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https://www.readbyqxmd.com/read/28522906/magnetic-anchor-guidance-for-endoscopic-submucosal-dissection-and-other-endoscopic-procedures
#1
REVIEW
Mohamed Mortagy, Neal Mehta, Mansour A Parsi, Seiichiro Abe, Tyler Stevens, John J Vargo, Yutaka Saito, Amit Bhatt
Endoscopic submucosal dissection (ESD) is a well-established, minimally invasive treatment for superficial neoplasms of the gastrointestinal tract. The universal adoption of ESD has been limited by its slow learning curve, long procedure times, and high risk of complications. One technical challenge is the lack of a second hand that can provide traction, as in conventional surgery. Reliable tissue retraction that exposes the submucosal plane of dissection would allow for safer and more efficient dissection...
April 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28521616/a-10-gene-classifier-for-indeterminate-thyroid-nodules-development-and-multicenter-accuracy-study
#2
Hernan E Gonzalez, Jose R Martínez, Sergio Vargas, Antonieta Solar, Loreto Pamela Véliz, Francisco Cruz, Tatiana Arias, Soledad Loyola, Eleonora Horvath, Hernán Tala, Eufrosina Traipe, Manuel Meneses, Luis Marin, Nelson Wohllk, Rene Eduardo Diaz, Jesús Véliz, Pedro Pineda, Patricia Arroyo, Natalia Mena, Milagros Bracamonte, Giovanna Miranda, Elsa Bruce, Soledad Urra
BACKGROUND: In most of the world, diagnostic surgery remains as the most frequent approach for indeterminate thyroid cytology. Although several molecular tests are available for central-lab testing in the US, there are no available kits for local laboratory testing. The aim of this study was to develop a prototype in-vitro diagnostic (IVD) gene classifier for diagnosis of indeterminate thyroid cytology. METHODS: In a first stage, the expression of 18 genes was determined by qPCR in a broad histopathological spectrum of fresh tissue biopsies (114)...
May 18, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28516295/judgments-of-differences-and-ratios-of-subjective-heaviness
#3
Sergio Cesare Masin, Andrea Brancaccio
Experimental instructions to judge differences or ratios of subjective heaviness numerically are generally assumed to produce judgments linearly proportional to the respective heaviness differences or heaviness ratios. In this study, participants were instructed to numerically judge the difference or ratio of heaviness between two weights being lifted separately, either unimanually or bimanually. Weight values were combined factorially. Patterns of factorial curves revealed that unimanual lifting triggered linear judgments of heaviness differences, whereas bimanual lifting triggered nonlinear judgments of heaviness ratios...
May 17, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28514940/the-effect-of-initial-teaching-on-evaluation-of-left-ventricular-volumes-by-cardiovascular-magnetic-resonance-imaging-comparison-between-complete-and-intermediate-beginners-and-experienced-observers
#4
Erik Hedström, Masaki Ishida, Alvaro Sepúlveda-Martínez, Daniel Salehi, Johannes Sperling, Henrik Engblom, Eike Nagel
BACKGROUND: High reproducibility and low intra- and interobserver variability are important strengths of cardiac magnetic resonance (CMR). In clinical practice a significant learning curve may however be observed. Basic CMR courses offer an average of 1.4 h dedicated to lecturing and demonstrating left ventricular (LV) function analysis. The purpose of this study was to evaluate the effect of initial teaching on complete and intermediate beginners' quantitative measurements of LV volumes and function by CMR...
May 17, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28512778/cagi4-crohn-s-exome-challenge-marker-snp-versus-exome-variant-models-for-assigning-risk-of-crohn-disease
#5
Lipika R Pal, Kunal Kundu, Yizhou Yin, John Moult
Understanding the basis of complex trait disease is a fundamental problem in human genetics. The CAGI Crohn's Exome challenges are providing insight into the adequacy of current disease models by requiring participants to identify which of a set of individuals has been diagnosed with the disease, given exome data. For the CAGI4 round, we developed a method that used the genotypes from exome sequencing data only to impute the status of Genome Wide Association Studies (GWAS) marker single nucleotide polymorphisms (SNPs)...
May 16, 2017: Human Mutation
https://www.readbyqxmd.com/read/28512777/the-australian-laparoscopic-radical-prostatectomy-learning-curve
#6
Marcus Handmer, Charles Chabert, Ronald Cohen, Troy Gianduzzo, Paul Kearns, Daniel Moon, Jason Ooi, Tom Shannon, David Sofield, Andrew Tan, Mark Louie-Johnsun
BACKGROUND: International estimates of the laparoscopic radical prostatectomy (LRP) learning curve extend to as many as 1000 cases, but is unknown for Fellowship-trained Australian surgeons. METHODS: Prospectively collected data from nine Australian surgeons who performed 2943 consecutive LRP cases was retrospectively reviewed. Their combined initial 100 cases (F100, n = 900) were compared to their second 100 cases (S100, n = 782) with two of nine surgeons completing fewer than 200 cases...
May 16, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28511971/learning-curve-for-the-endoscopic-endonasal-approach-for-suprasellar-craniopharyngiomas
#7
Hailin Ding, Ye Gu, Xiaobiao Zhang, Tao Xie, Tengfei Liu, Fan Hu, Yong Yu, Chongjing Sun
The endoscopic endonasal approach is considered an alternative minimally invasive approach for suprasellar craniopharyngiomas. However, the complicated surgical manipulations required by this approach have limited its application. We evaluate whether the approach features a learning curve. Thirty-three patients were retrospectively reviewed and grouped as early (17 patients) and late (16 patient) groups. The operation time, extent of removal, ophthalmology, endocrinology, reconstruction and modifications of standard technique were evaluated...
May 13, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28511894/incorporating-simulation-into-gynecologic-surgical-training
#8
REVIEW
Kyle Wohlrab, J Eric Jelovsek, Deborah Myers
Today's educational environment has made it more difficult to rely on the Halstedian model of 'see one, do one, teach one' in gynecologic surgical training. There is decreased surgical volume, but an increased number of surgical modalities. Fortunately, surgical simulation has evolved to fill the educational void. Whether it is through skill generalization or skill transfer, surgical simulation has shifted the learning curve from the operating room back to the classroom. This article explores the principles of surgical education and ways to introduce simulation as an adjunct to residency training...
May 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28509905/crowdsourced-validation-of-a-machine-learning-classification-system-for-autism-and-adhd
#9
M Duda, N Haber, J Daniels, D P Wall
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) together affect >10% of the children in the United States, but considerable behavioral overlaps between the two disorders can often complicate differential diagnosis. Currently, there is no screening test designed to differentiate between the two disorders, and with waiting times from initial suspicion to diagnosis upwards of a year, methods to quickly and accurately assess risk for these and other developmental disorders are desperately needed...
May 16, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28508418/quantitative-analysis-of-the-cervical-texture-by-ultrasound-in-the-mid-pregnancy-is-associated-with-spontaneous-preterm-birth
#10
Núria Baños, Alvaro Perez-Moreno, Carla Julià, Clara Murillo-Bravo, David Coronado, Eduard Gratacos, Jan Deprest, Montse Palacio
OBJECTIVE: New tools are required to identify women at increased risk of spontaneous preterm birth (sPTB). Quantitative texture analysis by ultrasound has been used to extract robust features from the ultrasound image of a given tissue to detect subtle changes in its microstructure. This may also be applied to the cervix. We aimed to determine if there is an association between quantitative analysis of the cervical texture (CTx) by ultrasound in the mid-trimester of pregnancy and sPTB <37(+0) weeks...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28505969/early-detection-of-learning-difficulties-when-confronted-with-novel-information-in-preclinical-alzheimer-s-disease-stage-1
#11
Adrià Tort-Merino, Natalia Valech, Claudia Peñaloza, Petra Grönholm-Nyman, María León, Jaume Olives, Ainara Estanga, Mirian Ecay, Juan Fortea, Pablo Martínez-Lage, Jose L Molinuevo, Matti Laine, Antoni Rodríguez-Fornells, Lorena Rami
We employed a highly demanding experimental associative learning test (the AFE-T) to explore memory functioning in Preclinical Alzheimer's Disease stage 1 (PreAD-1) and stage 2 (PreAD-2). The task consisted in the learning of unknown object/name pairs and our comprehensive setup allowed the analysis of learning curves, immediate recall, long-term forgetting rates at one week, three months, and six months, and relearning curves. Forty-nine cognitively healthy subjects were included and classified according to the presence or absence of abnormal CSF biomarkers (Control, n = 31; PreAD-1, n = 14; PreAD-2, n = 4)...
May 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28505691/laparoscopic-pyloromyotomy-a-study-of-the-learning-curve
#12
Aurélien Binet, François Bastard, Pierre Meignan, Karim Braïk, Anne Le Touze, Thierry Villemagne, Baptiste Morel, Michel Robert, Clémence Klipfel, Hubert Lardy
No abstract text is available yet for this article.
May 15, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28505037/getting-ready-for-the-first-robotic-prostatectomy-from-basics-to-real-practice
#13
Christian Wagner, Victor Srougi, Rafael Sanchez-Salas
PURPOSE OF REVIEW: Robot-assisted radical prostatectomy (RARP) has been embraced by urologists and has become a treatment standard in many countries already. Learning how to perform a RARP is challenging and has not yet been standardized. The current review summarizes the latest concepts regarding the most effective way of training for RARP. RECENT FINDINGS: The strategy to learn RARP should comprise didactic activities, skills lab training, participating in surgeries and mentorship...
May 12, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28504556/evolution-of-technique-in-laparoscopic-donor-nephrectomy-a-single-center-experience
#14
Davide Cintorino, Duilio Pagano, Pasquale Bonsignore, Fabrizio di Francesco, Sergio Li Petri, Calogero Ricotta, Salvatore Gruttadauria
BACKGROUND: Renal transplantation is the most successful therapy for improving survival and quality of life for end-stage renal disease (ESRD). Living donor kidney transplantation (LDKTx) has been used as an alternative to reduce the stay on the waiting list of patients with ESRD. Laparoscopic donor nephrectomy (LDN) has become the standard procedure for LDKTx. OBJECTIVE: This study aims to describe evolution of surgical technique with LDN at our institute. MATERIALS AND METHODS: We retrospectively analyzed our experience with LDN performed from January, 2003 to November, 2016, focusing on describing modifications of the surgical technique and devices made during those years...
May 15, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28503572/learning-curve-and-clinical-outcomes-of-performing-surgery-with-the-intertan-intramedullary-nail-in-treating-femoral-intertrochanteric-fractures
#15
A-Bing Li, Wei-Jiang Zhang, Ji-Qi Wang, You-Ming Zhao, Wei-Jun Guo
Purpose. The purpose of this study is to evaluate the learning curve of performing surgery with the InterTan intramedullary nail in treating femoral intertrochanteric fractures, to provide valuable information and experience for surgeons who decide to learn a new procedure. Methods. We retrospectively analyzed data from 53 patients who underwent surgery using an InterTan intramedullary nail at our hospital between July 2012 and September 2015. The negative exponential curve-fit regression analysis was used to evaluate the learning curve...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28502359/pearls-and-pitfalls-for-a-surgeon-new-to-ankle-replacements
#16
REVIEW
Federico Giuseppe Usuelli, Camilla Maccario
The role of the surgeon learning curve in total ankle replacement (TAR) has produced contradictory results. It is important for a new surgeon to know what clinical and radiological parameters are considered reliable and ideal. It is clear that exposure to a high-volume center will increase the reliability of a new surgeon approaching TAR. Implant choice may be influenced by surgeon training, and the debate of mobile versus fix-bearing prosthesis is still open. Anterior versus lateral approach is still an open debate, with any hypothetical advantages given by the direct vision on the center of rotation to be proven...
June 2017: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/28501246/advances-in-laparoscopic-colorectal-surgery
#17
REVIEW
James Michael Parker, Timothy F Feldmann, Kyle G Cologne
Laparoscopic colorectal surgery has now become widely adopted for the treatment of colorectal neoplasia, with steady increases in utilization over the past 15 years. Common minimally invasive techniques include multiport laparoscopy, single-incision laparoscopy, and hand-assisted laparoscopy, with the choice of technique depending on several patient and surgeon factors. Laparoscopic colorectal surgery involves a robust learning curve, and fellowship training often lays the foundation for a high-volume laparoscopic practice...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28500580/is-right-colectomy-a-complete-learning-procedure-for-a-robotic-surgical-program
#18
Paolo Raimondi, Francesco Marchegiani, Massimo Cieri, Annadomenica Cichella, Roberto Cotellese, Paolo Innocenti
This study analyses the utility of right colectomy as a learning procedure at the beginning of a robotic surgical program. The hypothesis is that right colectomy contains all the technical steps necessary to acquire basic abilities in robotics surgery. The first 23 consecutive robotic right colectomy performed at the beginning of a robotic program were analysed. All surgical times were recorded in the operating room and second checked on a dedicated video-database. Specific robotic times were analysed using CUSUM method to evaluate the learning curve...
May 12, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28499617/community-based-outcomes-of-open-versus-robot-assisted-radical-prostatectomy
#19
Annika Herlemann, Janet E Cowan, Peter R Carroll, Matthew R Cooperberg
BACKGROUND: Identifying the optimal surgical approach for patients with localized prostate cancer (PCa) managed in the community setting remains controversial due to the lack of robust, prospective data. OBJECTIVE: To assess surgical outcomes and changes in urinary and sexual quality of life (QOL) over time in patients undergoing radical prostatectomy (RP). DESIGN, SETTING, AND PARTICIPANTS: Our study included patients enrolled in Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE), a large, prospective, mostly community-based, nationwide PCa registry, who underwent RP between 2004 and 2016...
May 9, 2017: European Urology
https://www.readbyqxmd.com/read/28494994/predicting-return-visits-to-the-emergency-department-for-pediatric-patients-applying-supervised-learning-techniques-to-the-taiwan-national-health-insurance-research-database
#20
Ya-Han Hu, Chun-Tien Tai, Solomon Chih-Cheng Chen, Hai-Wei Lee, Sheng-Feng Sung
BACKGROUND AND OBJECTIVE: Return visits (RVs) to the emergency department (ED) consume medical resources and may represent a patient safety issue. The occurrence of unexpected RVs is considered a performance indicator for ED care quality. Because children are susceptible to medical errors and utilize considerable ED resources, knowing the factors that affect RVs in pediatric patients helps improve the quality of pediatric emergency care. METHODS: We collected data on visits made by patients aged ≤18years to EDs from the National Health Insurance Research Database...
June 2017: Computer Methods and Programs in Biomedicine
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