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Sodium Potassium ratio

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https://www.readbyqxmd.com/read/28102885/profound-hyponatraemia-in-the-emergency-department-seasonality-and-risk-factors
#1
Tibor Huwyler, Jerome Stirnemann, Nicolas Vuilleumier, Christophe Marti, Sarah Dugas, Pierre-Alexandre Poletti, Francois P Sarasin, Olivier T Rutschmann
AIMS OF THE STUDY: Profound hyponatremia (<125 mmol/l) is frequent in the emergency department. Its incidence appears to increase during hot weather. Our objectives were to investigate seasonal variations in the incidence of profound hyponatraemia and identify its risk factors. METHODS: The incidence of profound hyponatremia among patients admitted to the emergency department of a university hospital was compared between summer and winter periods over two successive years...
January 19, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28089168/the-relationship-between-dietary-intake-and-other-cardiovascular-risk-factors-with-blood-pressure-in-individuals-without-a-history-of-a-cardiovascular-event-evidence-based-study-with-5670-subjects
#2
Mohsen Mazidi, Mohsen Nematy, Ali Reza Heidari-Bakavoli, Zahra Namadchian, Majid Ghayour-Mobarhan, Gordon A Ferns
BACKGROUND AND AIM: Raised blood pressure is a leading cause of morbidity and mortality worldwide; improved nutritional approaches to population-wide prevention are required.We aimed to investigate the relationship between dietary intake and other cardiovascular risk factors with blood pressure in individuals without a history of a cardiovascular event in an Iranian cohort. MATERIAL AND METHOD: A cross-sectional study of 5670 healthy subjects [approximately 40% (n=2179) males and 60% (n=3491) females] was undertaken in a sample from northeastern Iran...
December 9, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28080924/selected-plasma-biochemistry-analytes-of-healthy-captive-sulcata-african-spurred-tortoises-centrochelys-sulcata
#3
David Eshar, Ady Y Gancz, Nili Avni-Magen, Effi Wagshal, Lisa M Pohlman, Mark A Mitchell
The sulcata or African spurred tortoise (Centrochelys sulcata) is a large tortoise species that is commonly kept in zoologic collections and as a pet. The objectives of this study were to establish reference intervals for selected biochemical analytes in clinically healthy captive sulcata tortoises and to evaluate the impact of blood sampling site and sex. Blood samples were collected from 60 tortoises from either the dorsal coccygeal (tail) vein or the subcarapacial venous plexus based on their body size. The packed cell volume and refractometric total solids (TS) were determined...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28039381/estimating-24-h-urinary-sodium-potassium-ratio-from-casual-spot-urinary-sodium-potassium-ratio-the-intersalt-study
#4
Toshiyuki Iwahori, Katsuyuki Miura, Hirotsugu Ueshima, Queenie Chan, Alan R Dyer, Paul Elliott, Jeremiah Stamler
BACKGROUND: Association between casual and 24-h urinary sodium-to-potassium (Na/K) ratio is well recognized, although it has not been validated in diverse demographic groups. Our aim was to assess utility across and within populations of casual urine to estimate 24-h urinary Na/K ratio using data from the INTERSALT Study. METHODS: The INTERSALT Study collected cross-sectional standardized data on casual urinary sodium and potassium and also on timed 24-h urinary sodium and potassium for 10 065 individuals from 52 population samples in 32 countries (1985-87)...
December 30, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28024910/the-effect-of-potassium-supplementation-on-blood-pressure-in-hypertensive-subjects-a-systematic-review-and-meta-analysis
#5
REVIEW
Tommaso Filippini, Federica Violi, Roberto D'Amico, Marco Vinceti
BACKGROUND: Several intervention studies have investigated the relation between potassium intake and blood-pressure, particularly in hypertensive subjects. However, uncertainties still exist about the existence and the amount of such an effect, and about the role of some potential effect-modifiers, including the baseline potassium intake and geographical area. METHODS: We carried out a systematic review of the evidence concerning such relation in hypertensive subjects, performing a meta-analysis and a meta-regression of RCT with selective and validated long-term (≥4weeks) potassium supplementation...
December 21, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28008953/glycosuria-and-renal-outcomes-in-patients-with-nondiabetic-advanced-chronic-kidney-disease
#6
Chi-Chih Hung, Hugo You-Hsien Lin, Jia-Jung Lee, Lee Moay Lim, Yi-Wen Chiu, Heng-Pin Chiang, Shang-Jyh Hwang, Hung-Chun Chen
Sodium glucose cotransporter 2 inhibitors have shown a potential for renoprotection beyond blood glucose lowering. Glycosuria in nondiabetic patients with chronic kidney disease (CKD) is sometimes noted. Whether glycosuria in CKD implies a channelopathy or proximal tubulopathy is not known. The consequence of glycosuria in CKD is also not studied. We performed a cross-sectional study for the association between glycosuria and urine electrolyte excretion in 208 nondiabetic patients. Fractional excretion (FE) of glucose >4% was 3...
December 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28005709/associations-of-socioeconomic-status-with-prevalence-awareness-treatment-and-control-of-hypertension-in-a-general-japanese-population-nippon-data2010
#7
Atsushi Satoh, Hisatomi Arima, Takayoshi Ohkubo, Nobuo Nishi, Nagako Okuda, Ryusuke Ae, Mariko Inoue, Shuji Kurita, Keiko Murakami, Aya Kadota, Akira Fujiyoshi, Kiyomi Sakata, Tomonori Okamura, Hirotsugu Ueshima, Akira Okayama, Katsuyuki Miura
OBJECTIVE: To investigate associations between socioeconomic status (SES) and prevalence, awareness, treatment, and control of hypertension in Japan's general population. METHODS: In 2010, we established a cohort of participants in the National Health and Nutrition Survey of Japan. The cohort included 2623 adults from 300 randomly selected areas across Japan. Using baseline data, four cross-sectional analyses were performed: association of SES with prevalent hypertension in 2623 participants; association of SES with unawareness of hypertension and with no treatment in 1282 hypertensive patients; and association of SES with uncontrolled hypertension in 720 treated hypertensive patients...
February 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28003811/identification-and-characterization-of-a-novel-association-between-dietary-potassium-and-risk-of-crohn-s-disease-and-ulcerative-colitis
#8
Hamed Khalili, Sakshi Malik, Ashwin N Ananthakrishnan, John J Garber, Leslie M Higuchi, Amit Joshi, Joanna Peloquin, James M Richter, Kathleen O Stewart, Gary C Curhan, Amit Awasthi, Vijay Yajnik, Andrew T Chan
BACKGROUND: Recent animal studies have identified that dietary salt intake may modify the risk and progression of autoimmune disorders through modulation of the IL-23/TH17 pathway, which is critical in the pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD). METHODS: We conducted a prospective study of U.S. women enrolled in the Nurses' Health Study (NHS) and NHSII who provided detailed and validated information on diet and lifestyle beginning in 1984 in NHS and 1991 in NHSII...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27966569/dash-dietary-pattern-and-chronic-kidney-disease-in-elderly-korean-adults
#9
H S Lee, K B Lee, Y Y Hyun, Y Chang, S Ryu, Y Choi
BACKGROUND/OBJECTIVES: Dietary patterns are linked to risk and outcomes in chronic kidney disease (CKD). Dietary intake varies by race, region and age. The relationship between a Dietary Approaches to Stop Hypertension (DASH) diet and CKD in elderly Koreans is unclear. SUBJECTS/METHODS: We conducted cross-sectional analyses of 2408 community-dwelling elderly participants from the Korean National Health and Nutrition Examination Survey (2011-2012). DASH dietary patterns for six nutrients (protein, fiber, calcium, potassium, total fat and sodium) were collected by 24 h recall...
December 14, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27935977/the-effects-of-a-community-based-sodium-reduction-program-in-rural-china-a-cluster-randomized-trial
#10
Nicole Li, Lijing L Yan, Wenyi Niu, Chen Yao, Xiangxian Feng, Jianxin Zhang, Jingpu Shi, Yuhong Zhang, Ruijuan Zhang, Zhixin Hao, Hongling Chu, Jing Zhang, Xian Li, Jianhong Pan, Zhifang Li, Jixin Sun, Bo Zhou, Yi Zhao, Yan Yu, Michael Engelgau, Darwin Labarthe, Jixiang Ma, Stephen MacMahon, Paul Elliott, Yangfeng Wu, Bruce Neal
BACKGROUND: Average sodium intake and stroke mortality in northern China are both among the highest in the world. An effective, low-cost strategy to reduce sodium intake in this population is urgently needed. OBJECTIVE: We sought to determine the effects of a community-based sodium reduction program on salt consumption in rural northern China. DESIGN: This study was a cluster-randomized trial done over 18 months in 120 townships (one village from each township) from five provinces...
2016: PloS One
https://www.readbyqxmd.com/read/27924669/effects-of-15%C3%A2-hz-square-wave-magnetic-fields-on-the-voltage-gated-sodium-and-potassium-channels-in-prefrontal-cortex-pyramidal-neurons
#11
Yu Zheng, Jun-Rong Dou, Yang Gao, Lei Dong, Gang Li
PURPOSE: Although magnetic fields have significant effects on neurons, little is known about the mechanisms behind their effects. The present study aimed to measure the effects of magnetic fields on ion channels in cortical pyramidal neurons. MATERIALS AND METHODS: Cortical pyramidal neurons of Kunming mice were isolated and then subjected to 15 Hz, 1 mT square wave (duty ratio 50%) magnetic fields stimulation. Sodium currents (INa), transient potassium currents (IA) and delayed rectifier potassium currents (IK) were recorded by whole-cell patch clamp method...
December 7, 2016: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/27909561/korean-solar-salts-reduce-obesity-and-alter-its-related-markers-in-diet-induced-obese-mice
#12
Jaehyun Ju, Jia-Le Song, Eui-Seong Park, Myoung-Sool Do, Kun-Young Park
BACKGROUND/OBJECTIVES: The aim of this experiments was to show anti-obesity effects of Korean solar salt from different salt fields in diet-induced obese mice. SUBJECTS/METHODS: Diet-induced obesity (DIO) was induced by a high-fat diet (HFD; 45% cal from fat) in C57BL/6J mice for eight weeks. The mice were fed with the designated diets (chow diet for Normal, HFD for Control, 0.47%-salt-mixed HFD for purified salt (PS), Guerande solar salt from France (SS-G), solar salt from Y salt field (SS-Y), solar salts from T salt field (SS-T) and S salt field (SS-S)) for another eight weeks...
December 2016: Nutrition Research and Practice
https://www.readbyqxmd.com/read/27908408/protective-effect-of-magnesium-acetyltaurate-against-nmda-induced-retinal-damage-involves-restoration-of-minerals-and-trace-elements-homeostasis
#13
Azliana Jusnida Ahmad Jafri, Natasha Najwa Nor Arfuzir, Lidawani Lambuk, Igor Iezhitsa, Renu Agarwal, Puneet Agarwal, Norhafiza Razali, Anna Krasilnikova, Maria Kharitonova, Vasily Demidov, Evgeny Serebryansky, Anatoly Skalny, Alexander Spasov, Ahmad Pauzi Md Yusof, Nafeeza Mohd Ismail
Glutamate-mediated excitotoxicity involving N-methyl-d-aspartate (NMDA) receptors has been recognized as a final common outcome in pathological conditions involving death of retinal ganglion cells (RGCs). Overstimulation of NMDA receptors results in influx of calcium (Ca) and sodium (Na) ions and efflux of potassium (K). NMDA receptors are blocked by magnesium (Mg). Such changes due to NMDA overstimulation are also associated with not only the altered levels of minerals but also that of trace elements and redox status...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27904038/a-retrospective-analysis-of-risk-factors-for-linezolid-associated-hyponatremia-in-japanese-patients
#14
Ryota Tanaka, Yosuke Suzuki, Yukie Takumi, Motoshi Iwao, Yuhki Sato, Kazuhiko Hashinaga, Kazufumi Hiramatsu, Jun-Ichi Kadota, Hiroki Itoh
Linezolid is an oxazolidinone antibiotic against Gram-positive bacteria. Although thrombocytopenia is a major adverse effect of linezolid, hyponatremia also often develops after linezolid administration. This study examined the frequency of hyponatremia that developed during linezolid treatment and identified its risk factors. In this retrospective, single-center, observational cohort study, 61 hospitalized patients treated with linezolid between January 2013 and January 2015 were analyzed. Hyponatremia was defined as a sodium level of ≤134 mEq/L for the duration of linezolid treatment...
2016: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/27896362/the-association-between-urinary-sodium-to-potassium-ratio-and-bone-density-in-middle-aged-chinese-adults
#15
W T Cao, J He, G D Chen, C Wang, R Qiu, Y M Chen
: The joint effect of sodium and potassium on bone health remains uncertain. We examined the associations between urinary excretion of sodium, potassium, and their ratio and bone mineral density (BMD), and reported an inverse association between urinary sodium-to-potassium ratio and BMD in women, but not in men. INTRODUCTION: Several studies have suggested that a higher sodium or lower potassium intake is associated with poor bone health. However, few studies have examined their joint effects...
November 28, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27881853/relationship-between-24-h-urine-sodium-potassium-ratio-and-central-aortic-systolic-blood-pressure-in-hypertensive-patients
#16
Moo-Yong Rhee, Sung-Joon Shin, Namyi Gu, Deuk-Young Nah, Byong-Kyu Kim, Kyung-Soon Hong, Eun-Joo Cho, Ki-Chul Sung, Sim-Yeol Lee, Kwang-Il Kim
Studies evaluating the relationship between measured 24-h urine sodium (24HUNa), potassium (24HUK) and aortic blood pressure (BP) are rare, and no such study has been performed with an Asian population. We evaluated the relationship between 24HUNa, 24HUK, casual BP, 24-h ambulatory BP and aortic BP by analyzing data from 524 participants with valid 24-h urine collection, 24-h ambulatory BP and central BP measurements (mean age 48.1±9.8 years, 193 men). Hypertension was defined as a 24-h ambulatory BP ⩾130/80 mm Hg or current treatment for hypertension (n=219)...
November 24, 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/27871690/the-relation-between-breast-milk-sodium-to-potassium-ratio-and-maternal-report-of-a-milk-supply-concern
#17
Masahiko Murase, Erin A Wagner, Caroline J Chantry, Kathryn G Dewey, Laurie A Nommsen-Rivers
We report that, among exclusively breastfeeding mothers at day 7 postpartum, those with milk supply concerns were significantly more likely to exhibit biochemical evidence of less progress toward mature lactation (elevated ratio of breast milk sodium to potassium concentration). Furthermore, an elevated ratio of breast milk sodium to potassium concentration was predictive of early weaning.
November 18, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27836340/short-term-low-severity-spring-grassland-fire-impacts-on-soil-extractable-elements-and-soil-ratios-in-lithuania
#18
Paulo Pereira, Artemi Cerda, Deborah Martin, Xavier Úbeda, Daniel Depellegrin, Agata Novara, Juan F Martínez-Murillo, Eric C Brevik, Oleksandr Menshov, Jesus Rodrigo Comino, Jessica Miesel
Spring grassland fires are common in boreal areas as a consequence of slash and burn agriculture used to remove dry grass to increase soil nutrient properties and crop production. However, few works have investigated fire impacts on these grassland ecosystems, especially in the immediate period after the fire. The objective of this work was to study the short-term impacts of a spring grassland fire in Lithuania. Four days after the fire we established a 400m(2) sampling grid within the burned area and in an adjacent unburned area with the same topographical, hydrological and pedological characteristics...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27835849/nitric-oxide-signaling-is-involved-in-the-response-to-iron-deficiency-in-the-woody-plant-malus-xiaojinensis
#19
Longmei Zhai, Dashuang Xiao, Chaohua Sun, Ting Wu, Zhenhai Han, Xinzhong Zhang, Xuefeng Xu, Yi Wang
To cope with iron (Fe) deficiency, plants have evolved a wide range of adaptive responses from changes in morphology to altered physiological responses. Recent studies have demonstrated that nitric oxide (NO) is involved in the Fe-deficiency response through hormonal signaling pathways. Here, we report that NO plays a significant role in Malus xiaojinensis, an Fe-efficient woody plant. Fe deficiency triggered significant accumulation of NO in the root system, predominantly in the outer cortical and epidermal cells of the elongation zone...
December 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27805727/reference-intervals-for-biochemical-blood-variables-packed-cell-volume-and-body-temperature-in-pet-rats-rattus-norvegicus-using-point-of-care-testing
#20
Anneleen Houtmeyers, Luc Duchateau, Bettina Grünewald, Katleen Hermans
BACKGROUND: Rats (Rattus norvegicus) are increasingly kept as pets, thus more and more requiring veterinary care. Important differences exist between pet and laboratory rats, but little information is available on pet rats. Diagnosis and treatment of pet rat diseases would benefit from RIs specific for this animal population. OBJECTIVES: The aim was to establish RIs for biochemical blood variables, PCV, and body temperature in pet rats. Additionally, influences of sex and feed rationing method (ad libitum, restricted) on these variables were determined...
December 2016: Veterinary Clinical Pathology
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