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https://www.readbyqxmd.com/read/29924203/descemet-membrane-endothelial-keratoplasty-dmek-intraoperative-and-postoperative-complications-and-clinical-results
#1
Yusuf Koçluk, Burcu Kasım, Emine Alyamaç Sukgen, Ayşe Burcu
PURPOSE: To evaluate the complications and clinical results of Descemet membrane endothelial keratoplasty (DMEK) in patients with endothelial failure that occurred during the learning curve of a surgeon. METHODS: Fifty eyes of 50 patients with DMEK and ≥6 months of follow-up were included. The patients were divided into the first 25 (group 1) and the second 25 (group 2) procedures performed by the surgeon. Best corrected visual acuity (BCVA), central corneal thickness (CCT), unfolding time of the Descemet membrane (DM) graft, and intraoperative and postoperative complications were compared between groups...
June 2018: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29916888/a-single-surgeon-s-experience-with-transgender-female-to-male-chest-surgery
#2
David M Whitehead, Paul R Weiss, Dina Podolsky
BACKGROUND: Chest wall recontouring is a common surgical treatment of gender dysphoria in transmen and nonbinary individuals assigned female at birth. This study reviews more than 20 years of cases to identify risk factors for postoperative complications and likelihood of preservation of nipple sensation. METHODS: One hundred thirty-seven cases of female-to-male chest wall recontouring by a single surgeon from 1994 to 2016 were reviewed, 99 of which were included for final analysis...
June 19, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29916881/design-conduct-and-analysis-of-surgical-randomized-controlled-trials-a-cross-sectional-survey
#3
Jiajie Yu, Wenwen Chen, Shidong Chen, Pengli Jia, Guanyue Su, Youping Li, Xin Sun
BACKGROUND: Randomized controlled trial (RCT) testing surgical intervention faced challenges due to complexities of surgery and made it more difficult for surgeons and methodologists than pharmaceutical providers to build a well-design, conduct RCT. OBJECTIVE: We conducted a cross-sectional survey to address the methodological challenges of RCTs on surgical intervention and offer potential solutions. METHODS: We searched PubMed in order to summarize 2-arm parallel randomized trials for surgical interventions published in 2013...
June 18, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29916040/minimal-invasive-gastrectomy-what-the-west-can-learn-from-the-east
#4
REVIEW
Felix Berlth, Han-Kwang Yang
Minimal-invasive gastrectomy has been established as commonly used method for the early gastric cancer in Korea and Japan. From the first laparoscopic cancer gastrectomy in 1992 in Japan, numerous prospective randomized trials from these two countries have gained the evidence for non-inferiority or even specific benefits compared to open surgery. In Korea, the "Korean Laparoscopic Gastrointestinal Surgical Study Group" (KLASS group) founded, in 2004, successfully gained evidence not only in regards of oncological safety of laparoscopic gastrectomy, but also for the impact of different reconstruction methods and alternative extents of luminal resection on postoperative outcome and quality of life...
June 18, 2018: Updates in Surgery
https://www.readbyqxmd.com/read/29915476/robotic-pancreaticoduodenectomy-technical-considerations
#5
Marco Marino, Gaspare Gulotta, Andrzej L Komorowski
Robotic surgery can help to overcome some technical limitations of laparoscopic pancreaticoduodenectomy thanks to EndoWrist instrumentations and the 3D view. Despite the potential benefits, its employment is still low and controversial. We focused on some important technical details crucial for a safe robotic pancreatectomy. After performing 52 robotic pancreatic resections that included 10 pancreatoduodenectomies, the authors describe their technique. The review of literature on robotic and laparoscopic duodenopancreatectomy is also performed in order to evaluate possible benefits of the robotic platform...
April 2018: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29914866/diagnostic-accuracy-of-a-machine-learning-approach-to-coronary-computed-tomographic-angiography-based-fractional-flow-reserve-result-from-the-machine-consortium
#6
Adriaan Coenen, Young-Hak Kim, Mariusz Kruk, Christian Tesche, Jakob De Geer, Akira Kurata, Marisa L Lubbers, Joost Daemen, Lucian Itu, Saikiran Rapaka, Puneet Sharma, Chris Schwemmer, Anders Persson, U Joseph Schoepf, Cezary Kepka, Dong Hyun Yang, Koen Nieman
BACKGROUND: Coronary computed tomographic angiography (CTA) is a reliable modality to detect coronary artery disease. However, CTA generally overestimates stenosis severity compared with invasive angiography, and angiographic stenosis does not necessarily imply hemodynamic relevance when fractional flow reserve (FFR) is used as reference. CTA-based FFR (CT-FFR), using computational fluid dynamics (CFD), improves the correlation with invasive FFR results but is computationally demanding...
June 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29914350/evaluating-methods-of-inferring-gene-regulatory-networks-highlights-their-lack-of-performance-for-single-cell-gene-expression-data
#7
Shuonan Chen, Jessica C Mar
BACKGROUND: A fundamental fact in biology states that genes do not operate in isolation, and yet, methods that infer regulatory networks for single cell gene expression data have been slow to emerge. With single cell sequencing methods now becoming accessible, general network inference algorithms that were initially developed for data collected from bulk samples may not be suitable for single cells. Meanwhile, although methods that are specific for single cell data are now emerging, whether they have improved performance over general methods is unknown...
June 19, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29909757/pilot-study-detection-of-gastric-cancer-from-exhaled-air-analyzed-with-an-electronic-nose-in-chinese-patients
#8
Valérie N E Schuermans, Ziyu Li, Audrey C H M Jongen, Zhouqiao Wu, Jinyao Shi, Jiafu Ji, Nicole D Bouvy
The aim of this pilot study is to investigate the ability of an electronic nose (e-nose) to distinguish malignant gastric histology from healthy controls in exhaled breath. In a period of 3 weeks, all preoperative gastric carcinoma (GC) patients (n = 16) in the Beijing Oncology Hospital were asked to participate in the study. The control group (n = 28) consisted of family members screened by endoscopy and healthy volunteers. The e-nose consists of 3 sensors with which volatile organic compounds in the exhaled air react...
June 1, 2018: Surgical Innovation
https://www.readbyqxmd.com/read/29909703/commercial-slit-lamp-anterior-segment-photography-versus-digital-compact-camera-mounted-on-a-standard-slit-lamp-with-an-adapter
#9
Huw Oliphant, Alasdair Kennedy, Oliver Comyn, David J Spalton, Mayank A Nanavaty
PURPOSE: To compare slit lamp mounted cameras (SLC) versus digital compact camera (DCC) with slit-lamp adaptor when used by an inexperienced technician. METHODS: In this cross sectional study, where posterior capsule opacification (PCO) was used as a comparator, patients were consented for one photograph with SLC and two with DCC (DCC1 and DCC2), with a slit-lamp adaptor. An inexperienced clinic technician, who took all the photographs and masked the images, recruited one eye of each patient...
June 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29909667/haematomas-after-carotid-endarterectomy-can-be-reduced-by-direct-pressure-to-the-neck-postoperatively
#10
R Saghir, G Humm, T Rix
Introduction A recognised complication of carotid endarterectomy (CEA) is postoperative haematoma, which can threaten the airway. Previous studies have looked at medical methods of preventing this complication. This study aims to evaluate the impact of simple direct pressure postoperatively on the development of haematoma. Materials and methods From 2011 to 2016, 161 consecutive CEA were performed by a single surgeon or trainee under supervision. After 80 operations, the postoperative technique was altered, with additional pressure being applied by the surgeon to the skin incision from completion of suturing until each patient was awake in the recovery room...
June 18, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29909114/predicting-survival-from-large-echocardiography-and-electronic-health-record-datasets-optimization-with-machine-learning
#11
Manar D Samad, Alvaro Ulloa, Gregory J Wehner, Linyuan Jing, Dustin Hartzel, Christopher W Good, Brent A Williams, Christopher M Haggerty, Brandon K Fornwalt
OBJECTIVES: The goal of this study was to use machine learning to more accurately predict survival after echocardiography. BACKGROUND: Predicting patient outcomes (e.g., survival) following echocardiography is primarily based on ejection fraction (EF) and comorbidities. However, there may be significant predictive information within additional echocardiography-derived measurements combined with clinical electronic health record data. METHODS: Mortality was studied in 171,510 unselected patients who underwent 331,317 echocardiograms in a large regional health system...
June 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29908785/radio-pathomic-maps-of-epithelium-and-lumen-density-predict-the-location-of-high-grade-prostate-cancer
#12
Sean D McGarry, Sarah L Hurrell, Kenneth A Iczkowski, William Hall, Amy L Kaczmarowski, Anjishnu Banerjee, Tucker Keuter, Kenneth Jacobsohn, John D Bukowy, Marja T Nevalainen, Mark D Hohenwalter, William A See, Peter S LaViolette
PURPOSE: This study aims to combine multiparametric magnetic resonance imaging (MRI) and digitized pathology with machine learning to generate predictive maps of histologic features for prostate cancer localization. METHODS AND MATERIALS: Thirty-nine patients underwent MRI prior to prostatectomy. After surgery, tissue was sliced according to MRI orientation using patient-specific 3-dimensionally printed slicing jigs. Whole-mount sections were annotated by our pathologist and digitally contoured to differentiate the lumen and epithelium...
April 24, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29908365/the-optimal-viewing-position-effect-in-printed-versus-cursive-words-evidence-of-a-reading-cost-for-the-cursive-font
#13
Jérémy Danna, Delphine Massendari, Benjamin Furnari, Stéphanie Ducrot
Two eye-movement experiments were conducted to examine the effects of font type on the recognition of words presented in central vision, using a variable-viewing-position technique. Two main questions were addressed: (1) Is the optimal viewing position (OVP) for word recognition modulated by font type? (2) Is the cursive font more appropriate than the printed font in word recognition in children who exclusively write using a cursive script? In order to disentangle the role of perceptual difficulty associated with the cursive font and the impact of writing habits, we tested French adults (Experiment 1) and second-grade French children, the latter having exclusively learned to write in cursive (Experiment 2)...
June 13, 2018: Acta Psychologica
https://www.readbyqxmd.com/read/29907817/serum-proteomic-profiling-to-identify-biomarkers-of-premature-carotid-atherosclerosis
#14
Santosh D Bhosale, Robert Moulder, Mikko S Venäläinen, Juhani S Koskinen, Niina Pitkänen, Markus T Juonala, Mika A P Kähönen, Terho J Lehtimäki, Jorma S A Viikari, Laura L Elo, David R Goodlett, Riitta Lahesmaa, Olli T Raitakari
To evaluate the presence of serum protein biomarkers associated with the early phases of formation of carotid atherosclerotic plaques, label-free quantitative proteomics analyses were made for serum samples collected as part of The Cardiovascular Risk in Young Finns Study. Samples from subjects who had an asymptomatic carotid artery plaque detected by ultrasound examination (N = 43, Age = 30-45 years) were compared with plaque free controls (N = 43) (matched for age, sex, body weight and systolic blood pressure)...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907462/learning-curve-of-robotic-rectal-surgery-with-lateral-lymph-node-dissection-cumulative-sum-and-multiple-regression-analyses
#15
Kazushige Kawai, Keisuke Hata, Toshiaki Tanaka, Takeshi Nishikawa, Kensuke Otani, Koji Murono, Kazuhito Sasaki, Manabu Kaneko, Shigenobu Emoto, Hiroaki Nozawa
OBJECTIVE: This study aimed to assess the learning curve of robotic rectal surgery, a procedure that has gained increasing focus in recent years because it is expected that the advanced devices used in this approach provide advantages resulting in a shorter learning curve than that of laparoscopic surgery. However, no studies have assessed the learning curve of robotic rectal surgery, especially when lateral lymph node dissection is required. DESIGN: This was a nonrandomized, retrospective study from a single institution...
June 12, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29907209/using-artificial-intelligence-to-predict-prolonged-mechanical-ventilation-and-tracheostomy-placement
#16
Joshua Parreco, Antonio Hidalgo, Jonathan J Parks, Robert Kozol, Rishi Rattan
BACKGROUND: Early identification of critically ill patients who will require prolonged mechanical ventilation (PMV) has proven to be difficult. The purpose of this study was to use machine learning to identify patients at risk for PMV and tracheostomy placement. MATERIALS AND METHODS: The Multiparameter Intelligent Monitoring in Intensive Care III database was queried for all intensive care unit (ICU) stays with mechanical ventilation. PMV was defined as ventilation >7 d...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29905414/tips-for-pedal-access-technical-evolution-and-review
#17
Ansar Z Vance, Daniel A Leung, Timothy W Clark
Pedal access has become an indispensable technique for endovascular therapy of complex lower extremity peripheral vascular disease. From an option as a single access in a patient lacking traditional access approaches to a critical maneuver in combined antegrade-retrograde approaches during the treatment of complex chronic total occlusions, pedal access is an essential tool for any endovascular physician treating peripheral arterial disease. Anticipatory planning is critical in the successful utilization of pedal access...
June 14, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29905082/editorial-comment-on-learning-curves-and-timing-of-surgical-trials-robotic-kidney-transplantation-with-regional-hypothermia
#18
John Barry
No abstract text is available yet for this article.
June 15, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29903476/convolutional-neural-network-based-pso-for-lung-nodule-false-positive-reduction-on-ct-images
#19
Giovanni Lucca França da Silva, Thales Levi Azevedo Valente, Aristófanes Corrêa Silva, Anselmo Cardoso de Paiva, Marcelo Gattass
BACKGROUND AND OBJECTIVE: Detection of lung nodules is critical in CAD systems; this is because of their similar contrast with other structures and low density, which result in the generation of numerous false positives (FPs). Therefore, this study proposes a methodology to reduce the FP number using a deep learning technique in conjunction with an evolutionary technique. METHOD: The particle swarm optimization (PSO) algorithm was used to optimize the network hyperparameters in the convolutional neural network (CNN) in order to enhance the network performance and eliminate the requirement of manual search...
August 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29902096/achieving-the-learning-curve-in-laparoscopic-inguinal-hernia-repair-by-tapp-a-quality-improvement-study
#20
Umberto Bracale, Giovanni Merola, Antonio Sciuto, Giuseppe Cavallaro, Jacopo Andreuccetti, Giusto Pignata
BACKGROUND: More than 20 million patients worldwide undergo groin hernia repair annually. Every year more than 800,000 inguinal hernia repairs are performed in the United States alone. Since the first report by Ger et al. in 1990, laparoscopic inguinal hernia repair has gained wide acceptance due to its many advantages with more than 20% of inguinal hernias treated by this approach. The aim of our study is to estimate the number of cases needed over the course of a trainee's learning curve period to achieve stabilization of operating time and intra and post-operative complication rates when performing laparoscopic transabdominal preperitoneal hernia repair (TAPP)...
June 14, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
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