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https://www.readbyqxmd.com/read/28210753/puerarin-7-o-glucuronide-a-water-soluble-puerarin-metabolite-prevents-angiotensin-ii-induced-cardiomyocyte-hypertrophy-by-reducing-oxidative-stress
#1
Ning Hou, Bin Cai, Cai-Wen Ou, Zhen-Hui Zhang, Xia-Wen Liu, Mu Yuan, Gan-Jian Zhao, Shi-Ming Liu, Long-Gen Xiong, Jian-Dong Luo, Cheng-Feng Luo, Min-Sheng Chen
This study aimed to investigate the anti-oxidant and anti-hypertrophic effects of puerarin-7-O-glucuronide, a water-soluble puerarin metabolite. The anti-oxidant effects of puerarin-7-O-glucuronide were assessed by measurement of intracellular superoxide levels, total superoxide dismutase (SOD) activity, total anti-oxidant capacity, and glutathione (GSH)/glutathione disulfide (GSSG) ratio in cultured neonatal rat cardiomyocytes (NRCMs) stimulated with the xanthine oxidase (XO)/xanthine (X) system or angiotensin II...
February 16, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28210534/psychological-adjustment-among-young-puerto-rican-mothers-perceived-partner-support-and-the-moderating-role-of-latino-cultural-orientation
#2
Josefina M Grau, Patricia Castellanos, Erin N Smith, Petra A Duran, Stephanie Silberman, Lauren Wood
Adolescent mothers face multiple stressors and are at risk for experiencing high levels of depressive symptoms and parenting stress. This study examined the interplay of Latino cultural orientation and perceived support from romantic partners in protecting the adjustment of young, low-income, Puerto Rican mothers (N = 103; M age = 18.0 yrs; SD = 1.2) during the second year postpartum. In multivariate analyses, perceived partner support was uniquely and negatively associated with both maternal depressive symptoms and parenting stress...
2017: Journal of Latina/o Psychology
https://www.readbyqxmd.com/read/28208966/study-of-parental-perceptions-on-health-social-needs-of-children-with-neuro-developmental-disability-and-it-s-impact-on-the-family
#3
Nusrat Jahan Rafique Ansari, Ramchandra Keshav Dhongade, Preeti Sagar Lad, Ashwin Borade, Suvarna Yg, Vishal Yadav, Ashwini Mehetre, Rahul Kulkarni
INTRODUCTION: The term Neuro Developmental Disorder (NDD) is used for conditions caused by a dysfunction in any part of the brain or nervous system, resulting in physical and/or psychological symptoms as a child develops. Family of children with NDD face many problems. It is very important to find them and create awareness so that gaps in essential services and supports can be decreased. AIM: To explore parental perceptions on health & social needs of children with NDD, to understand the impact of disability on the families having children with disability, and to find out the parental perceptions on availability of services for children with NDD and its utilization by families...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207843/allergic-rhinitis-atopic-dermatitis-and-asthma-are-associated-with-differences-in-school-performance-among-korean-adolescents
#4
So Young Kim, Min-Su Kim, Bumjung Park, Jin-Hwan Kim, Hyo Geun Choi
Several studies have reported negative relations between allergic diseases and school performance but have not simultaneously considered various allergic diseases, including allergic rhinitis, asthma, and atopic dermatitis, and only examined a limited number of participants. The present study investigated the associations of allergic rhinitis, asthma, and atopic dermatitis with school performance in a large, representative Korean adolescent population. A total of 299,695 7th through 12th grade students participated in the Korea Youth Risk Behaviour Web-based Survey (KYRBWS) from 2009 to 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28207579/expansion-of-prosodic-abilities-at-the-transition-from-babble-to-words-a-comparison-between-children-with-cochlear-implants-and-normally-hearing-children
#5
Michèle Pettinato, Ilke De Clerck, Jo Verhoeven, Steven Gillis
OBJECTIVES: This longitudinal study examined the effect of emerging vocabulary production on the ability to produce the phonetic cues to prosodic prominence in babbled and lexical disyllables of infants with cochlear implants (CI) and normally hearing (NH) infants. Current research on typical language acquisition emphasizes the importance of vocabulary development for phonological and phonetic acquisition. Children with CI experience significant difficulties with the perception and production of prosody, and the role of possible top-down effects is, therefore, particularly relevant for this population...
February 15, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28207571/systematic-review-of-interventions-to-reduce-psychiatric-morbidity-in-parents-and-children-after-picu-admissions
#6
Samantha C Baker, Julia A Gledhill
OBJECTIVE: To describe and evaluate interventions aimed at reducing psychiatric morbidity in parents and children discharged from PICU. DATA SOURCES: A systematic review of the literature was undertaken, searching EMBASE, PSYCHinfo, MEDLINE, and CINAHL. Experts in the field were contacted to identify unpublished studies. STUDY SELECTION: Exclusion criteria: Studies with participants above age 18 or drawn from a neonatal ICU, studies not in English, and those not measuring psychopathology...
February 15, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28205453/how-taiwanese-parents-of-children-with-autism-spectrum-disorder-experience-the-process-of-obtaining-a-diagnosis-a-descriptive-phenomenological-analysis
#7
Kuo-Yu Chao, Hsueh-Ling Chang, Wei-Chih Chin, Hsin-Mei Li, Sue-Hsien Chen
An autism spectrum disorder can result in considerable stress and confusion for parents as they attempt to understand their child's problems and obtain a diagnosis. Few studies have explored the parental experience in the context of Chinese culture. The purpose of this study was to understand the experiences of parents in Taiwan of children diagnosed with autism spectrum disorder. In total, 15 parents, 1 father and 14 mothers, were recruited by purposive sampling. This qualitative study used semi-structured interviews and descriptive phenomenological analysis...
February 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28202252/what-worries-parents-of-a-child-with-autism-evidence-from-a-biomarker-for-chronic-stress
#8
Vicki Bitsika, Christopher F Sharpley, Nicholas M Andronicos, Linda L Agnew
BACKGROUND: Previous studies have reported correlations between various aspects of the behaviour and symptomatology of children with Autism Spectrum Disorder (ASD) and their parents' self-reports of stress via standardised scales. AIMS: To extend that literature, a physiological index of parental chronic stress was used instead of their self-reports-dysregulation of the Diurnal Rhythm (DR) of the Hypothalamic-Pituitary-Adrenal (HPA) axis. METHODS: A sample of 149 parents of a child with ASD provided salivary cortisol at the predicted time of daily maximum cortisol concentration and at a time of daily lower concentration...
February 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28202249/mutual-expectations-of-mothers-of-hospitalized-children-and-pediatric-nurses-who-provided-care-qualitative-study
#9
Dilek Konuk Şener, Aysel Karaca
PURPOSE: This study attempted to identify the mutual expectations of mothers whose children were hospitalized in the pediatric department of a university hospital and nurses who provided care. DESIGN AND METHODS: A descriptive phenomenological design has been used in this study. Data were obtained through tape-recorded semi-structured interviews. This study was conducted at a pediatric clinic, at a university hospital in a small city in Turkey. Participants comprised five nurses working in the children's clinic and 24 mothers who accompanied their children to the hospital...
February 12, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28201945/maternal-adhd-symptoms-and-parenting-stress
#10
David Williamson, Charlotte Johnston
OBJECTIVE: ADHD symptoms in adults are consistently related to stress in a variety of domains, although whether the link between ADHD symptoms and stress is direct, or accounted for or moderated by other variables, is little studied. We used a cross-sectional design to examine whether parenting self-efficacy accounts for the relation between maternal ADHD symptoms and parenting stress, and whether levels of maternal neuroticism moderate this relation. METHOD: A nonclinical sample of mothers of 120, six- to 12-year-old children completed surveys online...
February 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28199920/family-burden-child-disability-and-the-adjustment-of-mothers-caring-for-children-with-epilepsy-role-of-social-support-and-coping
#11
Jeffrey M Carlson, Paul A Miller
PURPOSE: This study was designed to contribute to the existing research on the coping behaviors, social support, and mental health outcomes in parents of children with epilepsy in the United States. METHODS: Participants included 152, predominantly Caucasian (89.5%), married (78.9%) women (95.4%). Via a web-based interface, mothers completed questionnaires assessing the impact of their child's disability on their family (i.e., severity of their child's disability, family burden, and personal stress), social resources (i...
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28199857/socioeconomic-status-hair-cortisol-and-internalizing-symptoms-in-parents-and-children
#12
Alexandra Ursache, Emily C Merz, Samantha Melvin, Jerrold Meyer, Kimberly G Noble
Socioeconomic disadvantage is consistently linked with higher risk for internalizing problems, and stress is likely one important mechanism explaining this increased risk. Few studies have examined socioeconomic differences in hair cortisol, a novel biomarker of long-term adrenocortical activity and chronic stress. Moreover, no studies have examined whether differences in hair cortisol might explain socioeconomic disparities in internalizing problems. To address these gaps, we first examined relations of socioeconomic status (SES; family income and parental education) to variation in both parents' and children's hair cortisol concentrations (HCC) and then tested whether HCC and perceptions of stress mediated relations of SES to parents' and children's internalizing symptoms...
January 28, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28198942/normative-analysis-of-the-voice-of-children-in-brazilian-child-protection-legislation
#13
Renata de Moura Bubadué, Ivone Evangelista Cabral, Franco Carnevale, Felipe Dutra Asensi
Objective: to identify and analyse children's voices in healthcare decision making in the discourse of Brazil's child protection laws. Method: Documentary normative analysis of Brazil's child protection legislation (1988-2012) based on the content analysis of nine texts, conducted in 2015. Results: The legislation acknowledges and stresses the voice of children in the decision-making process in research and healthcare. Any recognition of the right to dignity, liberty, information, and protection depends on what the adult decision-maker (with parental authority) believes is the child's capacity for discernment and whether the situation will cause self-harm...
February 9, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28197994/a-population-based-comparison-of-female-and-male-same-sex-parent-and-different-sex-parent-households
#14
Henny M W Bos, Lisette Kuyper, Nanette K Gartrell
This investigation compared Dutch same-sex parent and different-sex parent households on children's psychological well-being, parenting stress, and support in child rearing. It was also assessed whether associations among children's well-being, parenting stress, and support in child rearing were different in the two household types. Data were based on a nationally representative survey (N = 25,250). Matching was used to enhance similarity in background characteristics between both types of families. Parental and child characteristics were matched for 43 female same-sex parent, 52 male same-sex parent, and 95 different-sex parent households with offspring between 5 and 18 years old...
February 15, 2017: Family Process
https://www.readbyqxmd.com/read/28196348/investigation-of-implicit-avoidance-of-displacement-related-stimuli-in-offspring-of-trauma-exposed-forcibly-displaced-individuals
#15
Charlotte E Wittekind, Christoph Muhtz, Steffen Moritz, Lena Jelinek
There is an ongoing debate as to whether traumatization also affects the close relatives of trauma survivors who have symptoms of PTSD. Although many studies provide evidence favoring a transgenerational transmission, other studies have not found evidence to support this idea. The present study examined whether adult offspring of individuals exposed to trauma during forced displacement with (n=22) and without PTSD (n=24) exhibit an implicit avoidance of stimuli related to the parental trauma compared to children of non-trauma exposed control participants (n=23) using an Approach-Avoidance task (AAT)...
February 3, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28194315/screening-of-faba-bean-vicia-faba-l-accessions-to-acidity-and-aluminium-stresses
#16
Kiflemariam Y Belachew, Frederick L Stoddard
BACKGROUND: Faba bean is an important starch-based protein crop produced worldwide. Soil acidity and aluminium toxicity are major abiotic stresses affecting its production, so in regions where soil acidity is a problem, there is a gap between the potential and actual productivity of the crop. Hence, we set out to evaluate acidity and aluminium tolerance in a range of faba bean germplasm using solution culture and pot experiments. METHODS: A set of 30 accessions was collected from regions where acidity and aluminium are or are not problems...
2017: PeerJ
https://www.readbyqxmd.com/read/28194158/role-and-regulation-of-acc-deaminase-gene-in-sinorhizobium-meliloti-is-it-a-symbiotic-rhizospheric-or-endophytic-gene
#17
Alice Checcucci, Elisa Azzarello, Marco Bazzicalupo, Anna De Carlo, Giovanni Emiliani, Stefano Mancuso, Giulia Spini, Carlo Viti, Alessio Mengoni
Plant-associated bacteria exhibit a number of different strategies and specific genes allow bacteria to communicate and metabolically interact with plant tissues. Among the genes found in the genomes of plant-associated bacteria, the gene encoding the enzyme 1-aminocyclopropane-1-carboxylate (ACC) deaminase (acdS) is one of the most diffused. This gene is supposed to be involved in the cleaving of plant-produced ACC, the precursor of the plant stress-hormone ethylene toning down the plant response to infection...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28193207/a-novel-point-mutation-in-rpob-improves-osmotolerance-and-succinic-acid-production-in-escherichia-coli
#18
Mengyong Xiao, Xinna Zhu, Hongtao Xu, Jinlei Tang, Ru Liu, Changhao Bi, Feiyu Fan, Xueli Zhang
BACKGROUND: Escherichia coli suffer from osmotic stress during succinic acid (SA) production, which reduces the performance of this microbial factory. RESULTS: Here, we report that a point mutation leading to a single amino acid change (D654Y) within the β-subunit of DNA-dependent RNA polymerase (RpoB) significantly improved the osmotolerance of E. coli. Importation of the D654Y mutation of RpoB into the parental strain, Suc-T110, increased cell growth and SA production by more than 40% compared to that of the control under high glucose osmolality...
February 13, 2017: BMC Biotechnology
https://www.readbyqxmd.com/read/28191460/assessment-of-influences-of-stenoses-in-right-carotid-artery-on-left-carotid-artery-using-wall-stress-marker
#19
Arindam Bit, Dushali Ghagare, Albert A Rizvanov, Himadri Chattopadhyay
Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region of bifurcation. Such morphological change in vessel largely affects parent as well as corresponding sister and daughter vessels. In this paper, complexity in hemodynamic of blood in pair of carotid arteries (left and right carotid arteries) is evaluated in presence of stenoses at basilar segment of right artery in three-dimensional domain using reconstructed tomographic images of patient...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28190946/effects-of-pmto-in-foster-families-with-children-with-behavior-problems-a-randomized-controlled-trial
#20
Anne M Maaskant, Floor B van Rooij, Geertjan J Overbeek, Frans J Oort, Maureen Arntz, Jo M A Hermanns
The present randomized controlled trial examined the effectiveness of Parent Management Training Oregon for foster parents with foster children (aged 4-12) with severe externalizing behavior problems in long-term foster care arrangements. Foster children's behavior problems are challenging for foster parents and increase the risk of placement breakdown. There is little evidence for the effectiveness of established interventions to improve child and parent functioning in foster families. The goal of Parent Management Training Oregon, a relatively long and intensive (6-9 months, with weekly sessions) parent management training, is to reduce children's problem behavior through improvement of parenting practices...
2017: Journal of Child and Family Studies
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