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"Muscle architecture"

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https://www.readbyqxmd.com/read/27906061/laminin-and-matrix-metalloproteinase-11-regulate-fibronectin-levels-in-the-zebrafish-myotendinous-junction
#1
Molly H Jenkins, Sarah S Alrowaished, Michelle F Goody, Bryan D Crawford, Clarissa A Henry
BACKGROUND: Remodeling of the extracellular matrix (ECM) regulates cell adhesion as well as signaling between cells and their microenvironment. Despite the importance of tightly regulated ECM remodeling for normal muscle development and function, mechanisms underlying ECM remodeling in vivo remain elusive. One excellent paradigm in which to study ECM remodeling in vivo is morphogenesis of the myotendinous junction (MTJ) during zebrafish skeletal muscle development. During MTJ development, there are dramatic shifts in the primary components comprising the MTJ matrix...
May 2, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27896273/relationships-between-muscle-architecture-of-rectus-femoris-and-functional-parameters-of-knee-motion-in-adults-with-down-syndrome
#2
Maria Stella Valle, Antonino Casabona, Marco Micale, Matteo Cioni
This study was designed to measure in vivo muscle architecture of the rectus femoris in adults with Down syndrome, testing possible relationships with functional parameters of the knee motion. Ten adults with Down syndrome and ten typically developed participated in the study. Pennation angle and thickness of the rectus femoris and subcutaneous layer of the thigh were measured via ultrasound imaging. Knee kinematics and electromyographic activity of the rectus femoris were recorded during free leg dropping...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27894277/human-limb-skeletal-muscle-wasting-and-architectural-remodeling-during-five-to-ten-days-intubation-and-ventilation-in-critical-care-an-observational-study-using-ultrasound
#3
Peter Turton, Richard Hay, Jonathon Taylor, Jamie McPhee, Ingeborg Welters
BACKGROUND: Critically ill patients frequently suffer muscle weakness whilst in critical care. Ultrasound can reliably track loss of muscle size, but also quantifies the arrangement of the muscle fascicles, known as the muscle architecture. We sought to measure both pennation angle and fascicle length, as well as tracking changes in muscle thickness in a population of critically ill patients. METHODS: On days 1, 5 and 10 after admission to critical care, muscle thickness was measured in ventilated critically ill patients using bedside ultrasound...
November 29, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27888744/bilateral-changes-in-muscle-architecture-of-physically-active-people-with-chronic-stroke-a-quantitative-muscle-ultrasound-study
#4
Frank Berenpas, Anne-Marieke Martens, Vivian Weerdesteyn, Alexander C Geurts, Nens van Alfen
OBJECTIVE: Changes in muscle architecture after stroke are usually assessed by investigating inter-limb differences. As a result bilateral changes of muscle architecture might be missed. Our aim was to investigate whether bilateral architectural changes in skeletal muscle can be detected in chronic, physically active stroke patients using quantitative muscle ultrasound (QMUS). METHODS: Twenty-eight patients (mean time since stroke 5.2years, median Brunnström stage 4) were recruited...
November 11, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27825160/pathophysiology-of-volumetric-muscle-loss-injury
#5
Benjamin T Corona, Joseph C Wenke, Catherine L Ward
Volumetric muscle loss (VML) injuries are prevalent in civilian and military trauma patients and are known to impart chronic functional deficits. The frank loss of muscle tissue that defines VML injuries is beyond the robust reparative and regenerative capacities of mammalian skeletal muscle. Given the nature of VML injuries, there is a clear need to develop therapies that promote de novo regeneration of skeletal muscle fibers, which can integrate with the remaining musculature and restore muscle strength. However, the pathophysiology of VML injuries is not completely defined, and, therefore, there may be other opportunities to improve functional outcomes other than de novo regeneration...
2016: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/27798092/igf-1-gh-axis-enhances-losartan-treatment-in-lama2-related-muscular-dystrophy
#6
Anthony Accorsi, Ajay Kumar, Younghwa Rhee, Alex Miller, Mahasweta Girgenrath
As the complexities of dystrophic pathology have been elucidated over the last few years, it has become increasingly clear that primary monogenetic defects result in multiple secondary pathologies capable of autonomously driving disease progression. Consequently, single-mode therapies fail to comprehensively ameliorate all aspects of pathology. Lama2-related muscular dystrophy (MDC1A) is a devastating congenital muscular dystrophy caused by mutations in the LAMA2 gene that results in multi-faceted secondary pathologies that include inflammation, fibrosis, apoptosis, and necrosis leading to severe muscle weakness and minimal postnatal growth...
October 24, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/27779826/mystacial-whisker-layout-and-musculature-in-the-guinea-pig-cavia-porcellus-a-social-diurnal-mammal
#7
Robyn A Grant, Mariane G Delaunay, Sebastian Haidarliu
All mammals (apart from apes and humans) have whiskers that make use of a similar muscle arrangement. Whisker specialists, such as rats and mice, tend to be nocturnal and arboreal, relying on their whisker sense of touch to guide exploration around tree canopies at night. As such, nocturnal arboreal rodents have many whiskers that are organised into a grid-like pattern, and moved using a complex array of muscles. Indeed, most arboreal, nocturnal mammals tend to have specialised whiskers that are longer and arranged in a dense, regular grid, compared to terrestrial, diurnal mammals...
October 25, 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/27676994/muscle-lengthening-and-structural-changes-in-the-muscle-tendon-complex-of-triceps-surae-after-1%C3%A2-year-of-rehabilitation-including-a-daily-self-stretch-program-in-patients-with-chronic-hemiparesis
#8
Maud Pradines, Ingrid Masson, Raphaël Portero, Caroline Giroux, Jean-Michel Gracies
OBJECTIVE: To explore changes in muscle architectural parameters of the muscle-tendon unit of soleus and medial gastrocnemius (GM) in patients with chronic hemiparesis, after 1 year of rehabilitation. MATERIAL/PATIENTS AND METHODS: In this prospective study, 20 chronic hemiparetic patients (8W, mean age: 56 [12], time since lesion 9 [8]) were evaluated. Muscle architectural parameters including muscle fascicle length, pennation angle, thickness, tendon and muscle belly lengths were evaluated in vivo using ultrasonography in passive condition (verified by electromyographic recording) in a seated patient with ankle, knee and hip on the paretic side at 90°...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27660293/restoration-of-hydrogen-sulfide-production-in-diabetic-mice-improves-reparative-function-of-bone-marrow-cells
#9
Zhongjian Cheng, Venkata Naga Srikanth Garikipati, Emily Nickoloff, Chunlin Wang, David J Polhemus, Jibin Zhou, Cynthia Benedict, Mohsin Khan, Suresh K Verma, Joseph E Rabinowitz, David Lefer, Raj Kishore
BACKGROUND: Bone marrow cell (BMC)-based treatment for critical limb ischemia in diabetic patients yielded a modest therapeutic effect resulting from cell dysfunction. Therefore, approaches that improve diabetic stem/progenitor cell functions may provide therapeutic benefits. Here, we tested the hypothesis that restoration of hydrogen sulfide (H2S) production in diabetic BMCs improves their reparative capacities. METHODS: Mouse BMCs were isolated by density-gradient centrifugation...
November 8, 2016: Circulation
https://www.readbyqxmd.com/read/27659479/effects-of-high-intensity-interval-cycling-performed-after-resistance-training-on-muscle-strength-and-hypertrophy
#10
S Tsitkanou, K Spengos, A-N Stasinaki, N Zaras, G Bogdanis, G Papadimas, G Terzis
Aim of the study was to investigate whether high-intensity interval cycling performed immediately after resistance training would inhibit muscle strength increase and hypertrophy expected from resistance training per se. Twenty-two young men were assigned into either resistance training (RE; N = 11) or resistance training plus high-intensity interval cycling (REC; N = 11). Lower body muscle strength and rate of force development (RFD), quadriceps cross-sectional area (CSA) and vastus lateralis muscle architecture, muscle fiber type composition and capillarization, and estimated aerobic capacity were evaluated before and after 8 weeks of training (2 times per week)...
September 23, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/27604399/behavior-of-human-gastrocnemius-muscle-fascicles-during-ramped-submaximal-isometric-contractions
#11
Martin E Héroux, Peter W Stubbs, Robert D Herbert
Precise estimates of muscle architecture are necessary to understand and model muscle mechanics. The primary aim of this study was to estimate continuous changes in fascicle length and pennation angle in human gastrocnemius muscles during ramped plantar flexor contractions at two ankle angles. The secondary aim was to determine whether these changes differ between proximal and distal fascicles. Fifteen healthy subjects performed ramped contractions (0-25% MVC) as ultrasound images were recorded from the medial (MG, eight sites) and lateral (LG, six sites) gastrocnemius muscle with the ankle at 90° and 120° (larger angles correspond to shorter muscle lengths)...
September 2016: Physiological Reports
https://www.readbyqxmd.com/read/27584491/changes-in-muscle-architecture-and-explosive-ability-in-collegiate-volleyball-players-throughout-a-competitive-season-2880-board-3-june-3-1-00-pm-3-00-pm
#12
Caleb D Bazyler, Timothy J Suchomel, Christopher J Sole, Satoshi Mizuguchi, Michael H Stone
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27575250/changes-in-muscle-architecture-explosive-ability-and-track-and-field-throwing-performance-throughout-a-competitive-season-and-following-a-taper
#13
Caleb D Bazyler, Satoshi Mizuguchi, Alex P Harrison, Kimitake Sato, Ashley A Kavanaugh, Brad H DeWeese, Michael H Stone
The purpose of this study was to examine the effects of an overreach and taper on measures of muscle architecture, jumping, and throwing performance in Division I collegiate throwers preparing for conference championships. Six collegiate track and field throwers (3 hammer, 2 discus, 1 javelin) trained for 12 weeks using a block-periodization model culminating with a one week overreach followed by a 3 week taper (ORT). Session rating of perceived exertion training load (RPETL) and strength training volume-load times bar displacement (VLd) were recorded weekly...
August 26, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27518505/regulation-of-skeletal-muscle-myoblast-differentiation-and-proliferation-by-pannexins
#14
Stéphanie Langlois, Kyle N Cowan
Pannexins are newly discovered channels that are now recognized as mediators of adenosine triphosphate release from several cell types allowing communication with the extracellular environment. Pannexins have been associated with various physiological and pathological processes including apoptosis, inflammation, and cancer. However, it is only recently that our work has unveiled a role for Pannexin 1 and Pannexin 3 as novel regulators of skeletal muscle myoblast proliferation and differentiation. Myoblast differentiation is an ordered multistep process that includes withdrawal from the cell cycle and the expression of key myogenic factors leading to myoblast differentiation and fusion into multinucleated myotubes...
August 13, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27484001/exercise-strategies-to-protect-against-the-impact-of-short-term-reduced-physical-activity-on-muscle-function-and-markers-of-health-in-older-men-study-protocol-for-a-randomised-controlled-trial
#15
Oliver J Perkin, Rebecca L Travers, Javier T Gonzalez, James E Turner, Fiona Gillison, Cassie Wilson, Polly M McGuigan, Dylan Thompson, Keith A Stokes
BACKGROUND: Muscles get smaller and weaker as we age and become more vulnerable to atrophy when physical activity is reduced or removed. This research is designed to investigate the potentially protective effects of two separate exercise strategies against loss in skeletal muscle function and size, and other key indices of health, following 14 days of reduced physical activity in older men. METHODS: Three groups of 10 older men (aged 65-80 years) will undertake 2 weeks of reduced activity by decreasing daily steps from more than 3500 to less than 1500 (using pedometers to record step count)...
2016: Trials
https://www.readbyqxmd.com/read/27457913/neuromuscular-responses-to-short-term-resistance-training-with-traditional-and-daily-undulating-periodization-in-adolescent-elite-judoka
#16
Boris Ullrich, Thiemo Pelzer, Sergio Oliveira, Mark Pfeiffer
Ullrich, B, Pelzer, T, Oliveira, S, and Pfeiffer, M. Neuromuscular responses to short-term resistance training with traditional and daily undulating periodization in adolescent elite judoka. J Strength Cond Res 30(8): 2083-2099, 2016-The influence of different periodization models on neuromuscular outcomes after short-term strength training periods has not been examined in adolescent athletes. Eleven elite judoka (age: 14.8 ± 0.6 years, height: 163.2 ± 7.5 cm, body mass: 57.3 ± 11.1 kg, 5 boys/6 girls, and strength training experience: 2...
August 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27449490/muscle-architecture-and-torque-production-in-stroke-survivors-an-observational-study
#17
Caroline P Dias, Bruno Freire, Natália B A Goulart, Eduardo S Onzi, Jefferson Becker, Irenio Gomes, Adamantios Arampatzis, Marco A Vaz
OBJECTIVE: Spasticity poststroke leads to muscle weakness and soft tissue contracture, however, it is not clear how muscle properties change due this motor neural disorder. The purpose was to compare medial gastrocnemius muscle architecture and mechanical properties of the plantarflexor muscles between stroke survivors with spasticity and healthy subjects. METHODS: The study included 15 stroke survivors with ankle spasticity and 15 healthy subjects. An isokinetic dynamometer was used for the evaluation of maximal isometric plantarflexor torque and images of the medial gastrocnemius muscle were obtained using ultrasonography...
July 22, 2016: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/27361127/the-influence-of-muscle-architecture-on-the-age-related-changes-in-maximal-and-rapid-strength-2491-board-14-june-3-9-30-am-11-00-am
#18
Gena R Gerstner, Eric D Ryan, Brennan J Thompson, Joseph G Rosenberg, Eric J Sobolewski, Michael J Scharville
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27360139/relationships-between-muscle-architecture-and-measures-of-strength-and-power-in-collegiate-volleyball-players-996-board-312-june-1-3-30-pm-5-00-pm
#19
Jacob R Goodin, Caleb D Bazyler, Satoshi Mizuguchi, Michael H Stone
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27343167/reduced-skeletal-muscle-satellite-cell-number-alters-muscle-morphology-after-chronic-stretch-but-allows-limited-serial-sarcomere-addition
#20
Matthew C Kinney, Sudarshan Dayanidhi, Peter B Dykstra, John J McCarthy, Charlotte A Peterson, Richard L Lieber
INTRODUCTION: Muscles add sarcomeres in response to stretch, presumably to maintain optimal sarcomere length. Clinical evidence from patients with cerebral palsy (CP), who have both decreased serial sarcomere number and reduced satellite cells (SCs), suggests a hypothesis that SCs may be involved in sarcomere addition. METHODS: A transgenic Pax7-DTA mouse model underwent conditional SC depletion, and their soleii were then stretch-immobilized to assess their capacity for sarcomere addition...
June 24, 2016: Muscle & Nerve
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