and tissue repair...
March 6, 2024: Cells