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https://www.readbyqxmd.com/read/29441834/speech-processing-to-improve-the-perception-of-speech-in-background-noise-for-children-with-auditory-processing-disorder-and-typically-developing-peers
#1
Sheila Flanagan, Tudor-Cătălin Zorilă, Yannis Stylianou, Brian C J Moore
Auditory processing disorder (APD) may be diagnosed when a child has listening difficulties but has normal audiometric thresholds. For adults with normal hearing and with mild-to-moderate hearing impairment, an algorithm called spectral shaping with dynamic range compression (SSDRC) has been shown to increase the intelligibility of speech when background noise is added after the processing. Here, we assessed the effect of such processing using 8 children with APD and 10 age-matched control children. The loudness of the processed and unprocessed sentences was matched using a loudness model...
January 2018: Trends in Hearing
https://www.readbyqxmd.com/read/29404299/long-term-follow-up-of-retinoblastoma-survivors-experience-from-india
#2
Rachna Seth, Amitabh Singh, Vijay Guru, Bhavna Chawla, Sushmita Pathy, Savita Sapra
Background: Retinoblastoma (Rb) is the most common primary intraocular tumor of infancy and childhood. Survivors' ocular and visual problems and increased risk for subsequent malignancy are well documented, but data on long-term health status of Rb survivors are limited, this being particularly true for India. Methodology: Children who had completed treatment for Rb at least 2 years ago before and were under follow-up at the after cancer treatment clinic were evaluated...
October 2017: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29398506/international-consensus-icon-on-management-of-otitis-media-with-effusion-in-children
#3
F Simon, M Haggard, R M Rosenfeld, H Jia, S Peer, M-N Calmels, V Couloigner, N Teissier
Otitis media with effusion (OME) is a common childhood disease defined as the presence of liquid in the middle ear without signs or symptoms of acute ear infection. Children can be impacted mainly with hearing impairment and/or co-occurring recurrent acute otitis media (AOM) thus requiring treatment. Although many meta-analyses and national guidelines have been issued, management remains difficult to standardize, and use of surgical and medical treatments continue to vary. We convened an international consensus conference as part of the 2017 International Federation of Oto-rhino-laryngological Societies Congress, to identify best practices in OME management...
February 2, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29395617/unilateral-congenital-hearing-loss-in-children-challenges-and-potentials
#4
REVIEW
Astrid van Wieringen, An Boudewyns, Anouk Sangen, Jan Wouters, Christian Desloovere
The estimated incidence of sensorineural hearing impairment (>40 dB HL) at birth is 1.86 per 1000 newborns in developed countries and 30-40% of these are unilateral. Profound sensorineural unilateral hearing impairment or single sided deafness (SSD) can be treated with a cochlear implant. However, this treatment is costly and invasive and unnecessary in the eyes of many. Very young children with SSD often do not exhibit language and cognitive delays and it is hard to imagine that neurocognitive skills will present difficulties with one good ear...
January 30, 2018: Hearing Research
https://www.readbyqxmd.com/read/29395407/can-live-music-therapy-reduce-distress-and-pain-in-children-with-burns-after-wound-care-procedures-a-randomized-controlled-trial
#5
Marianne J E van der Heijden, Johannes Jeekel, Heinz Rode, Sharon Cox, Joost van Rosmalen, Myriam G M Hunink, Monique van Dijk
OBJECTIVE: Burn wound care procedures are very painful and lead to distress. Live music therapy has shown beneficial effects on distress and pain in specific pediatric patient populations. In this study we measured whether live music therapy has beneficial effects in terms of less distress and pain in children with burns after wound care procedures. METHODS: This randomized assessor-blinded controlled trial (RCT) took place at the burns unit of the Red Cross War Memorial Children's Hospital, Cape Town, South Africa...
January 30, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29382611/novel-variant-in-sp7-osx-associated-with-recessive-osteogenesis-imperfecta-with-bone-fragility-and-hearing-impairment
#6
Melissa Fiscaletti, Andrew Biggin, Bruce Bennetts, Karen Wong, Julie Briody, Verity Pacey, Catherine Birman, Craig F Munns
Osteogenesis imperfecta (OI) is a connective tissue disorder characterized by low bone density and recurrent fractures with a wide genotypic and phenotypic spectrum. Common features include short stature, opalescent teeth, blue sclerae and hearing impairment. The majority (>90%) of patients with OI have autosomal dominant variants in COL1A1/COL1A2, which lead to defects in type 1 collagen. More recently, numerous recessive variants involving other genes have also been identified. Sp7/Osx gene, is a protein coding gene that encodes a zinc finger transcription factor, osterix, which is a member of the Sp subfamily of sequence-specific DNA-binding proteins...
January 27, 2018: Bone
https://www.readbyqxmd.com/read/29378570/improving-early-audiological-intervention-via-newborn-hearing-screening-in-belgium
#7
Bénédicte Vos, Christelle Senterre, Michel Boutsen, Raphaël Lagasse, Alain Levêque
BACKGROUND: Newborn hearing screening programs aim to lower the ages at audiological intervention among hearing-impaired children. In Wallonia and Brussels (Belgium), audiological intervention data are not collected in the screening program, and the ages at initiating audiological care have never been assessed. This study aimed to assess the evolution in the ages at initiating audiological intervention in the context of a newborn hearing screening program implementation. METHODS: This population-based descriptive study used data from the Belgian healthcare billing database...
January 30, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29371904/computer-based-auditory-training-programs-for-children-with-hearing-impairment-a-scoping-review
#8
REVIEW
Manohar Nanjundaswamy, Prashanth Prabhu, Revathi Kittur Rajanna, Raghavendra Gulaganji Ningegowda, Madhuri Sharma
Introduction  Communication breakdown, a consequence of hearing impairment (HI), is being fought by fitting amplification devices and providing auditory training since the inception of audiology. The advances in both audiology and rehabilitation programs have led to the advent of computer-based auditory training programs (CBATPs). Objective  To review the existing literature documenting the evidence-based CBATPs for children with HIs. Since there was only one such article, we also chose to review the commercially available CBATPs for children with HI...
January 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29359854/clinical-features-btd-gene-mutations-and-their-functional-studies-of-eight-symptomatic-patients-with-biotinidase-deficiency-from-southern-china
#9
Zongcai Liu, Xiaoyuan Zhao, Huiying Sheng, Yanna Cai, Xi Yin, Xiaodan Chen, Ling Su, Zhikun Lu, Chunhua Zeng, Xiuzhen Li, Li Liu
Biotinidase (BTD) deficiency is a rare autosomal recessive metabolic disease, which develops neurological and cutaneous symptoms because of the impaired biotin recycling. Pathogenic mutations on BTD gene cause BTD deficiency. Clinical features and mutation analysis of Chinese children with BTD deficiency were rarely described. Herein, for the first time, we reported the clinical features, BTD gene mutations and their functional studies of eight symptomatic children with BTD deficiency from southern China. Fatigue, hypotonia, proximal muscular weakness, hearing deficits, rash and respiratory problems are common clinical phenotype of our patients...
January 23, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29354163/secondary-aneurysmal-bone-cyst-in-mccune-albright-syndrome
#10
Symeon Tournis, Alexia Balanika, Panayiotis D Megaloikonomos, Andreas F Mavrogenis
Polyostotic fibrous dysplasia in combination with caféau-lait macules and hyperfunctioning endocrinopathies consists of a rare clinical condition termed as McCune-Albright syndrome. Aneurysmal bone cysts are tumor-like cystic lesions, composed of blood-filled compartments. They may occur as primary lesions or secondary to other pathologies; most commonly giant cell tumors of bone. However, secondary aneurysmal bone cysts in McCune-Albright syndrome are exceptional. We present a 28-year-old female with McCune-Albright syndrome...
September 2017: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/29341395/health-of-southern-tasmanian-4-to-6-year-old-children-in-out-of-home-care-compared-to-peers
#11
Marie Rauter, Anagha Jayakar, Tom Clemens, Zaharenia Galanos, Louise Newbery, Andrew Whelan
AIM: To compare the health of 4- to 6-year-old children in out-of-home care (OOHC) in Southern Tasmania with their peers. METHODS: Demographic and health data collection and prospective health assessment of all 4- to 6-year olds in OOHC in Southern Tasmania on 30 August 2011 was undertaken. Data were compared to Tasmanian and/or Australian peers. RESULTS: A total of 109 of 129 children aged 4 to 6 years were included in the study. Time in OOHC was on average 38 (range 0-76) months...
January 17, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29330554/accuracy-of-a-screening-tool-for-early-identification-of-language-impairment
#12
Noëlle Uilenburg, Karin Wiefferink, Paul Verkerk, Margot van Denderen, Carla van Schie, Anne-Marie Oudesluys-Murphy
Purpose: A screening tool called the VTO Language Screening Instrument (VTO-LSI) was developed to enable more uniform and earlier detection of language impairment. This report, consisting of 2 retrospective studies, focuses on the effects of using the VTO-LSI compared to regular detection procedures. Method: Study 1 retrospectively compared VTO-LSI with regular detection procedures. Outcome measure was the detection rate of language impairment among 24-month-old children...
January 12, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29326878/ten-year-long-enzyme-replacement-therapy-shows-a-poor-effect-in-alleviating-giant-leg-ulcers-in-a-male-with-fabry-disease
#13
Jun Okada, Mohammad Arif Hossain, Chen Wu, Takashi Miyajima, Hiroko Yanagisawa, Keiko Akiyama, Yoshikatsu Eto
Fabry disease is an X-linked lysosomal storage disorder caused by a deficiency of α-galactosidase A (α-gal A), leading to the progressive accumulation of glycosphingolipids. Classical hemizygous males usually present symptoms, including pain and paresthesia in the extremities, angiokeratoma, hypo- or anhidrosis, abdominal pain, cornea verticillata, early stroke, tinnitus, and/or hearing loss, during early childhood or adolescence. Moreover, proteinuria, renal impairment, and cardiac hypertrophy can appear with age...
March 2018: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/29314150/role-of-intelligence-quotient-iq-on-anxiety-and-behavior-in-children-with-hearing-and-speech-impairment
#14
Raghavendra M Shetty, Aditi Pashine, Nijo A Jose, Somasundar Mantha
AIM: To assess and compare the role of IQ on anxiety and behavior of children with and without hearing and speech impairment. MATERIAL AND METHODS: A total of 120 children of age group 7-14 years were included in the study, of which control group comprised of 60 normal healthy children and 60 hearing and speech impaired children formed the study group. The study was done in two consecutive sessions. First appointment for Culture Fair Intelligence Test and second appointment for RMS pictorial anxiety score (RMS-PS) and Frankl behavior rating which were assessed during oral prophylaxis...
January 4, 2018: Special Care in Dentistry
https://www.readbyqxmd.com/read/29305691/the-capos-mutation-in-atp1a3-alters-na-k-atpase-function-and-results-in-auditory-neuropathy-which-has-implications-for-management
#15
Lisbeth Tranebjærg, Nicola Strenzke, Sture Lindholm, Nanna D Rendtorff, Hanne Poulsen, Himanshu Khandelia, Wojciech Kopec, Troels J Brünnich Lyngbye, Christian Hamel, Cecile Delettre, Beatrice Bocquet, Michael Bille, Hanne H Owen, Toke Bek, Hanne Jensen, Karen Østergaard, Claes Möller, Linda Luxon, Lucinda Carr, Louise Wilson, Kaukab Rajput, Tony Sirimanna, Katherine Harrop-Griffiths, Shamima Rahman, Barbara Vona, Julia Doll, Thomas Haaf, Oliver Bartsch, Hendrik Rosewich, Tobias Moser, Maria Bitner-Glindzicz
Cerebellar ataxia, areflexia, pes cavus, optic atrophy and sensorineural hearing impairment (CAPOS) is a rare clinically distinct syndrome caused by a single dominant missense mutation, c.2452G>A, p.Glu818Lys, in ATP1A3, encoding the neuron-specific alpha subunit of the Na+/K+-ATPase α3. Allelic mutations cause the neurological diseases rapid dystonia Parkinsonism and alternating hemiplegia of childhood, disorders which do not encompass hearing or visual impairment. We present detailed clinical phenotypic information in 18 genetically confirmed patients from 11 families (10 previously unreported) from Denmark, Sweden, UK and Germany indicating a specific type of hearing impairment-auditory neuropathy (AN)...
January 5, 2018: Human Genetics
https://www.readbyqxmd.com/read/29289454/audiometric-assessment-of-pediatric-patients-with-cystic-fibrosis
#16
Kathryn L Kreicher, Michael J Bauschard, Clarice S Clemmens, Concetta Maria Riva, Ted A Meyer
BACKGROUND: The purpose of this study was to evaluate hearing impairment in pediatric patients with cystic fibrosis (CF). METHODS: This is a retrospective analysis of the AudGen database generated by Children's Hospital of Philadelphia. Audiograms were analyzed for type of hearing loss (HL), pure-tone-average (PTA), laterality, and change in hearing over time. Medical charts were reviewed to identify factors that influence development and progression of hearing loss...
December 27, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/29287859/hearing-loss-in-children-with-primary-ciliary-dyskinesia
#17
Kathryn L Kreicher, Heather K Schopper, Akash N Naik, Jonathan L Hatch, Ted A Meyer
OBJECTIVES: To evaluate the type and severity of hearing impairment in pediatric patients with primary ciliary dyskinesia (PCD) and relate these measures to patient demographics, treatment options, and other otologic factors. METHODS: A retrospective analysis of children with a diagnosis of PCD, Kartagener's syndrome, or situs inversus in the AudGen Database was conducted. Audiograms were analyzed for type of hearing loss (HL), severity, laterality, and progression...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29286928/long-term-neurodevelopment-outcome-of-caffeine-versus-aminophylline-therapy-for-apnea-of-prematurity
#18
S Khurana, M Shivakumar, G V Sujith Kumar Reddy, P Jayashree, Y Ramesh Bhat, L E S Lewis
OBJECTIVE: Methylxanthines are the most commonly prescribed drug in neonatal setups. However, Clinicians show indecision in choosing the right agent for Apnea of Prematurity in most of the developing countries. Present study aimed to compare rate of mortality and survival with normal neurodevelopment outcome at 18 to 24 months of corrected age, between Caffeine- and Aminophylline-treated infants for apnea of prematurity. METHODS: 240 infants were randomly allocated to caffeine and aminophylline for apnea of prematurity during February 2012 to January 2015...
2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29285148/correlation-between-cd64-and-pct-levels-in-cerebrospinal-fluid-and-degree-of-hearing-impairment-sequelae-in-neonates-with-purulent-meningitis
#19
Cui Liu, Dongchi Zhao
This study investigated the possible correlation between the degree of hearing impairment caused by neonatal purulent meningitis and the levels of CD64 and PCT in cerebrospinal fluid of patients, and assessed the prognostic value of such levels. We recorded data from 156 cases of neonatal purulent meningitis retrospectively. All the patients received brainstem response audiometry, and cerebrospinal fluid samples were collected within the first day after admission through lumbar puncture. Flow cytometry was used to detect CD64 levels and enzyme-linked fluorescent assay was used to detect PCT levels...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29278615/risk-for-speech-and-language-impairments-in-pre-school-aged-hiv-exposed-uninfected-children-with-in-utero-combination-antiretroviral-exposure
#20
Mabel L Rice, Jonathan S Russell, Toni Frederick, Murli Purswani, Paige L Williams, George K Siberry, Sean M Redmond, Howard J Hoffman, Tzy-Jyun Yao
BACKGROUND: Perinatally HIV-exposed but uninfected (HEU) children have elevated risk of late language emergence at age 1 year, with possible links to in utero antiretroviral (ARV) exposure. We investigated possible risks for speech impairments (SI) and language impairments (LI) in preschool monolingual HEU children in the United States. METHODS: Speech and language assessments were conducted as part of the PHACS Surveillance Monitoring of ART Toxicities (SMARTT) study at ages 3 (N= 208) and 5 (N = 429) years...
December 22, 2017: Pediatric Infectious Disease Journal
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