keyword
https://read.qxmd.com/read/38464583/hair-removal-laser-induced-fox-fordyce-disease-emerging-on-the-axillary-and-pubic-areas-report-of-a-case-and-review-of-literature
#21
Mozhdeh Sepaskhah, Rahil Hamedpour, Fatemeh Sari Aslani
KEY CLINICAL MESSAGE: Fox-Fordyce disease is a recognized adverse effect of depilating lasers. It should be considered among the differential diagnoses of the pruritic perifollicular papules that occur at the hair removal laser treatment site, including Alex/Diode laser. ABSTRACT: Fox-Fordyce disease (FFD) is an uncommon skin disorder affecting the apocrine sweat glands and presents as pruritic skin-colored papules, mainly on the axillary and pubic areas. Some predisposing factors are proposed, including hormonal changes...
March 2024: Clinical Case Reports
https://read.qxmd.com/read/38463136/successful-treatment-of-erosive-lichen-planus-with-tofacitinib-a-case-series-and-review-of-the-literature
#22
REVIEW
Parvin Mansouri, Mohammad Amin Jafari, Reza Chalangari, Masoumeh Roohaninasab, Azadeh Goodarzi
Lichen planus (LP) is an inflammatory disease that affects the skin, hair, nails and mucous membranes. Erosive LP is a chronic and difficult-to-treat subtype of lichen planus, characterized by lesions on mucosal surfaces, particularly in the oral and genital areas. The prevalence of erosive LP has not been determined. To date, treatment has consisted of surgical intervention, photodynamic therapy, laser therapy, and systemic or topical drugs, including steroids and immunomodulatory agents. LP usually need longer periods of treatment and are known as precancerous lesions with a 0...
2024: Clinical Medicine Insights. Case Reports
https://read.qxmd.com/read/38462706/combined-microfocused-ultrasound-and-delicate-pulsed-light-for-facial-rejuvenation-a-prospective-randomized-and-split-face-study
#23
JOURNAL ARTICLE
Yawen Wang, Jingchen Liang, Ying Chen, Jun Xia, Yanting Liu, Jing Liu, Youbao Li, Mengyao Yang, Zhao Wang, Weihui Zeng
OBJECTIVES: Public's interest in noninvasive skin rejuvenation treatments continues to grow. The advantage of combination therapy lies in that it can target different aspects of skin rejuvenation. This study aimed to assess the efficacy and safety of microfocused ultrasound (MFU) combined with delicate pulsed light (DPL) for facial rejuvenation. METHODS: Twenty-one patients with facial relaxation were enrolled. All patients received whole-face MFU treatment, and one side of the face was randomly assigned to receive DPL...
March 10, 2024: Lasers in Surgery and Medicine
https://read.qxmd.com/read/38462597/ce6-modified-fe-ions-doped-carbon-dots-as-multifunctional-nanoplatform-for-ferroptosis-and-photodynamic-synergistic-therapy-of-melanoma
#24
JOURNAL ARTICLE
Haiqiu Li, Yichen Dou, Hang Yang, Hanlin Xing, Cheng Zhu, Tao Wang, Zhaopeng Xuan, Mingxi Yang
BACKGROUND: Despite the higher sensitivity of melanoma towards ferroptosis and photodynamic therapy (PDT), the lack of efficient ferroptosis inducers and the poor solubility of photosensitizers restrict their synergistic strategies. With unique advantages, carbon dots (CDs) are expected to serve as innovative building blocks for combination therapy of cancers. RESULTS: Herein, an ferroptosis/PDT integrated nanoplatform for melanoma therapy is constructed based on chlorin e6-modified Fe ions-doped carbon dots (Fe-CDs@Ce6)...
March 10, 2024: Journal of Nanobiotechnology
https://read.qxmd.com/read/38460899/prolidase-activity-assays-a-survey-of-the-reported-literature-methodologies
#25
REVIEW
Serena Fiorito, Salvatore Genovese, Francesco Epifano, Chiara Collevecchio
Prolidase (EC.3.4.13.9) is a dipeptidase known nowadays to play a pivotal role in several physiological and pathological processes. More in particular, this enzyme is involved in the cleavage of proline- and hydroxyproline-containing dipeptides (imidodipeptides), thus finely regulating the homeostasis of free proline and hydroxyproline. Abnormally high or low levels of prolidase have been found in numerous acute and chronic syndromes affecting humans (chronic liver fibrosis, viral and acute hepatitis, cancer, neurological disorders, inflammation, skin diseases, intellectual disability, respiratory infection, and others) for which the content of proline is well recognized as a clinical marker...
March 7, 2024: Analytical Biochemistry
https://read.qxmd.com/read/38460441/skin-perfusion-and-oxygen-saturation-after-mastectomy-and-radiation-therapy-in-breast-cancer-patients
#26
JOURNAL ARTICLE
Sherif Elawa, Ingemar Fredriksson, Ingrid Steinvall, Johan Zötterman, Simon Farnebo, Erik Tesselaar
The pathophysiological mechanism behind complications associated with postmastectomy radiotherapy (PMRT) and subsequent implant-based breast reconstruction are not completely understood. The aim of this study was to examine if there is a relationship between PMRT and microvascular perfusion and saturation in the skin after mastectomy and assess if there is impaired responsiveness to a topically applied vasodilator (Methyl nicotinate - MN). Skin microvascular perfusion and oxygenation >2 years after PMRT were measured using white light diffuse reflectance spectroscopy (DRS) and laser Doppler flowmetry (LDF) in the irradiated chest wall of 31 women with the contralateral breast as a control...
March 6, 2024: Breast: Official Journal of the European Society of Mastology
https://read.qxmd.com/read/38459660/dihydrocapsaicin-suppresses-the-sting-mediated-accumulation-of-ros-and-nlrp3-inflammasome-and-alleviates-apoptosis-after-ischemia-reperfusion-injury-of-perforator-skin-flap
#27
JOURNAL ARTICLE
Yingying Lai, Ningning Yang, Xuankuai Chen, Xianhui Ma, Zhuliu Chen, Chengji Dong, Gaoxiang Yu, Yingying Huang, Donghao Shi, Pin Fang, Kejian Fu, Renhao Jiang, Cong Mao, Jian Ding, Weiyang Gao
Avascular necrosis frequently occurs as a complication following surgery involving the distal perforator flap. Dihydrocapsaicin (DHC) can protect tissue from ischemia-reperfusion (I/R) injury, but its specific role in multizone perforator flaps remains unclear. In this study, the prospective target of DHC in the context of I/R injury was predicted using network pharmacology analysis. Flap viability was determined through survival area analysis, laser Doppler blood flow, angiograms, and histological examination...
March 8, 2024: Phytotherapy Research: PTR
https://read.qxmd.com/read/38459617/angiolymphoid-hyperplasia-with-eosinophilia-and-kimura-disease-a-case-report-and-literature-review
#28
Elizabeth Botto, Paul Rodriguez-Waitkus, Sharon E Albers
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign vascular proliferative condition, typically presenting as subcutaneous nodules in the head and neck region of middle-aged women. Kimura disease (KD) is a benign condition that presents with subcutaneous nodules in a similar distribution with lymphadenopathy and eosinophilia, typically in Asian adult males. These diseases are often discussed together, including whether they exist on a spectrum or if they represent separate disease entities. Both are very rare in the pediatric population; in this report we highlight the case of a 10-year-old Caucasian male presenting with ALHE and KD...
March 8, 2024: Pediatric Dermatology
https://read.qxmd.com/read/38456556/efficacy-and-safety-of-the-combination-of-oral-tranexamic-acid-and-intense-pulsed-light-versus-oral-tranexamic-acid-alone-in-the-treatment-of-refractory-riehl-s-melanosis-a-prospective-comparative-study
#29
JOURNAL ARTICLE
Zhongyi Xu, Chen Wang, Xiaoxue Xing, Chengfeng Zhang, Leihong Flora Xiang
BACKGROUND: There is no standardized and effective treatment modality for Riehl's melanosis. AIMS: To compare the efficacy and safety of oral tranexamic acid (TXA) combined with intense pulsed light (IPL) versus TXA alone in the treatment of refractory Riehl's melanosis. METHODS: A prospective study of 28 subjects with refractory Riehl's melanosis and Fitzpatrick Skin Types III or IV was conducted. All subjects received oral TXA 500 mg daily and 11 of them were treated in combination with monthly IPL therapy for 6 months...
March 8, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38456485/extreme-makeover-filler-edition-non-surgical-correction-for-facial-deformities-post-trauma
#30
Ilaria Proietti, Francesca Svara, Chiara Battilotti, Ersilia Tolino, Nicoletta Bernardini, Nevena Skroza, Concetta Potenza
No abstract text is available yet for this article.
March 8, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38456369/diagnosis-and-therapy-of-actinic-keratosis
#31
JOURNAL ARTICLE
Janis Raphael Thamm, Julia Welzel, Sandra Schuh
Actinic keratosis (AK) is considered a chronic and recurring in situ skin neoplasia, with a possible transformation into invasive squamous cell carcinoma (SCC). Among others, predominant risk factors for development of AK are UV-light exposure and immunosuppression. Basal epidermal keratinocyte atypia (AK I) and proliferation (PRO score) seem to drive malignant transformation, rather than clinical appearance of AK (Olsen I-III). Due to the invasiveness of punch biopsy, those histological criteria are not regularly assessed...
March 8, 2024: Journal der Deutschen Dermatologischen Gesellschaft: JDDG
https://read.qxmd.com/read/38455658/infertility-in-fabry-s-disease-role-of-hypoxia-and-inflammation-in-determining-testicular-damage
#32
JOURNAL ARTICLE
Luigi Sansone, Federica Barreca, Manuel Belli, Michele Aventaggiato, Andrea Russo, Giulietta A Perrone, Matteo A Russo, Marco Tafani, Andrea Frustaci
INTRODUCTION: Fabry's disease (FD) is a genetic X-linked systemic and progressive rare disease characterized by the accumulation of globotriaosylceramide (GB3) into the lysosomes of many tissues. FD is due to loss-of-function mutations of α-galactosidase, a key-enzyme for lysosomal catabolism of glycosphingolipids, which accumulate as glycolipid bodies (GB). In homozygous males the progressive deposition of GB3 into the cells leads to clinical symptoms in CNS, skin, kidney, etc...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38452322/a-systematic-review-on-treatment-outcomes-of-striae
#33
JOURNAL ARTICLE
Catherine Keying Zhu, Lorena Alexandra Mija, Kaouthar Koulmi, Benjamin Barankin, Ilya Mukovozov
BACKGROUND: Striae are fine lines on the body that occur following rapid skin stretching (i.e., following pregnancy, puberty, weight change). The aim of this systematic review was to assess the current literature on treatment outcomes associated with striae. OBJECTIVE: (1) To assess the efficacy and safety of different treatment options reported for striae and (2) to determine the most efficient treatment options for each subtype of striae. METHODS: A systematic search was performed on MEDLINE, Embase, and PubMed with no publication date or language restrictions...
March 7, 2024: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://read.qxmd.com/read/38450959/a-pilot-study-on-the-efficacy-of-a-seaweed-mud-application-in-the-treatment-of-cellulite
#34
JOURNAL ARTICLE
Domenico Amuso, Alessandro Medoro, Giovanni Scapagnini, Angela Gambacorta, Sergio Davinelli, Eugenio Luigi Iorio, Luca Reggiani Bonetti, Andrea Sbarbati
BACKGROUND: Cellulite represents a common multi-factorial condition that affects nearly all women and is now recognized as a clinical condition associated with systemic factors and negative psychological effects. Several noninvasive and minimally invasive treatments were developed during the last few years, but limited evidence supports many of them due to lack of evidence, insufficient participants, and potential adverse effects. METHODS: This study aimed to evaluate the efficacy of a seaweed mud application in improving both the structure and function of tissues affected by cellulite...
March 7, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38450923/the-potential-of-paeonia-lactiflora-pall-seeds-oil-as-a-pure-natural-cosmetics-raw-material-in%C3%A2-vitro-findings
#35
JOURNAL ARTICLE
Zhixiong Chen, Ni Hong, Cui Yan, Zhongbo Zheng, Jie Xi, Ping Cao
BACKGROUND: As a traditional Chinese herbal medicine, Paeonia lactiflora Pall is rich in various active ingredients such as polysaccharides and total flavonoids while having ornamental value. It has potential application value in the development of food and cosmetics. OBJECTIVE: To study the in vitro efficacy of Paeonia lactiflora Pall seeds oil. METHODS: Firstly, the levels of linolenic acid and linoleic acid in Paeonia lactiflora Pall seeds oil were quantified using gas chromatography...
March 7, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38450900/revitalizing-the-lower-face-therapeutic-insights-and-an-innovative-treatment-guideline-for-jowl-rejuvenation
#36
JOURNAL ARTICLE
Fabiano Nadson Magacho-Vieira, Luíza Jorgiana Riotinto Bezerra, Daniel Boro, Fernanda Araújo Santos
BACKGROUND: The intricate mechanisms of jowl formation, which ultimately lead to loss of lower jaw definition, skin laxity, and localized fat accumulation, involve interrelated factors such as skin aging, fat redistribution, muscle dynamics, and loss of support. AIMS: To propose a structured approach to the treatment of the jowl area that is comprehensive and tailored to the needs of each individual patient. MATERIALS AND METHODS: This integrative review combines a meticulous analysis of the literature with practical insights from real-world clinical settings...
March 7, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38450826/the-effects-of-a-real-time-temperature-monitoring-non-ablative-monopolar-radiofrequency-technology-on-vulvovaginal-atrophy-symptoms-in-postmenopausal-chinese-women
#37
JOURNAL ARTICLE
Vivian Cheng, William Tai Chi-Shing, Athena Lee, Rita Lee
BACKGROUND: Vulvovaginal atrophy (VVA) includes a wide range of conditions affecting the reproductive and urinary systems, often requiring careful evaluation and management for optimal health. AIMS: This study aims to evaluate the symptom management effects of a real time temperature-monitored non-ablative RF device for the treatment of postmenopausal Chinese women with VVA symptoms. METHODS: This pilot study involved 24 postmenopausal Chinese women with one or more VVA symptoms, who wished to remain sexually active...
March 7, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38448367/melasma-and-reflectance-confocal-microscopy-from-baseline-to-treatment-monitoring
#38
REVIEW
Stefania Guida, Caterina Longo, Riccardo Ronga, Giorgio Stabile, Antonio Podo Brunetti, Gianmarco D Bigotto, Claudio Conforti, Silvana Ciardo, Carmen Cantisani, Giovanni Paolino, Santo R Mercuri, Steven P Nisticò, Nicola Zerbinati, Franco Rongioletti, Giovanni Pellacani
Melasma is a frequent condition worldwide, and it represents one of the most challenging disorders to treat in cosmetic dermatology. One of the critical factors for treatment prognosis is the assessment of the depth and distribution of pigment within the hyperpigmented area. Nowadays, non-invasive skin imaging techniques, such as reflectance confocal microscopy (RCM), have been used to estimate pigment distribution and depth within different skin layers. This article aims to provide a systematic review of RCM applications in melasma, providing terminology and investigating characteristics of melasma at baseline and after medical and laser treatment...
March 6, 2024: International Journal of Dermatology
https://read.qxmd.com/read/38447098/keratosis-pilaris-treatment-paradigms-assessing-effectiveness-across-modalities
#39
JOURNAL ARTICLE
Pooi C Wong, Madeline A Wang, Tangqi J Ng, Hossein Akbarialiabad, Dédée F Murrell
This review aims to present a comprehensive synthesis of the existing treatment modalities for keratosis pilaris (KP) and evaluate their therapeutic efficacy. Keratosis pilaris (KP) is a prevalent chronic dermatological condition typified by its unique 'chicken skin appearance', with the cheeks being the most commonly involved sites. Numerous therapeutic interventions have emerged, given its substantial prevalence and impact on skin aesthetics and psychological well-being. Nonetheless, a consistent therapeutic response has been challenging to achieve...
March 6, 2024: Clinical and Experimental Dermatology
https://read.qxmd.com/read/38444628/carbon-dioxide-laser-for-precise-and-bloodless-contouring-of-soft-tissue-ahead-of-skin-grafting-a-case-example-of-technique-and-benefits
#40
Parisa Moori, Laura Cappuyns, Kayvan Shokrollahi
Scarring is a dynamic development as a result of the wound healing process. Post-burn scars are often hypertrophic in nature and thus exhibit a much thicker and firmer scar, often leading to contractures. Various strategies have been implemented by burns surgeons to endeavour to mitigate and improve such symptoms and appearances . Laser therapy in the control of hypertrophic scarring is of continual developing interest within this field. We demonstrate the advantageous, intra-operative use of a carbon dioxide laser for precise contouring of a burn scar prior to skin grafting in a 36 year-old female with hypertrophic scarring following a 65% total body surface area flash flame burn...
June 2024: JPRAS Open
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