keyword
https://read.qxmd.com/read/38496696/imaging-performance-of-thoracic-smarca4-deficient-undifferentiated-tumor-a-case-report-and-literature-review
#21
Di Yang, Yong Wang
BACKGROUND: SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) is a class of high-grade malignant tumors that has only been described in recent years, with an undifferentiated or rhabdoid morphology and genetic deletion of SMARCA4 ( BRG1 ), a subunit of the BRG1 -associated factors (BAFs) chromatin remodeling complex. It is a rare tumor type that occurs in young to middle-aged men and usually presents as a compressive thoracic mass with rapid progression and poor prognosis. However, much remains unknown about the clinical and imaging manifestations of the disease...
February 29, 2024: Translational Lung Cancer Research
https://read.qxmd.com/read/38496391/attitudes-toward-covid-19-vaccines-during-pregnancy-and-breastfeeding
#22
JOURNAL ARTICLE
Nesibe Simsekoglu, Enes Akyuz, Rabia Guven, Ozge Pasin
BACKGROUND: Although vaccination is one of the most effective means of controlling the spread of COVID-19, public concerns and indecision about vaccination still continue. Because pregnant and breastfeeding individuals are at high risk for severe outcomes in case of infections, determining their level of hesitation and attitude toward COVID-19 vaccines will guide the management of the disease. This study aimed to determine pregnant and breastfeeding women's levels of hesitation and attitude toward COVID-19 vaccines as well as their related factors...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38496372/systematic-review-and-critical-appraisal-of-prediction-models-for-readmission-in-coronary-artery-disease-patients-assessing-current-efficacy-and-future-directions
#23
REVIEW
Yunhao Zhang, Xuejiao Zhu, Fuer Gao, Shulan Yang
PURPOSE: Coronary artery disease (CAD) patients frequently face readmissions due to suboptimal disease management. Prediction models are pivotal for detecting early unplanned readmissions. This review offers a unified assessment, aiming to lay the groundwork for enhancing prediction models and informing prevention strategies. METHODS: A search through five databases (PubMed, Web of Science, EBSCOhost, Embase, China National Knowledge Infrastructure) up to September 2023 identified studies on prediction models for coronary artery disease patient readmissions for this review...
2024: Risk Management and Healthcare Policy
https://read.qxmd.com/read/38496371/effects-of-the-first-wave-of-the-covid-19-pandemic-on-the-work-readiness-of-undergraduate-nursing-students-in-china-a-mixed-methods-study
#24
JOURNAL ARTICLE
Lifang He, Jean Rizza A Dela Cruz
BACKGROUND: Newly graduated nurses with strong work readiness are more likely to smoothly transition from school to clinical settings. However, even before the pandemic, this transition from nursing graduate to clinical nurse was often challenging. Therefore, this study aims to investigate the impact of the initial wave of COVID-19 on the work readiness of nursing students. METHODS: A convergent mixed-method design was employed. For the quantitative study, an online cross-sectional survey was conducted among 500 graduating nursing students from four Chinese public higher education institutions...
2024: Risk Management and Healthcare Policy
https://read.qxmd.com/read/38496370/catastrophic-health-expenditure-and-associated-factors-among-hospitalized-cancer-patients-in-addis-ababa-ethiopia
#25
JOURNAL ARTICLE
Girum Yihun Matebie, Anagaw Derseh Mebratie, Tamiru Demeke, Bezawit Afework, Eva J Kantelhardt, Adamu Addissie
BACKGROUND: Out-of-pocket (OOP) health expenditures for cancer care expose households to unanticipated economic consequences. When the available health services are mainly dependent on OOP expenditure, the household faces catastrophic health expenditure (CHE). This study aimed to estimate the incidence and intensity of CHE in hospitalized cancer patients and identify coping strategies and associated factors. METHOD AND MATERIAL: Hospital-based cross-sectional study design was conducted on 305 cancer inpatients in Addis Ababa between November 2021 and February 2022...
2024: Risk Management and Healthcare Policy
https://read.qxmd.com/read/38496170/hypoparathyroidism-revealed-by-unsuccessful-anti-epileptic-therapy
#26
Raja Arrab, Youssef Benchehab, Fadila Guessous, Nezha Dini
Pediatric hypoparathyroidism is an uncommon endocrine disease that can be either isolated or syndromic. It occurs when the secretion of parathormone is insufficient to maintain normal levels of ionized calcium. Patients with hypoparathyroidism can exhibit cerebral calcifications and metabolic disorders, and the severity of such features is inversely correlated with hypocalcemia. We report a case of a 13-year-old patient who was initially diagnosed with epilepsy by another medical team two years before her admission to our hospital and who was subjected to oral valproate therapy...
February 2024: Curēus
https://read.qxmd.com/read/38496145/outcomes-of-percutaneous-image-guided-and-laparoscopic-cholecystostomies-in-high-risk-patients-with-acute-calculus-cholecystitis-a-five-year-district-general-hospital-experience
#27
JOURNAL ARTICLE
Mahmoud S Aly, Zohaib Jamal, Zeeshan Khawaja, Phuong L Kieu, Nowera Zafar, Divya Kanakalingam, Ahmed Khalil
Introduction Acute cholecystitis (AC), inflammation of the gall bladder, is one of the most common emergency surgical presentations. In the UK, approximately 15% of the population is estimated to have gallstones, and approximately 20% of them can develop AC. Laparoscopic cholecystectomy (LC) is considered the definitive management of AC. However, cholecystectomy carries a very high risk of morbidity and mortality in high-risk frail patients with multiple comorbidities who are deemed unfit for surgery. Percutaneous cholecystostomy (PC), both image-guided and laparoscopic, is generally acknowledged as an interim treatment measure before definitive management, which is the LC...
February 2024: Curēus
https://read.qxmd.com/read/38496112/munchausen-syndrome-in-the-context-of-liaison-psychiatry-a-case-report-and-a-narrative-review
#28
Odete Nombora, Eva Mendes, André Oliveira, Lúcia Ribeiro
Munchausen Syndrome (MS) has been widely recognized as a severe manifestation of factitious disorder, a condition where individuals intentionally fabricate or exaggerate symptoms for psychological gratification. It represents a complex diagnostic challenge due to its elusive nature and intricate relationship with various medical conditions. We present a clinical case of a 44-year-old woman observed in the context of Liaison Psychiatry, demonstrating the intricate interplay between chronic medical conditions, psychiatric factors, and the challenges in diagnosing and managing MS...
February 2024: Curēus
https://read.qxmd.com/read/38496098/country-of-origin-of-medical-products-and-risk-of-labour-rights-abuse-a-cross-sectional-analysis-using-four-procurement-datasets
#29
JOURNAL ARTICLE
Jasmin Abbott, Chantelle Rizan, James N Smith, Merete Loeken, Mei L Trueba, Mahmood F Bhutta
Background Case studies have highlighted labour rights abuse in the manufacture of several healthcare products, but little is known about the scale of the problem or the specific products involved. We aimed to quantify and compare the overall and product-specific risks of labour rights abuse in the manufacture of healthcare products supplied to high-income settings using multiple datasets on the product country of origin (COO). Methods Public procurement data from South-Eastern Norway (n=23,972 products) were compared to datasets from three other high-income settings: procurement data from Cambridge University Hospitals, trade data from UN Comtrade, and registry data from the US Food and Drug Administration (FDA)...
February 2024: Curēus
https://read.qxmd.com/read/38496085/osteopathic-manipulative-treatment-during-post-operative-recovery-a-scoping-review
#30
REVIEW
Chandler G Randall, Heather A Paul, Heather Lumley, Angelica Ortega, Jace Rowley, Bailey Brown, Sukanya Mohan, Kristina Smith, Thomas Messer, Emily Swan, Rohit S Mehra
Surgery is a common and often necessary treatment option for a wide range of medical conditions, with an estimated 40 to 50 million surgeries performed in the US alone each year. While the various types of surgeries performed may be effective in treating or managing different conditions, the post-operative period can be challenging for patients. Osteopathic manipulative treatment (OMT) is a hands-on approach to medical care that seeks to restore balance and harmony to the body from the lens of an interconnected mind, body, and spirit...
February 2024: Curēus
https://read.qxmd.com/read/38496079/dysphagia-secondary-to-myotonic-dystrophy-unveiled-in-a-case-of-destructive-spondylitis-with-synovitis-acne-pustulosis-hyperostosis-osteitis-sapho-syndrome-presenting-as-torticollis
#31
Yoshinori Ishikawa, Takashi Kobayashi, Ryo Shoji, Naohisa Miyakoshi
To report an instructive case involving destructive spondylitis and synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome, presenting with torticollis and postoperative dysphagia without hoarseness, attributed to hidden myotonic dystrophy (DM). A 51-year-old male patient with a cervical deformity, who was previously managed conservatively for a metastatic tumor, underwent reconstruction surgery and subsequently experienced postoperative dysphagia. The presence of destructive spondylitis with torticollis, warranting prompt assessment to prevent paralysis, adds complexity to the delayed identification of DM...
February 2024: Curēus
https://read.qxmd.com/read/38496076/the-impact-of-an-undergraduate-community-based-medical-education-program-in-a-japanese-urban-city
#32
JOURNAL ARTICLE
Satoshi Hiramine, Masaharu Nagata, Mosaburo Kainuma
INTRODUCTION:  With an aging global population posing healthcare challenges, especially in community healthcare, training professionals for community healthcare remains a global educational challenge, including in Japan. While previous research shows increased student interest in community healthcare through practical experiences, the focus has primarily been on rural areas, leaving a gap in understanding urban-based community medical education. This study aimed to evaluate the impact of urban community-based medical education on students' understanding and attitudes toward community healthcare...
February 2024: Curēus
https://read.qxmd.com/read/38496063/an-atypical-case-of-polycystic-ovarian-syndrome-and-possible-newly-diagnosed-systemic-lupus-erythematosus-complicated-with-a-cerebrovascular-accident-in-a-young-female-a-case-report
#33
Divine Besong Arrey Agbor, Derek Ugwendum, Barath Prashanth Sivasubramanian, Maureen A Ojwaka, Sabastain F Forsah, Shakirat Gold-Olufadi, Tochukwu Nzeako, Rita Offor, Nkafu Bechem Ndemazie, Jay Nfonoyim
Polycystic ovary syndrome (PCOS) is the leading cause of endocrine disorders among females of reproductive age and is linked with autoimmune disorders. PCOS has been associated with autoantibodies such as antinuclear antibody (ANA), anti-thyroid, and anti-Smith (anti-SM). Young patients with PCOS and systemic lupus erythematosus (SLE) have up to a 10-fold increase in stroke. We present a case of a patient with a history of PCOS (on metformin), hypothyroidism, and pulmonary embolism who presented to the emergency room with acute left-sided weakness...
February 2024: Curēus
https://read.qxmd.com/read/38496028/six-sigma-evaluation-of-17-biochemistry-parameters-using-bias-calculated-from-internal-quality-control-and-external-quality-assurance-data
#34
JOURNAL ARTICLE
Tülay Çevlik, Goncagül Haklar
BACKGROUND: Six Sigma is a popular quality management system that enables continuous monitoring and improvement of analytical performance in the clinical laboratory. We aimed to calculate sigma metrics and quality goal index (QGI) for 17 biochemical analytes and compare the use of bias from internal quality control (IQC) and external quality assurance (EQA) data in the calculation of sigma metrics. METHODS: This retrospective study was conducted in Marmara University Pendik E&R Hospital Biochemistry Laboratory...
January 25, 2024: Journal of Medical Biochemistry
https://read.qxmd.com/read/38496005/quality-of-life-and-glucose-regulation-in-pediatric-patients-with-type-1-diabetes-a-study-in-the-ningxia-hui-autonomous-region
#35
JOURNAL ARTICLE
Hua Bai, Na He, Yan Zhang, Aqsa Ahmad, Xing-Xing Yang, Yan Ma, Li-Jun Liang
OBJECTIVE: In this study, we aimed to evaluate the current status of the quality of life (QOL) of pediatric patients and plasma glucose concentration regulation in children with type 1 diabetes (T1DM) in the Ningxia Hui autonomous region. METHODS: The study involved children with T1DM admitted to the General Hospital of Ningxia Medical University between October 2011 and October 2021. The children and their parents completed general information and quality of life (QOL) questionnaires...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38496004/risk-prediction-of-diabetes-progression-using-big-data-mining-with-multifarious-physical-examination-indicators
#36
JOURNAL ARTICLE
Xiaohong Chen, Shiqi Zhou, Lin Yang, Qianqian Zhong, Hongguang Liu, Yongjian Zhang, Hanyi Yu, Yongjiang Cai
PURPOSE: The purpose of this study is to explore the independent-influencing factors from normal people to prediabetes and from prediabetes to diabetes and use different prediction models to build diabetes prediction models. METHODS: The original data in this retrospective study are collected from the participants who took physical examinations in the Health Management Center of Peking University Shenzhen Hospital. Regression analysis is individually applied between the populations of normal and prediabetes, as well as the populations of prediabetes and diabetes, for feature selection...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38495972/the-role-of-probiotics-in-the-eradication-of-helicobacter-pylori-and-overall-impact-on-management-of-peptic-ulcer-a-study-involving-patients-undergoing-triple-therapy-in-bangladesh
#37
JOURNAL ARTICLE
Taslima Zaman, Ahsanul Haq, Rahnuma Ahmad, Susmita Sinha, Kona Chowdhury, Sultana Parvin, Mostofa Imran, Zaman U Humayra, Santosh Kumar, Mainul Haque
Background Helicobacter pylori infection has been identified to cause constantly recurring inflammation, leading to gastrointestinal tract disorders, including carcinoma. The standard triple therapy (STT), used to eradicate H. pylori, includes two antimicrobials and a proton pump inhibitor for two weeks. Other drug regimens have also been developed since H. pylori exhibits antimicrobial resistance. These regimens, including probiotics, have been shown to lower adverse drug reactions (ADR), improve drug adherence, exert bacteriostatic effect, and reduce inflammation...
March 2024: Curēus
https://read.qxmd.com/read/38495965/internal-hernia-through-a-mesenteric-defect-following-esophagectomy-and-reconstruction-with-a-stomach-preserved-ileocolic-interposition
#38
Daisuke Tomita, Kentoku Fujisawa, Yu Ohkura, Masaki Ueno, Harushi Udagawa
Esophagectomy is the standard treatment for esophageal cancer and often involves the stomach as a substitute organ for esophageal reconstruction. However, we actively perform stomach-preserved ileocolic interposition because of its advantages in gastrointestinal function and the prevention of reflux esophagitis. Despite its benefits, few facilities perform esophageal reconstruction with ileocolic interposition; hence, postoperative complications following this procedure have rarely been reported. We present the first case of internal hernia through a mesenteric defect following esophagectomy and reconstruction with a stomach-preserved ileocolic interposition...
March 2024: Curēus
https://read.qxmd.com/read/38495860/application-of-standardized-management-and-effect-evaluation-of-chronic-obstructive-pulmonary-disease-patients-using-the-big-data-center-of-the-internet-of-things
#39
JOURNAL ARTICLE
Xiaoping Chen, Fei He, Yan Jiang, Xuezhen Chen, Yubing Yan
OBJECTIVE: Early detection, diagnosis, treatment and management of chronic obstructive pulmonary disease can lower morbidity and perhaps mortality. This study aimed to evaluate the effect of the application of standardized management against the background of the rapid development of the big data center of modern internet of things technology. METHODS: Participants ≥40 years of age with chronic obstructive pulmonary disease presenting at Xiamen Medical College Affiliated Haicang Hospital from October 2019 to October 2020 were selected as the observation patients based on the Internet of Things big data center for chronic obstructive pulmonary disease standardized management, and control patients from the community were selected for without down to the chronic obstructive pulmonary disease standardized management...
2024: Digital Health
https://read.qxmd.com/read/38495831/urothelial-carcinoma-masquerading-as-retroperitoneal-fibrosis-a-case-report
#40
David Luengo, Ángela Salmerón, Antonio Medina, Javier Pastor, Mercedes Caba
Retroperitoneal fibrosis, a rare and often idiopathic condition, poses significant diagnostic challenges. While most cases are considered idiopathic or immune-mediated, a small but important proportion are associated with malignant neoplasms, with implications for prognosis and management. The present study describes the case of a 69-year-old man who presented to the emergency department of the Virgen de las Nieves University Hospital (Granada, Spain), with a 2-week history of epigastric pain, vomiting and altered bowel habits...
May 2024: Oncology Letters
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