keyword
https://read.qxmd.com/read/38498042/quality-assessment-of-smartphone-medication-management-apps-in-france-systematic-search
#1
JOURNAL ARTICLE
Mickael Toïgo, Julie Marc, Maurice Hayot, Lionel Moulis, Francois Carbonnel
BACKGROUND: Adherence to medication is estimated to be around 50% for chronically ill patients in high-income countries. Improving the effectiveness of adherence interventions could have a far greater impact on population health than any improvement in specific medical treatments. Mobile health (mHealth) is one of the most effective solutions for helping patients improve their medication intake, notably through the use of mobile apps with reminder systems. With more than 327,000 apps available in the mHealth field, it is difficult for health care professionals and patients alike to choose which apps to recommend and use...
March 18, 2024: JMIR MHealth and UHealth
https://read.qxmd.com/read/38497958/leveraging-large-language-models-for-generating-responses-to-patient-messages-a-subjective-analysis
#2
JOURNAL ARTICLE
Siru Liu, Allison B McCoy, Aileen P Wright, Babatunde Carew, Julian Z Genkins, Sean S Huang, Josh F Peterson, Bryan Steitz, Adam Wright
OBJECTIVE: This study aimed to develop and assess the performance of fine-tuned large language models for generating responses to patient messages sent via an electronic health record patient portal. MATERIALS AND METHODS: Utilizing a dataset of messages and responses extracted from the patient portal at a large academic medical center, we developed a model (CLAIR-Short) based on a pre-trained large language model (LLaMA-65B). In addition, we used the OpenAI API to update physician responses from an open-source dataset into a format with informative paragraphs that offered patient education while emphasizing empathy and professionalism...
March 18, 2024: Journal of the American Medical Informatics Association: JAMIA
https://read.qxmd.com/read/38497687/discordance-therapeutic-protocol-of-cystic-echinococcosis-with-who-guideline-a-descriptive-study-based-on-liver-ultra-sonographic-data-in-north-khorasan-province-northeastern-of-iran
#3
JOURNAL ARTICLE
Reza Shafiei, Mina Sadat Mohajerzadeh, Hajar Farah Abad Masomi, Maryam Tavakoli, Habibollah Turki, Nima Firouzeh
BACKGROUND: Cystic echinococcosis (CE), a helminth-associated zoonosis caused by Echinococcus granulosus, poses a significant public health problem, particularly in pastoral-rearing regions. The lack of uniform guidelines led to variations in CE management. Based on ultrasound data, the World Health Organization Informal Working Group on Echinococcosis (WHO-IWGE) classification system categorizes cysts into active, transitional, and inactive groups. This study assesses whether the therapeutic approach from liver human operation cases in North Khorasan province aligns with the WHO-IWGE reference based on ultrasound data...
March 18, 2024: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://read.qxmd.com/read/38497068/knowledge-perception-and-usage-of-e-learning-among-medical-undergraduates-in-andhra-pradesh-india
#4
JOURNAL ARTICLE
Roza Bhaisare, Shahana Syed, Gaurav Rangari
Electronic gadgets help to get study material outside classroom and it is used for self-directed learning which helps user to overcome limitations of Conventional teaching methods. Medical education is constantly growing and evolving with rapid speed. So, it is necessary to keep the upcoming medical graduates and established medical practitioners updated in this competitive world. For this, E-learning is the important tool in the medical field. This cross-sectional study was conducted in the medical college of Andhra Pradesh...
2024: Bioinformation
https://read.qxmd.com/read/38496160/laparoscopic-management-of-inguinal-hernia-a-systematic-review-and-updated-network-meta-analysis-of-randomized-controlled-trials
#5
REVIEW
Hadeel Almutairi, Reem S Alshammari, Majed J Alharbi, Dana M Althobaiti, Raghad S Alghamdi, Samar Alsamiri, Sara W Mawash, Duaa A Ahmed, Abdulrahman A Alamoudi, Fai Y Arif, Fatimah M Albrahim, Mohammed Alfehaid, Haneen W Alanzy
Various surgical approaches for inguinal hernia repair have been outlined in medical literature. In most cases, these lesions are repaired by general surgeons. A variety of surgical techniques for the treatment of inguinal hernias have been documented in the medical literature. In 2018, the European Hernia Society (EHS) recommended laparo-endoscopic repair as a preferred approach for adults. This method involves a combination of laparoscopic and endoscopic techniques for hernia repair. The goal of this systematic review is to conduct a thorough examination of the total extraperitoneal vs...
February 2024: Curēus
https://read.qxmd.com/read/38495657/spectrum-of-ischemic-heart-disease-throughout-a-woman-s-life-cycle
#6
REVIEW
Smitha Narayana Gowda, Sai Sita Garapati, Karla Kurrelmeyer
Ischemic heart disease (IHD) is the leading cause of morbidity and mortality in both genders; however, young women fare the worst, likely reflecting the more complex spectrum of IHD in women when compared to men. Substantial sex-based differences exist in the underlying risk factors, risk enhancers, presentation, diagnosis, and pathophysiology of IHD that are mainly attributed to the influence of female sex hormones. This article reviews the spectrum of IHD including obstructive epicardial coronary artery disease (CAD), myocardial infarction with no obstructive coronary artery disease, ischemia with no obstructive coronary artery disease, spontaneous coronary artery dissection, coronary microvascular dysfunction, vasospastic angina, and coronary thrombosis/embolism that occur in women throughout various stages of their life cycle...
2024: Methodist DeBakey Cardiovascular Journal
https://read.qxmd.com/read/38495246/external-validation-and-updating-of-published-models-for-predicting-7-day-risk-of-symptomatic-intracranial-hemorrhage-after-receiving-alteplase-for-acute-ischemic-stroke-a-retrospective-cohort-study
#7
JOURNAL ARTICLE
Phaweesa Chawalitpongpun, Paveena Sonthisombat, Napacha Piriyachananusorn, Natthakarn Manoyana
BACKGROUND: Prediction scores for symptomatic intracranial hemorrhage (sICH) in acute ischemic stroke patients receiving thrombolytic therapy have been widely developed, but the external validation of these scores, especially in the Thai population, is lacking. This study aims to externally validate existing models and update the selected model to enhance its performance in our specific context. METHODS: This cohort study retrospectively collected data from medical records between 2013 and 2022...
2024: Annals of Indian Academy of Neurology
https://read.qxmd.com/read/38494767/-introduction-to-the-9-th-edition-of-tnm-classification-for-lung-cancer
#8
JOURNAL ARTICLE
B Zhang, W T Fang, H Zhong
Lung cancer is the second commonly diagnosed cancer and remained the leading cause of cancer-related death, with an estimated 1.8 million deaths in 2020. The identification of driver gene mutation and administration of corresponding tyrosine kinase inhibitor have improved overall survival and quality of life in advanced lung cancer patients. Check point inhibitor has revolutionized treatment strategy of driver gene negative advanced NSCLC patients. TNM staging system is the most widely used classification method, providing an international common language during academic communication and important tool for predicting prognosis and subsequent treatment decision making...
March 23, 2024: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://read.qxmd.com/read/38493024/college-health-centers-an-update-on-medical-issues
#9
JOURNAL ARTICLE
Ariel Tassy Nunez
College health centers are an important source of health care for large numbers of young adults throughout the country. With 16.9 million students enrolled in 2023 in post-secondary institutions in the United States, the potential impact that health centers at these institutions have is significant. Late adolescence and early adulthood is a particularly vulnerable stage of both cognitive and psychosocial development, and college health centers that provide comprehensive medical and mental-health care play an important role in providing comprehensive care for this age group...
March 15, 2024: Current Problems in Pediatric and Adolescent Health Care
https://read.qxmd.com/read/38492632/pediatric-utilization-of-emergency-medical-services-from-outpatient-offices-and-urgent-care-centers
#10
JOURNAL ARTICLE
Jennifer K Saper, Michelle L Macy, Christian Martin-Gill, Sriram Ramgopal
OBJECTIVE: National efforts have highlighted the need for pediatric emergency readiness across all settings where children receive care. Outpatient offices and urgent care centers are frequent starting points for acutely injured and ill children, emphasizing the need to maintain pediatric readiness in this setting. We aimed to characterize emergency medical services (EMS) utilization from outpatient offices and urgent care centers to better understand pediatric readiness needs. METHODS: We performed a retrospective cross-sectional analysis of EMS encounters using the National Emergency Medical Services Information System, a nationally representative EMS registry (2019-2022)...
March 14, 2024: Academic Pediatrics
https://read.qxmd.com/read/38492173/the-role-of-mitochondria-in-statin-induced-myopathy
#11
REVIEW
Gavin Bell, Anastasia Thoma, Iain P Hargreaves, Adam P Lightfoot
Statins represent the primary therapy for combatting hypercholesterolemia and reducing mortality from cardiovascular events. Despite their pleiotropic effects in lowering cholesterol synthesis, circulating cholesterol, as well as reducing the risk of other systemic diseases, statins have adverse events in a small, but significant, population of treated patients. The most prominent of these adverse effects is statin-induced myopathy, which lacks precise definition but is characterised by elevations in the muscle enzyme creatine kinase alongside musculoskeletal complaints, including pain, weakness and fatigue...
March 16, 2024: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://read.qxmd.com/read/38492092/comparison-of-the-efficacy-and-safety-of-benzbromarone-and-febuxostat-in-gout-and-hyperuricemia-a-systematic-review-and-meta-analysis
#12
JOURNAL ARTICLE
Fan Wu, Lvyi Chen, Yimei Du
OBJECTIVE: Urate-lowering therapy (ULT) is widely recognized as the primary treatment for hyperuricemia and gout. Xanthine oxidase inhibitors (XOI), particularly febuxostat, have gained popularity as a frontline approach. However, the divergent efficacy and safety between febuxostat and the traditional ULT drug, benzbromarone, remain poorly understood. This knowledge gap necessitates a comprehensive analysis and evidence update to guide drug selection for physicians and patients. METHOD: We conducted a systematic analysis by extracting relevant clinical studies from four medical literature databases...
March 16, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38491743/an-update-on-clinical-trials-for-cutaneous-lupus-erythematosus
#13
REVIEW
Lillian Xie, Lais Lopes Almeida Gomes, Caroline J Stone, Daniella Forman Faden, Victoria P Werth
Cutaneous lupus erythematosus (CLE) comprises dermatologic manifestations that may occur independently or with systemic lupus erythematosus (SLE). Despite advancements in refining CLE classification, establishing precise subtype criteria remains challenging due to overlapping presentations and difficulty in distinguishing morphology. Current treatments encompass preventive measures, topical therapies, and systemic approaches. Hydroxychloroquine and glucocorticoids are the sole US Food and Drug Administration (FDA)-approved medications for CLE, with numerous off-label treatments available...
March 15, 2024: Journal of Dermatology
https://read.qxmd.com/read/38491397/development-and-effectiveness-of-a-boppps-teaching-model-based-workshop-for-community-pharmacists-training
#14
JOURNAL ARTICLE
Bingzheng Shen, Yating Chen, Yue Wu, Yu Lan, Xiaoqin He, Na Wang, Jun Liu, Yan Yu
BACKGROUND/AIM: With the pharmaceutical innovation and clinical knowledge updating, the continuing education and on-the-job training are extremely important for improving community pharmacists' professional competence. Previous training often adopted traditional lecture-based teaching, and the efficacy was limited. The aim of this study is to develop a new strategy for community pharmacist training. METHODS: Based on the BOPPPS (Bridge-in, Objective, Pre-assessment, Participatory Learning, Post-assessment and Summary) teaching model and workshop method, a continuing on-the-job training program was constructed...
March 15, 2024: BMC Medical Education
https://read.qxmd.com/read/38491382/factors-associated-with-modern-contraceptive-utilization-among-reproductive-age-women-in-kenya-evidenced-by-the-2022-kenyan-demographic-and-health-survey
#15
JOURNAL ARTICLE
Gosa Mankelkl, Altaseb Beyene Kassaw, Beletu Kinfe
BACKGROUND: Globally, sexual and reproductive health is a significant public health issue for women of the reproductive age group. A modern contraceptive method enables individuals and families to manage fertility by reducing unintended pregnancies, abortions, pregnancy-related morbidity, and death. A modern contraceptive method is a drug or medical treatment that prevents sexual activity from leading to pregnancy. However, there is limited reliable and updated data on factors associated with modern contraceptive utilization among reproductive-age women at the national level in Kenya...
March 15, 2024: Contraception and Reproductive Medicine
https://read.qxmd.com/read/38490358/esmo-clinical-practice-guideline-interim-update-on-first-line-therapy-in-advanced-urothelial-carcinoma
#16
T Powles, J Bellmunt, E Comperat, M De Santis, R Huddart, Y Loriot, A Necchi, B P Valderrama, A Ravaud, S F Shariat, B Szabados, M S van der Heijden, S Gillessen
No abstract text is available yet for this article.
March 13, 2024: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://read.qxmd.com/read/38490042/liquid-chromatography-coupled-to-tandem-mass-spectrometry-lc-ms-ms-methods-for-the-therapeutic-drug-monitoring-of-cytotoxic-anticancer-drugs-an-update
#17
REVIEW
M Briki, A Murisier, M Guidi, C Seydoux, T Buclin, C Marzolini, F R Girardin, Y Thoma, S Carrara, E Choong, L A Decosterd
In the era of precision medicine, there is increasing evidence that conventional cytotoxic agents may be suitable candidates for therapeutic drug monitoring (TDM)- guided drug dosage adjustments and patient's tailored personalization of non-selective chemotherapies. To that end, many liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) assays have been developed for the quantification of conventional cytotoxic anticancer chemotherapies, that have been comprehensively and critically reviewed...
February 3, 2024: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://read.qxmd.com/read/38487794/the-paper-chase-a-team-science-training-exercise
#18
JOURNAL ARTICLE
Kristin J Perry, Lauren M Mutignani, Jordan Gette, Kerry L Kinney, Tre D Gissandaner, Francesca Penner, Alainna Wen, Timothy Regan, Crystal Lim
Over the past few decades of psychological research, there has been an important increase in both the application of multidisciplinary or collaborative science and in training and research that emphasizes social justice and cultural humility. In the current paper, we report on the use of the "Paper Chase" as a team science training and research experience that also facilitates cultural humility in research and when working in teams. The Paper Chase is a synchronous writing exercise originally conceptualized by a cohort of health service psychology interns to reduce lag time between manuscript writing and submission (Schaumberg et al...
February 2024: Training and Education in Professional Psychology
https://read.qxmd.com/read/38486447/car-t-cell-therapy-for-diffuse-large-b-cell-lymphoma-in-canada-a-cost-utility-analysis
#19
JOURNAL ARTICLE
Lisa Masucci, Feng Tian, Stephen Tully, Zeny Feng, Tom McFarlane, Kelvin K W Chan, William W L Wong
BACKGROUND: Chimeric antigen receptor (CAR) T-cell therapy is a novel cell therapy for treating non-Hodgkin lymphoma. The development of CAR T-cell therapy has transformed oncology treatment by offering a potential cure. However, due to the high cost of these therapies, and the large number of eligible patients, decision makers are faced with difficult funding decisions. Our objective was to assess the cost-effectiveness of tisagenlecleucel for adults with relapsed/refractory diffuse large B-cell lymphoma in Canada using updated survival data from the recent JULIET trial...
March 14, 2024: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://read.qxmd.com/read/38486388/role-of-phytoactive-based-nanoformulation-for-the-treatment-of-arthritis
#20
JOURNAL ARTICLE
Shivendra Kumar, Kantrol Kumar Sahu, Mohit Agrawal, Kuldeep Singh, Sunam Saha
Joints and arthritic conditions are among the most dangerous illnesses that humans have ever encountered and it is even more worrying that there is no recognized treatment for arthritis. The researchers looked for safer alternatives, such as herbal medicines, because the traditional treatments used to treat severe joint inflammatory issues have several negative side effects. A ligand-coated nanomedicine can bind to receptors that are overexpressed by cells in chronically inflammatory tissues, increasing its efficacy and reducing its systemic side effects...
March 14, 2024: Current Pharmaceutical Biotechnology
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