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https://www.readbyqxmd.com/read/27913713/the-allocation-of-sexually-transgressive-juveniles-to-intensive-specialized-treatment-an-assessment-of-the-application-of-rnr-principles
#1
Ellis Ter Beek, Rachel E A van der Rijken, Chris H Z Kuiper, Jan Hendriks, Geert Jan J M Stams
The aim of this study was to compare results of and develop guidelines for mandatory allocation of sexually transgressive juveniles to Multisystemic Therapy - Problem Sexual Behavior (MST-PSB), Secure Youth Care (SYC), or Forensic Youth Care (FYC), based on the risk-need-responsivity model. Results of current allocation showed a population with relatively less treatment needs to receive community-based MST-PSB, compared with populations receiving residential SYC and FYC. Furthermore, estimated recidivism risk levels did not always support the need for risk reduction by the imposition of limitation of freedom of movement and maximum supervision, provided by all three treatment modalities...
December 1, 2016: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/27907114/rates-and-predictors-of-non-adherence-to-antiretroviral-therapy-among-hiv-positive-individuals-in-kenya-results-from-the-second-kenya-aids-indicator-survey-2012
#2
Irene N Mukui, Lucy Ng'ang'a, John Williamson, Joyce N Wamicwe, Shobha Vakil, Abraham Katana, Andrea A Kim
INTRODUCTION: Understanding the levels and associated factors of non-adherence to antiretroviral therapy (ART) is crucial in designing interventions to improve adherence and health outcomes of ART. We assessed non-adherence to ART among HIV-infected persons reporting ART use in a nationally representative survey in Kenya. METHODS: The Kenya AIDS Indicator Survey 2012 was a population-based, household survey of persons aged 18 months-64 years conducted in 2012-2013...
2016: PloS One
https://www.readbyqxmd.com/read/27906881/stem-cells-and-clinical-practice-new-advances-and-challenges-at-the-time-of-emerging-problems-with-induced-pluripotent-stem-cell-therapies
#3
Mariusz Z Ratajczak, Kamila Bujko, Wojciech Wojakowski
Humans, like other species that reproduce sexually, originate from a fertilized oocyte (zygote), which is a totipotent stem cell giving rise to an adult organism. During the process of embryogenesis, stem cells at different levels of the developmental hierarchy establish all 3 germ layers and give rise to tissue‑committed stem cells, which are responsible for rejuvenation of a given tissue or organ. The robustness of the stem cell compartment is one of the major factors that directly impact life quality as well as lifespan...
November 10, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27904805/hypothesis-on-serenoa-repens-bartram-small-extract-inhibition-of-prostatic-5%C3%AE-reductase-through-an-in-silico-approach-on-5%C3%AE-reductase-x-ray-structure
#4
Paolo Governa, Daniela Giachetti, Marco Biagi, Fabrizio Manetti, Luca De Vico
Benign prostatic hyperplasia is a common disease in men aged over 50 years old, with an incidence increasing to more than 80% over the age of 70, that is increasingly going to attract pharmaceutical interest. Within conventional therapies, such as α-adrenoreceptor antagonists and 5α-reductase inhibitor, there is a large requirement for treatments with less adverse events on, e.g., blood pressure and sexual function: phytotherapy may be the right way to fill this need. Serenoa repens standardized extract has been widely studied and its ability to reduce lower urinary tract symptoms related to benign prostatic hyperplasia is comprehensively described in literature...
2016: PeerJ
https://www.readbyqxmd.com/read/27903951/a-management-algorithm-for-retained-rectal-foreign-bodies
#5
Shamir O Cawich, Dexter A Thomas, Fawwaz Mohammed, Nahmorah J Bobb, Dorothy Williams, Vijay Naraynsingh
Few authors have proposed therapeutic protocols to manage retained rectal foreign bodies (RFBs). All patients with retained RFBs in hospitals across Trinidad and Tobago over 5 years were identified. Hospital records were retrieved and manually reviewed to extract the following data: demographics, history, foreign body retrieved, clinical signs at presentation, management strategy, duration of hospitalization, and morbidity and mortality. There were 10 patients with RFBs over the study period. The annual incidence of this phenomenon was 0...
November 29, 2016: American Journal of Men's Health
https://www.readbyqxmd.com/read/27901106/the-role-of-pim1-pim2-kinases-in-tumors-of-the-male-reproductive-system
#6
Manuel Pedro Jiménez-García, Antonio Lucena-Cacace, María José Robles-Frías, Maja Narlik-Grassow, Carmen Blanco-Aparicio, Amancio Carnero
The PIM family of serine/threonine kinases has three highly conserved isoforms (PIM1, PIM2 and PIM3). PIM proteins are regulated through transcription and stability by JAK/STAT pathways and are overexpressed in hematological malignancies and solid tumors. The PIM kinases possess weak oncogenic abilities, but enhance other genes or chemical carcinogens to induce tumors. We generated conditional transgenic mice that overexpress PIM1 or PIM2 in male reproductive organs and analyzed their contribution to tumorigenesis...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27900931/hiv-positive-migrants-encounters-with-the-swedish-health-care-system
#7
Manijeh Mehdiyar, Rune Andersson, Katarina Hjelm, Lene Povlsen
BACKGROUND: There is limited knowledge about human immunodeficiency virus (HIV)-positive migrants and their experiences in the Swedish health care system. It is necessary to increase our knowledge in this field to improve the quality of care and social support for this vulnerable group of patients. OBJECTIVE: The aim of this study was to describe the experiences of HIV-positive migrants and their encounters with the health care system in Sweden. DESIGN: This is a Grounded Theory study based on qualitative interviews with 14 HIV-positive migrants living in Sweden, aged 29-55 years...
2016: Global Health Action
https://www.readbyqxmd.com/read/27898651/prevalence-and-correlates-of-vaginal-estrogenization-in-postmenopausal-women-in-the-united-states
#8
Stacy Tessler Lindau, Annie Dude, Natalia Gavrilova, Joscelyn N Hoffmann, L Philip Schumm, Martha K McClintock
OBJECTIVE: This work aims to establish current population-based vaginal estrogenization norms for postmenopausal US women. METHODS: Using a US national probability sample of 868 postmenopausal women ages 57 to 85 years (mean age 67.6 ± 0.3 y, 21.6 ± 0.5 y since menopause), we calculated the epithelial maturation value (MV) generated from self-collected vaginal specimens and compared findings with historical clinical data. Linear and logistic regressions were used to describe the relationship between vaginal estrogenization and sociodemographic, physical, gynecologic, and sexual characteristics...
November 28, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27898574/factors-associated-with-primary-care-physician-knowledge-of-the-recommended-regimen-for-treating-gonorrhea
#9
Marta Bornstein, Faruque Ahmed, Roxanne Barrow, Jami Fraze Risley, Sheena Simmons, Kimberly A Workowski
BACKGROUND: The recommended regimen for treating uncomplicated gonorrhea has changed over time, due to the emergence of antimicrobial resistance. We assessed physician knowledge of the recommendation for treating uncomplicated urogenital gonorrhea in adolescents and adults using ceftriaxone and azithromycin dual therapy. METHODS: We analyzed DocStyles 2015 survey data from 1357 primary care physicians practicing for at least 3 years who provided screening, diagnosis, or treatment for sexually transmitted diseases to one or more patients in an average month...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898566/antiretroviral-therapy-initiation-is-not-associated-with-risky-sexual-behavior-among-heterosexual-human-immunodeficiency-virus-infected-persons-in-serodiscordant-partnerships
#10
Andrew Mujugira, Connie Celum, Kenneth Ngure, Katherine K Thomas, Elly Katabira, Jared M Baeten
BACKGROUND: Few prospective studies have assessed whether antiretroviral therapy (ART) use is associated with changes in sexual risk behavior of human immunodeficiency virus (HIV)-infected persons in known HIV-serodiscordant partnerships. METHODS: We conducted a longitudinal analysis of HIV-infected persons with known uninfected partners enrolled in the Partners Pre-Exposure Prophylaxis Study in Kenya and Uganda. Antiretroviral therapy use and self-reported sexual behavior were ascertained every 3 months...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27897021/-sexual-morbidity-of-cervical-carcinoma-survivors
#11
P Herboltová, A Roztočil
OBJECTIVE: We are aware that patients with cervical carcinoma in the Czech Republic are poorly informed about sexual aspects of their therapy and there is also very poor attention paid to this problem in the Czech literature. Therefore we decided to evaluate the situation in a group of patients from our department using our own questionaire. We compared our results with contemporary world literature. DESIGN: Questionnaire survey, comparison with world literature...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27896258/secondary-abdominal-pregnancy-in-human-immunodeficiency-virus-positive-woman
#12
Myoung Chan Kim, Hudson Manyanga, Flora Lwakatare
We report on an abdominal pregnancy in human immunodeficiency virus-positive mother, currently on antiretroviral therapy, which was discovered incidentally while training the obstetric ultrasound capacity building program. Although abdominal pregnancy is a rare form of ectopic pregnancy, it may be more common in women with HIV infection because they tend to have a higher rate of sexually transmitted diseases than the general population. The positive diagnosis of abdominal pregnancy is difficult to establish and is usually missed during prenatal assessment particularly in settings that lack routine ultrasound examination as is the case in most developing countries...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27892795/using-emotionally-focused-therapy-to-treat-sexual-desire-discrepancy-in-couples
#13
Abby Girard, Scott R Woolley
Couples in committed relationships encounter a multitude of issues. According to Metz and McCarthy (2010), when couples report high sexual satisfaction, it accounts for 15-20% of their overall relationship satisfaction. However, when couples report low sexual satisfaction, it contributes 50-70% of their overall satisfaction with their partner. Issues of sexual desire, currently referred to as sexual desire discrepancy, are among the most difficult to treat. Although there are many factors contributing to the issue of sexual desire discrepancy, current literature highlights the importance of emotional intimacy as an outcome and predictor of increased sexual desire...
November 28, 2016: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/27890947/profile-of-pneumocystis-infection-in-a-tertiary-care-institute-in-north-india
#14
Ravinder Kaur, Pragyan Swagatika Panda, Richa Dewan
CONTEXT: Pneumocystis jirovecii pneumonia (PcP) is still remains a common opportunistic disease in human immunodeficiency virus (HIV) infected individuals. Study on PcP in developing countries are scarce. AIMS: To study the occurrence of P. jirovecii infection in clinically suspected individuals in a tertiary care institute. SETTINGS AND DESIGN: Retrospective study conducted in a tertiary care hospital. MATERIALS AND METHODS: Two years data regarding respiratory sample analysis, HIV status, and cluster of differentiation 4 (CD4) cell count of clinically suspected pneumocystis infection patients with known/unknown HIV status were analyzed...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27890426/patient-reported-quality-of-life-after-stereotactic-body-radiation-therapy-versus-moderate-hypofractionation-for-clinically-localized-prostate-cancer
#15
Skyler Bryce Johnson, Pamela R Soulos, Timothy D Shafman, Constantine A Mantz, Arie P Dosoretz, Rudi Ross, Steven E Finkelstein, Sean P Collins, Simeng Suy, Jeffrey V Brower, Mark A Ritter, Christopher R King, Patrick A Kupelian, Eric M Horwitz, Alan Pollack, Matthew C Abramowitz, Mark A Hallman, Sergio Faria, Cary P Gross, James B Yu
BACKGROUND AND PURPOSE: Evaluate changes in bowel, urinary and sexual patient-reported quality of life following treatment with moderately hypofractionated radiotherapy (<5Gray/fraction) or stereotactic body radiation therapy (SBRT;5-10Gray/fraction) for prostate cancer. MATERIALS AND METHODS: In a pooled multi-institutional analysis of men treated with moderate hypofractionation or SBRT, we compared minimally detectable difference in bowel, urinary and sexual quality of life at 1 and 2years using chi-squared analysis and logistic regression...
November 24, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27887941/functional-outcomes-and-quality-of-life-after-radical-prostatectomy-only-versus-a-combination-of-prostatectomy-with-radiation-and-hormonal-therapy
#16
Meike Adam, Pierre Tennstedt, Dominik Lanwehr, Derya Tilki, Thomas Steuber, Burkhard Beyer, Imke Thederan, Hans Heinzer, Alexander Haese, Georg Salomon, Lars Budäus, Uwe Michl, Dirk Pehrke, Pär Stattin, Jürgen Bernard, Bernd Klaus, Raisa S Pompe, Cordula Petersen, Hartwig Huland, Markus Graefen, Rudolf Schwarz, Wolfgang Huber, Stacy Loeb, Thorsten Schlomm
BACKGROUND: While the optimal use and timing of secondary therapy after radical prostatectomy (RP) remain controversial, there are limited data on patient-reported outcomes following multimodal therapy. OBJECTIVE: To assess the impact of additional radiation therapy (RT) and/or androgen deprivation therapy (ADT) on urinary continence, potency, and quality of life (QoL) after RP. DESIGN, SETTING, AND PARTICIPANTS: Among 13150 men who underwent RP from 1992 to 2013, 905 received RP + RT, 407 RP + ADT and 688 RP + RT + ADT...
November 22, 2016: European Urology
https://www.readbyqxmd.com/read/27887581/design-of-a-randomized-controlled-trial-of-internet-based-cognitive-behavioral-therapy-for-treatment-induced-menopausal-symptoms-in-breast-cancer-survivors
#17
Vera Atema, Marieke van Leeuwen, Hester S A Oldenburg, Valesca Retèl, Marc van Beurden, Myra S Hunter, Neil K Aaronson
BACKGROUND: Menopausal symptoms are common and may be particularly severe in younger women who undergo treatment-induced menopause. Medications to reduce menopausal symptoms are either contra-indicated or have bothersome side effects. Previous studies have demonstrated that face-to-face cognitive behavioral therapy (CBT) is effective in alleviating menopausal symptoms in women with breast cancer. However, compliance with face-to-face CBT programs can be problematic. A promising approach is to use the Internet to make this form of CBT more accessible and feasible for patients...
November 25, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27882759/-management-of-care-of-hiv-positive-pregnant-women-in-the-period-1996-2014
#18
M Mojhová, I Mikysková, M Halaška, M Staňková, H Rozsypal, J Šrámek, J Záhumenský, M Malý
OBJECTIVE: The evaluation of multidisplinary care about HIV positive pregnant women in the Czech Republic. DESIGN: Review. SETTINGS: Gynekologicko-porodnická klinika 1. LF UK a Nemocnice na Bulovce, Praha. METHODS: The vertical transmission of HIV infection from mother to fetus occurs most often during birth, still 1-2% of HIV-positive pregnant women will transfer the virus transplacenta. Due to careful screening for HIV during pregnancy, counselling, combination antiretroviral (cART) therapy, childbirth planning and its performance by C-section there appears a significant decrease of the virus transmission to the fetus, its occurrence is around 2%...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27881887/changes-in-sexuality-body-image-and-health-related-quality-of-life-in-patients-treated-for-hematologic-malignancies-a-longitudinal-study
#19
Cecilia Olsson, Ann-Kristin Sandin-Bojö, Kaisa Bjuresäter, Maria Larsson
Longitudinal studies exploring sexuality, body image and health-related quality of life (HRQoL) are lacking in patients treated with chemo- or chemoimmuno-therapy for hematologic malignancies. The aim was to describe and explore changes in sexuality, body image and HRQoL in patients treated for hematologic malignancies, from baseline until 6 months after treatment. Twenty patients above 45 years (median age 62) treated for DLBCL, CLL or AML participated. Data were collected at baseline, 1- and 6-months after treatment by means of three instruments: SAQ-S, BIS and EORTC QLQ-C30...
2016: Sexuality and Disability
https://www.readbyqxmd.com/read/27881285/conventionally-fractionationed-volumetric-arc-therapy-versus-hypofractionated-stereotactic-body-radiotherapy-quality-of-life-side-effects-and-prostate-specific-antigen-kinetics-in-localized-prostate-cancer
#20
Makbule Tambas, Fulya Agaoglu, Ayca Iribas, Murat Guveli, Yavuz Dizdar, Murat Okutan, Dilek Sahin, Nuri Tenekeci, Emin Darendeliler
OBJECTIVES: To compare conventionally fractionationed volumetric arc therapy (VMAT) and hypofractionated stereotactic body radiotherapy (SBRT) modalities in terms of prostate-specific antigen (PSA) kinetics, toxicity, and quality of life (QOL) in patients with localized prostate cancer. METHODS: Patients received radical radiotherapy as either 33.5 Gy/5 fr for SBRT or 75.6 Gy/35 fr for VMAT. International Prostate Symptom Score (IPSS) and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Prostate Cancer Module (QLQ-PR25) forms were used to assess QOL...
September 2016: Value in Health Regional Issues
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