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https://www.readbyqxmd.com/read/28721101/survey-of-malaria-and-anti-dengue-virus-igg-among-febrile-hiv-infected-patients-attending-a-tertiary-hospital-in-abuja-nigeria
#1
Jelili Olaide Mustapha, Anthony Uchenna Emeribe, Idris Abdullahi Nasir
BACKGROUND: Dengue and malaria are infections, of great public health concern, especially in sub-Saharan Africa where the burden of HIV infection is high. This study was conducted to determine the seroprevalence of dengue virus IgG antibodies and dengue/malaria coinfection among febrile HIV-infected patients attending the University of Abuja Teaching Hospital, Gwagwalada, Abuja. METHODS: In this cross-sectional study, blood samples from 178 consenting HIV-infected patients receiving antiretroviral therapy were collected and tested for plasmodiasis and anti-Dengue virus IgG using malaria microscopy and ELISA, respectively...
2017: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/28719659/dengue-prediction-by-the-web-tweets-are-a-useful-tool-for-estimating-and-forecasting-dengue-at-country-and-city-level
#2
Cecilia de Almeida Marques-Toledo, Carolin Marlen Degener, Livia Vinhal, Giovanini Coelho, Wagner Meira, Claudia Torres Codeço, Mauro Martins Teixeira
BACKGROUND: Infectious diseases are a leading threat to public health. Accurate and timely monitoring of disease risk and progress can reduce their impact. Mentioning a disease in social networks is correlated with physician visits by patients, and can be used to estimate disease activity. Dengue is the fastest growing mosquito-borne viral disease, with an estimated annual incidence of 390 million infections, of which 96 million manifest clinically. Dengue burden is likely to increase in the future owing to trends toward increased urbanization, scarce water supplies and, possibly, environmental change...
July 18, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28719400/dengue-vaccines-implications-for-dengue-control
#3
Matthew L Robinson, Anna P Durbin
PURPOSE OF REVIEW: Dengue, the most common arbovirus, is an increasingly significant cause of morbidity worldwide. After decades of research, an approved tetravalent dengue vaccine is finally available. Models constructed using recently available vaccine efficacy data allow for a data-driven discussion of the potential impact of dengue vaccine deployment on global control. RECENT FINDINGS: Phase 3 efficacy trials demonstrated that the approved dengue vaccine, chimeric yellow fever-dengue-tetravalent dengue vaccine, has an efficacy of 60% against dengue illness of any severity...
July 14, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28719315/analysis-of-clinical-and-laboratory-alterations-related-to-dengue-case-severity-comparison-between-serotypes-2-and-4-in-brazil
#4
Nieli Rodrigues da Costa Faria, Victor Edgar Fiestas Solorzano, Luiz José de Souza, Rita Maria Ribeiro Nogueira, Fernanda de Bruycker-Nogueira, Thaís Chouin-Carneiro, Jaqueline Bastos Santos Simões, Monique da Rocha Queiroz Lima, Luzia Maria de Oliveira Pinto, Claire Fernandes Kubelka, Manoela Heringer, Elzinandes Leal de Azeredo, Flavia Barreto Dos Santos
The increase in severe dengue (SD) cases has caused great impact on public health and has concerned authorities of countries where the disease is endemic and epidemics reach high proportions. The recognition of progression signs of this severe disease during the initial febrile phase can be difficult, since the symptoms are often indistinguishable from other febrile diseases. The aim of this study was to evaluate the clinical manifestations and laboratory findings in patients from two dengue outbreaks and their association with the disease...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719300/chikungunya-and-zika-virus-cases-detected-against-a-backdrop-of-endemic-dengue-transmission-in-vietnam
#5
Nguyen Than Ha Quyen, Duong Thi Hue Kien, Maia Rabaa, Nguyen Minh Tuan, Tran Thuy Vi, Le Van Tan, Nguyen Thanh Hung, Ha Manh Tuan, Ta Van Tram, Nguyen Le Da Ha, Han Khoi Quang, Nguyen Quoc Doanh, Nguyen Van Vinh Chau, Bridget Wills, Cameron P Simmons
Between 2010 and 2014, four chikungunya and two Zika virus infections were identified among 8,105 febrile children in southern Vietnam. Zika viruses were linked to French Polynesian strains, chikungunya to Cambodian strains. Against a backdrop of endemic dengue transmission, chikungunya and Zika present an additional arboviral disease burden in Vietnam.
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717366/interrelationship-between-climatic-ecologic-social-and-cultural-determinants-affecting-dengue-emergence-and-transmission-in-puerto-rico-and-their-implications-for-zika-response
#6
REVIEW
Angela Matysiak, Amira Roess
OBJECTIVE: The global resurgence of dengue has been attributed to rapid population growth, urban expansion, increased air travel, globalization, and climate change. Dengue is now endemic in Puerto Rico. Puerto Rico is at risk for Zika, another emerging arbovirus. The interrelationship between climatic, ecological, social, and cultural factors that affect dengue and other arboviruses' transmission is understudied. DESIGN: The objective of this systematic review is to examine the interrelationship between climatic, ecological, social, and cultural factors on dengue transmission in Puerto Rico and to draw lessons for Zika response...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28699542/community-cost-benefit-discussions-that-launched-the-camino-verde-intervention-in-nicaragua
#7
Carlos Hernandez-Alvarez, Jorge Arosteguí, Harold Suazo-Laguna, Rosa Maria Reyes, Josefina Coloma, Eva Harris, Neil Andersson, Robert J Ledogar
BACKGROUND: Recent literature on community intervention research stresses system change as a condition for durable impact. This involves highly participatory social processes leading to behavioural change. METHODS: Before launching the intervention in the Nicaraguan arm of Camino Verde, a cluster-randomised controlled trial to show that pesticide-free community mobilisation adds effectiveness to conventional dengue controls, we held structured discussions with leaders of intervention communities on costs of dengue illness and dengue control measures taken by both government and households...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28698348/determinants-of-mortality-and-prolonged-hospital-stay-among-dengue-patients-attending-tertiary-care-hospital-a-cross-sectional-retrospective-analysis
#8
Tauqeer Hussain Mallhi, Amer Hayat Khan, Azmi Sarriff, Azreen Syazril Adnan, Yusra Habib Khan
OBJECTIVES: Dengue imposes substantial economic, societal and personal burden in terms of hospital stay, morbidity and mortality. Early identification of dengue cases with high propensity of increased hospital stay and death could be of value in isolating patients in need of early interventions. The current study was aimed to determine the significant factors associated with dengue-related prolonged hospitalisation and death. DESIGN: Cross-sectional retrospective study...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28683119/the-socio-economic-burden-of-snakebite-in-sri-lanka
#9
Anuradhani Kasturiratne, Arunasalam Pathmeswaran, A Rajitha Wickremasinghe, Shaluka F Jayamanne, Andrew Dawson, Geoff K Isbister, Hithanadura Janaka de Silva, David G Lalloo
BACKGROUND: Snakebite is a major problem affecting the rural poor in many of the poorest countries in the tropics. However, the scale of the socio-economic burden has rarely been studied. We undertook a comprehensive assessment of the burden in Sri Lanka. METHODS: Data from a representative nation-wide community based household survey were used to estimate the number of bites and deaths nationally, and household and out of pocket costs were derived from household questionnaires...
July 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28662144/seroprevalence-of-antibodies-to-dengue-and-chikungunya-viruses-in-thailand
#10
Sompong Vongpunsawad, Duangnapa Intharasongkroh, Thanunrat Thongmee, Yong Poovorawan
The abundance of Aedes mosquito species enabled widespread transmission of mosquito-borne chikungunya virus (CHIKV) and dengue virus (DENV) in Southeast Asia. Periodic seroprevalence surveys are therefore necessary to assess the viral burden in the population and the effectiveness of public health interventions. Since the current seroprevalence for CHIKV and DENV in Thailand are unknown, we evaluated evidence of past infection among Thais. Eight-hundred and thirty-five serum samples obtained from individuals living in central and southern Thailand were assessed for anti-CHIKV and anti-DENV IgG antibodies using commercial enzyme-linked immunosorbent assays...
2017: PloS One
https://www.readbyqxmd.com/read/28658384/increase-in-the-burden-of-dengue-in-brazil-and-federated-units-2000-and-2015-analysis-of-the-global-burden-of-disease-study-2015
#11
Valdelaine Etelvina Miranda de Araújo, Juliana Maria Trindade Bezerra, Frederico Figueiredo Amâncio, Valéria Maria de Azeredo Passos, Mariângela Carneiro
Objective: To describe the main metrics on dengue generated by Global Burden of Disease (GBD) Study 2015, for Brazil and its 27 federated units, in the years 2000 and 2015. Methods: The metrics described were: incidence and mortality rates by dengue, standardized by age, years of life lost (YLL), years lived with disability (YLD), and disability-adjusted life years (DALY) (in absolute frequency and age-standardized rates). The estimated metrics were presented with uncertainty intervals (UI 95%) for the years 2000 and 2015, accompanied by the relative percentages of changes...
May 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/28636445/developing-a-casper-survey-to-assess-the-prevalence-of-risk-factors-for-neglected-tropical-diseases-in-texas
#12
Seth Smitherman, Tracy Hammond, Daniel Goldberg, Jennifer Horney
While more than a billion people live at risk of neglected tropical diseases in areas of Asia, sub-Saharan Africa, and Latin America, the degree to which such diseases burden countries like the United States is currently unclear. Even though many neglected tropical diseases such as dengue, leishmaniasis, and Chagas disease are not endemic to the United States, the possibility of their emergence is noteworthy, especially in states like Texas, which has high levels of poverty, a large immigrant population, and a climate amenable to the vectors for these diseases and is geographically proximate to endemic areas...
May 2017: Health Security
https://www.readbyqxmd.com/read/28632829/-advances-in-dengue-virus-research-in-colombia-the-role-of-cellular-micrornas-as-an-anti-dengue-virus-response
#13
Juan Camilo Castrillón-Betancur, Silvio Urcuqui-Inchima
Dengue is one of the most important mosquito-borne diseases, and its incidence has increased at an alarming rate in recent years, becoming a real public health problem. Currently, there is no vaccine or medication or proper treatment for dengue control. Considering this situation, it is necessary to prioritize the search for new alternatives and strategies for dengue prevention and control, in order to reduce not only the economic burden of endemic countries, but also to improve the quality of life of patients...
April 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28619082/assessing-changes-in-knowledge-attitude-and-practices-on-dengue-diagnosis-and-management-among-primary-care-physicians-after-the-largest-dengue-epidemic-in-singapore
#14
Junxiong Pang, Zoe Jane-Lara Hildon, Tun Linn Thein, Jing Jin, Yee Sin Leo
BACKGROUND: Dengue results in high morbidity and mortality globally. The knowledge, attitude and practices (KAP) of dengue management, including diagnosis, among primary care physicians (PCPs) are important to reduce dengue transmission and burden. However, there is a lack of understanding on the impact of dengue epidemic on dengue management. Hence, the aim of this study is to examine the changes in KAP on dengue management among PCPs before and after the largest dengue epidemic in 2013 in Singapore...
June 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28617803/dengue-seroprevalence-and-force-of-primary-infection-in-a-representative-population-of-urban-dwelling-indonesian-children
#15
Ari Prayitno, Anne-Frieda Taurel, Joshua Nealon, Hindra Irawan Satari, Mulya Rahma Karyanti, Rini Sekartini, Soedjatmiko Soedjatmiko, Hartono Gunardi, Bernie Endyarni Medise, R Tedjo Sasmono, James Mark Simmerman, Alain Bouckenooghe, Sri Rezeki Hadinegoro
BACKGROUND: Indonesia reports the second highest dengue disease burden in the world; these data are from passive surveillance reports and are likely to be significant underestimates. Age-stratified seroprevalence data are relatively unbiased indicators of past exposure and allow understanding of transmission dynamics. METHODOLOGY/PRINCIPAL FINDINGS: To better understand dengue infection history and associated risk factors in Indonesia, a representative population-based cross-sectional dengue seroprevalence study was conducted in 1-18-year-old urban children...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28598047/awareness-and-outcome-of-changing-trends-in-clinical-profile-of-dengue-fever-a-retrospective-analysis-of-dengue-epidemic-from-january-to-december-2014-at-a-tertiary-care-hospital
#16
Jitendra Singh, Anju Dinkar, Virendra Atam, D Himanshu, Kamlesh Kumar Gupta, Kauser Usman, Ravi Misra
BACKGROUND: Dengue fever is caused by mosquito-borne arboviral infection that has become a public health concern globally. Recently, an alarming rise of dengue has also been seen in India. Hence the study was undertaken to know profile of clinical manifestations and laboratory findings during the evolution of dengue fever. METHODS: In this study, retrospective data analysis was done in 216 seropositive dengue patients admitted between January to December 2014 in department of medicine at a north Indian care hospital...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28590795/a-recombinant-live-attenuated-tetravalent-vaccine-for-the-prevention-of-dengue
#17
Bruno Guy, Fernando Noriega, R Leon Ochiai, Maïna L'azou, Valentine Delore, Anna Skipetrova, François Verdier, Laurent Coudeville, Stephen Savarino, Nicholas Jackson
Dengue is an important and still growing public health problem associated with substantial morbidity, as well as significant social and economic impact. The present review describes the main features and development of the first dengue vaccine (CYD-TDV, Dengvaxia®), which has been licensed by several dengue-endemic countries in Asia and Latin America for use in populations above 9 years of age. Areas covered: The review focuses on the large clinical development of CYD-TDV, which includes in particular two pivotal phase III efficacy trials conducted in Asia and Latin America and supported vaccine licensure...
July 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28579763/trends-of-dengue-disease-epidemiology
#18
REVIEW
Cucunawangsih, Nata Pratama Hardjo Lugito
Dengue disease is an emerging mosquito-borne viral infection transmitted between humans by Aedes spp. that are distributed mainly in the tropical and subtropical region along with chikungunya and zika diseases. The distribution of dengue disease is influenced by local variation, such as geography, rainfall, temperature, and rapid urbanization or migration. The epidemy of mosquito-borne infection significantly led to increased number of cases and hyperendemicity which induce a more severe form of dengue accompanied by cocirculation of chikungunya and zika...
2017: Virology: Research and Treatment
https://www.readbyqxmd.com/read/28577343/de-novo-rna-synthesis-catalyzed-by-the-zika-virus-rna-polymerase-domain
#19
Christina Calmels, Michel Ventura, Cindy Aknin, Mathieu Métifiot, Marie-Line Andreola
Mosquito- and tick-borne pathogens including Chikungunya, Dengue, Japanese encephalitis, West Nile, Yellow fever and Zika virus, represent a new economic and public health challenge. In the absence of effective vaccines and specific therapies, only supportive regimens are administrated for most of these infections. Thus, the development of a targeted therapy is mandatory to stop the rapid progression of these pathogens and preoccupant associated burdens such as Guillain-Barre syndrome, microcephaly. For this, it is essential to develop biochemical tools to help study and target key viral enzymes involved in replication such as helicase complexes, methyl-transferases and RNA-dependent RNA polymerases...
June 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28560654/newer-vaccines-against-mosquito-borne-diseases
#20
Anju Aggarwal, Neha Garg
Mosquitos are responsible for a number of protozoal and viral diseases. Malaria, dengue, Japanese encephalitis (JE) and chikungunya epidemics occur commonly all over the world, leading to marked mortality and morbidity in children. Zika, Yellow fever and West Nile fever are others requiring prevention. Environmental control and mosquito bite prevention are useful in decreasing the burden of disease but vaccination has been found to be most cost-effective and is the need of the hour. RTS,S/AS01 vaccine is the first malaria vaccine being licensed for use against P...
May 31, 2017: Indian Journal of Pediatrics
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