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https://www.readbyqxmd.com/read/27911144/comparison-of-pulsed-dye-laser-versus-combined-pulsed-dye-laser-and-nd-yag-laser-in-the-treatment-of-inflammatory-acne-vulgaris
#1
Manal Mohamed Salah El Din, Nevien Ahmed Samy, Amira Eid Salem
BACKGROUND: Both pulsed dye laser and combined 585/1,064-nm (sequential dual-wave-length PDL and Nd:YAG) laser improves inflammatory skin disorders including acne vulgaris. OBJECTIVE: To compare the efficacy of 585 nm pulsed dye laser versus sequential dual-wave-length PDL and Nd:YAG in treatment of acne vulgaris. PATIENTS AND METHOD: Thirty patients complaining of acne vulgaris were treated with a single pass of PDL alone on half of the face and a single pass of combined 585/1064-nm laser on the other half for four treatment sessions at 2 weeks interval, then assessed by the count and severity of the acne lesions & digital camera photographs Results: The study showed that inflammatory acne lesions count was significantly reduced by 82...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27911117/are-lasers-superior-to-lights-in-the-photoepilation-of-fitzpatrick-v-and-vi-skin-types-a-comparison-between-nd-yag-laser-and-intense-pulsed-light
#2
Bibilash Bs, Ravi Kumar Chittoria, Devinder Mohan Thappa, Devi Prasad Mohapatra, Friji M T, Dineshkumar S, Sandhya Pandey
BACKGROUND AND OBJECTIVES: There are no large volume comparative studies available to compare the efficacy of lasers over lights for hair removal in Fitzpatrick V and VI skin types. This study is designed to compare the efficacy of Nd:YAG Laser versus IPL in the darker skin types. STUDY DESIGN/MATERIALS AND METHODS: Thirty nine patients included in Group-1 were treated with Nd:YAG and 31 in group-2 with IPL. Both groups received 5 sessions of treatment. The hair counts were assessed using digital photography and manual counting method before and after treatment and results were analysed...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27906359/monitoring-blood-vital-bio-signs-using-secondary-speckle-patterns
#3
Talia Sirkis, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman, Zeev Zalevsky
Continuous noninvasive measurement of vital bio-signs, such as cardiopulmonary parameters, is an important tool in the evaluation process of the patient's physiological condition and in the health monitoring of the patient. On the demand of new enabling technologies, some works have been done in continuous monitoring of blood pressure and pulse wave velocity. In this paper, we introduce further application of a novel technique for remote noncontact blood pulse wave velocity and pressure measurement based on tracking the temporal changes of reflected secondary speckle patterns produced in human skin when illuminated by a laser beam...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906358/monitoring-blood-vital-bio-signs-using-secondary-speckle-patterns
#4
Talia Sirkis, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman, Zeev Zalevsky
Continuous noninvasive measurement of vital bio-signs, such as cardiopulmonary parameters, is an important tool in the evaluation process of the patient's physiological condition and in the health monitoring of the patient. On the demand of new enabling technologies, some works have been done in continuous monitoring of blood pressure and pulse wave velocity. In this paper, we introduce further application of a novel technique for remote noncontact blood pulse wave velocity and pressure measurement based on tracking the temporal changes of reflected secondary speckle patterns produced in human skin when illuminated by a laser beam...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27905610/dendritic-polyglycerol-and-n-isopropylacrylamide-based-thermoresponsive-nanogels-as-smart-carriers-for-controlled-delivery-of-drugs-through-the-hair-follicle
#5
Fitsum Feleke Sahle, Michael Giulbudagian, Julian Bergueiro, Jürgen Lademann, Marcelo Calderón
Nanoparticles with a size of several hundred nanometers can effectively penetrate into the hair follicles and may serve as depots for controlled drug delivery. However, they can neither overcome the hair follicle barrier to reach the viable cells nor release the loaded drug adequately. On the other hand, small drug molecules cannot penetrate deep into the hair follicles. Thus, the most efficient way for drug delivery through the follicular route is to employ nanoparticles that can release the drug close to the target structure upon exposure to some external or internal stimuli...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27900332/lasers-and-energy-devices-for-the-skin-conventional-and-unconventional-use
#6
EDITORIAL
Steven Paul Nistico, Andrea Chiricozzi, Federica Tamburi, Giovanni Cannarozzo
No abstract text is available yet for this article.
2016: BioMed Research International
https://www.readbyqxmd.com/read/27899298/mechanisms-and-time-course-of-menthol-induced-cutaneous-vasodilation
#7
Daniel H Craighead, Nathaniel B McCartney, James H Tumlinson, Lacy M Alexander
Menthol is a vasoactive compound that is widely used in topical analgesic agents. Menthol induces cutaneous vasodilation, however the underlying mechanisms are unknown. Determining the rates of appearance and clearance of menthol in the skin is important for optimizing topical treatment formulation and dosing. The purpose of this study was to determine the mechanisms contributing to menthol-mediated cutaneous vasodilation and to establish a time course for menthol appearance/clearance in the skin. Ten young (23±1years, 5 males 5 females) subjects participated in two protocols...
November 26, 2016: Microvascular Research
https://www.readbyqxmd.com/read/27896345/high-performance-flexible-strain-sensor-based-on-self-locked-overlapping-graphene-sheets
#8
Dan-Yang Wang, Lu-Qi Tao, Ying Liu, Tian-Yu Zhang, Yu Pang, Qian Wang, Song Jiang, Yi Yang, Tian-Ling Ren
Strain sensors have been widely used in the fields of wearable devices, robot arms, medical sensing, bio-sensing, artificial skin and so on, but the existing strain sensors have some shortcomings such as a limited gauge factor (GF) or strain range. We fabricate a novel and flexible strain sensor with high performance based on self-locked overlapping graphene sheets (SOGS) which can be used for wearable devices. Polydimethylsiloxane (PDMS) is used to lock the overlapping graphene sheets, and then the graphene can be stretched and achieve an ultrahigh GF...
November 29, 2016: Nanoscale
https://www.readbyqxmd.com/read/27896221/microvascular-blood-flow-improvement-in-hyperglycemic-obese-adult-patients-by-hypocaloric-diet
#9
T Mastantuono, M Di Maro, M Chiurazzi, L Battiloro, N Starita, G Nasti, D Lapi, L Iuppariello, M Cesarelli, G D'Addio, A Colantuoni
The present study was aimed to assess the changes in skin microvascular blood flow (SBF) in newly diagnosed hyperglycemic obese subjects, administered with hypocaloric diet. Adult patients were recruited and divided in three groups: NW group (n=54), NG (n=54) and HG (n=54) groups were constituted by normal weight, normoglycemic and hyperglycemic obese subjects, respectively. SBF was measured by laser Doppler perfusion monitoring technique and oscillations in blood flow were analyzed by spectral methods under baseline conditions, at 3 and 6 months of dietary treatment...
November 2016: Translational Medicine @ UniSa
https://www.readbyqxmd.com/read/27891612/neurovascular-mechanisms-underlying-augmented-cold-induced-reflex-cutaneous-vasoconstriction-in-human-hypertension
#10
Jody L Greaney, W Larry Kenney, Lacy M Alexander
Despite ample evidence of dysregulated sympathetic control of the peripheral vasculature in hypertension, no studies have examined integrated neurovascular function during cold stress in hypertensive adults (HTN). We hypothesized that (1) whole-body cooling would elicit greater cutaneous vasoconstriction and greater increases in skin sympathetic nervous system activity (SSNA) in HTN (n = 14; 56 ± 2 yrs) compared to age-matched normotensive adults (NTN; n = 14; 55 ± 2 yrs) and (2) augmented reflex vasoconstriction in HTN would be mediated by an increase in cutaneous vascular adrenergic sensitivity and a greater contribution of non-adrenergic sympathetic co-transmitters...
November 28, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27888888/laser-assisted-delivery-to-treat-facial-scars
#11
REVIEW
Jill S Waibel, Ashley Rudnick
Treatment of facial scars is a multispecialty endeavor for optimal patient recovery. One new innovation helping in facial scar treatments are lasers. Fractional laser predictably (tunable) disrupts the barrier of the skin creating deep channels that allow the delivery of drug and cellular materials; this is called laser-assisted drug delivery (LAD). Without exception thus far, LAD has been found to enhance the local uptake of any drug or substance applied to the skin. These zones may be used postoperatively to deliver drugs and other substances to create an enhanced scar therapeutic response to drug or substance applied to the skin...
February 2017: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/27885682/fractional-laser-assisted-drug-uptake-impact-of-time-related-topical-application-to-achieve-enhanced-delivery
#12
Christina A Banzhaf, Daniel Thaysen-Petersen, Christiane Bay, Peter A Philipsen, Mette Mogensen, Tarl Prow, Merete Haedersdal
BACKGROUND AND OBJECTIVE: Ablative fractional laser (AFXL) is acknowledged to increase uptake of topically applied agents in skin. AFXL channels gradually close over time, which may impair this capability. The time frame for applying a drug after AFXL exposure remains to be established. The aim of this study, was to investigate the importance of time-related topical application after AFXL exposure and to relate resultant uptake in skin with AFXL channel morphology and skin integrity. STUDY DESIGN/MATERIALS AND METHODS: Buttock skin of healthy volunteers (n = 11) was exposed to 10,600 nm fractional CO2 laser using 5% density, 120 μm beam diameter, 15 mJ pulse energy...
November 25, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27885522/efficacy-and-safety-of-fractional-co2-laser-versus-fractional-er-yag-laser-in-the-treatment-of-facial-skin-wrinkles
#13
Reza M Robati, Elmira Asadi
Ablative fractional lasers were introduced for treating facial rhytides. Few studies have compared fractional CO2 and Er:YAG lasers on cutaneous photodamages by a split trial. The aim of the present study was to compare these modalities in a randomized controlled double-blind split-face design with multiple sessions and larger sample size compared to previous studies done before. Forty patients with facial wrinkles were enrolled. Patients were randomly assigned to receive three monthly treatments on each side of the face, one with a fractional CO2 and one with a fractional Er:YAG laser...
November 24, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27885520/the-effect-of-pre-operative-topical-anaesthetic-cream-on-the-ablative-width-and-coagulative-depth-of-ablative-fractional-resurfacing-laser
#14
Preawphan Punyaratabandhu, Rungsima Wanitphakdeedecha, Penvadee Pattanaprichakul, Panitta Sitthinamsuwan, Weeranut Phothong, Sasima Eimpunth, Visnu Lohsiriwat, Woraphong Manuskiatti
Topical anaesthetic cream (TAC) is commonly used as a pre-treatment of ablative fractional resurfacing (AFR) laser. Most of anaesthetic cream contains distilled water as major component. Therefore, pre-operative TAC may interfere the photothermal reaction in the skin treated with fractional carbon-dioxide (FCO2) laser and fractional erbium-doped yttrium aluminium garnet (FEr:YAG) laser. The objective of the study was to compare the ablative width (AW) and coagulative depth (CD) of AFR laser with and without pre-treatment with TAC...
November 24, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27885499/the-effects-of-alpha-1-adrenoceptor-blockade-and-angiotensin-converting-enzyme-inhibition-on-central-and-brachial-blood-pressure-and-vascular-reactivity-the-doxazosin-ramipril-study
#15
Andreas Jekell, Majid Kalani, Thomas Kahan
We aimed to study whether inhibition of the renin-angiotensin-aldosterone system has effects on vascular structure and function beyond the effects on blood pressure reduction alone. Patients with mild-to-moderate hypertension (n = 61, age 54 ± 12 years, 34% women) received the angiotensin converting enzyme inhibitor ramipril 10 mg or the alpha 1-adrenoceptor blocker doxazosin 8 mg double-blind for 12 weeks. Aortic blood pressure, pulse wave velocity, and augmentation index were assessed by applanation tonometry...
November 24, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27884347/fabrication-of-three-dimensional-scan-to-print-ear-model-for-microtia-reconstruction
#16
Byoungjun Jeon, Chiwon Lee, Myungjoon Kim, Tae Hyun Choi, Sungwan Kim, Sukwha Kim
BACKGROUND: Microtia is a congenital deformity of the external ear that occurs in 1 of every 5000 births. Microtia reconstruction using traditional two-dimensional templates does not provide highly detailed ear shapes. Here, we describe the feasibility of using a three-dimensional (3D) ear model as a reference. MATERIALS AND METHODS: Seven children aged from 11 to 16 (6 grade III and 1 grade II microtia) were recruited from Seoul National University Children's Hospital, Korea...
December 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27884327/inhibition-of-c-jun-n-terminal-kinase-signaling-suppresses-skin-flap-apoptosis-in-a-rat-ischemia-and-or-reperfusion-model
#17
Ming Bai, Yifang Liu, Dechang Yin, Mingzi Zhang, Youbin Wang, Xuemei Ma, Yunqi Liu, Pengxiang Zhao
BACKGROUND: The goals of this study were to validate the role of c-Jun N-terminal kinase (JNK) activation in skin flap apoptosis in a rat model of abdomen skin ischemia and/or reperfusion (IR) and to compare the protective effect of SP600125 and hydrogen-rich saline in skin IR injury. METHODS: Male Sprague-Dawley rats were divided into five groups: one sham surgery group and four surgery groups. Before undergoing 3 h of IR management, the surgery groups were treated with normal saline (IR), dimethyl sulfoxide, SP600125 (SP), and hydrogen-rich saline (H)...
December 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27882385/a-role-for-neuregulin-1-in-promoting-keloid-fibroblast-migration-via-erbb2-mediated-signaling
#18
Natalie Jumper, Tom Hodgkinson, Ralf Paus, Ardeshir Bayat
Keloid disease is a fibroproliferative tumour characterised by aggressive local invasion, evident from a clinically and histologically active migrating margin. During combined laser capture microdissection and microarray analysis-based in situ gene expression profiling, we identified upregulation of the polypeptide growth factor neuregulin-1 (NRG1) and ErbB2 oncogene in keloid margin dermis, leading to the hypothesis that NRG1 contributed to keloid margin migration through ErbB2-mediated signalling. The aim of this study was to probe this hypothesis through functional in vitro studies...
November 24, 2016: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/27878858/non-invasive-tools-for-the-diagnosis-of-cutaneous-melanoma
#19
REVIEW
C Fink, H A Haenssle
BACKGROUND: While the excisional biopsy and histological examination of suspicious lesions remains the current gold standard for diagnosing cutaneous melanoma (CM), there is a demand for more objective and non-invasive examination methods that may support clinicians in their decision when to biopsy or not. METHODS: This review is based on publications and guidelines retrieved by a selective search in PubMed and MEDLINE and focused on non-invasive diagnostic strategies for detecting melanoma...
November 22, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27878794/varicosities-of-the-lower-extremity-new-approaches-cosmetic-or-therapeutic-needs
#20
Luca Spinedi, Heiko Uthoff, Sasan Partovi, Daniel Staub
Varicose veins of the lower extremity (VVLE) are a frequently encountered vascular disorder in the general population. The general view that VVLE are a non-serious disease with primarily aesthetic impact is a common misconception, as the disease can have a significant negative impact on generic and disease-specific quality of life. Further, VVLE may be associated with potentially threatening clinical conditions, such as chronic venous ulceration, venous thromboembolism and haemorrhage from ruptured varicose veins...
2016: Swiss Medical Weekly
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