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https://www.readbyqxmd.com/read/29667705/intellectual-disability-in-cerebral-palsy-a-population-based-retrospective-study
#1
Susan M Reid, Elaine M Meehan, Sarah J Arnup, Dinah S Reddihough
AIM: A population-based observational study design was used to describe the epidemiology of intellectual disability in cerebral palsy (CP) in terms of clinical and neuroimaging associations, and to report the impact of intellectual disability on utilization of health services and length of survival. METHOD: Population CP registry data were used to retrospectively assess the frequency of intellectual disability and strength of associations between intellectual disability and mobility, epilepsy, vision, hearing, communication, and neuroimaging patterns (n=1141)...
April 18, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29666163/neurodevelopmental-impairment-among-extremely-preterm-infants-in-the-neonatal-research-network
#2
Ira Adams-Chapman, Roy J Heyne, Sara B DeMauro, Andrea F Duncan, Susan R Hintz, Athina Pappas, Betty R Vohr, Scott A McDonald, Abhik Das, Jamie E Newman, Rosemary D Higgins
OBJECTIVES: Evaluate the spectrum of neurodevelopmental outcome in a contemporary cohort of extremely preterm infants. We hypothesize that the rate of severe neurodevelopmental impairment (NDI) decreases over time. METHODS: Retrospective analysis of neurodevelopmental outcome of preterm infants ≤27 weeks' gestational age (GA) from a Neonatal Research Network center that completed neurodevelopmental follow-up assessments between April 1, 2011, and January 1, 2015...
April 17, 2018: Pediatrics
https://www.readbyqxmd.com/read/29656928/benign-paroxysmal-migraine-variants-of-infancy-and-childhood-transitions-and-clinical-features
#3
Jacob Brodsky, Karampreet Kaur, Talia Shoshany, Sophie Lipson, Guangwei Zhou
INTRODUCTION: Migraine variant disorders of childhood include benign paroxysmal torticollis of infancy (BPTI) and benign paroxysmal vertigo of childhood (BPVC). This study aimed to review our experience with BPTI and BPVC and determine the incidence of children transitioning between each of these disorders and to vestibular migraine (VM). METHODS: We retrospectively reviewed the medical records of patients seen at the Balance and Vestibular Program at Boston Children's Hospital between January 2012 and December 2016 who were diagnosed with BPTI, BPVC, and/or VM...
March 30, 2018: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29655975/vestibular-and-balance-function-is-often-impaired-in-children-with-profound-unilateral-sensorineural-hearing-loss
#4
Meirav Sokolov, Karen A Gordon, Melissa Polonenko, Susan I Blaser, Blake C Papsin, Sharon L Cushing
RATIONALE: Children with unilateral deafness could have concurrent vestibular dysfunction which would be associated with balance deficits and potentially impair overall development. The prevalence of vestibular and balance deficits remains to be defined in these children. METHODS: Twenty children with unilateral deafness underwent comprehensive vestibular and balance evaluation. RESULTS: Retrospective review revealed that more than half of the cohort demonstrated some abnormality of the vestibular end organs (otoliths and horizontal canal), with the prevalence of end organ specific dysfunction ranging from 17 to 48% depending on organ tested and method used...
April 3, 2018: Hearing Research
https://www.readbyqxmd.com/read/29615062/kars-related-diseases-progressive-leukoencephalopathy-with-brainstem-and-spinal-cord-calcifications-as-new-phenotype-and-a-review-of-literature
#5
Anna Ardissone, Davide Tonduti, Andrea Legati, Eleonora Lamantea, Rita Barone, Imen Dorboz, Odile Boespflug-Tanguy, Gabriella Nebbia, Marco Maggioni, Barbara Garavaglia, Isabella Moroni, Laura Farina, Anna Pichiecchio, Simona Orcesi, Luisa Chiapparini, Daniele Ghezzi
BACKGROUND: KARS encodes lysyl- transfer ribonucleic acid (tRNA) synthetase, which catalyzes the aminoacylation of tRNA-Lys in the cytoplasm and mitochondria. Eleven families/sporadic patients and 16 different mutations in KARS have been reported to date. The associated clinical phenotype is heterogeneous ranging from early onset encephalopathy to isolated peripheral neuropathy or nonsyndromic hearing impairment. Recently additional presentations including leukoencephalopathy as predominant cerebral involvement or cardiomyopathy, isolated or associated with muscular and cerebral involvement, have been reported...
April 4, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29605391/valganciclovir-is-beneficial-in-children-with-congenital-cytomegalovirus-and-isolated-hearing-loss
#6
Yehonatan Pasternak, Liron Ziv, Joseph Attias, Jacob Amir, Efraim Bilavsky
OBJECTIVE: To evaluate the efficacy of antiviral treatment for infants with congenital cytomegalovirus (cCMV) with isolated sensorineural hearing loss (SNHL). STUDY DESIGN: Data were reviewed retrospectively for infants with isolated SNHL who received prolonged antiviral treatment between 2005 and 2017. Hearing status was evaluated for infants who had been followed for >1 year. RESULTS: Among 329 infants treated for cCMV, 59 (18%) were born with isolated SNHL...
March 28, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29605369/frequency-specific-auditory-brainstem-response-testing-with-age-appropriate-sedation
#7
Yael Levit, Dror Mandel, Idit Matot
OBJECTIVE: Auditory brainstem response (ABR) testing is the gold-standard procedure for hearing evaluation in pediatric patients who cannot complete a behavioral hearing test. The amount of audiological information obtained depends on the quality of the patient's sleep during the test. In this retrospective database review, we aimed to assess the amount and the characteristics of the audiological information obtained in ABR testing in pediatric patients with age-appropriate sedation. METHODS: A retrospective chart review was conducted on 501 consecutive ABR sedation sessions performed between January 2014 and June 2016 at the Tel Aviv Medical Center...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29605368/differences-and-similarities-in-early-vocabulary-development-between-children-with-hearing-aids-and-children-with-cochlear-implant-enrolled-in-3-year-auditory-verbal-intervention
#8
Lone Percy-Smith, Maria Hallstrøm, Jane Lignel Josvassen, Jeanette Hølledig Mikkelsen, Lena Nissen, Eveline Dieleman, Per Cayé-Thomasen
OBJECTIVE: The overall objective of this study was to evaluate the implementation of a Nordic Auditory Verbal (AV) intervention for children with all degrees and types of hearing impairment (HI) using all kinds of hearing technology. A first specific objective was to identify differences and similarities in early vocabulary development between children with cochlear implant (CI) compared with children with hearing aids (HAs)/Bone anchored hearing aids (Bahs) enrolled in a 3-year AVprogram, and to compare the group of children with HI to a control group of children with normal hearing (NH)...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29605349/utility-of-whole-exome-sequencing-in-the-diagnosis-of-usher-syndrome-report-of-novel-compound-heterozygous-myo7a-mutations
#9
Khushnooda Ramzan, Mohammed Al-Owain, Rozeena Huma, Selwa A F Al-Hazzaa, Sarah Al-Ageel, Faiqa Imtiaz, Moeenaldeen Al-Sayed
Next generation sequencing (NGS), such as targeted panel sequencing, whole-exome sequencing and whole-genome sequencing has led to an exponential increase of elucidated genetic causes in both rare diseases, and common but heterogeneous disorders. NGS is applied in both research and clinical settings, and the clinical exome sequencing (CES), which provides not only the sequence variation data but also clinical interpretation, aids in reaching a final conclusion with regards to a genetic diagnosis. Usher syndrome is a group of disorders, characterized by bilateral sensorineural hearing loss, with or without vestibular dysfunction and retinitis pigmentosa...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29605341/high-level-heteroplasmy-for-the-m-7445a-g-mitochondrial-dna-mutation-can-cause-progressive-sensorineural-hearing-loss-in-infancy
#10
Kana Matsushima, Atsuko Nakano, Yukiko Arimoto, Hideki Mutai, Kazuki Yamazawa, Kei Murayama, Tatsuo Matsunaga
OBJECTIVE: Hearing loss caused by mutation of mitochondrial DNA typically develops in late childhood or early adulthood, but rarely in infancy. We report the investigation of a patient to determine the cause of his early onset hearing loss. MATERIALS AND METHODS: The proband was a boy aged 1 year and 2 months at presentation. Newborn hearing screening test by automated auditory brainstem response generated "pass" results for both ears. His reaction to sound deteriorated by 9 months...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29605336/development-and-standardization-of-arabic-words-in-noise-test-in-egyptian-children
#11
Tayseer Taha Abdel Rahman
OBJECTIVES: To develop and establish norms of Arabic Words in Noise test in Egyptian children. METHOD: Total number of participants was 152 with normal hearing and ranging in age from 5 to 12 years. They are subdivided into two main groups (standardization group) which comprised 120 children with normal scholastic achievement and (application group) which comprised 32 children with different types of central auditory processing disorders. Arabic version of both Speech perception in noise (SPIN) and Words in Noise (WIN) tests were presented in each ear at zero signal to-noise ratio (SNR) using ipsilateral Cafeteria noise fixed at 50 dB sensation level (dBSL)...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29602859/prevalence-of-childhood-hearing-impairment-of-different-severities-in-urban-and-rural-areas-a-nationwide-population-based-study-in-taiwan
#12
Cheng-Yu Lin, Yen-Cheng Tseng, How-Ran Guo, Der-Chung Lai
OBJECTIVE: Childhood hearing impairment (CHI) is a major developmental disability, but data at the national level are limited, especially those on different severities. We conducted a study to fill this data gap. DESIGN: A nationwide study on the basis of a reporting system. SETTING: To provide services to disabled citizens, the Taiwanese government maintains a registry of certified cases. Using data from this registry, we estimated prevalence rates of CHI of different severities from 2004 to 2010 and made comparisons between urban and rural areas...
March 30, 2018: BMJ Open
https://www.readbyqxmd.com/read/29594073/enhancing-working-memory-capacity-in-persian-cochlear-implanted-children-a-clinical-trial-study
#13
Afsaneh Doosti, Maryam Jalalipour, Tayebeh Ahmadi, Seyed Basir Hashemi, Shapour Haghjou, Enayatollah Bakhshi
Introduction: Sensory deprivations such as hearing impairment that affect sensory input have a secondary impact on cognitive functions such as working memory (WM). WM capacity is an important cognitive component that processes language-related activities. Moreover, several studies have shown a deficit in WM in children with a cochlear implant (CI). We aimed to assess the performance of children with CIs in pre- and post-training sessions and compare their scores on a battery of WM tests to investigate the efficacy of a WM training program...
March 2018: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29587304/vocal-emotion-identification-by-children-using-cochlear-implants-relations-to-voice-quality-and-musical-interests
#14
Teija Waaramaa, Tarja Kukkonen, Sari Mykkänen, Ahmed Geneid
Purpose: Listening tests for emotion identification were conducted with 8-17-year-old children with hearing impairment (HI; N = 25) using cochlear implants, and their 12-year-old peers with normal hearing (N = 18). The study examined the impact of musical interests and acoustics of the stimuli on correct emotion identification. Method: The children completed a questionnaire with their background information and noting musical interests. They then listened to vocal stimuli produced by actors (N = 5) and consisting of nonsense sentences and prolonged vowels ([a:], [i:], and [u:]; N = 32) expressing excitement, anger, contentment, and fear...
March 27, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29573766/-quality-of-life-of-children-with-otitis-media-and-impact-of-insertion-of-transtympanic-ventilation-tubes-in-a-portuguese-population
#15
Ana Rita Lameiras, Deodato Silva, Assunção O Neill, Pedro Escada
INTRODUCTION: Quality of life is an important measure for health-outcome evaluation. Although otitis media is one of the most common childhood diseases, its impact on Portuguese children's quality of life is unknown. The aim of this study is to determine the quality of life of Portuguese children with chronic otitis media with effusion and/or recurrent acute otitis media and the short-term impact of transtympanic ventilation tubes, using the Portuguese version of the OM-6 questionnaire, a valid, reliable and sensitive instrument to evaluate the health-related quality of life in children with otitis media...
January 31, 2018: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/29557793/school-age-hearing-screening-based-on-speech-in-noise-perception-using-the-digit-triplet-test
#16
Sam Denys, Michael Hofmann, Heleen Luts, Cécile Guérin, Ann Keymeulen, Katelijne Van Hoeck, Astrid van Wieringen, Karel Hoppenbrouwers, Jan Wouters
OBJECTIVES: This study aims to investigate the large-scale applicability of the Digit Triplet test (DTT) for school-age hearing screening in fifth grade elementary (5E) (9 to 12 years old) and third grade secondary (3S) (13 to 16 years old) school children. The reliability of the test is investigated as well as whether pass/fail criteria need to be corrected for training and/or age, and whether these criteria have to be refined with respect to referral rates and pure-tone audiometry results...
March 19, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29549688/identification-of-risk-factors-for-hearing-impairment-in-newborns-a-hospital-based-study
#17
Nermin Hrnčić
Aim To identify risk factors for hearing impairment presented in neonates born in Cantonal Hospital Zenica (CHZ) and to estimate their influence on outcome of hearing tests in Newborn Hearing Screening (NHS). Methods Retrospective-prospective study was done at the Department of Gynaecology and Maternity. The NHS was performed with transitory evoked otoacoustic emissions (TEOAE) during a six-month period using "Titan" device (Interacoustics, Denmark). The questionnaire was written for the purpose of getting more structured basic information about every newborn and to identify risk factors for hearing impairment...
February 1, 2018: Medicinski Glasnik
https://www.readbyqxmd.com/read/29549372/long-term-neurodevelopmental-outcomes-of-premature-infants-in-singapore
#18
Charmaine M Teo, Woei Bing Poon, Selina Ky Ho
INTRODUCTION: Neonatal care advances have resulted in improved survival but have raised concerns of increase in neurodevelopmental impairment. This study looked at long-term neurodevelopmental outcomes at ages 5 and 8 years of very low birthweight infants born in the 2000s as compared to the 1990s. Neurodevelopmental assessment at 2 years old was compared to that at 5 and 8 years to determine if assessment at 2 years was predictive of later outcomes. MATERIALS AND METHODS: A retrospective cohort study of consecutive infants with birthweight less than 1250 grams admitted to a tertiary centre in Singapore between January 1994 to December 1995 (Epoch I) and January 2004 to December 2005 (Epoch II) were included...
February 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29540880/enabling-profound-hearing-impaired-children-to-articulate-words-using-lip-reading-through-software-application
#19
Lozina Shoaib, Sharifullah Khan, Muhammad Azeem Abbas, Ahmad Salman
OBJECTIVE: To mitigate the communication barriers of profound hearing-impaired children by enabling their word articulation ability. METHODS: This pre-experimental pilot study was conducted from September 2016 to March 2017 at the National Special Education Centre for Hearing Impaired Children, Islamabad, Pakistan, and comprised deaf children of both genders aged 5-8 years. A specially designed software application for lip-reading was employed to help the subjects articulate words...
March 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29528912/congenital-cmv-and-hiv-perinatal-transmission
#20
Kristina Adachi, Jiahong Xu, Bonnie Ank, D Heather Watts, Margaret Camarca, Lynne M Mofenson, Jose Henrique Pilotto, Esau Joao, Glenda Gray, Gerhard Theron, Breno Santos, Rosana Fonseca, Regis Kreitchmann, Jorge Pinto, Marisa M Mussi-Pinhata, Daisy Maria Machado, Mariana Ceriotto, Mariza G Morgado, Yvonne J Bryson, Valdilea G Veloso, Beatriz Grinsztejn, Mark Mirochnick, Jack Moye, Karin Nielsen-Saines
BACKGROUND: Congenital cytomegalovirus (CMV) infection (cCMV) is an important cause of hearing loss and cognitive impairment. Prior studies suggest that HIV-exposed children are at higher risk of acquiring cCMV. We assessed the presence, magnitude, and risk factors associated with cCMV among infants born to HIV-infected women, who were not receiving antiretrovirals during pregnancy. METHODS: cCMV and urinary CMV load were determined in a cohort of infants born to HIV-infected women not receiving antiretrovirals during pregnancy...
March 9, 2018: Pediatric Infectious Disease Journal
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