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https://www.readbyqxmd.com/read/29687867/cryoablation-for-atrial-fibrillation-and-antiarrhythmic-drug-pretreatment-a-single-referral-center-experience
#1
M Spartalis, E Tzatzaki, E Spartalis, D Moris, I Doulamis, A S Triantafyllis, E Livanis, G Theodorakis
OBJECTIVE: Pulmonary vein isolation (PVI) ablation has emerged as the gold standard of ablative strategies to treat medically refractory paroxysmal and persistent atrial fibrillation (AF). Regardless of the superiority of catheter ablation based on PVI over antiarrhythmic drug therapy, recurrence rates of AF remain higher than desired. PVI via cryoablation has rapidly become a mainstream treatment for AF, due to its effectiveness and fast learning curve. Our objective was to assess the safety and efficacy of cryoablation in a single referral center...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29686870/practical-techniques-in-cryoballoon-ablation-how-to-isolate-inferior-pulmonary-veins
#2
Shaojie Chen, Boris Schmidt, Stefano Bordignon, Fabrizio Bologna, Takahiko Nagase, Laura Perrotta, K R Julian Chun
Catheter ablation is the most effective treatment option for patients suffering from symptomatic atrial fibrillation. Electrical isolation of the pulmonary veins is the procedural cornerstone. Point-by-point radiofrequency current energy ablation in combination with a 3D electro-anatomical mapping system is the established approach to ablation. In contrast, cryoballoon ablation uses a single-shot approach to facilitate pulmonary vein isolation. However, fixed cryoballoon diameters (28 mm or 23 mm) and non-balloon compliance can lead to technical difficulties in isolating variable pulmonary vein anatomies...
March 2018: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29684838/-doing-it-for-real-now-the-transition-from-healthcare-assistant-to-newly-qualified-nurse-a-qualitative-study
#3
Jan Draper
BACKGROUND: There has been increasing international research and policy interest concerning the transition from student to newly qualified nurse (NQN). However, the influence of previous employment as a healthcare assistant (HCA) on students' experiences of this transition is comparatively under-researched. AIMS AND OBJECTIVES: To explore the experiences of NQNs also employed as HCAs during their pre-registration education programme and how this prior and ongoing HCA experience influenced their transition experiences...
April 16, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29684663/predictive-features-for-early-cancer-detection-in-barrett-s-esophagus-using-volumetric-laser-endomicroscopy
#4
Fons van der Sommen, Sander R Klomp, Anne-Fré Swager, Svitlana Zinger, Wouter L Curvers, Jacques J G H M Bergman, Erik J Schoon, Peter H N de With
The incidence of Barrett cancer is increasing rapidly and current screening protocols often miss the disease at an early, treatable stage. Volumetric Laser Endomicroscopy (VLE) is a promising new tool for finding this type of cancer early, capturing a full circumferential scan of Barrett's Esophagus (BE), up to 3-mm depth. However, the interpretation of these VLE scans can be complicated, due to the large amount of cross-sectional images and the subtle grayscale variations. Therefore, algorithms for automated analysis of VLE data can offer a valuable contribution to its overall interpretation...
April 13, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29684001/one-hundred-and-fifteen-cases-of-pure-laparoscopic-living-donor-right-hepatectomy-at-a-single-center
#5
Kwang-Woong Lee, Suk Kyun Hong, Kyung-Suk Suh, Hyo-Sin Kim, Sung-Woo Ahn, Kyung Chul Yoon, Jeong-Moo Lee, Jae-Hyung Cho, Hyeyoung Kim, Nam-Joon Yi
BACKGROUND: The pure laparoscopic approach to donor hepatectomy is being taken more often. However, few centers perform pure laparoscopic donor right hepatectomy (PLDRH) because it requires a high level of surgical skill. Studies reporting initial outcomes of PLDRH may prompt further implementation of the technique and help reduce initial learning curves at other transplant centers. This study reports performance of PLDRH at a single center with extensive experience of adult living donor liver transplantation...
April 21, 2018: Transplantation
https://www.readbyqxmd.com/read/29683877/robotic-assisted-infrarenal-para-aortic-lymphadenectomy-in-gynecological-cancers-technique-and-surgical-outcomes
#6
Minna M Mäenpää, Kari Nieminen, Eija I Tomás, Tiina H Luukkaala, Johanna U Mäenpää
OBJECTIVE: Mini-invasive surgery has essentially replaced open laparotomy in surgery for endometrial and cervical carcinoma. Of the procedures needed for a complete staging, especially para-aortic lymphadenectomy (PALND) is challenging to perform. The present study was undertaken to investigate the technical and surgical outcomes of robotic-assisted PALND for gynecological cancers in the setting of a tertiary university hospital in Finland. METHODS: This was a retrospective chart review of 283 robotic-assisted para-aortic lymphadenectomies using the single-docking transperitoneal technique performed at the Department of Obstetrics and Gynecology of Tampere University Hospital, in 2009-2016...
April 21, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29682474/pancreaticoduodenectomy-minimizing-the-learning-curve
#7
Levan Tsamalaidze, John A Stauffer
Background: Pancreaticoduodenectomy outcomes improve as surgeon experience increases. We analyzed the outcomes of pancreaticoduodenectomy for any improvements over time to assess the learning curve. Methods: A retrospective study of patients undergoing consecutive pancreaticoduodenectomy by a single surgeon at the beginning of practice was performed. Operative factors and 90-day outcomes were examined and trends over the course of the 4-year time period were analyzed...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29682471/hybrid-thoracoabdominal-aortic-aneurysm-repair-is-the-future-here
#8
REVIEW
Vicente Orozco-Sevilla, Scott A Weldon, Joseph S Coselli
Open surgical repair has been the gold standard for thoracoabdominal aortic aneurysm (TAAA) repair for more than 6 decades, but 2 additional options have emerged: total endovascular TAAA repair and a hybrid approach that combines open and endovascular repair. Despite the optimism for an endovascular approach, long-term results for these repairs are still lacking. Some of the issues with this emerging technology include the risk of paraplegia after extensive endovascular repair, the need for multiple reinterventions, continuous stent-graft surveillance, endograft branch stenosis, as well as the significant learning curve...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29682463/reasons-for-conversion-during-vats-lobectomy-what-happens-with-increased-experience
#9
REVIEW
Dario Amore, Davide Di Natale, Roberto Scaramuzzi, Carlo Curcio
Although controlled studies have demonstrated the benefits of a minimally invasive approach for pulmonary lobectomy over thoracotomy, reports have also documented that significant complications can occur during thoracoscopic lobectomy and sometimes require planned or emergent conversion to open surgery. Several authors have identified and reported causes and implications of intraoperative conversion to thoracotomy using different types of classification. The aim of this single centre retrospective review is to evaluate how the reasons for conversion change with increased experience, dividing patients who were converted to thoracotomy during video-assisted thoracic surgery (VATS) lobectomy, between 2011 and 2017, in two groups: those treated during learning curve (LC group) and those treated after learning curve (ALC group)...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29681877/perceptual-reorganization-of-lexical-tones-effects-of-age-and-experimental-procedure
#10
Antonia Götz, H Henny Yeung, Anna Krasotkina, Gudrun Schwarzer, Barbara Höhle
Findings on the perceptual reorganization of lexical tones are mixed. Some studies report good tone discrimination abilities for all tested age groups, others report decreased or enhanced discrimination with increasing age, and still others report U-shaped developmental curves. Since prior studies have used a wide range of contrasts and experimental procedures, it is unclear how specific task requirements interact with discrimination abilities at different ages. In the present work, we tested German and Cantonese adults on their discrimination of Cantonese lexical tones, as well as German-learning infants between 6 and 18 months of age on their discrimination of two specific Cantonese tones using two different types of experimental procedures...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29680949/local-staging-with-multiparametric-mri-in-daily-clinical-practice-diagnostic-accuracy-and-evaluation-of-a-radiologic-learning-curve
#11
B H E Jansen, F H K Oudshoorn, A M Tijans, M J Yska, A P Lont, E R P Collette, J A Nieuwenhuijzen, A N Vis
PURPOSE: To estimate the diagnostic accuracy of multiparametric MRI (mpMRI) for the detection of locally advanced prostate cancer (T-stage 3-4) prior to radical prostatectomy, in a multicenter cohort representing daily clinical practice. In addition, the radiologic learning curve for the detection of locally advanced disease is evaluated. METHODS: Preoperative mpMRI findings of 430 patients (2012-2016) were compared to pathology results following radical prostatectomy...
April 21, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29679185/comparing-learning-curves-of-two-established-single-shot-devices-for-ablation-of-atrial-fibrillation
#12
Patrick Leitz, G Mönnig, F Güner, D G Dechering, K Wasmer, F Reinke, Philipp S Lange, L Eckardt, G Frommeyer
PURPOSE: We compared the contour of learning curves of two "single-shot" devices used for pulmonary vein isolation (PVI) for safety and procedural data. METHODS: We performed a retrospective analysis comparing the first 60 PVI performed at our center using a pulmonary vein ablation catheter (PVAC) array (39 male, mean age 57 years, 42 paroxysmal AF) to the first 60 first PVI using the Cryoballoon (44 male, mean age 59 years, 22 paroxysmal AF). Both groups were further divided into tertiles, where T1 regroups the first 20 ablations, T2 the following 20, and T3 the last 20 ablations...
April 20, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29676699/everted-suturing-of-the-inferior-vena-cava-is-addressed-in-the-abdominal-mouse-heart-transplant-model
#13
Hui Ren, Jiabin Zhang, Hongbo Wang, Shaotang Zhou
OBJECTIVES: Our objective was to investigate the techniques of vessel suturing in the abdominal mouse cardiac transplant model and animal outcomes. MATERIALS AND METHODS: Our mouse group included 92 female inbred mice, in which 46 abdominal mouse heart transplants were performed. During transplant, the openings for the aorta and the inferior vena cava were not parallel. With everted anastomosis, the ascending aortae and the pulmonary arteries of donors were connected to the abdominal aortae and interior vena cavae of recipients, respectively, with 11-0 Prolene suture...
April 20, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29675649/an-easier-lichtenstein-hernioplasty
#14
L Zogbi
BACKGROUND: The Lichtenstein technique is used worldwide because of its rapid learning curve, good results and low recurrence rates. In this approach, a lateral tie-shaped incision is made on the mesh, involving the spermatic funiculus and thus correcting the deep inguinal ring defect by narrowing it. The lateral tie, however, does not prevent the wrinkling of the upper portion of the mesh that is caused by the arched shape of the inguinal ligament, where the lower edge of the prosthesis is sutured...
April 19, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29674843/intraoperative-complications-of-refractive-small-incision-lenticule-extraction-in-the-early-learning-curve
#15
Abdelmonem M Hamed, Shereef M Abdelwahab, Tarek T Soliman
Purpose: To study the intraoperative complications of refractive small incision lenticule extraction (ReSMILE push-up technique), and to record the mean intraoperative duration time of all surgeries for the refractive surgeon in his early learning curve. Setting: Ebsar Eye Center, Benha, Egypt. Design: A prospective, single-center, cohort clinical study. Methods: This prospective, single-center, cohort clinical study was done on patients with myopia and myopic astigmatism, who were enrolled for SMILE surgeries...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29673945/three-dimensional-texture-analysis-with-machine-learning-provides-incremental-predictive-information-for-successful-shock-wave-lithotripsy-in-patients-with-kidney-stones
#16
Manoj Mannil, Jochen von Spiczak, Thomas Hermanns, Cédric Poyet, Hatem Alkadhi, Christian Daniel Fankhauser
PURPOSE: To determine the predictive value of three-dimensional texture analysis (3D-TA) in computed tomography (CT) images for successful shock wave lithotripsy (SWL) in patients with kidney stones. MATERIAL AND METHODS: Patients with pre and postoperative CT scans, previously untreated kidney stones and a stone diameter of 5-20 mm were included. A total of 224 3D-TA features of each kidney stone, including the attenuation measured in Hounsfield Units (HU), and the clinical variables body mass index (BMI), initial stone size, and skin-to-stone distance (SSD) were analyzed using five commonly used machine learning models...
April 16, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29672663/analysis-of-long-noncoding-rnas-highlights-region-specific-altered-expression-patterns-and-diagnostic-roles-in-alzheimer-s-disease
#17
Meng Zhou, Hengqiang Zhao, Xinyu Wang, Jie Sun, Jianzhong Su
Increasing evidence has revealed the multiple roles of long noncoding RNAs (lncRNAs) in neurodevelopment, brain function and aging, and their dysregulation was implicated in many types of neurological diseases. However, expression pattern and diagnostic role of lncRNAs in Alzheimer's disease (AD) remain largely unknown and has gained significant attention. In this study, we performed a comparative analysis for lncRNA expression profiles in four brain regions in brain aging and AD. Our analysis revealed age- and disease-dependent region-specific lncRNA expression patterns in aging and AD...
April 17, 2018: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/29672639/computer-aided-diagnosis-of-lung-nodule-using-gradient-tree-boosting-and-bayesian-optimization
#18
Mizuho Nishio, Mitsuo Nishizawa, Osamu Sugiyama, Ryosuke Kojima, Masahiro Yakami, Tomohiro Kuroda, Kaori Togashi
We aimed to evaluate a computer-aided diagnosis (CADx) system for lung nodule classification focussing on (i) usefulness of the conventional CADx system (hand-crafted imaging feature + machine learning algorithm), (ii) comparison between support vector machine (SVM) and gradient tree boosting (XGBoost) as machine learning algorithms, and (iii) effectiveness of parameter optimization using Bayesian optimization and random search. Data on 99 lung nodules (62 lung cancers and 37 benign lung nodules) were included from public databases of CT images...
2018: PloS One
https://www.readbyqxmd.com/read/29672420/the-arrival-of-robotics-in-spine-surgery-a-review-of-the-literature
#19
Alexander Ghasem, Akhil Sharma, Dylan N Greif, Milad Alam, Motasem Al Maaieh
STUDY DESIGN: Systematic Review. OBJECTIVE: The authors aim to review comparative outcome measures between robotic and free-hand spine surgical procedures including: accuracy of spinal instrumentation, radiation exposure, operative time, hospital stay, and complication rates. SUMMARY OF BACKGROUND DATA: Misplacement of pedicle screws in conventional open as well as minimally invasive surgical procedures has prompted the need for innovation and allowed the emergence of robotics in spine surgery...
April 18, 2018: Spine
https://www.readbyqxmd.com/read/29672344/preoperative-predictive-factors-of-conversions-in-laparoscopic-splenectomies
#20
Rosario Vecchio, Sebastian M Milluzzo, Graziano Troina, Emma Cacciola, Rossella R Cacciola, Renato S Catalano, Marco Caputo
PURPOSE: Presently, laparoscopic splenectomy (LS) is being performed for several indications in clinical practice. However, conversion to open surgery is occasionally required in some patients. We analyzed the intraoperative indications and potential preoperative predictors associated with conversion to open surgery in those presenting for LS. METHODS: We reviewed 107 patients who underwent LS. We analyzed the surgical indications, spleen size, surgical procedure performed, operative time, rate of and indications for conversions, as well as postoperative complications...
April 18, 2018: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
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