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S Longo, M Palacios, M E Tinti, J Siri, J I de Brahi, M C Cabrera Shulmeyer
We describe a case of intraoperative cardiac trombosis during orthotopic liver transplant surgery that resulted in intraoperative death. By using transesophageal echocardiography, the cause of the descompensation of the patient could be determined and the mechanism of trombus migration from thrombi from the venous circulation to the left heart was accurately observed.
March 20, 2018: Revista Española de Anestesiología y Reanimación
Luis del Carpio-Orantes, Chantall Citlally Martínez-Anaya, Elías Bonilla-Casas
The present document is the report of a case of a very rare clinical entity, which presents with acute multiorganic failure after a thrombotic storm related to antiphospholipid antibodies, the so-called catastrophic antiphospholipid syndrome, which began as a recurrent picture of mesenteric thrombosis, with a previous history of venous insufficiency and distal ulcers probably associated with an unidentified antiphospholipid; deserving management in intensive care and the consultation by the world expert, Dr...
2017: Gaceta Médica de México
Jorge Acuña-Valerio, Marco Antonio Peña-Duque, Álvaro Contreras-Villaseñor
Antiphospholipid antibody syndrome is a heterogeneous clinical and biochemical entity. We present the case of a young male with history of venous thromboembolism. This time he presents because of chest ischemic pain associated with ST segment elevation. He was taken to the cath lab to perform a primary percutaneous coronary intervention and a total occlusion of the left anterior descending artery was noted. Successful thrombus aspiration was performed. No stent was deployed. He was taken to the cath lab for a second look angiography and no atherosclerotic lesions were observed, which was confirmed by intravascular ultrasound...
2017: Gaceta Médica de México
Gregorio Campos-Cabrera, Virginia Campos-Cabrera, Salvador Campos-Cabrera, José-Luis Campos-Villagómez, Alejandra Romero-González
Myeloproliferative neoplasms are chronic disorders of clonal hematopoietic stem cells, characterized by an overproduction of functional granulocytes, red blood cells and / or platelets, and one of the major complications is the occurrence of venous and arterial thrombotic problems caused by increased platelet aggregation and thrombin generation. In this study 11 cases of primary myelofibrosis (PM) were evaluated and 2 debuted with splanchnic venous thrombosis (SVT); so after seeing the results of this study and of world literature, it is suggested that in patients with SVT, diagnostic methods for PM like the JAK2V617F mutation should be included...
2017: Gaceta Médica de México
Paola Saracco, Rossana Bagna, Chiara Gentilomo, Mariella Magarotto, Alice Viano, Federica Magnetti, Paola Giordano, Matteo Luciani, Angelo Claudio Molinari, Agnese Suppiej, Luca Antonio Ramenghi, Paolo Simioni
OBJECTIVE: To evaluate clinical data and associated risk conditions of noncerebral systemic venous thromboembolism (VT), arterial thromboembolism (AT), and intracardiac thromboembolism (ICT) in neonates. STUDY DESIGN: Data analysis of first systemic thromboembolism occurring in 75 live neonates (0-28 days), enrolled in the Italian Registry of Pediatric Thrombosis from neonatology centers between January 2007 and July 2013. RESULTS: Among 75 events, 41 (55%) were VT, 22 (29%) AT, and 12 (16%) ICT; males represented 65%, and 71% were preterm...
April 2016: Journal of Pediatrics
Fatma Yildirim, İskender Kara, Hızır Okuyan, Adnan Abaci, Melda Turkoglu, Gülbin Aygencel
A 54-year-old man had undergone to percutaneous coronary intervention (PCI) and two stents were placed to left anterior coronary artery and circumflex artery. Low molecular weight heparin (LMWH) together with ticagrelor 90 mg twice a day and acetylsalicylic acid (Aspirin) were started after PCI due to high risk of stent trombosis. On the fourth day of patient's follow-up in the intensive care unit (ICU), bloody secretion was started from endotracheal tube. Hemoglobin dropping, bilateral infiltration on the chest X-ray and bleeding from lung were diagnosed as diffuse alveolar hemorrhage (DAH)...
January 19, 2016: Clinical Respiratory Journal
Ramón Montes, Elisabet Guruceaga, José R González-Porras, Joan C Reverter, Pascual Marco, Elena Pina, José A Páramo, José Hermida, Ramón Lecumberri
OBJECTIVE: The aim of this study was to assess differences in the gene expression profile of peripheral blood cells between patients with early recurrent thrombosis vs. patients without recurrent events after withdrawal of anticoagulant therapy for a first episode of unprovoked deep vein thrombosis (uDVT), to identify novel predictors of recurrence. METHODS: In the discovery population (N = 32), a microarray RNA assay followed by RT-PCR confirmation were performed...
August 2016: European Journal of Haematology
Agnese Suppiej, Chiara Gentilomo, Paola Saracco, Stefano Sartori, Manuela Agostini, Rossana Bagna, Bianca Bassi, Paola Giordano, Massimo Grassi, Andrea Guzzetta, Donatella Lasagni, Matteo Luciani, Angelo C Molinari, Antonella Palmieri, Maria Caterina Putti, Luca Antonelli Ramenghi, Lidia Luciana Rota, Domenico Sperlì, Anna Maria Laverda, Paolo Simioni
Data from large case series of children with cerebral thrombotic events are pivotal to improve prevention, early recognition and treatment of these conditions. The Italian Registry of Pediatric Thrombosis (R. I. T. I.) was established in 2007 by a multidisciplinary team, aiming for a better understanding of neonatal and paediatric thrombotic events in Italy and providing a preliminary source of data for the future development of specific clinical trials and diagnostic-therapeutic protocols. We analysed data relative to the paediatric cerebral thrombotic events of the R...
June 2015: Thrombosis and Haemostasis
A F Vanin, L V Adamian, E N Burgova, N A Tkachev
Exogenous dinitrosyl iron complexes (DNIC) with thiol-containing ligands as NO and NO+ donors are capable of exerting both regulatory and cytotoxic effects on diverse biological processes similarly to those characteristic of endogenous nitric oxide. Regulatory activity of DNIC (vasodilation, hypotension, trombosis suppression, red blood cell elasticity increasing, skin wound healing acceleration, penile erection inducing, etc) is determined by their capacity of NO and NO+ transfer to biological targets of the latter (hemo- and thiol-containing proteins, respectively) due to higher affinity of the proteins for NO and NO+ than that of DNIC...
July 2014: Biofizika
Juan G Córdoba-Soriano, Rishi Puri, Ignacio Amat-Santos, Henrique B Ribeiro, Omar Abdul-Jawad Altisent, María del Trigo, Jean-Michel Paradis, Eric Dumont, Marina Urena, Josep Rodés-Cabau
INTRODUCTION AND OBJECTIVES: Despite the rapid global uptake of transcatheter aortic valve implantation, valve trombosis has yet to be systematically evaluated in this field. The aim of this study was to determine the clinical characteristics, diagnostic criteria, and treatment outcomes of patients diagnosed with valve thrombosis following transcatheter aortic valve implantation through a systematic review of published data. METHODS: Literature published between 2002 and 2012 on valve thrombosis as a complication of transcatheter aortic valve implantation was identified through a systematic electronic search...
March 2015: Revista Española de Cardiología
Juan Carlos Hernández Boluda
No abstract text is available yet for this article.
March 15, 2015: Medicina Clínica
Carlos Grande García, Rafael Martínez Martínez, David Valcarcel Ferreiras
No abstract text is available yet for this article.
November 7, 2014: Medicina Clínica
Z Jabiry-Zieniewicz, F A Dabrowski, B Suchońska, R Kowalczyk, E Nowacka, B Kociszewska-Najman, B Pietrzak, P Malkowski, M Wielgos
AIM: Retrospective analysis of the course of pregnancy, labor and mode of anesthesia in women with portal hypertension and esophageal varices induced by portal vein thrombosis. MATERIAL: From 2000 to 2012 seven pregnant were admitted. None had liver transplantation (Ltx), the varicose have been in the 1st stage. Each of them has been consulted by the obstetrician, transplant surgeon and anesthetist. The patient condition during pregnancy, labor and postpartum period was analyzed...
January 2015: Journal of Maternal-fetal & Neonatal Medicine
E Alegria-Barrero, N Foin, A C Lindsay, M Paulo, P Hei Chan, D Syrseloudis, N Viceconte, R Martos, K Beatt, C Di Mario
Although provisional T-stenting with stenting of the main branch and optional side branch stenting is nowadays the default strategy generally preferred for simple bifurcation lesions, percutaneous coronary intervention (PCI) of complex true bifurcation lesions remains a difficult task to achieve also with modern second generation drug eluting stents. Treatment of complex bifurcational lesions is not only more time consuming but can lead to significantly higher rate of periprocedural myocardial infarction and late estenosis, stent thrombosis and target lesion revascularization...
October 2013: Minerva Cardioangiologica
Jose R Gonzalez-Porras, Fernando Escalante, Emilia Pardal, Magdalena Sierra, Luis J Garcia-Frade, Santiago Redondo, Maryam Arefi, Carlos Aguilar, Fernando Ortega, Erik de Cabo, Rosa M Fisac, Oscar Sanz, Carmen Esteban, Ignacio Alberca, Mercedes Sanchez-Barba, Maria T Santos, Abel Fernandez, Tomas J Gonzalez-Lopez
AIM: Few studies specifically focus on elderly splenectomized immune thrombocytopenia (ITP) patients. Older patients with ITP and excellent health are often excluded from surgery splenectomy. We aimed to compare the safety and efficacy of splenectomy in elderly and non-elderly ITP patients and to examine the effect of age on therapeutic response. MATERIAL AND METHODS: We carried out a retrospective analysis of a series of 218 patients who had undergone splenectomy for ITP...
September 2013: European Journal of Haematology
A P Trevizol, A I David, E T Yamashita, R A Pecora, L A D'Albuquerque
BACKGROUND: Intestinal/multivisceral transplantation (IT/MVT) is the gold standard treatment for patients with intestinal failure and complications related to total parenteral nutrition, gastrointestinal inoperable indolent tumors, or diffuse portal trombosis. Currently, the reported 1-year patient survival rate is around 80%, similar to other solid organ abdominal transplantations. Unfortunately, the patient survival decreases after the first year with the 5-year rate not close to 70% yet...
April 2013: Transplantation Proceedings
Luis A Ramón, Aitana Braza-Boïls, Juan Gilabert, Melitina Chirivella, Francisco España, Amparo Estellés, Juan Gilabert-Estellés
STUDY QUESTION: Which is the role of microRNAs (miRNAs) related to several angiogenesis regulators such as VEGF-A (Vascular endothelial growth factor-A) and TSP-1 (Thrombospondin-1) in endometrial cancer? SUMMARY ANSWER: A dysregulated expression of miRNAs related to angiogenesis and an increase in the VEGF-A levels were observed in endometrial cancer in comparison with control. The different expression of miRNAs could modulate the expression of angiogenic and antiangiogenic factors, which may play an important role in the pathogenesis of endometrial cancer...
October 2012: Human Reproduction
N Al Hajjar, D Crişan, M Grigorescu, P Boruah
Liver abscess is a rare complication of sigmoid diverticulitis and must be considered within the differential diagnosis. We report a case of a male patient, age 42, admitted to our hospital with chief complaints of a dull pain in upper right abdominal quadrant, fever, weakness, diarrhoea and weight loss of approximately 3 weeks duration. Physical examination on initial work-up revealed tenderness on palpation in upper right abdomen, and left iliac fosa and a 39 degrees C fever. Biochemistry showed marked inflammatory syndrome, leukocitosis, increased level of platelets, altered liver function...
March 2012: Chirurgia
L Voltolini, C Rapicetta, L Luzzi, P Paladini, C Ghiribelli, S Scolletta, M Fineschi, G Gotti
AIM: Recent studies have reported a high incidence of perioperative in-stent trombosis with myocardial infarction (MI), in patients undergoing non-cardiac surgery, early after coronary angioplasty and stenting. The short and long-term results of surgery for non-small cell lung cancer (NSCLC) after prophylatic coronary angioplasty and stenting were analyzed. METHODS: Prospective collected data were examined for postoperative complications and long-term survival in 16 consecutive patients who underwent mayor lung resection for NSCLC after prophylactic coronary angioplasty and stenting for significant coronary artery disease , from 2001 to 2008...
February 2012: Minerva Chirurgica
José Ramón de Berrazueta Fernández
Acute Coronary Syndrome (ACS) are classified by the mechanisms of thrombosis that induce the complete of partial occlusion of coronary artery, with two tipes of ST changes in ECG. ACS with ST segment elevation (ACSSTE) is induced by a completed thrombotic occlusion by a red thrombus, it need a rapid and complete restoration of coronary artery blood flow with myocardial reperfusion in the first six hours after starting with pain. This is the mechanism by which reperfusion therapy reduces morbidity and mortality...
2010: Anales de la Real Academia Nacional de Medicina
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