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Sodium Potassium ratio

Pinar Karakaya, Bahar Ozdemir, Meral Mert, Yildiz Okuturlar
AIM: The sodium-sparing effect of insulin leads to increase in total sodium pool of the body which is a chronic stimulus for atrial natriuretic peptide (ANP). In our study we aimed to determine the relationship between ANP and microvascular complications of diabetes. METHODS: 60 patients, 30-70 years old, with the diagnosis of type 2 diabetes mellitus (DM) are enrolled into the study. Patients with a chronic disease other than DM are excluded. Blood samples for routine biochemical tests are taken after at least 12 h fasting at 8-9 am...
February 14, 2018: Obesity Facts
Li-Juan Wang, Qi-Jiong Li, Yong Le, Han-Yue Ouyang, Min-Ke He, Zi-Shan Yu, Yong-Fa Zhang, Ming Shi
The clinical significance of the sodium-potassium ATPase regulator FXYD domain-containing ion transport regulator 3 (FXYD3) has been demonstrated in a number of types of cancer. However, the role of this protein in human hepatocellular carcinoma (HCC) remains to be elucidated. In the present study, 217 HCC tissue samples were analyzed to evaluate the expression and prognostic significance of FXYD3 in HCC. Reverse transcription-quantitative polymerase chain reaction was used to analyze the mRNA expression of FXYD3 in 80 primary HCC specimens and paired non-cancerous liver tissue samples, while western blotting was used to analyze the protein expression level of FXYD3 in another 24 pairs...
March 2018: Oncology Letters
Salar Farhangi-Abriz, Shahram Torabian
A pot experiment was conducted with three biochar ratios (non-biochar, 5, and 10% total pot mass) and three salinities (control, 6, and 12 dSm-1 sodium chloride) treatments. At the flowering stage, we harvested common bean (Phaseolus vulgaris L. cv. Derakhshan) plants and measured growth characteristics and nutrient contents. As an average, salt stress decreased shoot and root dry weight, leaf area, relative water content, chlorophyll fluorescence (Fv/Fm) and leaf chlorophyll content, however, increased root length, sodium (Na) content of root and shoot, Na uptake, and translocation of bean plants, compared to control...
February 9, 2018: Environmental Science and Pollution Research International
Xiao Sun, Jihui Chen, Lisheng Liu, Andrea Rosanoff, Xue Xiong, Yingjun Zhang, Tongtong Pei
Magnesium (Mg) is important for both plant photosynthesis and protein-synthesis. Nevertheless, latent Mg deficiencies are common, and Mg addition has shown improved yield. Might such increasing yield cause "hidden" hunger for microelements and protein, and if so, what is the mechanism? We conducted two greenhouse experiments using low-Mg soil to investigate: (i) effects of 5 levels of Mg fertilizer (20 to 400 mg kg-1) on 8 elements and crude protein concentrations in annual ryegrass and perennial white clover; (ii) if any protein effects of Mg fertilizer depend on soil nitrogen (N)...
February 5, 2018: Journal of Agricultural and Food Chemistry
Ali-Akbar Mozafari, Ali Ghadakchi Asl, Nasser Ghaderi
Grape softwood cuttings of Khoshnaw cultivar were cultured using tissue-culture methods to study the effect of iron nanoparticles and potassium silicate under salinity conditions during the 2015-2016 growing season. The treatments consisted of salinity stress (0, 50, and 100 mM NaCl), nanoparticles of iron (0, 0.08, and 0.8 ppm), and potassium silicate (0, 1, 2 mM). The results also showed that the application of iron nanoparticles and potassium silicate significantly increased the total protein content and reduced proline, enzymatic antioxidant activity and hydrogen peroxide...
February 2018: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
M Kavitha, K Mubeen, K R Vijayalakshmi
Objectives: Squamous cell carcinoma is the most common oral cancer. Radiotherapy with concomitant chemotherapy is an ideal treatment modality largely used for oral cancers, which precipitates many side effects, of which the most challenging and debilitating side effect is xerostomia. This study aimed to evaluate the efficacy of bethanechol in patients with xerostomia following chemoradiation therapy for oral cancer. Materials and Methods: Fifty patients with xerostomia postchemoradiation therapy, aged between 30 and 65 years, were selected based on selection criteria...
September 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
Claudia Shu-Fen Leong, Ciarán G Forde, Siew Ling Tey, Christiani Jeyakumar Henry
BACKGROUND AND OBJECTIVES: Taste perception plays a key role in consumer acceptance and food choice, which has an important impact on human health. Our aim was to examine the relationship between taste intensities and preferences of sweet (sucrose), salty (sodium chloride and potassium chloride), sour (citric acid), and bitter (quinine and phenylthiocarbamide) in relation to dietary intake and dietary patterns in people of Chinese ancestry. METHODS AND STUDY DESIGN: This cross-sectional study included 100 adult Singaporean Chinese (50 women)...
2018: Asia Pacific Journal of Clinical Nutrition
Parvin Mirmiran, Zahra Bahadoran, Pantea Nazeri, Fereidoun Azizi
OBJECTIVE: There is an interaction between dietary sodium/potassium intake in the pathogenesis of hypertension (HTN) and cardiovascular disease (CVD). The aim of this study was to investigate the association of dietary sodium to potassium (Na/K) ratio and the risk of HTN and CVD in a general population of Iranian adults. METHODS: In this prospective cohort study, adults men and women with complete baseline data were selected from among participants of the Tehran Lipid and Glucose Study and were followed up for 6...
January 30, 2018: Clinical and Experimental Hypertension: CHE
Sriram Ravindran, Kausthubh Ramachandran, Gino A Kurian
Sodium thiosulfate (STS) has shown promising effects in amelioration of myocardial ischemia-reperfusion injury (IR) in a rat model and is clinically useful in the treatment of chronic kidney disease (CKD) associated calciphylaxis. As the prevalence of cardiac complications is higher in CKD, we tested the effectiveness of STS in a rat model of adenine-induced vascular calcification and subjected the heart to IR. We observed an increased infarct size (29%) by TTC staining, lactate dehydrogenase (54%) and creatine kinase (32%) release in the coronary perfusate and altered hemodynamics compared to a normal rat treated with STS and subjected to IR...
January 20, 2018: Biochimie
Ashima K Kant, Barry I Graubard
Restaurant prepared foods are known to be energy-dense and high in fat and sodium, but lower in protective nutrients. There is evidence of higher risk of adiposity, type II diabetes, and heart disease in frequent consumers of restaurant meals. However, the risk of mortality as a long-term health consequence of frequent consumption of restaurant meals has not been examined. We examined the prospective risk of all-cause and coronary heart disease, cerebrovascular disease and diabetes (cardiometabolic) mortality in relation to frequency of eating restaurant prepared meals in a national cohort...
2018: PloS One
Stefan Markus Weiner
Renal involvement is common and heterogenous in connective tissue diseases and has a main influence on prognosis and mortality. In systemic lupus erythematosus proliferative glomerulonephritis is the most common manifestation, while in primary Sjogren's syndrome interstitial nephritis with tubular dysfunction is the predominant pathological feature. In systemic sclerosis the most serious renal manifestation is scleroderma renal crisis characterized by abrupt onset of hypertension and acute kidney injury associated with an increase in plasma renin activity...
January 2018: Deutsche Medizinische Wochenschrift
Owen J Kelly, Jennifer C Gilman, Jasminka Z Ilich
The 2015 US dietary guidelines advise the importance of good dietary patterns for health, which includes all nutrients. Micronutrients are rarely, if ever, consumed separately, they are not tissue specific in their actions and at the molecular level they are multitaskers. Metabolism functions within a seemingly random cellular milieu however ratios are important, for example, the ratio of adenosine triphosphate to adenosine monophosphate, or oxidized to reduced glutathione. Health status is determined by simple ratios, such as the waist hip ratio, or ratio of fat mass to lean mass...
January 19, 2018: Nutrients
Danika Krupp, Jonas Esche, Gert Bernardus Maria Mensink, Stefanie Klenow, Michael Thamm, Thomas Remer
Diets rich in fruits and vegetables, like the Dietary Approaches to Stop Hypertension (DASH)-diet, are usually characterized by high potassium intake and reduced dietary acid load, and have been shown to reduce blood pressure (BP). However, the relevance of potential renal acid load (PRAL) for BP has not been compared with the relevance to BP of urinary biomarker (K-urine)- and dietary food frequency questionnaire (K-FFQ)-based estimates of potassium intake in a general adult population sample. For 6788 participants (aged 18-79 years) of the representative German Health-Interview and Examination Survey for Adults (DEGS1), associations of PRAL, K-urine, and K-FFQ with BP and hypertension prevalence were cross-sectionally examined in multivariable linear and logistic regression models...
January 19, 2018: Nutrients
Xuejiao Liu, Benzhuo Lu
Potassium channels are much more permeable to potassium than sodium ions, although potassium ions are larger and both carry the same positive charge. This puzzle cannot be solved based on the traditional Poisson-Nernst-Planck (PNP) theory of electrodiffusion because the PNP model treats all ions as point charges, does not incorporate ion size information, and therefore cannot discriminate potassium from sodium ions. The PNP model can qualitatively capture some macroscopic properties of certain channel systems such as current-voltage characteristics, conductance rectification, and inverse membrane potential...
December 2017: Physical Review. E
Inês Lança de Morais, Nuno Lunet, Gabriela Albuquerque, Marcello Gelormini, Susana Casal, Albertino Damasceno, Olívia Pinho, Pedro Moreira, Jo Jewell, João Breda, Patrícia Padrão
This cross-sectional study is aimed at assessing sodium (Na) and potassium (K) content and the molar Na:K ratios of the most commonly available ready-to-eat street foods in Tajikistan and Kyrgyzstan. Four different samples of each of these foods were collected and 62 food categories were evaluated through bromatological analysis. Flame photometry was used to quantify sodium and potassium concentrations. The results show that home-made foods can be important sources of sodium. In particular, main dishes and sandwiches, respectively, contain more than 1400 and nearly 1000 mg Na in an average serving and provide approximately 70% and 50% of the maximum daily recommended values...
January 16, 2018: Nutrients
Yujiang Liu, Yuan Yue, Yuguo Yu, Liwei Liu, Lianchun Yu
Action potentials are the information carriers of neural systems. The generation of action potentials involves the cooperative opening and closing of sodium and potassium channels. This process is metabolically expensive because the ions flowing through open channels need to be restored to maintain concentration gradients of these ions. Toxins like tetraethylammonium can block working ion channels, thus affecting the function and energy cost of neurons. In this paper, by computer simulation of the Hodgkin-Huxley neuron model, we studied the effects of channel blocking with toxins on the information transmission and energy efficiency in squid giant axons...
January 11, 2018: Journal of Computational Neuroscience
X Luta, S Hayoz, C Gréa Krause, K Sommerhalder, E Roos, P Strazzullo, S Beer-Borst
BACKGROUND AND AIMS: High sodium (Na) and low potassium (K) intake are associated with hypertension and CVD risk. This study explored the associations of health literacy (HL), food literacy (FL), and salt awareness with salt intake, K intake, and Na/K ratio in a workplace intervention trial in Switzerland. METHODS AND RESULTS: The study acquired baseline data from 141 individuals, mean age 44.6 years. Na and K intake were estimated from a single 24-h urine collection...
November 13, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Xuejun Yin, Bruce Neal, Maoyi Tian, Zhifang Li, Kristina Petersen, Yuichiro Komatsu, Xiangxian Feng, Yangfeng Wu
OBJECTIVE: Measurement of mean population Na and K intakes typically uses laboratory-based assays, which can add significant logistical burden and costs. A valid field-based measurement method would be a significant advance. In the current study, we used 24 h urine samples to compare estimates of Na, K and Na:K ratio based upon assays done using the field-based Horiba twin meter v. laboratory-based methods. DESIGN: The performance of the Horiba twin meter was determined by comparing field-based estimates of mean Na and K against those obtained using laboratory-based methods...
January 8, 2018: Public Health Nutrition
Yume Nohara-Shitama, Hisashi Adachi, Mika Enomoto, Ako Fukami, Eita Kumagai, Sachiko Nakamura, Shoko Kono, Nagisa Morikawa, Erika Nakao, Akiko Sakaue, Tomoko Tsuru, Yoshihiro Fukumoto
BACKGROUND: Few studies have examined the relationship between accurate monitoring of sodium or potassium consumption and mortality. We aimed to investigate the association between 24-hour urinary sodium or potassium excretion and ≈30-year mortality in a Japanese population using 24-hour urine collection. METHODS AND RESULTS: We enrolled a total of 1291 participants, aged 21 to 85 years, who underwent health checkups, including a blood test and 24-hour urine collection...
January 4, 2018: Journal of the American Heart Association
Cheng-Jie Mao, Chong-Ke Zhong, Yong Yang, Ya-Ping Yang, Fen Wang, Jing Chen, Jin-Ru Zhang, Hui-Jun Zhang, Hong Jin, Ling-Li Xu, Juan-Ying Huang, Chun-Feng Liu
Objective: We aim to report and evaluate the associations between serum sodium and chloride and dyskinesia in patients with Parkinson's disease. One hundred and two patients with Parkinson's disease were enrolled in this study. Methods: Patients' serum electrolytes including sodium, calcium, potassium, magnesium, and chloride were measured. Other demographic information was collected, and Unified Parkinson's disease rating scale and Hoehn and Yahr stage scale were also performed...
December 2017: Brain and Behavior
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