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seroprevalence and dengue

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https://www.readbyqxmd.com/read/27926925/dengue-in-the-middle-east-and-north-africa-a-systematic-review
#1
John M Humphrey, Natalie B Cleton, Chantal B E M Reusken, Marshall J Glesby, Marion P G Koopmans, Laith J Abu-Raddad
BACKGROUND: Dengue virus (DENV) infection is widespread and its disease burden has increased in past decades. However, little is known about the epidemiology of dengue in the Middle East and North Africa (MENA). METHODOLOGY / PRINCIPAL FINDINGS: Following Cochrane Collaboration guidelines and reporting our findings following PRISMA guidelines, we systematically reviewed available records across MENA describing dengue occurrence in humans (prevalence studies, incidence studies, and outbreak reports), occurrence of suitable vectors (Aedes aegypti and Aedes albopictus), and DENV vector infection rates...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27898668/the-long-term-safety-public-health-impact-and-cost-effectiveness-of-routine-vaccination-with-a-recombinant-live-attenuated-dengue-vaccine-dengvaxia-a-model-comparison-study
#2
Stefan Flasche, Mark Jit, Isabel Rodríguez-Barraquer, Laurent Coudeville, Mario Recker, Katia Koelle, George Milne, Thomas J Hladish, T Alex Perkins, Derek A T Cummings, Ilaria Dorigatti, Daniel J Laydon, Guido España, Joel Kelso, Ira Longini, Jose Lourenco, Carl A B Pearson, Robert C Reiner, Luis Mier-Y-Terán-Romero, Kirsten Vannice, Neil Ferguson
BACKGROUND: Large Phase III trials across Asia and Latin America have recently demonstrated the efficacy of a recombinant, live-attenuated dengue vaccine (Dengvaxia) over the first 25 mo following vaccination. Subsequent data collected in the longer-term follow-up phase, however, have raised concerns about a potential increase in hospitalization risk of subsequent dengue infections, in particular among young, dengue-naïve vaccinees. We here report predictions from eight independent modelling groups on the long-term safety, public health impact, and cost-effectiveness of routine vaccination with Dengvaxia in a range of transmission settings, as characterised by seroprevalence levels among 9-y-olds (SP9)...
November 2016: PLoS Medicine
https://www.readbyqxmd.com/read/27891337/high-seroprevalence-of-dengue-virus-infection-in-blood-donors-from-delhi-a-single-centre-study
#3
Pragya Ranjan, Vidhya Natarajan, Meenu Bajpai, Ekta Gupta
INTRODUCTION: The risk of transfusion transmitted dengue has been increasingly recognized. Blood donors in an endemic area like Delhi may serve as a potential vehicle for transmission of the infection. Moreover, prevalence of infection in them would be representative of the true picture of dengue in a population. AIM: To determine the prevalence of dengue virus infection in blood donors in a tertiary care centre. MATERIALS AND METHODS: A total of 200 blood donors were recruited in the study after obtaining informed consent in the Institute of Liver and Biliary Sciences, New Delhi in July and August 2012...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27887591/a-prospective-cohort-study-to-assess-seroprevalence-incidence-knowledge-attitudes-and-practices-willingness-to-pay-for-vaccine-and-related-risk-factors-in-dengue-in-a-high-incidence-setting
#4
Ruth Aralí Martínez-Vega, Alfonso J Rodriguez-Morales, Yalil Tomás Bracho-Churio, Mirley Enith Castro-Salas, Fredy Galvis-Ovallos, Ronald Giovanny Díaz-Quijano, María Lucrecia Luna-González, Jaime E Castellanos, José Ramos-Castañeda, Fredi Alexander Diaz-Quijano
BACKGROUND: Dengue is one of the most important vector-borne diseases in the world, causing significant morbidity and economic impact. In Colombia, dengue is a major public health problem. Departments of La Guajira, Cesar and Magdalena are dengue endemic areas. The objective of this research is to determine the seroprevalence and the incidence of dengue virus infection in the participating municipalities from these Departments, and also establish the association between individual and housing factors and vector indices with seroprevalence and incidence...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27879463/a-tale-of-two-flaviviruses-a-seroepidemiological-study-of-dengue-virus-and-west-nile-virus-transmission-in-the-ouest-and-sud-est-departments-of-haiti
#5
Thomas A Weppelmann, Alexandra Burne, Michael E von Fricken, Maha A Elbadry, Madsen Beau De Rochars, Jacques Boncy, Bernard A Okech
Though plans to eliminate malaria from the island of Hispaniola have recently received much attention, arbovirus surveillance continues to be largely neglected in Haiti. To support surveillance efforts and encourage vector-control strategies, a cross-sectional study of dengue virus (DENV) and West Nile virus (WNV) transmission was conducted using standard seroepidemiological methods. Blood samples (N = 673) were collected from 278 males and 395 females from three locations in the Ouest and Sud-Est Departments of Haiti...
November 22, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27825949/dengue-serotype-specific-seroprevalence-among-5-to-10-year-old-children-in-india-a-community-based-cross-sectional-study
#6
Suneela Garg, Anita Chakravarti, Ritesh Singh, N R Ramesh Masthi, Ram Chandra Goyal, Guru Rajesh Jammy, Enakshi Ganguly, Nandini Sharma, M M Singh, Germano Ferreira, Annick Moureau, Sujeet Ojha, Joshua Nealon
BACKGROUND: Dengue surveillance data in India are limited and probably substantially underestimate the burden of disease. A community-based study was undertaken to assess the prevalence of dengue-specific immunoglobulin G (IgG) antibodies in children across India and to examine historical dengue exposure rates. Potential associations between socio-economic factors and dengue seroprevalence were also assessed (registered at ctri.nic.in: CTRI/2011/12/002243). METHODS: A convenience sample of 2609 healthy children aged 5-10 years was enrolled; these children were registered at or were living in the vicinity of eight centres located at six geographically distinct sites across India...
November 4, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27821884/measuring-haitian-children-s-exposure-to-chikungunya-dengue-and-malaria
#7
Mathieu Jp Poirier, Delynn M Moss, Karla R Feeser, Thomas G Streit, Gwong-Jen J Chang, Matthew Whitney, Brandy J Russell, Barbara W Johnson, Alison J Basile, Christin H Goodman, Amanda K Barry, Patrick J Lammie
OBJECTIVE: To differentiate exposure to the newly introduced chikungunya virus from exposure to endemic dengue virus and other pathogens in Haiti. METHODS: We used a multiplex bead assay to detect immunoglobulin G (IgG) responses to a recombinant chikungunya virus antigen, two dengue virus-like particles and three recombinant Plasmodium falciparum antigens. Most (217) of the blood samples investigated were collected longitudinally, from each of 61 children, between 2011 and 2014 but another 127 were collected from a cross-sectional sample of children in 2014...
November 1, 2016: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/27792777/unsuspected-dengue-as-a-cause-of-acute-febrile-illness-in-children-and-adults-in-western-nicaragua
#8
Megan E Reller, Aravinda M de Silva, Jeremy J Miles, Ramesh S Jadi, Anne Broadwater, Katie Walker, Christopher Woods, Orlando Mayorga, Armando Matute
BACKGROUND: Dengue is an emerging infectious disease of global significance. Suspected dengue, especially in children in Nicaragua's heavily-urbanized capital of Managua, has been well documented, but unsuspected dengue among children and adults with undifferentitated fever has not. METHODOLOGY/PRINCIPAL FINDINGS: To prospectively study dengue in semi-urban and rural western Nicaragua, we obtained epidemiologic and clinical data as well as acute and convalescent sera (2 to 4 weeks after onset of illness) from a convenience sample (enrollment Monday to Saturday daytime to early evening) of consecutively enrolled patients (n = 740) aged ≥ 1 years presenting with acute febrile illness...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27731556/dengue-and-chikungunya-virus-co-infections-the-inside-story
#9
Vikram Londhey, Sachee Agrawal, Nilima Vaidya, Seema Kini, J S Shastri, Sujatha Sunil
INTRODUCTION: There have been various studies from India describing the acute presentation and the long-term sequalae of Chikungunya (CHIKV) infection. However, there are very few studies discussing the Chikungunya-Dengue (DENV) co-infection from Western India. The present project was undertaken to study the clinical features of Dengue and Chikungunya co-infection and compare with Chikungunya mono-infection; correlate the clinical findings with seroprevalence and molecular identification of Dengue and Chikungunya using IgM ELISA and RTPCR...
March 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27538986/rural-urban-comparisons-of-dengue-seroprevalence-in-malaysia
#10
Cheng Hoon Chew, Yuan Liang Woon, Faridah Amin, Tassha H Adnan, Asmah Hani Abdul Wahab, Zul Edzhar Ahmad, Mohd Adam Bujang, Abdul Muneer Abdul Hamid, Rahman Jamal, Wei Seng Chen, Chee Peng Hor, Lena Yeap, Ling Ping Hoo, Pik Pin Goh, Teck Onn Lim
BACKGROUND: Each year an estimated 390 million dengue infections occur worldwide. In Malaysia, dengue is a growing public health concern but estimate of its disease burden remains uncertain. We compared the urban-rural difference of dengue seroprevalence and determined age-specific dengue seroprevalence in Malaysia. METHODS: We undertook analysis on 11,821 subjects from six seroprevalence surveys conducted in Malaysia between 2001 and 2013, which composed of five urban and two rural series...
2016: BMC Public Health
https://www.readbyqxmd.com/read/27399793/estimating-dengue-transmission-intensity-from-case-notification-data-from-multiple-countries
#11
Natsuko Imai, Ilaria Dorigatti, Simon Cauchemez, Neil M Ferguson
BACKGROUND: Despite being the most widely distributed mosquito-borne viral infection, estimates of dengue transmission intensity and associated burden remain ambiguous. With advances in the development of novel control measures, obtaining robust estimates of average dengue transmission intensity is key for assessing the burden of disease and the likely impact of interventions. METHODOLOGY/PRINCIPLE FINDINGS: We estimated the force of infection (λ) and corresponding basic reproduction numbers (R0) by fitting catalytic models to age-stratified incidence data identified from the literature...
July 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27365916/chikungunya-fever-among-patients-with-acute-febrile-illness-attending-a-tertiary-care-hospital-in-mumbai
#12
Lata Baswanna Galate, Sachee R Agrawal, Jayanthi S Shastri, Vikram Londhey
BACKGROUND: Chikungunya fever (CHIK) is an arboviral disease. Dengue fever (DENG) and CHIK are indistinguishable clinically and need to be differentiated by laboratory investigations. PURPOSE: This study aimed at estimating the seroprevalence of CHIK mono-infection and CHIK and DENG dual infection in suspected patients. We also analyzed the age, sex distribution, joint involvement, and relation of joint movement restriction with visual analog scale (VAS). MATERIALS AND METHODS: Two hundred patients clinically suspected with DENG and CHIK were enrolled from a Tertiary Care Hospital in Mumbai from April 2012 to October 2013...
July 2016: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/27249897/seroepidemiology-of-dengue-virus-infection-in-hiv-infected-children-in-comparison-to-healthy-children
#13
Usa Thisyakorn, Kanyalak Srettakraikul, Marisa Hemungkorn, Chule Thisyakorn
BACKGROUND: Dengue infection is the most common arboviral infection in the world while the HIV/AIDS epidemic remains a global concern. The pathogenesis of both diseases is rather on the contrary and it is generally observed that dengue diseases are uncommon in children with AIDS. OBJECTIVE: To study the seroprevalence of dengue virus infection in HIV-infected children compared to healthy children. MATERIAL AND METHOD: A cross-sectional seroprevalence of dengue virus was conducted at King Chulalongkorn Memorial Hospital, Bangkok, Thailand...
February 2016: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/27227883/projected-impact-of-dengue-vaccination-in-yucat%C3%A3-n-mexico
#14
Thomas J Hladish, Carl A B Pearson, Dennis L Chao, Diana Patricia Rojas, Gabriel L Recchia, Héctor Gómez-Dantés, M Elizabeth Halloran, Juliet R C Pulliam, Ira M Longini
Dengue vaccines will soon provide a new tool for reducing dengue disease, but the effectiveness of widespread vaccination campaigns has not yet been determined. We developed an agent-based dengue model representing movement of and transmission dynamics among people and mosquitoes in Yucatán, Mexico, and simulated various vaccine scenarios to evaluate effectiveness under those conditions. This model includes detailed spatial representation of the Yucatán population, including the location and movement of 1...
May 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27182269/seroprevalence-of-acute-dengue-in-a-malaysian-tertiary-medical-centre
#15
Chuan Hun Ding, Zetti Zainol Rashid, Md Mostafizur Rahman, NanFeng Khang, Wan Ngor Low, Nurabrar Hussin, Melissa Iqlima Marzuki, Alyaa Nadhira Jaafar, Nurul Ain' Nabilla Roslan, Terukumar Chandrasekaran
OBJECTIVES: The aims of this study were to determine the seroprevalence of acute dengue in Universiti Kebangsaan Malaysia (UKM) Medical Centre and its correlation with selected haematological and biochemical parameters. METHODS: This cross-sectional study was conducted from January to June 2015. A patient was serologically diagnosed with acute dengue if the dengue virus IgG, IgM or NS-1 antigen was reactive. RESULTS: Out of 1,774 patients suspected to have acute dengue, 1,153 were serologically diagnosed with the infection, resulting in a seroprevalence of 64...
March 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27055020/estimating-the-public-health-importance-of-the-cyd-tetravalent-dengue-vaccine-vaccine-preventable-disease-incidence-and-numbers-needed-to-vaccinate
#16
Bradford D Gessner, Annelies Wilder-Smith
BACKGROUND: To evaluate the potential public health impact of the live attenuated tetravalent Sanofi Pasteur dengue vaccine (CYD-TDV) we analyzed data from the reported clinical trials to calculate vaccine preventable disease incidence (VPDI) and number needed to vaccinate (NNV) based on the licensure indication for persons age 9 years and above. METHODS: VPDI is defined as incidence in an unvaccinated population X vaccine efficacy (VE), and thus incorporates both VE and the underlying burden of disease...
April 29, 2016: Vaccine
https://www.readbyqxmd.com/read/27019361/seroprevalence-of-asymptomatic-dengue-infection-in-children-in-lahore
#17
S N Mohsin, F Ghafoor, M Saleem, R Ghous, M Aasim
Dengue has become a global problem in past few decades, with half of the world's population at risk of infection. For some countries of Asia and Latin America, severe dengue is a major cause of serious illness and even death in children. Pakistan has been reported as a hyperendemic area for dengue infection. Our study aimed to find seroprevalence of past dengue infection in asymptomatic children of Lahore with no previous history of dengue infection. A total of 400 samples were collected from children aged 1-12 years in Lahore using random sampling...
August 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/26928497/-seroprevalence-of-dengue-infection-in-a-district-of-the-paraguayan-chaco-population-based-study
#18
Yenny Pereira, Margarita Samudio, Andrea Ojeda, Águeda Cabello
BACKGROUND: Dengue is an infection of great global importance with different clinical presentations. OBJECTIVE: To establish the seroprevalence of infection by the dengue virus in a district of the Paraguayan Chaco. MATERIAL AND METHODS: Cross-sectional study in 418 inhabitants of three villages in the district of Villa Hayes, Paraguay, using a probabilistic household sampling, a questionnaire and blood sampling. Antibodies were determined by the ELISA capture IgG anti dengue method and factors associated with seroprevalence were evaluated...
December 2015: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/26917954/seroepidemiology-of-asymptomatic-dengue-virus-infection-in-jeddah-saudi-arabia
#19
Ghazi A Jamjoom, Esam I Azhar, Moujahid A Kao, Raja M Radadi
BACKGROUND: Although virologically confirmed dengue fever has been recognized in Jeddah, Saudi Arabia, since 1994, causing yearly outbreaks, no proper seroepidemiologic studies on dengue virus have been conducted in this region. Such studies can define the extent of infection by this virus and estimate the proportion that may result in disease. The aim of this study was to measure the seroprevalence of past dengue virus infection in healthy Saudi nationals from different areas in the city of Jeddah and to investigate demographic and environmental factors that may increase exposure to infection...
2016: Virology: Research and Treatment
https://www.readbyqxmd.com/read/26869532/dengue-and-chikungunya-seroprevalence-in-gabonese-infants-prior-to-major-outbreaks-in-2007-and-2010-a-sero-epidemiological-study
#20
Julian Justin Gabor, Norbert Georg Schwarz, Meral Esen, Peter Gottfried Kremsner, Martin Peter Grobusch
BACKGROUND: Apart from outbreak reports, little is known about the endemicity of dengue and chikungunya virus in African countries. We investigated serum samples collected in Gabon before major outbreaks in 2007 and 2010 in order to identify pre-outbreak-circulation of both viruses. METHODS: Serum samples from Gabonese infants (162) were analyzed at 3, 9, 15 and 30 months of age by commercial ELISA for dengue and chikungunya IgG-antibodies. If samples were positive medical records of participants were analyzed for symptoms concordant with dengue and chikungunya infections during the time period of assumed seroconversion...
January 2016: Travel Medicine and Infectious Disease
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