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https://www.readbyqxmd.com/read/29161440/novel-arch-fenestrated-stent-graft-for-acute-stanford-type-a-aortic-dissection-with-open-antegrade-implantation
#1
Qing Zhou, Yunxing Xue, Hailong Cao, Jun Pan, Qiang Wang, Fudong Fan, Dongjin Wang
OBJECTIVES: The best surgical strategy for acute Stanford Type A aortic dissection (aTAAD) involving the arch remains controversial. Here, we report on the satisfactory results following aTAAD repair using a novel arch fenestrated stent graft. METHODS: From December 2014 to December 2015, 42 aTAAD patients (27 male and 15 female) underwent ascending aorta replacement and fenestrated stent graft implantation. The fenestrated stent graft was implanted into the true lumen of the aortic arch and proximal descending aorta, with the fenestration opening located at the ostia of 3 head vessels in the arch...
November 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29161172/development-of-an-attachable-endoscopic-nerve-stimulator-for-intraoperative-neuromonitoring-during-endoscopic-or-robotic-thyroidectomy
#2
Eui-Suk Sung, Jin-Choon Lee, Seok Hyun Kim, Sung-Chan Shin, Da-Woon Jung, Byung-Joo Lee
We developed a simple attachable endoscopic nerve stimulator that can be connected to monopolar cauterization surgical instruments. This study on porcine models aimed to investigate the feasibility and efficacy of an attachable endoscopic nerve stimulator for intraoperative neuromonitoring (IONM) before application in humans. We evaluated the electromyography (EMG) amplitudes of 8 recurrent laryngeal nerves in 4 pigs with a conventional nerve probe and the attachable endoscopic nerve stimulator. The attachable endoscopic nerve stimulator was feasible and safe in all cases...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29160938/-knitting-through-the-mesh-novel-single-channel-troubleshooter-technique-for-dilation-assisted-transstricture-retrieval-of-a-migrated-gastroduodenal-stent
#3
Vincent Zimmer
Gastroduodenal stenting using self-expandable metallic stents (SEMSs) represents a viable endoscopic option for palliative treatment of gastric outlet obstruction (GOO), less invasive relative to surgical and/or endoscopic ultrasound-guided gastroenterostomy (EUS-GE). Nevertheless, high rates of stent dysfunction remain a significant Achilles' heel of the procedure. Endoscopic removal of a distally migrated gastroduodenal stent remains challenging with single-channel techniques, calling for individually tailored solutions vis-à-vis the inevitable upstream stricture...
November 21, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29159719/effect-of-a-real-time-electronic-dashboard-on-a-rapid-response-system
#4
Grant S Fletcher, Barry A Aaronson, Andrew A White, Reena Julka
A rapid response system (RRS) may have limited effectiveness when inpatient providers fail to recognize signs of early patient decompensation. We evaluated the impact of an electronic medical record (EMR)-based alerting dashboard on outcomes associated with RRS activation. We used a repeated treatment study in which the dashboard display was successively turned on and off each week for ten 2-week cycles over a 20-week period on the inpatient acute care wards of an academic medical center. The Rapid Response Team (RRT) dashboard displayed all hospital patients in a single view ranked by severity score, updated in real time...
November 20, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29158591/surgical-oncology-for-gliomas-the-state-of-the-art
#5
REVIEW
Nader Sanai, Mitchel S Berger
Surgical resection remains the mainstay of treatment for patients with glioma of any grade. Maximal resection of the tumour is central to achieving long-term disease control; however, the relationship between the extent of glioma resection and actual clinical benefit for the patient is predicated on the balance between cytoreduction and neurological morbidity. For the neurosurgical oncologist, the clinical rationale for undertaking increasingly extensive resections has gained traction. In parallel, novel surgical techniques and technologies have been developed that help improve patient outcomes...
November 21, 2017: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/29158017/left-atrial-appendage-occlusion-exclusion-procedural-image-guidance-with-transesophageal-echocardiography
#6
REVIEW
Alan F Vainrib, Serge C Harb, Wael Jaber, Ricardo J Benenstein, Anthony Aizer, Larry A Chinitz, Muhamed Saric
Atrial fibrillation is the most common arrhythmia worldwide and is a major risk factor for embolic stroke. In this article, the authors describe the crucial role of two- and three-dimensional transesophageal echocardiography in the pre- and postprocedural assessment and intraprocedural guidance of percutaneous left atrial appendage (LAA) occlusion procedures. Although recent advances have been made in the field of systemic anticoagulation with the novel oral anticoagulants, these medications come with a significant risk for bleeding and are contraindicated in many patients...
November 17, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29157525/transcatheter-tricuspid-valve-replacement
#7
REVIEW
Amar Krishnaswamy, Jose Navia, Samir R Kapadia
Tricuspid regurgitation (TR) is a common entity, most commonly functional in nature due to right-sided dysfunction in the setting of concomitant cardiac disease or pulmonary hypertension. Patients living with TR often experience numerous limitations as a result of right-sided heart failure symptoms, including functional decline, frequent hospitalizations, liver failure, and kidney failure. Furthermore, patients with significant TR demonstrate worse survival, although a cause-and-effect relationship has not been proven...
January 2018: Interventional cardiology clinics
https://www.readbyqxmd.com/read/29157035/a-new-approach-to-fertility-preserving-surgery-in-patients-with-placenta-accretaplacenta-accreta
#8
Sergey Barinov, Yuliya Tirskaya, Irina Medyannikova, Irina Shamina, Inna Shavkun
BACKGROUND: The aim of this study was to evaluate the efficacy of a novel combined surgical approach utilising: (1) two autonomous balloon Zhukovsky catheters (vaginal and uterine), (2) bilateral ligation of the descending uterine artery branches, (3) external supraplacental pleated sutures, and (4) either excision of a small area of placenta accreta or full metroplasty, for the management of uterine bleeding associated with placenta accreta of various severity. MATERIALS AND METHODS: The study included medical records of 92 pregnant women with placenta accreta undergoing caesarean section...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29156722/whole-exome-sequencing-reveals-novel-mutations-and-epigenetic-regulation-in-hypopharyngeal-carcinoma
#9
Ping Wu, Honglong Wu, Yaoyun Tang, Shi Luo, Xing Fang, Chubo Xie, Jian He, Suping Zhao, Xiaofeng Wang, Jiajia Xu, Xi Chen, Dongfang Li, Huanming Yang, Jian Wang
Hypopharyngeal cancer (HPC) frequently presents at an advanced stage, resulting in poor prognosis. Although combined surgical therapy and chemoradiotherapy have improved the survival for patients with HPC over the past 3 decades, the mortality rate in late-stage diagnosis of HPC is unsatisfactory. In this study, we performed whole-exome sequencing (WES) of 23 hypopharyngeal tumor and paired adjacent normal tissue to identify novel candidate driver genes associated with hypopharyngeal carcinoma. We identified several copy number variants (CNVs) and 15 somatic mutation genes that were associated with hypopharyngeal carcinoma...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29155782/partial-optic-nerve-transection-in-rats-a-model-established-with-a-new-operative-approach-to-assess-secondary-degeneration-of-retinal-ganglion-cells
#10
Fancheng Yan, Sailiang Guo, Yijie Chai, Lan Zhang, Kegao Liu, Qingjun Lu, Ningli Wang, Shuning Li
Previous studies have shown that the secondary degeneration of retinal ganglion cells (RGCs) occurs commonly in glaucoma. Partial optic nerve transection is considered a useful and reproducible model. Compared with other optic nerve injury models used commonly for assessing secondary degeneration, e.g. complete optic nerve transection and optic nerve crush models, the partial optic nerve transection model is superior as it distinguishes primary from secondary degeneration in situ. Therefore, it serves as an excellent tool for evaluating secondary degeneration...
October 15, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155624/functional-and-targeted-lymph-node-imaging-in-prostate-cancer-current-status-and-future-challenges
#11
Harriet C Thoeny, Sebastiano Barbieri, Johannes M Froehlich, Baris Turkbey, Peter L Choyke
Patients with prostate cancer who have regional lymph node (LN) metastases face an increased risk of death from disease and are therefore treated aggressively. Surgical LN dissection is the established method of staging regional nodes; however, this invasive technique carries substantial morbidities and a noninvasive imaging method is needed to reduce or eliminate the need for extended pelvic LN dissections (ePLND). Conventional computed tomography and magnetic resonance (MR) imaging have proven insensitive and nonspecific because both use nodal size criteria, which is notoriously inaccurate...
December 2017: Radiology
https://www.readbyqxmd.com/read/29155194/a-case-of-prenatally-diagnosed-wilms-tumor-managed-with-laparoscopic-nephrectomy
#12
Amir Toussi, Candace F Granberg, Patricio C Gargollo
We present a case of prenatally diagnosed Wilms' tumor, subsequent operative approach and management. The patient was referred to our institution with an abnormal prenatal renal ultrasound. CT scan after delivery showed a multifocal enhancing left renal mass. She underwent an uncomplicated left laparoscopic radical nephrectomy and retroperitoneal lymph node sampling using a novel hidden incision endoscopic surgery (HIdES) technique. Final pathology revealed favorable histology Stage II Wilms' Tumor. She received adjuvant chemotherapy with Vincristine and Dactinomycin based on the EE4A regimen...
November 16, 2017: Urology
https://www.readbyqxmd.com/read/29154228/practical-prognostic-score-for-predicting-the-extent-of-resection-and-neurological-outcome-of-gliomas-in-the-sensorimotor-area
#13
Giannantonio Spena, Federico D'Agata, Pier Paolo Panciani, Luciano Buttolo, Michela Buglione di Monale Bastia, Marco Maria Fontanella
OBJECTIVE: In this prospective study, we assessed the utility of a novel prognostic score (PS) in guiding the surgical strategy of patients with sensorimotor area gliomas. PATIENTS AND METHODS: Form December 2012 to April 2016, we collected data from patients diagnosed with brain gliomas in the sensorimotor area. All the patients had intraoperatively confirmed contiguity or continuity with sensorimotor cortical and subcortical structures. Several clinical and radiological factors were analyzed to generate a PS for each patient (range 1-8)...
November 16, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29153940/tumor-derived-cytokines-impair-myogenesis-and-alter-the-skeletal-muscle-immune-microenvironment
#14
Kelly A Hogan, Dong Seong Cho, Paige C Arneson, Adrienne Samani, Patrick Palines, Yanan Yang, Jason D Doles
Muscle wasting is a decline in skeletal muscle mass and function that is associated with aging, obesity, and a spectrum of pathologies including cancer. Cancer-associated wasting not only reduces quality of life, but also directly impacts cancer mortality, chemotherapeutic efficacy, and surgical outcomes. There is an incomplete understanding of the role of tumor-derived factors in muscle wasting and sparse knowledge of how these factors impact in vivo muscle regeneration. Here, we identify several cytokines/chemokines that negatively impact in vitro myogenic differentiation...
November 16, 2017: Cytokine
https://www.readbyqxmd.com/read/29153451/a-novel-minimally-invasive-surgery-combined-with-early-exercise-therapy-promoting-tendon-regeneration-in-the-treatment-of-spontaneous-achilles-tendon-rupture
#15
Amuding Aisaiding, Jianping Wang, Rouziwanguli Maimaiti, Ayidaer Jialihasia, Rakimbaiev Aibek, Bayixiati Qianman, Nuerai Shawutali, Aynaz Badelhan, Wulan Bahetiya, Aliya Kubai, Mailamuguli Kelamu, Yeermike Nuerdoula, Elihaer Makemutibieke, Yerzat Bakyt, Jianati Wuerliebieke, Jiasharete Jielile
OBJECTIVE: Acute closed spontaneous Achilles tendon rupture often occurs in elderly individuals and is usually accompanied with many complications. Conventional surgical approaches to remove the tendon lesions and enthesophytes are highly traumatic and cause complications. In this study, a previously established minimally invasive surgical approach was modified and combined with a Kazakh exercise therapy to reduce trauma, improve wound healing, and promote tendon regeneration in the management of acute closed spontaneous Achilles tendon rupture...
October 31, 2017: Injury
https://www.readbyqxmd.com/read/29152792/novel-technique-using-a-non-tip-and-short-wire-papillotome-for-biliary-cannulation-of-intradiverticular-papilla-in-patients-with-roux-en-y-anastomosis
#16
Maya Suguro, Kenjiro Yamamoto, Takao Itoi
Balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (BE-ERCP) has enabled the endoscopic treatment of pancreatobiliary disease in patients with a surgically altered gastrointestinal anatomy.(1-3) However, even though the endoscope can reach the papilla, successful cannulation of the common bile duct may be difficult in the papilla located within a diverticulum because of an insufficient distance from the papilla in the tangential direction. Therefore endoscopic ultrasound-guided biliary drainages have been reported as useful and safety methods...
November 20, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29152469/eyebrow-incision-for-surgical-evacuation-of-a-lobar-intracerebral-hematoma-with-a-novel-endoport-system
#17
Dale Ding, Colin J Przybylowski, Robert M Starke, R Webster Crowley, Kenneth C Liu
Large lobar intracerebral hemorrhages (ICHs) can cause rapid neurological deterioration, and affected patients have low rates of survival and functional independence. Currently, the role of surgical intervention in the management patients with lobar ICHs is controversial. Minimally invasive technologies have been developed which may potentially decrease the operative morbidity of ICH surgery. The aim of this case report is to describe the technical aspects of the use of a novel minimally invasive endoport system, the BrainPath (NICO, Indianapolis, IN, USA), through an eyebrow incision for evacuation of a large lobar hematoma...
June 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/29152454/recent-advances-in-retinal-stem-cell-therapy
#18
Sujoy Bhattacharya, Rajashekhar Gangaraju, Edward Chaum
Purpose of review: Progress in stem cell research for blinding diseases over the past decade is now being applied to patients with retinal degenerative diseases and soon perhaps, glaucoma. However, the field still has much to learn about the conversion of stem cells into various retinal cell types, and the potential delivery methods that will be required to optimize the clinical efficacy of stem cells delivered into the eye. Recent findings: Recent groundbreaking human clinical trials have demonstrated both the opportunities and current limitations of stem cell transplantation for retinal diseases...
September 2017: Current Molecular Biology Reports
https://www.readbyqxmd.com/read/29151974/preoperative-albumin-bilirubin-score-for-postoperative-solitary-hepatocellular-carcinoma-within-the-milan-criteria-and-child-pugh-a-cirrhosis
#19
Zhao-Ru Dong, Jie Zou, Dong Sun, Guo-Ming Shi, Ai-Wu Ke, Jia-Bin Cai, Hui-Chuan Sun, Shuang-Jian Qiu, Tao Li, Jian Zhou, Xu-Ting Zhi, Jia Fan
Surgical resection remains the initial treatment of choice for the majority of early stage hepatocellular carcinoma (HCC) patients. Although the factors that influence the prognosis of postoperative HCC patients have been well elucidated, there are a limited number of simple, objective, and distinct methods for estimating survival for postoperative patients with solitary HCC within the Milan criteria and Child-Pugh (C-P) A cirrhosis. The Albumin-Bilirubin (ALBI) score is a new evidence-based approach to assess liver function...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/29151912/duodenal-angiomyolipoma-with-multiple-systemic-vascular-malformations-and-aneurysms-a-case-report-and-literature-review
#20
Yiqiu Wang, Xiuli Zhang, Peng Liu, Guan Jiang, Wenlou Liu
Angiomyolipomas (AMLs) are barely benign mesenchymal tumors that usually occur in the kidneys and may be associated with tuberous sclerosis complex (TSC). Extrarenal AMLs are markedly rare and infrequently observed in the duodenum. In the present case report, a 22-year-old female patient with duodenal AMLs presenting multiple systemic vascular malformations and aneurysms is described. The patient had a medical history of aneurysm rupture of the right subclavian artery and no other manifestation of TSC. Surgical intervention was performed...
December 2017: Oncology Letters
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