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https://www.readbyqxmd.com/read/28215927/will-drug-companies-price-transparency-efforts-fall-short
#1
Bryant Furlow
No abstract text is available yet for this article.
February 16, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28182258/improving-access-to-high-cost-cancer-drugs-in-latin-america-much-to-be-done
#2
REVIEW
Rossana Ruiz, Kathrin Strasser-Weippl, Diego Touya, Carmen Herrero Vincent, Abraham Hernandez-Blanquisett, Jessica St Louis, Alexandra Bukowski, Paul E Goss
Lack of access to high-cost medications is a complex issue at the intersection of economics, medicine, politics, and ethics, and it poses a significant threat to global health care. The problem is even more significant in low- and middle-income countries, such as those in Latin America, where governments and individuals struggle to pay for products that are priced at several times the level of their per capita gross domestic product. In this review, we examine the determinants for increasing drug costs and how Latin American countries face this burgeoning crisis...
February 9, 2017: Cancer
https://www.readbyqxmd.com/read/28168538/price-transparency-in-primary-care-can-patients-learn-about-costs-when-scheduling-an-appointment
#3
Brendan Saloner, Lisa Clemans Cope, Katherine Hempstead, Karin V Rhodes, Daniel Polsky, Genevieve M Kenney
BACKGROUND: Cost-sharing in health insurance plans creates incentives for patients to shop for lower prices, but it is unknown what price information patients can obtain when scheduling office visits. OBJECTIVE: To determine whether new patients can obtain price information for a primary care visit and identify variation across insurance types, offices, and geographic areas. DESIGN: Simulated patient methodology in which trained interviewers posed as non-elderly adults seeking new patient primary care appointments...
February 6, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28152718/ontario-s-approach-to-tackling-drug-funding-sustainability
#4
Scott Gavura, Robin McLeod, Virginia McLaughlin, Craig Earle, Jessica Arias, Michelle Rey, Hasina Jamal
: 38 Background: One of the challenges facing Ontario relates to managing the rising costs of cancer drug treatments. The annual growth rate of cancer drug spending has increased by 10-20% since 2010, exceeding other therapeutic categories and is expected to continue to grow significantly faster than expenditures in other areas. Paradoxically, the price of a drug seems to have little relation to its demonstrated efficacy ( http://www.asco.org/practice-research/cancer-care-america-2015/focus-cost )...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28144830/cost-effective-personalized-3d-printed-liver-model-for-preoperative-planning-before-laparoscopic-liver-hemihepatectomy-for-colorectal-cancer-metastases
#5
Jan Sylwester Witowski, Michał Pędziwiatr, Piotr Major, Andrzej Budzyński
PURPOSE: Three-dimensional (3D) printing for preoperative planning has been intensively developed in the recent years. However, the implementation of these solutions in hospitals is still difficult due to high costs, extremely expensive industrial-grade printers, and software that is difficult to obtain and learn along with a lack of a defined process. This paper presents a cost-effective technique of preparing 3D-printed liver models that preserves the shape and all of the structures, including the vessels and the tumor, which in the present case is colorectal liver metastasis...
January 31, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28121579/a-health-care-consumer-gender-gap
#6
Jan Greene
Women are the unpaid case workers of the American health care system and they don't trust insurers mainly because insurers aren't doing enough to earn that trust. Among other things, price transparency and better cooperation between payers and providers might help address this situation.
August 2016: Managed Care
https://www.readbyqxmd.com/read/28117276/glutaminolysis-is-essential-for-energy-production-and-ion-transport-in-human-corneal-endothelium
#7
Wenlin Zhang, Hongde Li, Diego G Ogando, Shimin Li, Matthew Feng, Francis W Price, Jason M Tennessen, Joseph A Bonanno
Corneal endothelium (CE) is among the most metabolically active tissues in the body. This elevated metabolic rate helps the CE maintain corneal transparency by its ion and fluid transport properties, which when disrupted, leads to visual impairment. Here we demonstrate that glutamine catabolism (glutaminolysis) through TCA cycle generates a large fraction of the ATP needed to maintain CE function, and this glutaminolysis is severely disrupted in cells deficient in NH3:H(+) cotransporter Solute Carrier Family 4 Member 11 (SLC4A11)...
January 13, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28063134/how-can-pricing-and-reimbursement-policies-improve-affordable-access-to-medicines-lessons-learned-from-european-countries
#8
REVIEW
Sabine Vogler, Valérie Paris, Alessandra Ferrario, Veronika J Wirtz, Kees de Joncheere, Peter Schneider, Hanne Bak Pedersen, Guillaume Dedet, Zaheer-Ud-Din Babar
This article discusses pharmaceutical pricing and reimbursement policies in European countries with regard to their ability to ensure affordable access to medicines. A frequently applied pricing policy is external price referencing. While it provides some benchmark for policy-makers and has been shown to be able to generate savings, it may also contribute to delay in product launch in countries where medicine prices are low. Value-based pricing has been proposed as a policy that promotes access while rewarding useful innovation; however, implementing it has proven quite challenging...
January 6, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28050974/modifying-optical-properties-of-reduced-graphene-oxide-with-controlled-ozone-and-thermal-treatment-in-aqueous-suspensions
#9
Md Tanvir Hasan, Brian J Senger, Price Mulford, Conor Ryan, Hung Doan, Zygmunt Gryczynski, Anton V Naumov
Graphene possesses a number of advantageous properties, however, does not exhibit optical emission, which limits its use in optoelectronics. Unlike graphene, its functional derivative, graphene oxide (GO) exhibits fluorescence emission throughout the visible. Here, we focus on controlled methods for tuning the optical properties of GO. We introduce ozone treatment of reduced graphene oxide (RGO) in order to controllably transform it from non-emissive graphene-like material into GO with a specific fluorescence emission response...
January 4, 2017: Nanotechnology
https://www.readbyqxmd.com/read/27993208/the-price-of-surgery-markup-of-operative-procedures-in-the-united-states
#10
Faiz Gani, Martin A Makary, Timothy M Pawlik
BACKGROUND: Despite cost containment efforts, the price for surgery is not subject to any regulations. We sought to characterize and compare variability in pricing for commonly performed major surgical procedures across the United States. METHODS: Medicare claims corresponding to eight major surgical procedures (aortic aneurysm repair, aortic valvuloplasty, carotid endartectomy, coronary artery bypass grafting, esophagectomy, pancreatectomy, liver resection, and colectomy) were identified using the Medicare Provider Utilization and Payment Data Physician and Other Supplier Public Use File for 2013...
February 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/27920322/patients-who-choose-primary-care-physicians-based-on-low-office-visit-price-can-realize-broader-savings
#11
Ateev Mehrotra, Peter J Huckfeldt, Amelia M Haviland, Laura Gascue, Neeraj Sood
Price transparency initiatives encourage patients to save money by choosing physicians with a relatively low price per office visit. Given that the price of such visits represents a small fraction of total spending, the extent of the savings from choosing such physicians has not been clear. Using a national sample of commercial claims data, we compared the care received by patients of high- and low-price primary care physicians. The median price for an established patient's office visit was $60 among low-price physicians and $86 among high-price physicians (price was calculated as reimbursement plus out-of-pocket spending)...
December 1, 2016: Health Affairs
https://www.readbyqxmd.com/read/27913941/the-enigma-of-value-in-search-of-affordable-and-accessible-health-care
#12
EDITORIAL
Thomas D Szucs, Martina Weiss, Guido Klaus
In times of shrinking resources and pharmaceutical breakthrough situations, our value-assessing systems are stretched to their very limits. Assessing value is highly complex. Current value-assessment systems risk neglecting important factors, such as therapy duration, budget impact, or the importance of combination therapies. Especially when dealing with breakthrough therapies within high-prevalence indications, these factors play an important role in health care spending. When it comes to assessing value in Switzerland, the system is innovation and access-friendly; the price level of pharmaceutical products, however, is relatively high in comparison to neighboring countries...
December 2, 2016: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/27913910/a-randomized-trial-of-displaying-paid-price-information-on-imaging-study-and-procedure-ordering-rates
#13
Alyna T Chien, Lisa Soleymani Lehmann, Laura A Hatfield, Kate E Koplan, Carter R Petty, Anna D Sinaiko, Meredith B Rosenthal, Thomas D Sequist
BACKGROUND: Prior studies have demonstrated how price transparency lowers the test-ordering rates of trainees in hospitals, and physician-targeted price transparency efforts have been viewed as a promising cost-controlling strategy. OBJECTIVE: To examine the effect of displaying paid-price information on test-ordering rates for common imaging studies and procedures within an accountable care organization (ACO). DESIGN: Block randomized controlled trial for 1 year...
December 2, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27877899/carbon-nanotube-based-transparent-conductive-films-progress-challenges-and-perspectives
#14
Ying Zhou, Reiko Azumi
Developments in the manufacturing technology of low-cost, high-quality carbon nanotubes (CNTs) are leading to increased industrial applications for this remarkable material. One of the most promising applications, CNT based transparent conductive films (TCFs), are an alternative technology in future electronics to replace traditional TCFs, which use indium tin oxide. Despite significant price competition among various TCFs, CNT-based TCFs have good potential for use in emerging flexible, stretchable and wearable optoelectronics...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27834308/a-platform-for-colorful-solar-cells-with-enhanced-absorption
#15
Navneet Dhindsa, Jaspreet Walia, Simarjeet Singh Saini
We demonstrate submicron thick platform integrating amorphous silicon nanowires and thin-films achieving vivid colors in transmission and reflection. The platform nearly doubles the absorption efficiency compared to the starting thin-film without much compromising with color diverseness. The structural colors can be changed over a wide range by changing the diameters of the nanowires while still keeping the absorption efficiency higher than starting thin-film. The optical response of the platform is conceptually understood for different diameters combined with different thin-film thicknesses indicating the presence of leaky waveguide modes and coupled cavity modes...
December 9, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27815064/inhaled-corticosteroid-adherence-patterns-in-a-longitudinal-asthma-cohort
#16
Patrick C Souverein, Ellen S Koster, Gene Colice, Eric van Ganse, Alison Chisholm, David Price, Alexandra L Dima
BACKGROUND: Electronic prescribing records can enable exploration of medication adherence, but analysis decisions may influence estimates and require alignment to new consensus-based definitions. OBJECTIVE: To compare different computations of inhaled corticosteroid (ICS) implementation in a primary care asthma population initiating ICS therapy when assessed within episodes of persistent use, and examine longitudinal variation in implementation. METHODS: A historical cohort study was conducted on UK's Optimum Patient Care Research Database...
November 1, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27806412/-biosimilars-in-gastroenterology-how-much-uncertainly-is-ethically-acceptable
#17
N Knoepffler
Biosimilars use raises uncertainties with regards to efficacy despite potentially significant cost reductions. This requires a classical harm-benefit analysis. Important stakeholders include physicians and patients, companies producing biologica (drugs containing biotechnology-derived proteins as active substance), and companies producing biosimilars, as well as health insurance companies and politicians. They all have their distinct interests. In a rule-setting process, transparency is needed to protect the trust between patients and physicians...
November 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27729442/the-new-politics-of-us-health-care-prices-institutional-reconfiguration-and-the-emergence-of-all-payer-claims-databases
#18
Philip Rocco, Andrew S Kelly, Daniel Béland, Michael Kinane
Prices are a significant driver of health care cost in the United States. Existing research on the politics of health system reform has emphasized the limited nature of policy entrepreneurs' efforts at solving the problem of rising prices through direct regulation at the state level. Yet this literature fails to account for how change agents in the states gradually reconfigured the politics of prices, forging new, transparency-based policy instruments called all-payer claims databases (APCDs), which are designed to empower consumers, purchasers, and states to make informed market and policy choices...
October 11, 2016: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/27707687/a-checklist-for-the-conduct-reporting-and-appraisal-of-microcosting-studies-in-health-care-protocol-development
#19
Jennifer Prah Ruger, Marian Reiff
BACKGROUND: Microcosting is a cost estimation method that requires the collection of detailed data on resources utilized, and the unit costs of those resources in order to identify actual resource use and economic costs. Microcosting findings reflect the true costs to health care systems and to society, and are able to provide transparent and consistent estimates. Many economic evaluations in health and medicine use charges, prices, or payments as a proxy for cost. However, using charges, prices, or payments rather than the true costs of resources can result in inaccurate estimates...
October 5, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27636366/-benefit-assessment-and-price-negotiation-under-amnog-calculable-process-or-unfair-poker-game
#20
D Radic, S Haugk, M Radic
Ever since the introduction of the Market Restructuring Act, the evaluation and price negotiations of drugs have been controversial. While the Federal Joint Committee considers that the process is transparent and in accordance with clear evidence-based criteria, representatives of pharmaceutical companies are particularly critical of the fact that the central association of statutory health insurance is involved in both the determination of added therapeutic benefit of drugs as well as in the subsequent price negotiation...
September 16, 2016: Das Gesundheitswesen
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