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https://www.readbyqxmd.com/read/28079770/neurodevelopmental-outcomes-after-assisted-reproductive-technologies
#1
Jacques Balayla, Odile Sheehy, William D Fraser, Jean R Séguin, Jacquetta Trasler, Patricia Monnier, Andrea A MacLeod, Marie-Noëlle Simard, Gina Muckle, Anick Bérard
OBJECTIVE: To compare children's cognitive, motor, and language development at 2 years of age after assisted reproductive technologies (ARTs) relative to natural conception. METHODS: The 3D-Study (2010-2012) is a prospective cohort study, which sought to improve the understanding among perinatal events, obstetric outcomes, and child development. A total of 2,366 pregnant women were recruited, of whom 278 conceived with ART: ovarian stimulation, intrauterine sperm insemination, in vitro fertilization, intracytoplasmic sperm injection, or in vitro maturation...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28071974/from-ancient-greece-to-the-cognitive-revolution-a-comprehensive-view-of-physical-rehabilitation-sciences
#2
David Martínez-Pernía, Óscar González-Castán, David Huepe
The development of rehabilitation has traditionally focused on measurements of motor disorders and measurements of the improvements produced during the therapeutic process; however, physical rehabilitation sciences have not focused on understanding the philosophical and scientific principles in clinical intervention and how they are interrelated. The main aim of this paper is to explain the foundation stones of the disciplines of physical therapy, occupational therapy, and speech/language therapy in recovery from motor disorder...
January 10, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28069561/cancer-survivors-experience-with-telehealth-a-systematic-review-and-thematic-synthesis
#3
REVIEW
Anna Cox, Grace Lucas, Afrodita Marcu, Marianne Piano, Wendy Grosvenor, Freda Mold, Roma Maguire, Emma Ream
BACKGROUND: Net survival rates of cancer are increasing worldwide, placing a strain on health service provision. There is a drive to transfer the care of cancer survivors-individuals living with and beyond cancer-to the community and encourage them to play an active role in their own care. Telehealth, the use of technology in remote exchange of data and communication between patients and health care professionals (HCPs), is an important contributor to this evolving model of care. Telehealth interventions are "complex," and understanding patient experiences of them is important in evaluating their impact...
January 9, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28057878/pseudoautosomal-abnormalities-in-terminal-azfb-c-deletions-are-associated-with-isochromosomes-yp-and-may-lead-to-abnormal-growth-and-neuropsychiatric-function
#4
A Castro, F Rodríguez, M Flórez, P López, B Curotto, D Martínez, A Maturana, M C Lardone, C Palma, V Mericq, M Ebensperger, F Cassorla
STUDY QUESTION: Are copy number variations (CNVs) in the pseudoautosomal regions (PARs) frequent in subjects with Y-chromosome microdeletions and can they lead to abnormal stature and/or neuropsychiatric disorders? SUMMARY ANSWER: Only subjects diagnosed with azoospermia factor (AZF)b+c deletions spanning to the end of the Y chromosome (i.e. terminal deletions) harbor Y isochromosomes and/or cells 45,X that lead to pseudoautosomal gene CNVs, which were associated with abnormal stature and/or neuropsychiatric disorders...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28056017/when-hearing-is-tricky-speech-processing-strategies-in-prelingually-deafened-children-and-adolescents-with-cochlear-implants-having-good-and-poor-speech-performance
#5
Magdalene Ortmann, Pienie Zwitserlood, Arne Knief, Johanna Baare, Stephanie Brinkheetker, Antoinette Am Zehnhoff-Dinnesen, Christian Dobel
Cochlear implants provide individuals who are deaf with access to speech. Although substantial advancements have been made by novel technologies, there still is high variability in language development during childhood, depending on adaptation and neural plasticity. These factors have often been investigated in the auditory domain, with the mismatch negativity as an index for sensory and phonological processing. Several studies have demonstrated that the MMN is an electrophysiological correlate for hearing improvement with cochlear implants...
2017: PloS One
https://www.readbyqxmd.com/read/28035492/factors-influencing-the-use-of-a-mobile-app-for-reporting-adverse-drug-reactions-and-receiving-safety-information-a-qualitative-study
#6
Sieta T de Vries, Lisa Wong, Alastair Sutcliffe, François Houÿez, Carmen Lasheras Ruiz, Peter G M Mol
INTRODUCTION: A mobile app may increase the reporting of adverse drug reactions (ADRs) and improve the communication of new drug safety information. Factors that influence the use of an app for such two-way risk communication need to be considered at the development stage. OBJECTIVE: Our aim was to reveal the factors that may influence healthcare professionals (HCPs) and patients to use an app for two-way risk communication. METHODS: Focus group discussions and face-to-face interviews were conducted in the Netherlands, Spain and the UK...
December 29, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28034410/a-review-of-electronic-medical-record-keeping-on-mobile-medical-service-trips-in-austere-settings
#7
REVIEW
Christopher Dainton, Charlene H Chu
INTRODUCTION: Electronic medical records (EMRs) may address the need for decision and language support for Western clinicians on mobile medical service trips (MSTs) in low resource settings abroad, while providing improved access to records and data management. However, there has yet to be a review of this emerging technology used by MSTs in low-resource settings. The aim of this study is to describe EMR systems designed specifically for use by mobile MSTs in remote settings, and accordingly, determine new opportunities for this technology to improve quality of healthcare provided by MSTs...
February 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28027678/participatory-design-methods-in-telemedicine-research
#8
Jane Clemensen, Mette J Rothmann, Anthony C Smith, Liam J Caffery, Dorthe B Danbjorg
Healthcare systems require a paradigm shift in the way healthcare services are delivered to counteract demographic changes in patient populations, expanding technological developments and the increasing complexity of healthcare. Participatory design (PD) is a methodology that promotes the participation of users in the design process of potential telehealth applications. A PD project can be divided into four phases including: the identification and analysis of participant needs; the generation of ideas and development of prototypes; testing and further development of prototypes; and evaluation...
January 1, 2016: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28025919/amcp-partnership-forum-enabling-the-exchange-of-clinical-and-economic-information-pre-fda-approval
#9
(no author information available yet)
: Current federal laws and FDA regulations have significantly restricted the sharing of clinical and health economic information on biopharmaceuticals that have yet to receive FDA approval. Over the past several years, organizations that make health care coverage decisions, including those that set copayments, premiums, and formulary placement, have expressed a need for receiving this information before approval, as long as appropriate safeguards exist to prevent this information from reaching unintended entities...
January 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28004089/divisible-atoms-or-none-at-all-facing-the-european-contributions-to-developments-of-chemistry-and-physics-in-china
#10
Stanislav Južnič
One of the most important Mid-European professor with more than six thousand academic descendants was the leading Slovenian erudite Jurij Vega. In broader sense, Vega's and other applied sciences of the south of Holy Roman Empire of German Nationality were connected with the mercury mine of Idrija during the last half of millennia. The Idrija Mine used to be one of the two top European producers of mercury, the basic substance of atomistic alchemists. Idrija Mine contributions to the history of techniques, their examinations and approbations is comparable to the other Mid-European achievements...
December 2016: Acta Chimica Slovenica
https://www.readbyqxmd.com/read/27997930/vhdl-descriptions-for-the-fpga-implementation-of-pwl-function-based-multi-scroll-chaotic-oscillators
#11
Esteban Tlelo-Cuautle, Antonio de Jesus Quintas-Valles, Luis Gerardo de la Fraga, Jose de Jesus Rangel-Magdaleno
Nowadays, chaos generators are an attractive field for research and the challenge is their realization for the development of engineering applications. From more than three decades ago, chaotic oscillators have been designed using discrete electronic devices, very few with integrated circuit technology, and in this work we propose the use of field-programmable gate arrays (FPGAs) for fast prototyping. FPGA-based applications require that one be expert on programming with very-high-speed integrated circuits hardware description language (VHDL)...
2016: PloS One
https://www.readbyqxmd.com/read/27993779/recon2neo4j-applying-graph-database-technologies-for-managing-comprehensive-genome-scale-networks
#12
Irina Balaur, Alexander Mazein, Mansoor Saqi, Artem Lysenko, Christopher J Rawlings, Charles Auffray
: The goal of this work is to offer a computational framework for exploring data from the Recon2 human metabolic reconstruction model. Advanced user access features have been developed using the Neo4j graph database technology and this paper describes key features such as efficient management of the network data, examples of the network querying for addressing particular tasks, and how query results are converted back to the Systems Biology Markup Language (SBML) standard format. The Neo4j-based metabolic framework facilitates exploration of highly connected and comprehensive human metabolic data and identification of metabolic subnetworks of interest...
December 19, 2016: Bioinformatics
https://www.readbyqxmd.com/read/27992262/the-kit-motion-language-dataset
#13
Matthias Plappert, Christian Mandery, Tamim Asfour
Linking human motion and natural language is of great interest for the generation of semantic representations of human activities as well as for the generation of robot activities based on natural language input. However, although there have been years of research in this area, no standardized and openly available data set exists to support the development and evaluation of such systems. We, therefore, propose the Karlsruhe Institute of Technology (KIT) Motion-Language Dataset, which is large, open, and extensible...
December 2016: Big Data
https://www.readbyqxmd.com/read/27991974/an-observatory-to-gather-and-disseminate-information-on-the-health-related-effects-of-environmental-and-climate-change
#14
Christovam Barcellos, Emmanuel Roux, Pietro Ceccato, Pierre Gosselin, Antonio Miguel Monteiro, Vanderlei Pascoal de Matos, Diego Ricardo Xavier
This report sought to critically examine proposals, potentials, and challenges of environmental health observatories with an emphasis on climate change processes. A critical review of existing environmental health observatories was performed, examining their purposes, potential audiences, and technological platforms. The implementation of the Brazilian Climate and Health Observatory (C&HO) is described, and two stages are defined: (i) the requirement analysis and negotiation stage that identified the national and regional institutional players and their roles as data producers/users; and (ii) thematic health-related workshops that reviewed water-related diseases, vector-borne diseases, extreme climate events, and health problems derived from forest fires...
September 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/27982714/technology-assisted-language-intervention-for-children-who-are-deaf-or-hard-of-hearing-a-pilot-study-of-augmentative-and-alternative-communication-for-enhancing-language-development
#15
Jareen Meinzen-Derr, Susan Wiley, Rose McAuley, Laura Smith, Sandra Grether
PURPOSE: Pilot study to assess the effect of augmentative and alternative communication technology to enhance language development in children who are deaf or hard-of-hearing. MATERIALS AND METHODS: Five children ages 5-10 years with permanent bilateral hearing loss who were identified with language underperformance participated in an individualized 24-week structured program using the application TouchChat WordPower on iPads(®). Language samples were analyzed for changes in mean length of utterance, vocabulary words and mean turn length...
December 16, 2016: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/27977903/elementary-my-dear-watson-the-era-of-natural-language-processing-in-transplantation
#16
EDITORIAL
Bing Ho, Anton Skaro, Samantha Montag, Lihui Zhao
The use of modern data acquisition and analytics commonly in use in the technology sector by Google, IBM, and others have long been the envy of the health services researcher. In this issue, Srinivas et al. have demonstrated feasibility in the use of data mining and natural language processing (NLP) in data abstraction.(1) In their study they developed predictive models for graft loss and patient survival in kidney transplantation using single-center retrospective data. This article is protected by copyright...
December 15, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27976457/global-health-and-emergency-care-overcoming-clinical-research-barriers
#17
Adam C Levine, Meagan A Barry, Pooja Agrawal, Herbert C Duber, Mary P Chang, Joy M Mackey, Bhakti Hansoti
OBJECTIVES: There are many barriers impeding the conduct of high-quality emergency care research, particularly in low- and middle-income countries. Several of these barriers were originally outlined in 2013 as part of the Academic Emergency Medicine Global Health and Emergency Care Consensus Conference. This paper seeks to establish a broader consensus on the barriers to emergency care research globally and proposes a comprehensive array of new recommendations to overcome these barriers...
December 15, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/27968903/efficacy-and-safety-of-prostate-targeted-local-therapy-in-patients-with-newly-diagnosed-oligometastatic-prostate-cancer-a-systematic-review-and-meta-analysis
#18
Shi Qiu, Lu Yang, Linghui Deng, Liangren Liu, Ping Han, Qiang Wei
BACKGROUND: The role of local therapy for the management of oligometastatic prostate cancer at diagnosis still remains poorly defined. We did a systematic review and meta-analysis evaluating local therapy of the primary tumour for patients with oligometastatic prostate cancer at diagnosis as well as the patients who can benefit the most. METHODS: For this systematic review, we searched PubMed, EMBASE, Medline, and the Cochrane Library for studies from database inception until March, 2016, for local therapy of the primary tumour in patients with oligometastatic prostate cancer...
October 2016: Lancet
https://www.readbyqxmd.com/read/27965858/development-and-feasibility-of-a-swallowing-intervention-package-sip-for-patients-receiving-radiotherapy-treatment-for-head-and-neck-cancer-the-sip-study-protocol
#19
Mary Wells, Emma King, Kate Toft, Fiona MacAulay, Joanne Patterson, Nadine Dougall, Nick Hulbert-Williams, Sally Boa, Eleanor Slaven, Julie Cowie, John McGarva, Patricia Gail Niblock, Julie Philp, Justin Roe
BACKGROUND: Head and neck cancer (HNC) is the sixth most common cancer worldwide, and the functional, psychological and social consequences of HNC cancer and its treatment can be severe and chronic. Dysphagia (swallowing problems) affects up to two thirds of patients undergoing combined chemoradiotherapy. Recent reviews suggest that prophylactic swallowing exercises may improve a range of short- and long-term outcomes; however, the importance of psychological and behavioural factors on adherence to swallowing exercises has not been adequately studied...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27915497/current-and-future-development-of-extended-release-abuse-deterrent-opioid-formulations-in-the-united-states
#20
Lynn R Webster, John Markman, Edward J Cone, Gwendolyn Niebler
Prescription opioid misuse and abuse in the United States (US) is epidemic and is a major burden on health-care resources and costs to society. The need to significantly reduce the risks of prescription opioid misuse and abuse must be balanced with the important needs of patients with chronic pain who may benefit from treatment with opioids. The use of abuse-deterrent formulations (ADFs) of prescription opioids is one approach that could reduce the risk of prescription opioid abuse and misuse while maintaining access to opioids...
December 12, 2016: Postgraduate Medicine
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