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https://www.readbyqxmd.com/read/28802393/paediatric-injection-medialisation-laryngoplasty-recent-great-ormond-street-hospital-experience
#1
K A Stephenson, L Cavalli, A Lambert, J Fleming, E Lawes, S Gupta, C G Jephson, L A Cochrane
INTRODUCTION: Unilateral vocal fold paresis may significantly impair the vocal quality and laryngeal competence of a child. Relatively little literature relates to injection medialisation laryngoplasty (IML) in children and previous reports have involved small numbers of heterogenous cases. METHODS: A retrospective review was conducted of paediatric patients managed by our multidisciplinary specialist voice clinic undergoing IML for unilateral vocal fold paresis...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28799928/greywater-characterization-and-handling-practices-among-urban-households-in-ghana-the-case-of-three-communities-in-kumasi-metropolis
#2
Bismark Dwumfour-Asare, Philomina Adantey, Kwabena Biritwum Nyarko, Eugene Appiah-Effah
Greywater management in Ghana receives little or no attention although untreated greywater is associated with environmental and public health risks. This paper assesses greywater characteristics and handling practices among urban households in three selected communities in Kumasi, the second largest city of Ghana. The study involved in-depth surveys (interviews and observations) with 90 households, and collection of 18 greywater samples from nine greywater sources for laboratory analysis. Average greywater generation is 43...
August 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28757907/mind-your-crossings-mining-gis-imagery-for-crosswalk-localization
#3
Dragan Ahmetovic, Roberto Manduchi, James M Coughlan, Sergio Mascetti
For blind travelers, finding crosswalks and remaining within their borders while traversing them is a crucial part of any trip involving street crossings. While standard Orientation & Mobility (O&M) techniques allow blind travelers to safely negotiate street crossings, additional information about crosswalks and other important features at intersections would be helpful in many situations, resulting in greater safety and/or comfort during independent travel. For instance, in planning a trip a blind pedestrian may wish to be informed of the presence of all marked crossings near a desired route...
April 2017: ACM Transactions on Accessible Computing
https://www.readbyqxmd.com/read/28756782/is-food-store-type-associated-with-the-consumption-of-ultra-processed-food-and-drink-products-in-brazil
#4
Priscila Pereira Machado, Rafael Moreira Claro, Ana Paula Bortoletto Martins, Janaína Calu Costa, Renata Bertazzi Levy
OBJECTIVE: To analyse the association between food store type and the consumption of ultra-processed products in Brazil. DESIGN: Data from the 2008-2009 Household Budget Survey involving a probabilistic sample of 55 970 Brazilian households. Food stores were grouped into nine categories. Foods and drinks were grouped according to characteristics of food processing. The contribution of each food store type to the total energy acquired from each food processing group, and according to quintiles of consumption of ultra-processed products, was estimated...
July 31, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28741645/inflammasome-and-autophagy-regulation-a-two-way-street
#5
Qian Sun, Jie Fan, Timothy R Billiar, Melanie J Scott
Inflammation plays a significant role in protecting hosts against pathogens. Inflammation induced by non-infectious, endogenous agents can be detrimental, and if excessive can result in organ and tissue damage. The inflammasome is a major innate immune pathway that can be activated via both exogenous pathogen-associated molecular patterns (PAMPs) and endogenous damage-associated molecular patterns (DAMPs). Inflammasome activation involves formation and oligomerization of a protein complex including a NOD-like receptor (NLR), an adaptor protein (ASC) and procaspase-1...
July 24, 2017: Molecular Medicine
https://www.readbyqxmd.com/read/28735839/epidemiology-of-proximal-humeral-fractures-a-detailed-survey-of-711-patients-in-a-metropolitan-area
#6
Daniele Passaretti, Vittorio Candela, Pasquale Sessa, Stefano Gumina
BACKGROUND: Literature lacks data concerning several epidemiologic aspects of proximal humeral fractures (PHFs). METHODS: This retrospective study included 711 consecutive patients (209 men, 502 women) who sustained a PHF in the last 3 years. Participants were divided into 2 groups, adults and children. Data regarding age, sex, date, and fracture side were collected. According to the mechanism of injury, we arbitrarily distinguished 7 subgroups. PHFs were classified according to the head-greater-lesser-shaft (HGLS)-Hertel classification and to the Salter-Harris classification using x-ray and computed tomography imaging...
July 20, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28708951/control-of-a-community-outbreak-of-hepatitis-a-in-an-area-of-low-endemicity-wales-2016
#7
J Vaz, C Floyd, B Mason, A G Shankar, H Lewis
Incidence of hepatitis A in Wales is low (average of 0.48/100,000 inhabitants from 2004-2015). We describe a community outbreak of hepatitis A involving 3 schools (primary and secondary) in South Wales between March and June 2016 and reflect on the adequacy of the control measures used. Anyone in South Wales epidemiologically linked to a serological and/or RNA positive confirmed case of hepatitis A during the 15-50 days before onset of symptoms (diarrhoea, vomiting, fever, nausea, AND jaundice, or jaundice-associated symptom) was defined as a case...
July 14, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28678934/-clinical-and-social-vulnerabilities-in-crack-users-according-to-housing-status-a-multicenter-study-in-six-brazilian-state-capitals
#8
MULTICENTER STUDY
Silvia Chwartzmann Halpern, Juliana Nichterwitz Scherer, Vinicius Roglio, Sibele Faller, Anne Sordi, Felipe Ornell, Carla Dalbosco, Flavio Pechansky, Félix Kessler, Lísia von Diemen
The study had the goal to evaluate psychoactive substance use severity, violence, physical and emotional health of crack users who seeks specialized treatment in Psychosocial Care Centers for Alcohol and Drugs (CAPSad) concerning housing status. This is a multicenter cross-sectional study in six Brazilian capitals with 564 crack users categorized into two groups (1) users who have been homeless sometime in life (n = 266) and (2) individuals who have never lived on streets (n = 298). To assess the substance use severity and the characteristics of the individuals, the Addiction Severity Index, 6th version (ASI-6) was used...
July 3, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28673270/built-environment-and-physical-activity-domain-and-activity-specific-associations-among-brazilian-adolescents
#9
Inácio Crochemore Mohnsam da Silva, Adriano Akira Hino, Adalberto Lopes, Ulf Ekelund, Soren Brage, Helen Gonçalves, Ana B Menezes, Rodrigo Siqueira Reis, Pedro Curi Hallal
BACKGROUND: Physical activity is likely to be determined as a complex interplay between personal, interpersonal, and environmental factors. Studying the built environment involves expanding the focus from the individual perspective to a public health one. Therefore, the objetive of this study was to examine the association between the built environment and objectively-measured physical activity among youth. METHODS: Cross-sectional analysis of data from of a Brazilian birth cohort during adolescence...
July 3, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28660163/effective-environmental-factors-on-geographical-distribution-of-traffic-accidents-on-pedestrians-downtown-tehran-city
#10
Ali Moradi, Hamid Soori, Amir Kavousi, Farshid Eshghabadi, Shahrzad Nematollahi, Salahdien Zeini
INTRODUCTION: In most countries, occurrence of traffic causalities is high in pedestrians. The aim of this study is to geographically analyze the traffic casualties in pedestrians in downtown Tehran city. METHODS: The study population consisted of traffic injury accidents in pedestrians occurred during 2015 in Tehran city. Data were extracted from offices of traffic police and municipality. For analysis of environmental factors and site of accidents, ordinary least square regression models and geographically weighted regression were used...
April 2017: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/28657190/repeated-subcutaneous-administrations-of-krokodil-causes-skin-necrosis-and-internal-organs-toxicity-in-wistar-rats-putative-human-implications
#11
Emanuele Amorim Alves, Pedro Brandão, João Filipe Neves, Sara Manuela Cravo, José Xavier Soares, Jean-Paul C Grund, José Alberto Duarte, Carlos M M Afonso, Annibal Duarte Pereira Netto, Félix Carvalho, Ricardo Jorge Dinis-Oliveira
OBJECTIVE: "Krokodil" is the street name for an impure homemade drug mixture used as a cheap substitute for heroin, containing desomorphine as the main opioid. Abscesses, gangrene, thrombophlebitis, limb ulceration and amputations, jaw osteonecrosis, skin discoloration, ulcers, skin infections, and bleeding are some of the typical reported signs in humans. This study aimed to understand the toxicity of krokodil using Wistar male rats as experimental model. METHODS: Animals were divided into seven groups and exposed subcutaneously to NaCl 0...
May 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28655750/aspwood-high-spatial-resolution-transcriptome-profiles-reveal-uncharacterized-modularity-of-wood-formation-in-populus-tremula
#12
David Sundell, Nathaniel R Street, Manoj Kumar, Ewa J Mellerowicz, Melis Kucukoglu, Christoffer Johnsson, Vikash Kumar, Chanaka Mannapperuma, Nicolas Delhomme, Ove Nilsson, Hannele Tuominen, Edouard Pesquet, Urs Fischer, Totte Niittylä, Björn Sundberg, Torgeir R Hvidsten
Trees represent the largest terrestrial carbon sink and a renewable source of ligno-cellulose. There is significant scope for yield and quality improvement in these largely undomesticated species, and efforts to engineer elite varieties will benefit from improved understanding of the transcriptional network underlying cambial growth and wood formation. We generated high-spatial-resolution RNA sequencing data spanning the secondary phloem, vascular cambium, and wood-forming tissues of Populus tremula The transcriptome comprised 28,294 expressed, annotated genes, 78 novel protein-coding genes, and 567 putative long intergenic noncoding RNAs...
July 2017: Plant Cell
https://www.readbyqxmd.com/read/28652316/the-modified-jo-burg-technique-for-securing-intercostal-chest-drains
#13
Daniel J Ablett, L Navaratne, D Chua, C G Streets, N R M Tai
Insertion of an intercostal chest drain (ICD) is a common intervention in the management of either blunt or penetrating thoracic trauma. It is frequently performed by junior medical personnel as an emergency procedure during the initial resuscitation period and often within a stressful environment. Approximately one-fifth of all ICD insertions are associated with complications. In a retrospective review of over 1000 ICD insertions, 7% of the complications observed were due to inadequate fixation, resulting in dislodgement...
June 26, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28643100/perceived-devaluation-and-sti-testing-uptake-among-a-cohort-of-street-involved-youth-in-a-canadian-setting
#14
Mohammad Karamouzian, Jean Shoveller, Huiru Dong, Mark Gilbert, Thomas Kerr, Kora DeBeck
Perceived devaluation has been shown to have adverse effects on the mental and physical health outcomes of people who use drugs. However, the impact of perceived devaluation on sexually transmitted infections (STI) testing uptake among street-involved youth, who face multiple and intersecting stigmas due to their association with drug use and risky sexual practices, has not been fully characterized. Data were obtained between December 2013 and November 2014 from a cohort of street-involved youth who use illicit drugs aged 14-26 in Vancouver, British Columbia...
October 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28639058/geospatial-analysis-of-drug-poisoning-deaths-involving-heroin-in-the-usa-2000-2014
#15
Kathleen Stewart, Yanjia Cao, Margaret H Hsu, Eleanor Artigiani, Eric Wish
We investigate the geographic patterns of drug poisoning deaths involving heroin by county for the USA from 2000 to 2014. The county-level patterns of mortality are examined with respect to age-adjusted rates of death for different classes of urbanization and racial and ethnic groups, while rates based on raw counts of drug poisoning deaths involving heroin are estimated for different age groups and by gender. To account for possible underestimations in these rates due to small areas or small numbers, spatial empirical Baye's estimation techniques have been used to smooth the rates of death and alleviate underestimation when analyzing spatial patterns for these different groups...
August 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28624072/violent-events-on-the-road-risk-perception-of-traffic-related-and-non-traffic-related-situations
#16
Lilian de Oliveira Vilela da Silva, Marilita Gnecco de Camargo Braga
This study aimed at identifying and comparing subjective risk perception regarding two different violent situations in urban roads: traffic accidents (i.e. crashes) and robberies. A robbery consists of subtracting something from someone, while seriously threatening the victim, or using violence. Robberies can be perpetrated either with or without the use of a weapon. This study was carried out in the city of Uberlândia, a medium size city in the state of Minas Gerais, south-east Brazil. A total of 383 people was interviewed at home in two boroughs of Uberlândia, using a questionnaire divided in five parts: a) personal information; b) description of crash involvement; c) description of robbery involvement; d) the chance of being involved in a crash and in a robbery within the next three years; e) willingness to pay for more safety in traffic or for more security against robberies; f) what causes more damage or harm to society, crashes or robberies...
June 14, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28620080/the-sorting-nexin-3-retromer-pathway-regulates-the-cell-surface-localization-and-activity-of-a-wnt-activated-polycystin-channel-complex
#17
Shuang Feng, Andrew J Streets, Vasyl Nesin, Uyen Tran, Hongguang Nie, Marta Onopiuk, Oliver Wessely, Leonidas Tsiokas, Albert C M Ong
Autosomal dominant polycystic kidney disease (ADPKD) is caused by inactivating mutations in PKD1 (85%) or PKD2 (15%). The ADPKD proteins encoded by these genes, polycystin-1 (PC1) and polycystin-2 (PC2), form a plasma membrane receptor-ion channel complex. However, the mechanisms controlling the subcellular localization of PC1 and PC2 are poorly understood. Here, we investigated the involvement of the retromer complex, an ancient protein module initially discovered in yeast that regulates the retrieval, sorting, and retrograde transport of membrane receptors...
June 15, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28619408/children-crossing-streets-the-cognitive-task-of-pedestrians-across-nations
#18
David C Schwebel
BACKGROUND: About 100,000 children die worldwide in pedestrian crashes, more than 90% of whom live in low- and middle-income countries (LMICs). However, most existing research on children's ability to cross the street is conducted in high-income countries (HICs). OBJECTIVE: The present study discusses 4 ways pedestrian behavior in LMICs differs from that in HICs, influencing both children's ability to cross streets safely and adult efforts to train children in pedestrian safety...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28609723/a-rural-urban-comparison-of-privacy-and-confidentiality-concerns-associated-with-providing-sensitive-location-information-in-epidemiologic-research-involving-persons-who-use-drugs
#19
Abby E Rudolph, April M Young, Jennifer R Havens
BACKGROUND: Analyses that link contextual factors with individual-level data can improve our understanding of the "risk environment"; however, the accuracy of information provided by participants about locations where illegal/stigmatized behaviors occur may be influenced by privacy/confidentiality concerns that may vary by setting and/or data collection approach. METHODS: We recruited thirty-five persons who use drugs from a rural Appalachian town and a Mid-Atlantic city to participate in in-depth interviews...
November 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28609379/pediatric-moped-related-injuries-in-the-u-s-from-2002-2014-age-related-comparisons-of-mechanisms-and-outcomes
#20
Nathaniel K Johnson, Brandon M Johnson, Gerene M Denning, Charles A Jennissen
INTRODUCTION: Mopeds are a popular means of transportation, especially in urban areas. However, few studies have investigated moped-related injuries in the United States. This study's goal was to compare the crash mechanisms and injuries suffered in moped-related crashes involving youth versus adults, as well as between younger and older children. METHODS: Descriptive and comparative analyses were performed using National Electronic Injury Surveillance System (NEISS) data and additional variables coded from injury narratives...
June 13, 2017: Journal of Trauma and Acute Care Surgery
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