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https://www.readbyqxmd.com/read/28910916/-primary-tracheal-malignant-glomus-tumor-with-lung-metastasis-diagnosed-by-pathological-analysis-a-case-report-and-literature-review
#1
B Huang, F G Chen, J Zhuang, W C Zheng, W Y Zhu, Q C Zhang, S H Wang, C M Guo, C M Xie
Objective: To study the clinical manifestations, pathological features, diagnosis, differential diagnosis, treatment and prognosis of primary tracheobronchial or pulmonary malignant glomus tumor (MGT). Methods: A case of primary tracheal MGT with lung metastasis diagnosed by pathological analysis admitted to Affiliated Shantou Hospital of Sun Yat-sen University in May. 2015 was analyzed, and the related literatures were reviewed. We searched databases including PubMed, Embase, Ovid, Cochrane, Wanfang and Chinese National Knowledge infrastructure (CNKI), using the keyword "tracheal or bronchial or pulmonary malignant glomus tumor" from Jan...
September 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28904301/a-case-of-gastric-lipoma-resected-by-endoscopic-submucosa-dissection-with-difficulty-in-preoperative-diagnosis
#2
Mizue Ichinose, Takuto Hikichi, Yukiko Kanno, Naohiko Gunji, Masashi Fujita, Masahito Kuroda, Kumiko Terashima, Yoshinori Sato, Satoshi Kawana, Yuko Hashimoto, Hiromasa Ohira, Masayuki Miyata
A 66-year-old man was referred to our hospital with an increasing subepithelial lesion in the gastric antrum. Using esophagogastroduodenoscopy, a tumor with a steep, 20-mm-high rise protruding in the lumen was observed. The mucosal surface of the tumor was reddish, with ulcers forming at the base. Moreover, the tumor was mobile and soft. A biopsy specimen was taken from the ulcer, but tumor tissue was not collected from the submucosa. Endoscopic ultrasonography (EUS) showed a high echoic mass in the submucosa...
September 14, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28902468/fine-needle-aspiration-of-lipoblastoma-cytological-molecular-and-clinical-features
#3
Joana Ferreira, Gonçalo Esteves, Ricardo Fonseca, Carmo Martins, Saudade André, Maria Manuel Lemos
BACKGROUND: Lipoblastomas are rare, benign adipocytic tumors that present mostly during infancy. In about 70% of cases, these tumors carry abnormalities in chromosome 8, mainly leading to rearrangements of the PLAG1 gene. METHODS: We report a series of histologically proven lipoblastomas with previous fine-needle aspiration (FNA) cytology from 9 patients (n = 10 samples) and describe their clinical, cytological, and molecular features. RESULTS: Our cohort included 5 boys and 4 girls (median age, 2...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28898987/typical-and-atypical-granular-cell-tumors-of-soft-tissue-a-clinicopathologic-study-of-50-patients
#4
Matthew Stemm, David Suster, Paul E Wakely, Saul Suster
Objectives: Granular cell tumors are rare neoplasms of neural origin. Despite the mesenchymal nature of these tumors, they rarely occur in the soft tissue, and as a result, this subset is not well characterized. We present the largest case series to date comprising 50 patients with benign and atypical soft tissue granular cell tumors in an effort to better define the pathologic features in this subset of lesions. Methods: All cases of soft tissue granular cell tumors from the Ohio State Medical Center and the Medical College of Wisconsin over a 10-year period were reviewed for histologic and clinical findings...
August 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28894581/positron-emission-tomography-computed-tomography-for-osseous-and-soft-tissue-sarcomas-a-systematic-review-of-the-literature-and-meta-analysis
#5
Aikeremujiang Muheremu, Junyi Ma, Aierken Amudong, Yong Ma, Maimaitiaili Niyazi, Yong Ou, Yuan Ma
In order to elucidate the value of positron emission tomography (PET)/computed tomography (CT) in the clinical diagnosis and treatment of osseous and soft tissue malignancies, two authors independently searched the PubMed, Medline, Elsevier, Embase and Cochrane Library databases for literature published between January 2003 and February 2016, using the key words 'PET/CT', 'positron emission tomography/computed tomography', 'osseous sarcoma', 'bone tumor', 'soft tissue sarcoma' and 'neoadjuvant', to identify prospective and retrospective studies on the applicability of PET/CT on the clinical diagnosis of bone and soft tissue lesions, and evaluation of their response to neoadjuvant therapies...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28893210/distinct-molecular-subtypes-of-uterine-leiomyosarcoma-respond-differently-to-chemotherapy-treatment
#6
Yang An, Shuzhen Wang, Songlin Li, Lulu Zhang, Dayong Wang, Haojie Wang, Shibai Zhu, Wan Zhu, Yongqiang Li, Wenwu Chen, Shaoping Ji, Xiangqian Guo
BACKGROUND: Uterine leiomyosarcoma (ULMS) is an aggressive form of soft tissue tumors. The molecular heterogeneity and pathogenesis of ULMS are not well understood. METHODS: Expression profiling data were used to determine the possibility and optimal number of ULMS molecular subtypes. Next, clinicopathological characters and molecular pathways were analyzed in each subtype to prospect the clinical applications and progression mechanisms of ULMS. RESULTS: Two distinct molecular subtypes of ULMS were defined based on different gene expression signatures...
September 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28891704/mucoepidermoid-carcinoma-in-the-skull-of-an-orange-winged-amazon-parrot-amazona-amazonica
#7
Melissa R Nau, James W Carpenter, Denise Lin, Sanjeev Narayanan, Mackenzie Hallman
A 33-year-old female intact orange-winged Amazon parrot (Amazona amazonica) presented for a slowly growing mass over the right eye. A computed tomography scan performed with and without intravenous contrast revealed a heterogeneous mixed soft tissue and mineral-dense mass with a small area of non-contrast-enhancing fluid density located between the orbits at the caudal aspect of the nasal passages, with associated lysis of the right caudal nasal passage and the right frontal bone. Following euthanasia, the mass was found to consist of soft tissue between the right eye and nostril over the right frontal bone...
September 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28889233/adenoid-cystic-carcinoma-of-the-cavernous-sinus-otolaryngological-sequelae-of-therapy-case-report
#8
Edyta Dzięciołowska-Baran, Aleksandra Gawlikowska-Sroka
A 60-year-old woman, otherwise in a good health condition, was first admitted to the hospital with a year-long tingling sensations of the right half of the face, which gradually turned into severe neuralgia corresponding to maxillary (V2) and mandibular (V3) branches of the right trigeminal nerve. MRI scans of the head revealed an unusual hyperplastic or inflammatory changes along the brain base, cavernous sinus extending toward the pterygopalatine fossa, and lateral pterygoid on the right side. Meningioma was suspected and neuralgia was treated conservatively...
September 10, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28887783/a-novel-integration-of-spectral-domain-optical-coherence-tomography-and-laser-ablation-system-for-precision-treatment
#9
Yingwei Fan, Boyu Zhang, Wei Chang, Xinran Zhang, Hongen Liao
PURPOSE: Complete resection of diseased lesions reduces the recurrence of cancer, making it critical for surgical treatment. However, precisely resecting residual tumors is a challenge during operation. A novel integrated spectral-domain optical-coherence-tomography (SD-OCT) and laser-ablation therapy system for soft-biological-tissue resection is proposed. This is a prototype optical integrated diagnosis and therapeutic system as well as an optical theranostics system. METHODS: We develop an optical theranostics system, which integrates SD-OCT, a laser-ablation unit, and an automatic scanning platform...
September 9, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28882531/primary-cardiac-tumor-presenting-as-left-ventricular-outflow-tract-obstruction-and-complex-arrhythmia
#10
R Fries, S Achen, M T O'Brien, N D Jackson, S Gordon
An adult female mixed breed dog presented for recurrent collapsing episodes over several weeks. Holter evaluation revealed periods of sinus arrest and echocardiography identified a soft tissue mass with subsequent severe dynamic obstruction of the left ventricular outflow tract. The patient was euthanized five days after presentation for severe dyspnea. Necropsy revealed an irregular mass circumferentially lining the left ventricular outflow tract as well as multiple myocardial metastases. The final diagnosis was an undifferentiated pleomorphic endocardial sarcoma...
September 4, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28880600/rare-giant-cell-tumor-of-the-distal-flexor-digitorum-longus-tendon-sheath-and-early-diagnosis-with-use-of-magnetic-resonance-imaging
#11
Michael Levi, Jordan Crafton
Giant-cell tumor of the tendon sheath (GCT-TS) is an uncommon occurrence for a foot and ankle surgeon. However, there is a need to recognize the symptoms of typical and atypical presentations of this pathology. These benign neoplasms are recognized clinically as a soft-tissue mass that is usually painless and palpable. The foot and ankle account for only 3% to 5% of all GCT-TS in the body, with most being located in the hand. Giant cell tumor in the tendon sheath occurring in the foot and ankle is usually encountered on the lateral ankle and dorsum of the foot, occupying the extensor tendons...
July 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28878662/epulis-like-presentation-of-gingival-renal-cancer-metastasis
#12
Gianfilippo Nifosì, Hubert Bressand, Antonio Fabrizio Nifosì, Lorenzo Nifosì, Pierre Damseaux
Mouth metastatic cancers are very rare and they usually represent the evidence of a widespread disease. Common primary tumors are lung carcinoma in men and breast carcinoma in women, followed by kidney cancer. In the oral soft tissues, the gingiva is the most common site, suggesting a possible role of inflammation in the attraction of circulating tumor cells. Oral metastasis has a serious prognosis. In this work, we describe the case of a 58-year-old man affected by renal cancer, who was brought to our attention for the appearance of a gingival swelling...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28877751/inguinal-canal-angioleiomyoma-case-report-of-a-rare-disease-entity-within-inguinal-canal
#13
Jianwen Liu, Rockson Wei, Xuefei Yang, Xinping Shen, Jing Guan, Joe King Man Fan
BACKGROUND: Angioleiomyoma is an uncommon benign soft tissue tumor and originates from the vascular smooth muscle. It often causes pain and is rarely found in inguinal region. We present a rare case of inguinal canal angioleiomyoma of a female patient who suffered from right groin pain for 4 years and mimicking inguinal hernia clinically. PRESENTATION OF CASE: A 53-year-old Chinese female patient presented with 4-year history of right groin pain which was exacerbated by movement...
September 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28877071/uncommon-localization-of-extrarenal-xp11-2-translocation-associated-renal-cell-carcinoma-rcc-case-report
#14
Jaudah Ahmed Al-Maghrabi, Mohamad Nidal Khabaz
The World Health Organization has recognized Xp11.2 translocation-associated renal cell carcinoma (RCC) as a distinct neoplasm that arises within the kidney. Although many reports of extrarenal carcinoma may be found in the literature, to the best of our knowledge, Xp11 translocation-associated RCC with intact kidneys has not been documented. This report describes a multilobulated right retroperitoneal soft tissue mass (7.9×5.3×12.6 cm) of a 37-year-old man complaining of abdominal pain in the right side...
September 4, 2017: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/28877060/clinicopathologic-diversity-of-undifferentiated-sarcoma-with-bcor-ccnb3-fusion-analysis-of-11-cases-with-a-reappraisal-of-the-utility-of-immunohistochemistry-for-bcor-and-ccnb3
#15
Atsuji Matsuyama, Eisuke Shiba, Yoshihisa Umekita, Kanae Nosaka, Takihiro Kamio, Hiroyuki Yanai, Chika Miyasaka, Reiko Watanabe, Ichiro Ito, Tomoko Tamaki, Shinichi Hayashi, Masanori Hisaoka
Undifferentiated sarcoma harboring the BCOR-CCNB3 fusion is characterized by its predilection to affect skeletons of adolescent males, cellular small round/spindle cell morphology, and CCNB3 immunoreactivity. We analyzed 11 cases of BCOR-CCNB3 sarcoma, 10 of which were identified in a reverse transcription-polymerase chain reaction-based screen of 85 patient samples recorded in our database as unclassified small round or spindle cell sarcomas. BCOR rearrangements were confirmed by fluorescence in situ hybridization in 8 tumors...
September 4, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28867117/pet-computed-tomography-and-precision-medicine-musculoskeletal-sarcoma
#16
REVIEW
Asha Kandathil, Rathan M Subramaniam
Skeletal and soft tissue sarcomas need early and accurate diagnosis, staging, and treatment for optimal outcome. (18)F-FDG PET/computed tomography (CT) is indicated in staging of patients with high-grade sarcomas and acts as a surrogate marker of histopathologic grade, guiding biopsy to most aggressive portion of the tumor. Pretherapy and posttherapy (18)F-FDG PET/CT metabolic parameters are reliable indicators of survival in patients with sarcoma with an important role in posttreatment response assessment, enabling the treatment plan to be modified in nonresponders...
October 2017: PET Clinics
https://www.readbyqxmd.com/read/28852946/clinical-pattern-of-primary-systemic-therapy-and-outcomes-of-estrogen-receptor-positive-her2-negative-metastatic-breast-cancer-a-review-of-a-single-institution
#17
Junichiro Watanabe, T Hayashi, Y Tadokoro, S Nishimura, K Takahashi
PURPOSE: In the management of estrogen receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer (ER+HER2-MBC) patients, endocrine therapy (ET) is preferred to chemotherapy (CT) as a primary systemic therapy (PST) when tumor burden is not high. However, there are no definite criteria for choosing a PST, transitioning from ET to CT or using maintenance ET subsequent to CT. METHODS: We reviewed the medical records of 311 ER+HER2-MBC patients who underwent CT from September 2002 to December 2016 and assessed their outcomes...
August 29, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28851899/the-diagnostic-and-prognostic-value-of-interleukin-6-in-patients-with-soft-tissue-sarcomas
#18
Tomohito Hagi, Tomoki Nakamura, Takahiro Iino, Takao Matsubara, Kunihiro Asanuma, Akihiko Matsumine, Akihiro Sudo
The presence of systemic inflammation has been reported to be associated with poor prognosis in patients with soft tissue sarcoma (STS). The cytokine interleukin-6 (IL-6) has pleiotropic effects on various cell types in the tumor microenvironment. The aim of the present study was to determine whether serum IL-6 levels could be useful to assume the differentiation of benign soft tissue tumors from STS and to investigate the possible value of IL-6 for survival and oncological events in patients with STS. The medical records of 99 patients who underwent surgical resection were retrospectively reviewed...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28844590/surgical-approaches-anaesthetic-management-and-outcome-in-pediatric-superior-mediastinal-tumors
#19
Gehad Ahmed, Mohammed M Hegazy, Tarek Raafat, Hanafy Hafez, Sayed Fadel, Maged Elshafiey
BACKGROUND: Pediatric superior mediastinal tumors are a heterogeneous group of tumors with marked variation in pathology and extension. We reviewed our experience with different surgical approaches to tumors originating from or extending to superior mediastinum in pediatrics. PATIENTS AND METHODS: The medical records of all patients who had undergone resection for superior mediastinal tumors in Children's Cancer Hospital - Egypt, between January 2008 to December 2015, were reviewed for demographic data, clinico-pathological features, radiologic findings, operative techniques and outcome...
August 22, 2017: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/28840026/ectopic-right-parietal-pleural-thymic-carcinoma-a-rare-case-and-review-of-the-literature
#20
Haoshuai Zhu, Yiyan Lei, Jianyong Zou, Chunhua Su, Bo Zeng, Yan Li, Honghe Luo
Ectopic thymic carcinoma is extremely rare. We present a case of a 73-year-old male patient with ectopic right parietal pleural thymic carcinoma and performed a literature review. Computed tomography (CT) of the chest demonstrated a sharp-edged soft tissue mass with intense enhancement measuring 47 mm × 29 mm with a broader base adjacent to the right axillary chest wall at the level of the 5th rib. There was no hilar or mediastinal lymphadenopathy or evidence of a mediastinal tumor or pleural nodules. A totally extra-pleural tumor resection and partial right lung resection was performed...
July 2017: Journal of Thoracic Disease
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