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Children Vaccination

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https://www.readbyqxmd.com/read/28811050/vaccine-decision-making-begins-in-pregnancy-correlation-between-vaccine-concerns-intentions-and-maternal-vaccination-with-subsequent-childhood-vaccine-uptake
#1
M H Danchin, J Costa-Pinto, K Atwell, H Willaby, K Wiley, M Hoq, J Leask, K P Perrett, Jacinta O'Keefe, M L Giles, H Marshall
INTRODUCTION: Maternal and childhood vaccine decision-making begins prenatally. Amongst pregnant Australian women we aimed to ascertain vaccine information received, maternal immunisation uptake and attitudes and concerns regarding childhood vaccination. We also aimed to determine any correlation between a) intentions and concerns regarding childhood vaccination, (b) concerns about pregnancy vaccination, (c) socioeconomic status (SES) and (d) uptake of influenza and pertussis vaccines during pregnancy and routine vaccines during childhood...
August 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28810833/population-effectiveness-of-the-pentavalent-and-monovalent-rotavirus-vaccines-a-systematic-review-and-meta-analysis-of-observational-studies
#2
Daniel Hungerford, Katie Smith, Angela Tucker, Miren Iturriza-Gómara, Roberto Vivancos, Catherine McLeonard, Nigel A Cunliffe, Neil French
BACKGROUND: Rotavirus was the leading cause of acute gastroenteritis (AGE) in infants and young children prior to the introduction of routine vaccination. Since 2006 there have been two licensed vaccines available; with successful clinical trials leading the World Health Organization to recommend rotavirus vaccination for all children worldwide. In order to inform immunisation policy we have conducted a systematic review and meta-analysis of observation studies to assess population effectiveness against acute gastroenteritis...
August 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28810665/determinants-of-full-vaccination-status-in-children-aged-12-23-months-in-gur%C3%A3-%C3%A3-and-milange-districts-mozambique-results-of-a-population-based-cross-sectional-survey
#3
Shellese A Shemwell, Meridith B Peratikos, Lázaro González-Calvo, Montse Renom-Llonch, Alexandre Boon, Samuel Martinho, Charlotte B Cherry, Ann F Green, Troy D Moon
Background: In 2011, 64% of children in Mozambique, ages 12-23 months, were fully immunized. Large provincial differences in vaccine uptake exist. Methods: We conducted a survey of 1650 females with children aged 12-23 months in the districts of Gurùé and Milange. Implementation occurred from November to December 2014. Descriptive statistics and logistic regression using R-software 3.0.2 were used to examine factors associated with full vaccination status. ArcGIS version 10...
July 1, 2017: International Health
https://www.readbyqxmd.com/read/28809871/-recall-system-for-vaccinations-in-preschool-children-in-a-local-health-unit-in-rome-italy
#4
Aldo Marsico, Cinzia Roscetti, Angelo Fraioli, Chiara Grecuccio, Alessio Cecili, Laura Zaratti, Elisabetta Franco
In Italy, in this period, much attention is dedicated to reach adequate vaccination coverage in children and adolescents. In this study, Vaccination Registry was checked in a Local Health Unit in Rome, Italy, to identify children born in 2007 and 2008 who had not completed the vaccination schedule. Coverage for booster doses of measles, mumps, rubella and for diphtheria, tetanus, pertussis and polio vaccines in the 2213 children was around 70%. A reminder letter was send to parents of the 661 incompletely immunized children and, if they did not reply, a phone call was made when the phone number was available...
May 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28809087/spontaneous-reporting-of-suspected-narcolepsy-after-vaccination-against-pandemic-influenza-a-h1n1-in-germany
#5
Doris Oberle, Jutta Pavel, Brigitte Keller-Stanislawski
PURPOSE: We aimed at investigating whether, in Germany, the number of individual case safety reports (ICSR) of confirmed narcolepsy following Pandemrix® vaccination notified to the Paul-Ehrlich-Institut (PEI, German Federal Institute for Vaccines and Biomedicines) was higher than expected when compared with the prepandemic background incidence rates. METHODS: ICSR of narcolepsy after vaccination with Pandemrix® notified to the PEI until September 2016 were reviewed and validated according to the criteria of narcolepsy defined by the Brighton Collaboration (BC)...
August 14, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28808938/advances-in-vaccines-to-prevent-viral-respiratory-illnesses-in-children
#6
Aleisha J Anderson, Tom L Snelling, Hannah C Moore, Christopher C Blyth
Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens. Acute lower respiratory infection (ALRI) of both bacterial and viral aetiology continues to impact global child health. Key bacterial pathogens including Streptococcus pneumoniae and Haemophilus influenza type b are specifically targeted with current vaccination programmes, while at present there are less effective strategies for the prevention of viral disease...
August 14, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28808074/trends-in-antibiotic-use-by-birth-season-and-birth-year
#7
Alan C Kinlaw, Til Stürmer, Jennifer L Lund, Lars Pedersen, Michael D Kappelman, Julie L Daniels, Trine Frøslev, Christina D Mack, Henrik Toft Sørensen
OBJECTIVES: We examined 2 birth cohort effects on antibiotic prescribing during the first year of life (henceforth, infancy) in Denmark: (1) the birth season effect on timing and overall occurrence of antibiotic prescribing, and (2) the birth year effect amid emerging nationwide pneumococcal vaccination programs and changing prescribing guidelines. METHODS: We linked data for all live births in Denmark from 2004 to 2012 (N = 561 729) across the National Health Service Prescription Database, Medical Birth Registry, and Civil Registration System...
August 14, 2017: Pediatrics
https://www.readbyqxmd.com/read/28807606/effectiveness-of-different-vaccine-schedules-for-heptavalent-and-13-valent-conjugate-vaccines-against-pneumococcal-disease-in-the-community-of-madrid
#8
P Latasa, M Ordobás, M Garrido-Estepa, A Gil de Miguel, J C Sanz, M D Barranco, E Insúa, L García-Comas
INTRODUCTION: The heptavalent pneumococcal conjugate vaccine (PCV-7) was added to the childhood routine vaccination program in the Community of Madrid in November of 2006 with 3+1 recommended doses and a catch-up for those under 2years old. In June 2010, PCV-7 was replaced by 13-valent vaccine (PCV-13) with 2+1 recommended doses. In July of 2012, the PCV-13 was removed from the funded program and reintroduced again (2+1 recommended doses) in December 2014. In between, children were vaccinated privately with 3+1 recommended doses of PCV-13...
August 11, 2017: Vaccine
https://www.readbyqxmd.com/read/28807604/focusing-on-the-implementation-of-21st-century-vaccines-for-adults
#9
Paolo Bonanni, Guglielmo Bonaccorsi, Chiara Lorini, Francesca Santomauro, Emilia Tiscione, Sara Boccalini, Angela Bechini
Adult immunization is a priority for public health, particularly in countries where an aging population has become increasingly more numerous. Protection against diseases which typically affect adults (like flu, pneumococcal diseases and Herpes zoster), the shift of age of infections which originally affected children (like measles), the decreasing protection with time for infections which need periodical booster doses of vaccines (Tdap), the availability of vaccines which can also impact on adult health (HPV) are only some examples of the importance of implementing targeted vaccination strategies...
August 11, 2017: Vaccine
https://www.readbyqxmd.com/read/28807023/local-measles-vaccination-gaps-in-germany-and-the-role-of-vaccination-providers
#10
Linda Eichner, Stephanie Wjst, Stefan O Brockmann, Kerstin Wolfers, Martin Eichner
BACKGROUND: Measles elimination in Europe is an urgent public health goal, yet despite the efforts of its member states, vaccination gaps and outbreaks occur. This study explores local vaccination heterogeneity in kindergartens and municipalities of a German county. METHODS: Data on children from mandatory school enrolment examinations in 2014/15 in Reutlingen county were used. Children with unknown vaccination status were either removed from the analysis (best case) or assumed to be unvaccinated (worst case)...
August 14, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28806737/effectiveness-of-the-13-valent-pneumococcal-conjugate-vaccine-in-preventing-invasive-pneumococcal-disease-in-children-aged-7-59-months-a-matched-case-control-study
#11
Ángela Domínguez, Pilar Ciruela, Sergi Hernández, Juan José García-García, Núria Soldevila, Conchita Izquierdo, Fernando Moraga-Llop, Alvaro Díaz, Mariona F de Sevilla, Sebastià González-Peris, Magda Campins, Sonia Uriona, Johanna Martínez-Osorio, Anna Solé-Ribalta, Gemma Codina, Cristina Esteva, Ana María Planes, Carmen Muñoz-Almagro, Luis Salleras
BACKGROUND: The 13-valent pneumococcal conjugate vaccine (PCV13) was licensed based on the results of immunogenicity studies and correlates of protection derived from randomized clinical trials of the 7-valent conjugate pneumococcal vaccine. We assessed the vaccination effectiveness (VE) of the PCV13 in preventing invasive pneumococcal disease (IPD) in children aged 7-59 months in a population with suboptimal vaccination coverage of 55%. METHODS: The study was carried out in children with IPD admitted to three hospitals in Barcelona (Spain) and controls matched by hospital, age, sex, date of hospitalization and underlying disease...
2017: PloS One
https://www.readbyqxmd.com/read/28806450/evaluation-of-combination-measles-mumps-rubella-varicella-vaccine-introduction-in-australia
#12
Kristine Macartney, Heather F Gidding, Lieu Trinh, Han Wang, Aditi Dey, Brynley Hull, Karen Orr, Jocelynne McRae, Peter Richmond, Michael Gold, Nigel Crawford, Jennifer A Kynaston, Peter McIntyre, Nicholas Wood
Importance: Incorporating combination vaccines, such as the measles-mumps-rubella-varicella (MMRV) vaccine, into immunization schedules should be evaluated from a benefit-risk perspective. Use of MMRV vaccine poses challenges due to a recognized increased risk of febrile seizures (FSs) when used as the first dose in the second year of life. Conversely, completion by age 2 years of measles, mumps, rubella, and varicella immunization may offer improved disease control. Objective: To evaluate the effect on safety and coverage of earlier (age 18 months) scheduling of MMRV vaccine as the second dose of measles-containing vaccine (MCV) in Australia...
August 14, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28806355/seroprevalence-of-anti-polio-antibodies-in-children-from-polio-high-risk-areas-of-pakistan-a-cross-sectional-survey-2015-2016
#13
Imtiaz Hussain, Ondrej Mach, Atif Habib, Zaid Bhatti, Zamir Suhag, M Steven Oberste, William C Weldon, Roland W Sutter, Sajid B Soofi, Zulfiqar A Bhutta
BACKGROUND: Pakistan is one of the 3 remaining wild poliovirus endemic countries. We collected sera from children to assess the prevalence of poliovirus antibodies in selected high-risk areas for poliovirus transmission. METHODS: Children in 2 age groups (6-11 and 36-48 months) were randomly selected between November 2015 and March 2016 in 6 areas of Pakistan (Sindh Province: Karachi and Kashmore; Khyber Pakhtunkhwa Province: Peshawar, Bannu and Nowshera; Punjab Province: Faisalabad)...
September 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28805672/challenges-in-estimating-vaccine-coverage-in-refugee-and-displaced-populations-results-from-household-surveys-in-jordan-and-lebanon
#14
Timothy Roberton, William Weiss, Shannon Doocy
Ensuring the sustained immunization of displaced persons is a key objective in humanitarian emergencies. Typically, humanitarian actors measure coverage of single vaccines following an immunization campaign; few measure routine coverage of all vaccines. We undertook household surveys of Syrian refugees in Jordan and Lebanon, outside of camps, using a mix of random and respondent-driven sampling, to measure coverage of all vaccinations included in the host country's vaccine schedule. We analyzed the results with a critical eye to data limitations and implications for similar studies...
August 12, 2017: Vaccines
https://www.readbyqxmd.com/read/28804787/burden-of-paediatric-respiratory-syncytial-virus-disease-and-potential-effect-of-different-immunisation-strategies-a-modelling-and-cost-effectiveness-analysis-for-england
#15
Deborah Cromer, Albert Jan van Hoek, Anthony T Newall, Andrew J Pollard, Mark Jit
BACKGROUND: Vaccines and prophylactic antibodies against respiratory syncytial virus (RSV) are in development and likely to be available in the next 5-10 years. The most efficient way to use these products when they become available is an important consideration for public health decision makers. METHODS: We performed a multivariate regression analysis to estimate the burden of RSV in children younger than 5 years in England (UK), a representative high-income temperate country, and used these results to assess the potential effect of different RSV immunisation strategies (targeting vaccination for infants, or pregnant women, or prophylactic antibodies for neonates)...
August 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/28803571/a-national-register-based-study-of-paediatric-varicella-hospitalizations-in-denmark-2010-2016
#16
I G Helmuth, A Poulsen, K Mølbak
Varicella, usually a mild disease of childhood, can also cause complications and hospitalization. Universal varicella immunization is implemented in several countries worldwide, but not in Denmark. Taking advantage of unique national registers, we aimed to estimate the incidence of paediatric varicella hospitalizations and assess determinants for hospitalization. For this purpose, we designed a nationwide, retrospective register study of paediatric varicella hospitalizations and applied a case-cohort design and logistic regression analysis comparing hospitalized varicella patients to a sample of the entire paediatric population in Denmark...
August 14, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28803554/wealth-based-inequality-in-child-immunization-in-india-a-decomposition-approach
#17
Avijit Debnath, Nairita Bhattacharjee
Despite years of health and medical advancement, children still suffer from infectious diseases that are vaccine preventable. India reacted in 1978 by launching the Expanded Programme on Immunization in an attempt to reduce the incidence of vaccine-preventable diseases (VPDs). Although the nation has made remarkable progress over the years, there is significant variation in immunization coverage across different socioeconomic strata. This study attempted to identify the determinants of wealth-based inequality in child immunization using a new, modified method...
August 14, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28803551/hospitalisation-for-lower-respiratory-tract-infection-in-children-in-the-province-of-quebec-canada-before-and-during-the-pneumococcal-conjugate-vaccine-era
#18
G Anderson, G Deceuninck, Z Zhou, F D Boucher, Y Bonnier Viger, R Gilca, P DE Wals
Streptococcus pneumoniae is an important cause of community-acquired pneumonia and pneumococcal conjugate vaccines (PCVs) may reduce this burden. This study's goal was to analyse trends in lower respiratory tract infections (LRTI) hospitalisations before and during a routine vaccination programme targeting all newborns with PCV was started in the province of Quebec, Canada in December 2004. The study population included hospital admissions with a main diagnosis of LRTI among 6-59 month-old Quebec residents from April 2000 to December 2014...
August 14, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28803415/a-measles-outbreak-in-sindh-pakistan-caused-by-a-genotype-b3-virus
#19
Syed Sohail Zahoor Zaidi, Abdul Hameed, Naeem Ali, Massab Umair, Muhammad Masroor Alam, Muhammad Suleman Rana, Salmaan Sharif, Uzma Bashir Aamir, Shahzad Shaukat, Mehar Angez, Adnan Khurshid, Ribqa Akhtar, Nayab Mehmood, Nazish Badar
Measles continues to be a major public health issue causing substantial outbreaks worldwide, mostly affecting young children. Molecular analysis of measles viruses provides important information on outbreak linkages and transmission pathways that can be helpful towards implementation of appropriate control programs. In Pakistan, the control of measles is still tenuous, and progress towards elimination has been irregular and challenging. In the 2013 measles outbreak we received 4,682 sera collected from suspected patients in 23 districts across Sindh...
August 12, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28803259/opportunities-and-challenges-in-the-immunological-therapy-of-pediatric-malignancy-a-concise-snapshot
#20
REVIEW
Francesco Ceppi, Maja Beck-Popovic, Jean-Pierre Bourquin, Raffaele Renella
Over the last 50 years, collaborative clinical trials have reduced the number of children dying from pediatric cancer significantly. Unfortunately, certain tumor types have remained resistant to conventional surgical, radiotherapy and chemotherapy combinations, and relapsing and/or refractory disease remains associated with dismal outcomes. Recently, renewed attention has been given to the role for immunotherapies in pediatric oncology. In fact, these combine several attractive features, including (but possibly not limited to) the specificity for cancer cells, potentially in vivo persistence and longevity, and potency against refractory disease...
August 12, 2017: European Journal of Pediatrics
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