Melika Motamedi, Maggie Zx Xiao, Jean Deschenes, Jori Hardin, Russell Sterrett, Lesley Street, Minakshi Taparia, Etienne Mahe, Giovanni Ferrara, James R Barrie, Robert Gniadecki
BACKGROUND: Granulomatous mycosis fungoides (GMF) is a rare form of cutaneous T-cell lymphoma characterized by a granulomatous inflammatory infiltrate. OBJECTIVE: The impact of granulomatous inflammation on the prognosis of the disease remains controversial as there are both favorable and unfavorable outcomes documented. METHODS: We performed a systematic review of 116 GMF cases previously described in the literature. RESULTS: In contrast to the classic Alibert-Bazin type of mycosis fungoides (MF), cutaneous lesions in GMF tend to involve distal extremities (lower legs, feet, hands) early in the disease course...
February 29, 2024: Dermatology: International Journal for Clinical and Investigative Dermatology