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https://www.readbyqxmd.com/read/28100379/-cost-effectiveness-analysis-on-colorectal-cancer-screening-program
#1
Q C Huang, D Ye, X Y Jiang, Q L Li, K Y Yao, J B Wang, M J Jin, K Chen
Objective: To evaluate the cost-effectiveness of colorectal cancer screening program in different age groups from the view of health economics. Methods: The screening compliance rates, detection rates in different age groups were calculated by using the data from colorectal cancer screening program in Jiashan county, Zhejiang province. The differences in indicator among age groups were analyzed with χ(2) test or trend χ(2) test. The ratios of cost to the number of case were calculated according to cost statistics...
January 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28097082/a-review-of-colorectal-cancer-detection-modalities-stool-dna-and-fecal-immunochemistry-testing-in-adults-over-the-age-of-50
#2
REVIEW
Tyler Janz, Karen Lu, Michael R Povlow, Brittany Urso
Colorectal cancer (CRC) is the third leading cause of cancer death in the United States. Recently, more focus has been placed on developing effective screening tools to detect the presence of both precancerous and cancerous lesions present in the colon and rectum. Colonoscopy has been well established as the gold standard of the colon and rectal cancer screening. However, not all patients are willing to undergo a colonoscopy due to the procedure's invasive nature. Non-invasive screening methods have been developed to appeal to patients who refuse colonoscopy...
December 16, 2016: Curēus
https://www.readbyqxmd.com/read/28076249/fecal-immunochemical-test-fit-for-colon-cancer-screening-variable-performance-with-ambient-temperature
#3
Chyke A Doubeni, Christopher D Jensen, Stacey A Fedewa, Virginia P Quinn, Ann G Zauber, Joanne E Schottinger, Douglas A Corley, Theodore R Levin
INTRODUCTION: Fecal immunochemical tests (FITs) are widely used in colorectal cancer (CRC) screening, but hemoglobin degradation, due to exposure of the collected sample to high temperatures, could reduce test sensitivity. We examined the relation of ambient temperature exposure with FIT positivity rate and sensitivity. METHODS: This was a retrospective cohort study of patients 50 to 75 years in Kaiser Permanente Northern California's CRC screening program, which began mailing FIT kits annually to screen-eligible members in 2007...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28076242/bread-and-butter-of-family-medicine-guidelines-population-screening-diagnostic-evaluations-and-practice-models
#4
EDITORIAL
Dean A Seehusen, Marjorie A Bowman, Anne Victoria Neale
This issue of JABFM is full of evidence and thoughtful articles on topics central to family medicine. These articles critically examine what family physicians do on a daily basis. Reports in this issue provide new evidence regarding guidelines, screening programs, evaluation procedures, and practice models. Clinical articles report that the sensitivity of mailed Fecal Immunochemical Testing changes with the weather; a dermatoscope and a simple algorithm can help differentiate malignant from benign skin lesions; and that a few almonds can alter blood glucose levels in response to a glucose tolerance test...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28065631/the-fecal-immunochemical-test-has-high-accuracy-for-detecting-advanced-colorectal-neoplasia-before-age-50
#5
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
BACKGROUND: In contrast to the decreasing incidence of colorectal cancer (CRC) in adults ≥50 years, the CRC incidence in young adults <50 years is increasing. The fecal immunochemical test (FIT) may be useful for advanced colorectal neoplasia (ACRN) screening in a young population. AIMS: To evaluate the diagnostic accuracy of FIT in a young population. METHODS: The diagnostic performance of FIT for detecting ACRN was compared among the following age groups who underwent FIT and colonoscopy as part of a comprehensive health screening program: 30-39, 40-49, and ≥50 years...
December 24, 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28044229/genetic-biomarker-prevalence-is-similar-in-fecal-immunochemical-test-positive-and-negative-colorectal-cancer-tissue
#6
Theodore R Levin, Douglas A Corley, Christopher D Jensen, Amy R Marks, Wei K Zhao, Alexis M Zebrowski, Virginia P Quinn, Lawrence W Browne, William R Taylor, David A Ahlquist, Graham P Lidgard, Barry M Berger
BACKGROUND: Fecal immunochemical test (FIT) screening detects most asymptomatic colorectal cancers. Combining FIT screening with stool-based genetic biomarkers increases sensitivity for cancer, but whether DNA biomarkers (biomarkers) differ for cancers detected versus missed by FIT screening has not been evaluated in a community-based population. AIMS: To evaluate tissue biomarkers among Kaiser Permanente Northern California patients diagnosed with colorectal cancer within 2 years after FIT screening...
January 2, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28042387/colorectal-cancer-screening-opportunities-to-improve-uptake-outcomes-and-disparities
#7
REVIEW
Neal Shahidi, Winson Y Cheung
Colorectal cancer screening has become a standard of care in industrialized nations for those 50 to 75 years of age, along with selected high-risk populations. While colorectal cancer screening has been shown to reduce both the incidence and mortality of colorectal cancer, it is a complex multi-disciplinary process with a number of important steps that require optimization before tangible improvements in outcomes are possible. For both opportunistic and programmatic colorectal cancer screening, poor participant uptake remains an ongoing concern...
December 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28018880/performance-of-a-quantitative-fecal-immunochemical-test-in-a-colorectal-cancer-screening-pilot-program-a-prospective-cohort-study
#8
Jennifer Telford, Laura Gentile, Lovedeep Gondara, Colleen McGahan, Andrew Coldman
BACKGROUND: British Columbia undertook a colorectal cancer screening pilot program in 3 communities. Our objective was to assess the performance of 2-specimen fecal immunochemical testing in the detection of colorectal neoplasms in this population-based screening program. METHODS: A prospective cohort of asymptomatic, average-risk people aged 50 to 74 years completed 2 quantitative fecal immunochemical tests every 2 years, with follow-up colonoscopy if the result of either test was positive...
October 2016: CMAJ Open
https://www.readbyqxmd.com/read/27986704/comparison-of-collection-methods-for-fecal-samples-in-microbiome-studies
#9
Emily Vogtmann, Jun Chen, Amnon Amir, Jianxin Shi, Christian C Abnet, Heidi Nelson, Rob Knight, Nicholas Chia, Rashmi Sinha
Prospective cohort studies are needed to assess the relationship between the fecal microbiome and human health and disease. To evaluate fecal collection methods, we determined technical reproducibility, stability at ambient temperature, and accuracy of 5 fecal collection methods (no additive, 95% ethanol, RNAlater Stabilization Solution, fecal occult blood test cards, and fecal immunochemical test tubes). Fifty-two healthy volunteers provided fecal samples at the Mayo Clinic in Rochester, Minnesota, in 2014...
December 16, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27978410/influences-and-practices-in-colorectal-cancer-screening-among-health-care-providers-serving-northern-plains-american-indians-2011-2012
#10
Melanie Nadeau, Anne Walaszek, David G Perdue, Kristine L Rhodes, Donald Haverkamp, Jean Forster
INTRODUCTION: The epidemiology of colorectal cancer, including incidence, mortality, age of onset, stage of diagnosis, and screening, varies regionally among American Indians. The objective of the Improving Northern Plains American Indian Colorectal Cancer Screening study was to improve understanding of colorectal cancer screening among health care providers serving Northern Plains American Indians. METHODS: Data were collected, in person, from a sample of 145 health care providers at 27 health clinics across the Northern Plains from May 2011 through September 2012...
December 15, 2016: Preventing Chronic Disease
https://www.readbyqxmd.com/read/27936028/cost-effectiveness-of-screening-colonoscopy-depends-on-adequate-bowel-preparation-rates-a-modeling-study
#11
James Kingsley, Siddharth Karanth, Frances Lee Revere, Deepak Agrawal
BACKGROUND: Inadequate bowel preparation during screening colonoscopy necessitates repeating colonoscopy. Studies suggest inadequate bowel preparation rates of 20-60%. This increases the cost of colonoscopy for our society. AIM: The aim of this study is to determine the impact of inadequate bowel preparation rate on the cost effectiveness of colonoscopy compared to other screening strategies for colorectal cancer (CRC). METHODS: A microsimulation model of CRC screening strategies for the general population at average risk for CRC...
2016: PloS One
https://www.readbyqxmd.com/read/27906448/a-randomized-controlled-trial-of-a-multicomponent-targeted-low-literacy-educational-intervention-compared-with-a-nontargeted-intervention-to-boost-colorectal-cancer-screening-with-fecal-immunochemical-testing-in-community-clinics
#12
Stacy N Davis, Shannon M Christy, Enmanuel A Chavarria, Rania Abdulla, Steven K Sutton, Alyssa R Schmidt, Susan T Vadaparampil, Gwendolyn P Quinn, Vani N Simmons, Chukwudi B Ufondu, Chitra Ravindra, Ida Schultz, Richard G Roetzheim, David Shibata, Cathy D Meade, Clement K Gwede
BACKGROUND: The objective of the current study was to improve colorectal cancer (CRC) screening uptake with the fecal immunochemical test (FIT). The current study investigated the differential impact of a multicomponent, targeted, low-literacy educational intervention compared with a standard, nontargeted educational intervention. METHODS: Patients aged 50 to 75 years who were of average CRC risk and not up-to-date with CRC screening were recruited from either a federally qualified health center or a primary care community health clinic...
December 1, 2016: Cancer
https://www.readbyqxmd.com/read/27905896/the-impact-of-medical-tourism-on-colorectal-screening-among-korean-americans-a-community-based-cross-sectional-study
#13
Linda K Ko, Victoria M Taylor, Jihye Yoon, Wade K Copeland, Joo Ha Hwang, Eun Jeong Lee, John Inadomi
BACKGROUND: Colorectal cancer (CRC) remains the most commonly diagnosed cancer among Korean Americans (KAs) in part due to low screening rates. Recent studies suggest that some KA patients engage in medical tourism and receive medical care in their home country. The impact of medical tourism on CRC screening is unknown. The purpose of this paper was to 1) investigate the frequency of medical tourism, 2) examine the association between medical tourism and CRC screening, and 3) characterize KA patients who engage in medical tourism...
December 1, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27895817/current-noninvasive-tests-for-colorectal-cancer-screening-an-overview-of-colorectal-cancer-screening-tests
#14
REVIEW
Le-Le Song, Yue-Min Li
Colorectal cancer (CRC) has become the third most common cancer in the world. Screening has been shown to be an effective way to identify early CRC and precancerous lesions, and to reduce its morbidity and mortality. Several types of noninvasive tests have been developed for CRC screening, including the fecal occult blood test (FOBT), the fecal immunochemical test (FIT), the fecal-based DNA test and the blood-based DNA test (the SEPT9 assay). FIT has replaced FOBT and become the major screening test due to high sensitivity, specificity and low costs...
November 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/27893135/screening-for-colorectal-cancer-and-evolving-issues-for-physicians-and-patients-a-review
#15
REVIEW
David Lieberman, Uri Ladabaum, Marcia Cruz-Correa, Carla Ginsburg, John M Inadomi, Lawrence S Kim, Francis M Giardiello, Richard C Wender
Importance: Colorectal cancer (CRC) is the second-leading cause of cancer death in the United States. Screening can reduce CRC mortality and incidence, and numerous screening options, although available, complicate informed decision making. This review provides evidence-based tools for primary care physicians to identify patients with higher-than-average-risk and engage patients in informed decision making about CRC screening options. Observations: Recently, the US Preventive Services Task Force recommended any of 8 CRC screening approaches for average-risk individuals, beginning at age 50 years...
November 22, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27890769/real-time-monitoring-of-results-during-first-year-of-dutch-colorectal-cancer-screening-program-and-optimization-by-altering-fecal-immunochemical-test-cut-off-levels
#16
Esther Toes-Zoutendijk, Monique E van Leerdam, Evelien Dekker, Frank van Hees, Corine Penning, Iris Nagtegaal, Miriam P van der Meulen, Anneke J van Vuuren, Ernst J Kuipers, Johannes M G Bonfrer, Katharina Biermann, Maarten G J Thomeer, Harriët van Veldhuizen, Sonja Kroep, Marjolein van Ballegooijen, Gerrit A Meijer, Harry J de Koning, Manon C W Spaander, Iris Lansdorp-Vogelaar
BACKGROUND AND AIM: After careful pilot studies and planning, the national screening program for colorectal cancer (CRC), with biennial fecal immunochemical tests (FITs), was initiated in the Netherlands in 2014. A national information system for real-time monitoring was developed to allow for timely evaluation. Data was collected from the first year of this screening program to determine the importance of planning and monitoring for optimal screening program performance. METHODS: The national information system of the CRC screening program kept track on the number of invitations sent in 2014, FIT kits returned, and colonoscopies performed...
November 24, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27873508/are-hemorrhoids-associated-with-false-positive-fecal-immunochemical-test-results
#17
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
PURPOSE: False-positive (FP) results of fecal immunochemical tests (FITs) conducted in colorectal cancer (CRC) screening could lead to performing unnecessary colonoscopies. Hemorrhoids are a possible cause of FP FIT results; however, studies on this topic are extremely rare. We investigated whether hemorrhoids are associated with FP FIT results. MATERIALS AND METHODS: A retrospective study was conducted at a university hospital in Korea from June 2013 to May 2015...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27853376/diagnosis-reliability-of-combined-flexible-sigmoidoscopy-and-fecal-immunochemical-test-in-colorectal-neoplasia-screening
#18
Dana Iovanescu, Mirela Frandes, Diana Lungeanu, Amelia Burlea, Bogdan P Miutescu, Eftimie Miutescu
BACKGROUND: Employing colonoscopy, the gold standard in colorectal cancer (CRC) diagnosis testing, for CRC screening presents a significant risk of complications. Alternative methods with a lower invasive-level and fewer risks are proposed in combination, though each with lower diagnosis performance when applied separately. The main objective of this cross-sectional pilot study was to evaluate the feasibility of a CRC screening program using combined flexible sigmoidoscopy and fecal-immunochemical test (FIT)...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27847280/serrated-polyp-detection-by-the-fecal-immunochemical-test-an-imperfect-fit
#19
EDITORIAL
Joseph C Anderson, Douglas J Robertson
No abstract text is available yet for this article.
November 12, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27842559/dna-from-fecal-immunochemical-test-can-replace-stool-for-detection-of-colonic-lesions-using-a-microbiota-based-model
#20
Nielson T Baxter, Charles C Koumpouras, Mary A M Rogers, Mack T Ruffin, Patrick D Schloss
BACKGROUND: There is a significant demand for colorectal cancer (CRC) screening methods that are noninvasive, inexpensive, and capable of accurately detecting early stage tumors. It has been shown that models based on the gut microbiota can complement the fecal occult blood test and fecal immunochemical test (FIT). However, a barrier to microbiota-based screening is the need to collect and store a patient's stool sample. RESULTS: Using stool samples collected from 404 patients, we tested whether the residual buffer containing resuspended feces in FIT cartridges could be used in place of intact stool samples...
November 14, 2016: Microbiome
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