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https://www.readbyqxmd.com/read/29770363/the-multifaceted-clinical-presentation-of-vcp-proteinopathy-in-a-greek-family
#1
George K Papadimas, George P Paraskevas, Thomas Zambelis, Chrisostomos Karagiaouris, Mara Bourbouli, Anastasia Bougea, Maggie C Walter, Nicolas U Schumacher, Sabine Krause, Elisabeth Kapaki
VCP-proteinopathy is a multisystem neurodegenerative disorder caused by mutations in valosin containing protein. Here, we report the first Greek case of VCP-proteinopathy in a 62 year old patient with a slowly progressing muscular weakness since his mid-40s and a severe deterioration during the last year. He also manifested dementia with prominent neuropsychiatric symptoms, including aggression, apathy, palilalia and obsessions. Brain MRI revealed frontal atrophy, while muscle MRI showed diffuse muscle atrophy...
December 2017: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
https://www.readbyqxmd.com/read/29739236/risk-factor-assessment-in-a-greek-cohort-of-patients-with-large-abdominal-aortic-aneurysms
#2
Georgios Makrygiannis, Evanthia Mourmoura, Konstantinos Spanos, Nikolaos Roussas, Helena Kuivaniemi, Natzi Sakalihasan, Aspasia Tsezou, Athanasios Giannoukas
Environmental and genetic risk factors contribute to the etiology of abdominal aortic aneurysms (AAAs). Matrix metalloproteinases (MMPs) have been associated with the pathophysiology of AAAs. A prospective, nonrandomized case-control study was undertaken to investigate the risk factors for large AAAs (≥5.5 cm) among 175 male Greek AAA patients and to compare the results with a cohort of 166 male controls free from any aortic dilatation, as confirmed by ultrasonography from an existing AAA screening program in the same region...
January 1, 2018: Angiology
https://www.readbyqxmd.com/read/29701135/from-illusion-to-reality-a-brief-history-of-robotic-surgery
#3
Marco Vito Marino, Galyna Shabat, Gaspare Gulotta, Andrzej Lech Komorowski
PURPOSE: Robotic surgery is currently employed for many surgical procedures, yielding interesting results. METHODS: We performed an historical review of robots and robotic surgery evaluating some critical phases of its evolution, analyzing its impact on our life and the steps completed that gave the robotics its current popularity. RESULTS: The origins of robotics can be traced back to Greek mythology. Different aspects of robotics have been explored by some of the greatest inventors like Leonardo da Vinci, Pierre Jaquet-Droz, and Wolfgang Von-Kempelen...
April 1, 2018: Surgical Innovation
https://www.readbyqxmd.com/read/29685841/history-of-plastic-surgery-art-philosophy-and-rhinoplasty
#4
REVIEW
Valdas Macionis
The 200th anniversary of K. F. Graefe's "Rhinoplasty," E. Zeis' naming of the specialty of plastic surgery in 1838, and the continuing discussion on what is plastic surgery have prompted this historical-conceptual review with a semantic insight into the meaning of the word "plastic." A literature search has revealed that this term contains dual aspects: artistic and philosophical. The progressive development of these two connotations can be traced from their origin in the ceramics and the myths of ancient Greeks to their metamorphoses in fine arts, science, and philosophy of plasticity of the modern day...
March 23, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29679301/contemporary-antithrombotic-treatment-in-patients-with-non-valvular-atrial-fibrillation-undergoing-percutaneous-coronary-intervention-rationale-and-design-of-the-greek-antiplatelet-atrial-fibrillation-grape-af-registry
#5
Ioanna Xanthopoulou, Vasiliki-Maria Dragona, Periklis Davlouros, Costas Tsioufis, Efstathios Iliodromitis, Dimitrios Alexopoulos
BACKGROUND: Approximately 5 to 7% of patients undergoing percutaneous coronary intervention (PCI) for the treatment of coronary artery disease require chronic oral anticoagulation (OAC) on top of aspirin and a P2Y12 receptor antagonist, mainly due to non-valvular atrial fibrillation (AF). The advent of non-vitamin K antagonist oral anticoagulants (NOACs) increased treatment options, while there is cumulative evidence that dual combination of a NOAC and a P2Y12 receptor antagonist attenuates risk of bleeding, compared to traditional triple therapy, consisting of a vitamin K antagonist (VKA), aspirin, and a P2Y12 receptor antagonist, without significantly compromising efficacy...
April 20, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29642968/review-historical-and-futuristic-developments-in-bovine-semen-technology
#6
P Lonergan
Up to the 18th century, the prevailing view of reproduction, or 'generation' as it was referred to, was that organisms develop from miniatures of themselves, termed preformation. The alternative theory, epigenesis, proposed that the structure of an animal emerges gradually from a relatively formless egg. The teachings of the Ancient Greeks who argued either that both sexes each contributed 'semen' to form the embryo, or held a more male-centred view that the female merely provided fertile ground for the male seed to grow, dominated thinking until the 17th century, when the combined work of numerous scholars led to the theory that all female organisms, including humans, produced eggs...
April 12, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29570260/the-history-of-varicocele-from-antiquity-to-the-modern-era
#7
Antonio Marte
Men have most likely been affected by varicocele since the assumption of the upright position. In De Medicina, written during the first century AD, Celsus credits the Greeks with the first description of a varicocele, and he recorded his own acute observation: "The veins are swollen and twisted over the testicle, which becomes smaller". Celsus himself is credited with the distinction between varicocele (dilation of surface veins) and "cirsocele" (dilation of deep veins). There has been a long history of treatment attempts and failures, some of which are remarkably strange, that have sometimes culminated in tragedy, as in the case of French professor Jacques-Mathieu Delpech (1772- 1832)...
March 23, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29551581/injuries-in-the-greek-epics-of-homer
#8
Nikitas Nomikos
Trauma and the need of medical care exist since the beginning of human history. This research is aimed to identify and analyze trauma in antiquity. After a review of bibliography, the first reports of trauma (in Europe) were found in the Greek Epics of Homer. The analysis of these texts showed that injury could be caused to any part of the human body. The main cause of trauma was primarily participation in wars (178 cases), and then participation in sports (6 cases) and other activities (6 cases). This study identified a total of 190 injuries in both Homer epics...
April 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29533340/auricular-clyster-otenchytes-and-pyoulcos-precursors-of-the-ear-syringe
#9
Nathalie Rousseau, Albert Mudry
OBJECTIVES/HYPOTHESIS: In Western medicine, the long history of the ear syringe dates back at least to the end of the 1st millennium BCE; but the corresponding Ancient Greek word surinx designates another tool. Other Greek and Latin words and phrases, in particular auricular clyster, otenchytes, and pyoulcos, were known as names of the ear syringe until modern times. The aim of this article is to study the Greek and Latin words and phrases referred to as names of the ear syringe up until modern times before syringe became the standard word...
April 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29529680/-gallstones-and-liver-obstruction-in-medical-texts-of-antiquity
#10
Frank Ursin, Florian Steger
INTRODUCTION: Gallstones are rarely mentioned in the medical texts of antiquity. The physician, Alexander of Tralles mentions-for the first time-stones in the gallbladder as a possible cause for obstructive jaundice. This designation is found in his textbook on medicine under the heading "obstruction of the liver". Based on that observation, we describe the ancient history of hepatic obstruction and investigate the connection with the rare reference of gallstones in the medical texts of antiquity...
March 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29516691/-on-the-considerations-about-heating-materials-and-temperature-of-moxibustion-in-clinical-practice
#11
Bing Zhu
Moxibustion, one of the traditional Chinese medicine therapy, plays an important role in the treatment of a variety of clinical conditions, particularly the chronic and deficiency problems. In the present paper, the author reviewed the history of development of moxibustion therapy, and the related materials and heating temperature in ancient China, and also reviewed the history of heating therapy (similar to moxibustion) appearing in ancient Egypt, Greek, Libya, India, Europe, etc. The author thinks that the efficacy of moxibustion intervention mainly depends on the heating temperature and the heated area of the skin (not the heating materials) according to his own research group's experimental outcomes...
February 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29455442/in-search-of-executive-impairment-in-pathological-gambling-a-neuropsychological-study-on-non-treatment-seeking-gamblers
#12
Alexandros Kapsomenakis, Panagiotis G Simos, Georgios Konstantakopoulos, Dimitrios S Kasselimis
Pathological gambling is characterized by a persisting maladaptive and recurrent behavior with severe social and psychological consequences. There is evidence of strong comorbidity with psychiatric manifestations as well as cognitive mainly involving executive functions. This study aimed to investigate impairment in executive functions and working memory, and personality traits in a sample of Greek gamblers. Twenty-four men involved in various gambling activities were recruited from ecological settings as probable pathological gamblers...
February 17, 2018: Journal of Gambling Studies
https://www.readbyqxmd.com/read/29413399/roots-of-mediterranean-civilisations
#13
Michael Gross
European culture traces its history back to the ancient Greek civilisations, while Christianity and Judaism have their roots in the populations on the eastern shore of the Mediterranean Sea. Genome studies of several Bronze Age individuals from each of these regions have now probed the genetic roots of early civilisations, revealing both migration and continuity in both cases. Michael Gross reports.
September 25, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29406301/the-history-of-mind-psyche-body-soma-medicine-practical-examples
#14
Paulo Nuno Martins
This article discusses the relationship between health and disease, considering the mind/body dichotomy that has occurred in the history of medicine, both in Western and Eastern cultures. The author begins by referring to the magical concept of disease, passing through the classical Greek period, and the medieval and Renaissance vision, to the evolution of modern concepts proposed by psychoanalysis. The author references some practical examples about the importance of the mind-body relationship, such as the psychological steps experienced by the oncological patient, as well as the psychiatric disorder...
January 2018: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/29405895/problem-drinking-among-at-risk-college-students-the-examination-of-greek-involvement-freshman-status-and-history-of-mental-health-problems
#15
Haley S Martinez, Alicia K Klanecky, Dennis E McChargue
OBJECTIVE: Scarce research has examined the combined effect of mental health difficulties and demographic risk factors such as freshman status and Greek affiliation in understanding college problem drinking. The current study is interested in looking at the interaction among freshman status, Greek affiliation, and mental health difficulties. PARTICIPANTS AND METHODS: Undergraduate students (N = 413) from a private and public Midwestern university completed a large online survey battery between January 2009 and April 2013...
February 6, 2018: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29392977/assessment-of-association-between-lipoxygenase-genes-variants-in-elderly-greek-population-and-type-2-diabetes-mellitus
#16
Xanthippi A Tsekmekidou, Kalliopi D Kotsa, Fotis S Tsetsos, Triantafyllos P Didangelos, Marianthi A Georgitsi, Athanasios K Roumeliotis, Stylianos A Panagoutsos, Elias D Thodis, Marios T Theodoridis, Nikolaos P Papanas, Dimitrios A Papazoglou, Ploumis S Pasadakis, Maltezos S Eustratios, Peristera I Paschou, John G Yovos
BACKGROUND: Inflammation plays a pivotal role in the pathogenesis of diabetes and its complications. Arachidonic acid lipoxygenases have been intensively studied in their role in inflammation in metabolic pathways. Thus, we aimed to explore variants of lipoxygenase genes (arachidonate lipoxygenase genes) in a diabetes adult population using a case-control study design. METHODS: Study population consisted of 1285 elderly participants, 716 of whom had type 2 diabetes mellitus...
February 1, 2018: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29390534/toe-keloid-after-nail-extraction-treated-with-surgical-excision-a-case-report
#17
Hao Liu, Kexin Song, Mingzi Zhang, Xinhang Dong, Shu Liu, Youbin Wang
RATIONALE: In this study, a case of toe keloid after nail extraction is presented, in which the keloids on both toes were resected by surgical excision. Keloids (from the Greek word meaning "crab's claw") are fibrous growths that extend beyond the original area of injury to involve the adjacent normal skin. In general, keloid tendencies appear to be regionally isolated to keloid-prone areas, such as the chest, ears, and deltoid regions, whereas the hands and feet are usually spared, which is why this case is meaningful...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29335925/germline-deleterious-mutations-in-genes-other-than-brca2-are-infrequent-in-male-breast-cancer
#18
Florentia Fostira, Emmanouil Saloustros, Paraskevi Apostolou, Andromahi Vagena, Despoina Kalfakakou, Davide Mauri, Dimitrios Tryfonopoulos, Vassileios Georgoulias, Drakoulis Yannoukakos, Georgios Fountzilas, Irene Konstantopoulou
PURPOSE: Male breast cancer (MBC) is a rare cancer entity, with mutations in BRCA1 and BRCA2 genes accounting for ~ 10% of patients. Multiple-gene sequencing has already entered clinical practice for female breast cancer, whereas the performance of panel testing in MBC has not been studied extensively. Therefore, the aim of this study was to evaluate the clinical utility of panel testing for MBC, by the largest gene panel used so far, through investigation of patients deriving from a population with known founder effects...
May 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29327131/renal-vein-thrombosis-complicating-severe-acute-pyelonephritis-with-renal-abscesses-and-associated-bacteraemia-caused-by-extended-spectrum-beta-lactamase-producing-escherichia-coli
#19
Stelios F Assimakopoulos, Pantelis Kraniotis, Charalambos Gogos, Markos Marangos
Acute pyelonephritis might be complicated by the formation of renal and perirenal abscesses and very rarely by renal vein thrombosis, which is a life-threatening condition. The main causative agents of acute pyelonephritis are enterobacteriaceae with the incidence of extended-spectrum beta-lactamase (ESBL)-producing strains increasing worldwide. We present the case of a 71-year-old Greek man with history of diabetes mellitus and recent hospitalization, who suffered from severe pyelonephritis with renal abscesses formation and associated bacteraemia caused by ESBL-producing Escherichia coli, complicated by extensive thrombosis of the ipsilateral renal vein and its branches, protruding also in the inferior venal cava...
May 2018: CEN Case Reports
https://www.readbyqxmd.com/read/29317314/phi-in-physiology-psychology-and-biomechanics-the-golden-ratio-between-myth-and-science
#20
REVIEW
Marco Iosa, Giovanni Morone, Stefano Paolucci
In recent years, there has been a renewed interest in the use of the so-called golden ratio (Phi, ϕ), an irrational number with fractal properties, used in artworks since V century BC. and now for modelling complex biological structures and functions. This number, in fact, recursively pops-up in human history, from Ancient Greeks to Renaissance, and to contemporary scientific studies. Nevertheless, recent scientific results often fall between two extremes: those of a priori sceptic researchers accusing the artificial emergence of ϕ in many studies, and those of researchers that find a mystic meaning in the presence of ϕ in human physiology...
March 2018: Bio Systems
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