Zurui Liu, Juan Dai, Ruijia Liu, Ziyi Shen, Ai Huang, YuKun Huang, Lijun Wang, Pengfei Chen, Zheng Zhou, Hang Xiao, Xianggui Chen, Xiao Yang
BACKGROUND: Obesity has been demonstrated as a risk factor that seriously affects health. Insoluble dietary fiber, as a major component of dietary fiber (DF), has positive effects on obesity, inflammation and diabetes. RESULTS: In this study, complex insoluble DF (IDF) was prepared using 50% enoki mushroom IDF, 40% carrot IDF, and 10% oat IDF. The effects and potential mechanism of complex IDF on obesity were investigated in C57BL/6 mice fed a high-fat diet. The results showed that feeding diets containing 5% complex IDF for 8 weeks significantly reduced mouse body weight, epididymal lipid index, ectopic fat deposition, and improved mouse liver lipotoxicity (reduced serum levels of alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase), fatty liver, and short-chain fatty acid composition...
February 13, 2024: Journal of the Science of Food and Agriculture