keyword
https://read.qxmd.com/read/38288764/cigarette-smoking-is-an-independent-risk-factor-for-developing-vitiligo-on-the-hands
#21
JOURNAL ARTICLE
Yuki Enomoto, Yoshifumi Kanayama, Kyoko Ikumi, Mai Sakurai, Aya Yamamoto, Akimichi Morita
BACKGROUND: Vitiligo presents with varying clinical features based on the type and location. Treatment tends to be more effective on the face, neck, trunk, and mid-extremities, while the lips and distal extremities may be more resistant. Vitiligo in frequently exposed areas such as the face, arms, legs, and hands is typically associated with a lower Dermatology Life Quality Index. OBJECTIVES: We aimed to identify the characteristics and potential causes of vitiligo in challenging-to-treat regions, with particular focus on the hands...
January 2024: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38288763/photoprotective-effects-of-lithospermum-erythrorhizon-and-pueraria-lobata-extracts-on-uvb-induced-photoaging-a-study-on-skin-barrier-protection
#22
JOURNAL ARTICLE
Sungjin Lee, Sarang Oh, Qiwen Zheng, Shengdao Zheng, Myeongju Kim, Sejig Park, Wonmi Choi, Chang Shik Yin, Tae-Hoo Yi
AIM: Lithospermum erythrorhizon and Pueraria lobata exhibit promising potential as cosmetic additives for mitigating skin barrier impairment induced by photoaging. Despite their potential, the precise mechanisms underlying their protective and ameliorative effects remain elusive. This study sought to assess the reparative properties of Lithospermum erythrorhizon and Pueraria lobata extracts (LP) on UVB-irradiated human skin keratinocytes (HaCaT cells) and explore the therapeutic potential of LP as a skin barrier protection agent...
January 2024: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38157308/estimation-of-serum-and-tissue-level-of-interleukin-15-il-15-and-il-15-receptor-alpha-il-15r%C3%AE-in-mycosis-fungoides-before-and-after-phototherapy-an-interventional-cohort-study
#23
JOURNAL ARTICLE
Rania M Mogawer, Randa Youssef, Kholoud Helmy, Nourhan Emad, Olfat Shaker, Sarah Orabi
BACKGROUND: Mycosis fungoides (MF) is a chronic, highly recurrent cutaneous T-cell lymphoma, whose pathogenesis has not yet been fully elucidated. Interleukin-15 was previously highlighted as a viability factor for cutaneous T-cell lymphoma with previous studies shedding light on its role in pathogenesis of MF and its plausibility as a potential therapeutic target. OBJECTIVE: This study was conducted to evaluate serum and tissue expression of IL-15 and IL-15Rα in early cases of MF (IA, IB, IIA) at baseline and following phototherapy...
December 29, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38084061/a-focused-review-of-visible-light-therapies-for-vitiligo
#24
REVIEW
Mitchell J Winkie, Goranit Sakunchotpanit, Carlos E Salazar, Nicole S Gunasekera, Elizabeth A Buzney, Vinod E Nambudiri
BACKGROUND: Vitiligo can be challenging to treat and exhibit an unpredictable clinical course. Phototherapy in the form of visible light can achieve both repigmentation and depigmentation outcomes in vitiligo, with minimal associated adverse events. This review focuses on the mechanistic understandings and clinical outcomes of visible light-based treatments for vitiligo. METHODS: Articles were retrieved from PubMed starting from May 1965 until August 2023, yielding 496 unique articles...
December 11, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38069506/evaluation-of-the-protection-of-sunscreen-products-against-long-wavelength-ultraviolet-a1-and-visible-light-induced-biological-effects
#25
JOURNAL ARTICLE
Nneamaka Ezekwe, Aunna Pourang, Alexis B Lyons, Shanthi Narla, Amruth Atyam, Shereen Zia, Ben J Friedman, Iltefat H Hamzavi, Henry W Lim, Indermeet Kohli
BACKGROUND: Long wavelength ultraviolet-A1 in combination with visible light induces hyperpigmentation, particularly in dark-skin phototypes. This study evaluated the efficacy of four sunscreen formulations in protecting against VL + UVA1 (370-700 nm). METHODS: The test products (A-D) were applied to the back of 12 volunteers, then irradiated with 320 J/cm2 VL + UVA1 (3.5% UVA1 [370-400 nm]). Immediately after irradiation, and at Days 1, 7, and 14, erythema and pigmentation were assessed by investigator global assessment (IGA), colorimetry (Δa* and ΔITA) and diffuse reflectance spectroscopy (DRS)-measured relative dyschromia (area under the curve AUC)...
December 8, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38059681/frequency-of-skin-cancer-among-psoriasis-vitiligo-and-mycosis-fungoides-patients-treated-with-narrowband-ultraviolet-b-phototherapy
#26
JOURNAL ARTICLE
Ilit Mimouni, Julia Shulman, Awni Abu Unes, Lev Pavlovsky, Felix Pavlotsky
BACKGROUND: Narrowband ultraviolet B (NB-UVB) phototherapy is a popular and relatively contemporary treatment option. However, only a few studies to date have explored the potential risk of skin cancer following NB-UVB treatment. OBJECTIVE: This study aimed to investigate the potential long-term risk of skin cancer in patients treated with NB-UVB. METHODS: This cohort study included patients with psoriasis, vitiligo, and mycosis fungoides treated with NB-UVB at two university hospitals in Israel in 2000-2005...
January 2024: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38059515/awareness-of-sun-exposure-risks-and-photoprotection-for-preventing-pigmentary-disorders-in-asian-populations-survey-results-from-three-asian-countries-and-expert-panel-recommendations
#27
REVIEW
Chee Leok Goh, Hee Young Kang, Akimichi Morita, Chengfeng Zhang, Yan Wu, Cita Rosita Sigit Prakoeswa, Nguyen Huu Sau, Delphine Kerob, Frederic Flament, Liu Wei
BACKGROUND: In this article, we review and discuss the photoprotection behavior of Asians based on the literature, along with a subanalysis of an original online survey, and make recommendations to optimize photoprotection for Asian populations to prevent photoaging and pigmentary disorders. METHODS: An international panel of eight dermatologists from Asia (China, Korea, Japan, Singapore, Indonesia, and Vietnam) met to discuss sunscreen photoprotection for Asian patients...
December 7, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38018017/photobiomodulation-for-melasma-treatment-integrative-review-and-state-of-the-art
#28
REVIEW
Thais Rodrigues Galache, Michelle Mota Sena, João Alberto Fioravante Tassinary, Christiane Pavani
PURPOSE: Photobiomodulation therapy (PBM) is a versatile technique for treating skin diseases. Melasma, a chronic hyperpigmentation condition, has recently been associated with vascular features and dermal photoaging and poses significant management challenges. We review the recent literature on melasma etiology and the evidence supporting PBM as a therapeutic modality for melasma treatment. METHODS: We conducted a comprehensive literature search in three different databases from May to August 2023, focusing on studies published in the past 10 years...
November 28, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38017654/photoprotective-measures-among-adolescents-stratified-by-region-an-analysis-utilizing-the-national-college-health-assessment
#29
JOURNAL ARTICLE
Sarah J Shareef, Shanelle Jackson, Brittany N Lane, Ellanya Kallabat, Deepika Boopathy, Joseph W Fakhoury, Henry W Lim
BACKGROUND/PURPOSE: Exposure to sunlight has been shown to cause pigmentary alterations, photoaging and photocarcinogenesis. Understanding photoprotective patterns in adolescent populations is beneficial to public health initiatives. We utilized data provided by the American College Health Association's National College Health Assessment to evaluate photoprotective behaviors among adolescent populations. METHODS: Behavioral questions related to photoprotection were analyzed from the American College Health Association (ACHA) National College Health Assessment (NCHA) (Version III)...
November 28, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38009842/collagen-study-advances-for-photoaging-skin
#30
REVIEW
Helei Liu, Junjuan Dong, Rina Du, Yaoxing Gao, Pengwei Zhao
BACKGROUND: Collagen dominates the skin's extracellular matrix (ECM). Type I collagen comprises 80%-90% of the skin's collagen, followed by type III (8%-12%) and type V (5%). Reactive oxygen species, matrix metalloproteinases, and collagen degradation all increase during photoaging, which disrupts the ECM's dynamic balance and lowers the amount of total collagen in the body. In recent years, domestic and foreign researchers have conducted multidimensional and multifaceted studies on collagen and skin photoaging...
November 27, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37984828/narrowband-ultraviolet-b-phototherapy-combined-with-intralesional-injection-of-either-latanoprost-or-platelet-rich-plasma-for-stable-nonsegmental-vitiligo
#31
RANDOMIZED CONTROLLED TRIAL
Manal Fawzy, Sahar Al-Mokadem, Mabrokah Alshereef, Basma Elkholy
BACKGROUND: Narrowband ultraviolet B (NB-UVB) phototherapy is the cornerstone of vitiligo treatment. Its combination with other treatments usually yields a better response. Latanoprost, a prostaglandin F2α analog, and autologous platelet-rich plasma (PRP) have been reported to be effective for vitiligo. AIM: To evaluate the efficacy of NB-UVB combined with intralesional latanoprost or PRP for stable nonsegmental vitiligo (NSV). METHODS: Sixty patients with stable NSV were recruited and randomly allocated to two equal groups...
January 2024: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37984448/multiple-recurrent-cutaneous-squamous-cell-carcinomas-in%C3%A2-situ-secondary-to-epidermodysplasia-verruciformis-a-case-report-and-successful-treatment-with-aminolevulinic-acid-photodynamic-therapy
#32
JOURNAL ARTICLE
Shiwen Wang, Yige Zhao, Chenyu Tang, Panpan Wang, Yangyang Ma, Mengyan Zhu, Jiaqi Wang, Ping Wang
No abstract text is available yet for this article.
November 20, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37968826/optimizing-the-administrated-light-dose-during-5-ala-mediated-photodynamic-therapy-murine-4t1-breast-cancer-model
#33
JOURNAL ARTICLE
Hossein Amiri, Manijhe Mokhtari-Dizaji, Hossein Mozdarani
Photodynamic therapy (PDT) is already used to treat many cancers, including breast cancer, the most common cancer in women worldwide. The destruction basis of this method is on produced singlet oxygen which is extremely reactive and is a major agent of tumor cell killing. The measurement of singlet oxygen produced within PDT is essential in predicting treatment outcomes and their optimization. This study aims to determine the optimal total light dose administered during PDT by calculating the singlet oxygen to facilitate the prediction of the treatment outcome in mice bearing 4T1 cell breast cancer...
January 2024: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37961814/fermented-black-ginseng-extract-prevents-uvb-induced-inflammation-by-regulating-the-nc886-pkr-pathway-in-human-keratinocytes
#34
JOURNAL ARTICLE
Yuna Kim, Junbo Sim, Kyungeun Jeon, Dehun Ryu, Youngeun Ji, Youngseok Kim, Junoh Kim, Suwon Jeon, Deokhoon Park, Eunsun Jung
BACKGROUND: Continuous exposure of the skin to ultraviolet B (UVB) rays can cause inflammation and photodamage. In previous studies, we observed that the upregulation of nc886, a noncoding RNA (ncRNA), can alleviate UVB-induced inflammation through suppression of the protein kinase RNA (PKR) pathway. We aim to investigate the effect of fermented black ginseng extract (FBGE), which has been shown to increase the expression of nc886, on UVB-induced inflammation in keratinocytes. METHODS: To confirm the cytotoxicity of FBGE, MTT assay was performed, and no significant cytotoxicity was found on human keratinocytes...
November 14, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37957888/treatment-with-a-red-laser-based-wound-therapy-device-exerts-positive-effects-in-models-of-delayed-keratinocyte-and-fibroblast-wound-healing
#35
JOURNAL ARTICLE
Cornelia Wiegand, Annegret Dirksen, Jörg Tittelbach
BACKGROUND: Light therapy is widely used in medicine. Specifically, photobiomodulation has been shown to exert beneficial effects in wound healing disorders, which present a major challenge in health care. The study's aim was providing information on the effect of a novel, red-laser-based wound therapy device (WTD) on keratinocytes and fibroblasts during wound healing under optimal and non-optimal conditions. METHODS: The scratch wound assay was employed as a wound healing model for mechanical damage with readjustment of specific cell milieus, explicitly chronic TH1 inflammation and TH2-dominant conditions...
November 13, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37927110/evaluation-of-social-knowledge-on-photoprotection-and-its-relationship-with-education-and-age-in-a-polish-seaside-town-during-summer-holidays
#36
JOURNAL ARTICLE
Julia Woźna, Jan Stępka, Andrzej Bałoniak, Zygmunt Adamski
OBJECTIVE: This survey aimed to evaluate knowledge of photoprotection among individuals from a random group in a resort town in Poland, Kołobrzeg, and explore the correlation between their knowledge and demographics like age, gender, education, and residence. METHODS: An anonymous survey was conducted among a diverse group. This population comprised individuals from various backgrounds: health spa patients undergoing treatments, therapies and medical appointments, guests visiting the resort for leisure, passersby, and staff working at the spa and recreational facilities...
November 5, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37898983/the-efficacy-and-safety-of-low-versus-high-fluence-fractional-picosecond-nd-yag-1064-nm-laser-in-the-treatment-of-acne-scars-a-randomized-split-face-comparison-study
#37
JOURNAL ARTICLE
Si-Hyung Lee, Dong Hyo Kim, Seong Jin Jo, Youngkyoung Lim, Ji Won Lee, Jun Hyo Lee, Tae Min Kim, Seong Rae Kim, Jeewoo Kang, Ji Young Yoon, Dae Hun Suh
BACKGROUND: Differences in clinical efficacy based on the fluence of fractional picosecond laser treatment for acne scars are unknown. OBJECTIVE: To compare the efficacy and safety of low-fluence versus high-fluence fractional picosecond Nd:YAG 1064-nm laser treatment in acne scar patients. METHODS: In this 12-week, investigator-blinded, randomized, split-face study, 25 patients with moderate-to-severe acne scars received three sessions of high-fluence laser treatment (1...
October 29, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37890996/the-effects-of-long-pulsed-alexandrite-laser-therapy-on-facial-redness-and-skin-microbiota-compositions-in-rosacea-a-prospective-multicentre-single-arm-clinical-trial
#38
JOURNAL ARTICLE
Sujin Park, Hyunwoo Jang, Seol Hwa Seong, Ji Young Kim, Eun Jung Lee, Yu Jeong Bae, Yong Ju Ahn, Jihee Kim, Sang Ho Oh
BACKGROUND: Rosacea is a chronic skin disorder characterised by abnormal neurovasculature and inflammation in the central region of the face. The efficacy of pulsed-dye laser and intense pulsed light treatments for rosacea have been demonstrated in several clinical trials. However, there is currently no research on the efficacy of long-pulsed alexandrite laser (LPAL) therapy alone for rosacea-related facial redness and its effect on skin microbiota. AIM: To evaluate the efficacy of LPAL therapy on facial redness in rosacea and assess changes in skin microbiota composition...
October 27, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37882104/luminescence-of-favipiravir-in-skin-appendages-and-sclera-a%C3%A2-controlled-study-and-literature-review
#39
JOURNAL ARTICLE
Deniz Demircioğlu, Emel Öztürk Durmaz
BACKGROUND/OBJECTIVES: Favipiravir is an antiviral agent, recently used for COVID-19 infections. Several reports associate favipiravir intake with Wood's lamp fluorescence of hair, nails, and sclera. The present study was designed to elucidate the positivity rates, and sites of favipiravir-related fluorescence and to unravel the site-specific changes in fluorescence positivity rates by a function of time past exposure. METHODS: The study population comprised 50 patients and 50 control individuals...
October 26, 2023: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/37859524/efficacy-of-using-oral-methotrexate-with-phototherapy-in-the-treatment-of-vitiligo-in-comparison-with-single-phototherapy-treatment-a-double-blinded-randomized-controlled-trial
#40
JOURNAL ARTICLE
Vahide Lajevardi, Zahra Sadat Seyed Hosseini, Sama Heidari
BACKGROUND: Vitiligo is an acquired skin disease with a worldwide prevalence of 0.5%-2% and a tendency to involve both genders. Although the exact pathologic mechanism is unknown, there is some evidence for the role of autoimmunity in this disease. Based on this theory, various immunosuppressive agents, such as topical or systemic corticosteroids and phototherapy (including narrowband ultraviolet B), are used. Methotrexate is another immunosuppressant that has recently become popular as a single treatment for vitiligo; however, the synergistic effect and its superiority over other treatments are two crucial factors that are still obscure...
October 20, 2023: Photodermatology, Photoimmunology & Photomedicine
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