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https://www.readbyqxmd.com/read/28531988/optimization-of-toxic-biological-compound-adsorption-from-aqueous-solution-onto-silicon-and-silicon-carbide-nanoparticles-through-response-surface-methodology
#1
Vinod Kumar Gupta, Ali Fakhri, Sahar Rashidi, Ahmed A Ibrahim, Mohammad Asif, Shilpi Agarwal
The subject of this paper is removal of Aflatoxin B1 as toxic biological compound adsorption onto Silicon (Si) and Silicon carbide (SiC) nanoparticles in aqueous matrices using Response surface methodology. The surface frame of Si and SiC nanoparticles were comminuted by XRD, TEM, SEM, and BET. Experiments were steered well-found by Box-Behnken plan (BBD). Experiments of batch method were performed to prognosticate the reaction equilibrium of Aflatoxin B1 removal. The response surface methodological approach was used...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531962/how-geostatistics-can-help-you-find-lead-and-galvanized-water-service-lines-the-case-of-flint-mi
#2
Pierre Goovaerts
In the aftermath of Flint drinking water crisis, most US cities have been scrambling to locate all lead service lines (LSLs) in their water supply systems. This information, which is most often inaccurate or lacking, is critical to assess compliance with the Lead and Copper Rule and to plan the replacement of lead and galvanized service lines (GSLs) as currently under way in Flint. This paper presents the first geospatial approach to predict the likelihood that a home has a LSL or GSL based on neighboring field data (i...
May 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28531951/identifying-and-quantifying-geochemical-and-mixing-processes-in-the-matanza-riachuelo-aquifer-system-argentina
#3
S Armengol, M Manzano, S A Bea, S Martínez
The Matanza-Riachuelo River Basin, in the Northeast of the Buenos Aires Province, is one of the most industrialized and populated region in Argentina and it is worldwide known for its alarming environmental degradation. In order to prevent further damages, the aquifer system, which consists of two overlaid aquifers, is being monitored from 2008 by the river basin authority, Autoridad de la Cuenca Matanza-Riachuelo. The groundwater chemical baseline has been established in a previous paper (Zabala et al., 2016), and this one is devoted to the identification of the main physical and hydrogeochemical processes that control groundwater chemistry and its areal distribution...
May 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28531901/a-comparison-between-intermittent-peritoneal-dialysis-and-automatic-peritoneal-dialysis-on-urgent-peritoneal-dialysis
#4
Chang Wang, Xiao Fu, Yuan Yang, Jun Deng, Hong-Qing Zhang, Hong-Mei Deng, Jia Lu, Youming Peng, Hong Liu, Fu-You Liu, Yinghong Liu
BACKGROUND: Urgent-start dialysis is a major problem for incident dialysis population. Urgent start on hemodialysis is associated with an increased risk of infectious or mechanical complications, and its mortality is equal to or higher than that of urgent start on peritoneal dialysis (PD). However, compared to patients starting PD in a planned setting, those on urgent-started PD have an increased risk of mechanical complications and lower technique survival. METHODS: In this study, 101 adult incident dialysis patients (≥18 years old) who underwent Tenckhoff catheter implantation were enrolled...
May 23, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28531829/prevalence-of-gestational-diabetes-mellitus-in-europe-a-meta-analysis
#5
Claire E Eades, Dawn M Cameron, Josie M M Evans
AIMS: Estimates of the prevalence of gestational diabetes vary widely. It is important to have a clear understanding of the prevalence of this condition to be able to plan interventions and health care provision. This paper describes a meta-analysis of primary research data reporting the prevalence of gestational diabetes mellitus in the general pregnant population of developed countries in Europe. METHODS: Four electronic databases were systematically searched in May 2016...
May 9, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28531788/association-of-dietary-factors-with-severity-of-coronary-artery-disease
#6
Namita Mahalle, M K Garg, S S Naik, M V Kulkarni
BACKGROUND: Cardiovascular disease has taken epidemic proportions during past decades. Cardiovascular risk factors contribute to progression of coronary lesions, worsening the patient's prognosis. This study was planned to analyze the association of dietary factors with severity of coronary artery disease (CAD) in Indian patients. METHODS: Three hundred patients with known coronary disease above the age of 25 years were included in this study. Blood samples were collected for biochemical markers...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531561/a-meta-analysis-of-neurocognition-in-youth-with-familial-high-risk-for-bipolar-disorder
#7
E Bora, A Özerdem
OBJECTIVE: Neuropsychological impairment, including deficits in social cognition is evident in subjects at genetic high-risk for psychosis. However, findings in youth at genetic risk to bipolar disorder (BP) have been suggested to be less supportive of premorbid deficits. We aimed to conduct a meta-analysis of cognitive deficits in youth with familiar risk for bipolar disorder (FHR-BD). METHODS: A novel meta-analysis of FHR-BD (mean age 10-25), including 18 studies (786 offsprings/siblings of patients with BD and 794 healthy controls), was conducted...
March 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28531270/utilization-of-quantitative-susceptibility-mapping-for-direct-targeting-of-the-subthalamic-nucleus-during-deep-brain-stimulation-surgery
#8
Jonathan Rasouli, Ritesh Ramdhani, Fedor E Panov, Alexey Dimov, Yan Zhang, Catherine Cho, Yi Wang, Brian Harris Kopell
BACKGROUND: Deep brain stimulation of the subthalamic nucleus (STN) has demonstrated efficacy in improving motor disability in Parkinson's disease. The recently developed quantitative susceptibility mapping (QSM) technique, which can accurately map iron deposits in deep brain nuclei, promises precise targeting of the STN. OBJECTIVE: To demonstrate the use of QSM to target STN effectively by correlating with classical physiological-based targeting measures in a prospective study...
May 21, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28531226/intercenter-validation-of-a-knowledge-based-model-for-automated-planning-of-volumetric-modulated-arc-therapy-for-prostate-cancer-the-experience-of-the-german-rapidplan-consortium
#9
Carolin Schubert, Oliver Waletzko, Christian Weiss, Dirk Voelzke, Sevda Toperim, Arnd Roeser, Silvia Puccini, Marc Piroth, Christian Mehrens, Jan-Dirk Kueter, Kirsten Hierholz, Karsten Gerull, Antonella Fogliata, Andreas Block, Luca Cozzi
PURPOSE: To evaluate the performance of a model-based optimisation process for volumetric modulated arc therapy applied to prostate cancer in a multicentric cooperative group. The RapidPlan (RP) knowledge-based engine was tested for the planning of Volumetric modulated arc therapy with RapidArc on prostate cancer patients. The study was conducted in the frame of the German RapidPlan Consortium (GRC). METHODS AND MATERIALS: 43 patients from one institute of the GRC were used to build and train a RP model...
2017: PloS One
https://www.readbyqxmd.com/read/28531198/a-real-time-traffic-control-method-for-the-intersection-with-pre-signals-under-the-phase-swap-sorting-strategy
#10
Yiming Bie, Zhiyuan Liu, Yinhai Wang
To deal with the conflicts between left-turn and through traffic streams and increase the discharge capacity, this paper addresses the pre-signal which is implemented at a signalized intersection. Such an intersection with pre-signal is termed as a tandem intersection. For the tandem intersection, phase swap sorting strategy is deemed as the most effective phasing scheme in view of some exclusive merits, such as easier compliance of drivers, and shorter sorting area. However, a major limitation of the phase swap sorting strategy is not considered in previous studies: if one or more vehicle is left at the sorting area after the signal light turns to red, the capacity of the approach would be dramatically dropped...
2017: PloS One
https://www.readbyqxmd.com/read/28531088/influence-of-patient-mispositioning-on-sar-distribution-and-simulated-temperature-in-regional-deep-hyperthermia
#11
Bassim Aklan, Pia Gierse, Josefin Hartmann, Oliver J Ott, Rainer Fietkau, Christoph Bert
Patient positioning plays an important role in regional deep hyperthermia to obtain a successful hyperthermia treatment. In this study, the influence of possible patient mispositioning was systematically assessed on specific absorption rate (SAR) and temperature distribution. With a finite difference time domain approach, the SAR and temperature distributions were predicted for six patients at 312 positions. Patient displacements and rotations as well as the combination of both were considered inside the Sigma-Eye applicator...
May 22, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28530533/respiratory-motion-management-in-pet-ct-applications-and-clinical-usefulness
#12
Luca Guerra, Elena De Ponti, Sabrina Morzenti, Chiara Spadavecchia, Cinzia Crivellaro
Although breathing movement can introduce heavy bias in both image quality and quantitation, currently there is lack of interest for the respiratory motion management in PET/CT imaging. The respiratory gating technology has shown significant benefits on image quality, reducing motion related artifacts and increasing quantification. Indeed, many papers have demonstrated that there is a consistent increase of the Standardized Uptake Value (SUV) in gated PET images when compared to ungated ones, particularly for the small lesions located both in liver and in lung...
May 19, 2017: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/28530527/health-care-costs-associated-with-addition-titration-and-switching-antihypertensive-medications-after-first-line-treatment-results-from-a-commercially-insured-sample
#13
Kalyani B Sonawane Deshmukh, Jingjing Qian, Kimberly B Garza, Bradley M Wright, Peng Zeng, Cecilia M Ganduglia Cazaban, Richard A Hansen
BACKGROUND: Treatment modifications are necessary for addressing issues related to efficacy and tolerance of first-line monotherapy, but they increase the economic burden on patients and their health plans. Understanding the differences in costs between alternative treatment modification strategies, if any, can serve as a guideline for clinical decision making and for designing cost-containment strategies. OBJECTIVE: To compare the health care utilization costs between (a) addition (i...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28530524/is-real-world-evidence-used-in-p-t-monographs-and-therapeutic-class-reviews
#14
Jason T Hurwitz, Mary Brown, Jennifer S Graff, Loretta Peters, Daniel C Malone
BACKGROUND: Payers are faced with making coverage and reimbursement decisions based on the best available evidence. Often these decisions apply to patient populations, provider networks, and care settings not typically studied in clinical trials. Treatment effectiveness evidence is increasingly available from electronic health records, registries, and administrative claims. However, little is known about when and what types of real-world evidence (RWE) studies inform pharmacy and therapeutic (P&T) committee decisions...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28530521/the-direct-cost-of-managing-a-rare-disease-assessing-medical-and-pharmacy-costs-associated-with-duchenne-muscular-dystrophy-in-the-united-states
#15
Sarah Thayer, Christopher Bell, Craig M McDonald
BACKGROUND: A Duchenne muscular dystrophy (DMD) cohort was identified using a claims-based algorithm to estimate health care utilization and costs for commercially insured DMD patients in the United States. Previous analyses have used broad diagnosis codes that include a range of muscular dystrophy types as a proxy to estimate the burden of DMD. OBJECTIVE: To estimate DMD-associated resource utilization and costs in a sample of patients identified via a claims-based algorithm using diagnosis codes, pharmacy prescriptions, and procedure codes unique to DMD management based on DMD clinical milestones...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28530519/does-a-one-size-fits-all-cost-sharing-approach-incentivize-appropriate-medication-use-a-roundtable-on-the-fairness-and-ethics-associated-with-variable-cost-sharing
#16
Jennifer S Graff, Chuck Shih, Thomas Barker, Gabriela Dieguez, Cheryl Larson, Helen Sherman, Robert W Dubois
BACKGROUND: Tiered formularies, in which patients pay copays or coinsurance out-of-pocket (OOP), are used to manage costs and encourage more efficient health care resource use. Formulary tiers are typically based on the cost of treatment rather than the medical appropriateness for the patient. Cost sharing may have unintended consequences on treatment adherence and health outcomes. Use of higher-cost, higher-tier medications can be due to a variety of factors, including unsuccessful treatment because of lack of efficacy or side effects, patient clinical or genetic characteristics, patient preferences to avoid potential side effects, or patient preferences based on the route of administration...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28530507/the-reliability-and-sensitivity-of-performance-measures-in-a-novel-pace-bowling-test
#17
Simon A Feros, Warren B Young, Brendan J O'Brien
OBJECTIVES: Evaluate the reliability and sensitivity of performance measures in a novel pace bowling test. METHODS: Thirteen male amateur club fast bowlers completed a novel pace bowling test on two separate occasions, 4-7 days apart. Participants delivered 48 balls (8 overs), at five targets on a suspended sheet, situated behind a 'live' batter who stood in a right-handed and left-handed stance for an equal amount of deliveries. Delivery instruction was frequently changed, with all deliveries executed in a pre-planned sequence...
May 22, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28530492/3d-printing-in-liver-surgery-a-systematic-review
#18
Jan Sylwester Witowski, Jasamine Coles-Black, Tomasz Zbigniew Zuzak, Michał Pędziwiatr, Jason Chuen, Piotr Major, Andrzej Budzyński
BACKGROUND: Rapid growth of three-dimensional (3D) printing in recent years has led to new applications of this technology across all medical fields. This review article presents a broad range of examples on how 3D printing is facilitating liver surgery, including models for preoperative planning, education, and simulation. MATERIALS AND METHODS: We have performed an extensive search of the medical databases Ovid/MEDLINE and PubMed/EMBASE and screened articles fitting the scope of review, following previously established exclusion criteria...
May 22, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28530487/effects-of-pre-season-training-on-the-sleep-characteristics-of-professional-rugby-league-players
#19
Heidi R Thornton, Jace A Delaney, Grant M Duthie, Ben J Dascombe
PURPOSE: To investigate the influence of daily and exponentially-weighted moving training loads on subsequent night-time sleep. METHODS: Sleep of fourteen professional rugby league athletes competing in the National Rugby League competition was recorded using wristwatch actigraphy. Physical demands were quantified using GPS technology, including total distance (TD), high-speed distance (HSD), acceleration/deceleration load (SumAccDec; AU), and sRPE (AU). Linear mixed models determined effects of acute (daily) and sub-acute (three- and seven-day) exponentially-weighted moving averages (EWMA) on sleep...
May 22, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28530481/hormone-replacement-therapy-in-pre-menopausal-women-undergoing-bilateral-salpingo-oophorectomy-for-benign-disease-a-review-of-practice
#20
Alison Richardson, Emily West, Mike Cust
Introduction The National Institute for Health and Care Excellence (NICE) guideline on the diagnosis and management of the menopause states that women who are likely to go through the menopause as a result of surgical treatment should be offered information about the menopause and the importance of starting hormonal replacement therapy before they have their treatment. Objectives To determine compliance with NICE guidelines at the Royal Derby Hospital. Study design We undertook a retrospective review of all pre-menopausal women undergoing bilateral salpingo-oophorectomy for benign pathology between 1 January 2016 and 30 June 2016...
January 1, 2017: Post Reproductive Health
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