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Knee pain incidence

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https://www.readbyqxmd.com/read/28899843/a-machine-learning-approach-for-the-identification-of-new-biomarkers-for-knee-osteoarthritis-development-in-overweight-and-obese-women
#1
N Lazzarini, J Runhaar, A C Bay-Jensen, C S Thudium, S M A Bierma-Zeinstra, Y Henrotin, J Bacardit
OBJECTIVE: Knee osteoarthritis (OA) is among the higher contributors to global disability. Despite its high prevalence, currently, there is no cure for this disease. Furthermore, the available diagnostic approaches have large precision errors and low sensitivity. Therefore, there is a need for new biomarkers to correctly identify early knee OA. METHOD: We have created an analytics pipeline based on machine learning to identify small models (having few variables) that predict the 30-months incidence of knee OA (using multiple clinical and structural OA outcome measures) in overweight middle-aged women without knee OA at baseline...
September 9, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28888527/complications-following-harvesting-of-patellar-tendon-or-hamstring-tendon-grafts-for-anterior-cruciate-ligament-reconstruction-systematic-review-of-literature
#2
REVIEW
A Hardy, L Casabianca, K Andrieu, L Baverel, T Noailles
INTRODUCTION: Anterior cruciate ligament (ACL) reconstruction can be performed with an autograft, which is most often harvested from the patient's hamstring tendon (HT) or patellar tendon (PT). However, autograft harvesting leads to morbidity that is by no means insignificant.A systematic review of literature was performed to define the incidence of complications related to graft harvesting and the methods to prevent these complications. MATERIALS AND METHODS: In March 2017, a systemic review of literature was performed using the keywords"harvesting", "harvest", "morbidity", "complication", "cruciate ligament"...
September 6, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28869091/potential-functional-benefit-from-light-intensity-physical-activity-in-knee-osteoarthritis
#3
Daniel K White, Jungwha Lee, Jing Song, Rowland W Chang, Dorothy Dunlop
INTRODUCTION: Knee pain may preclude participation in higher intensity physical activity in people with knee osteoarthritis and benefits of light activity are unclear. The effect of replacing sedentary time with light intensity activity on incident functional limitation 2 years later was investigated. METHODS: Included were people with or at high risk of knee osteoarthritis without baseline functional limitation using data from the Osteoarthritis Initiative collected between August 2008 and July 2010...
August 28, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28852353/management-of-painful-patellar-clunk-and-crepitance-results-at-a-mean-follow-up-of-five-years
#4
J Joseph Gholson, Devon D Goetz, Robert W Westermann, John Hart, John J Callaghan
INTRODUCTION: Painful patellar clunk and crepitance (PCC) is a known complication of total knee arthroplasty (TKA) with posterior-stabilized designs. Arthroscopic management of PCC has been proposed as a treatment option for PCC. METHODS: We reviewed all cases of PCC from a consecutive single-surgeon series using a specific posterior stabilized (PS) design treated with arthroscopy for PCC. In a series of 1,488 TKA cases, forty-six patients (3.1%) were identified to have clinical signs and symptoms of PCC during post-operative clinic follow-up...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28835871/multimodal-pain-management-in-older-elective-arthroplasty-patients
#5
Elaine Brooks, Susan H Freter, Susan K Bowles, David Amirault
BACKGROUND: Pain management after elective arthroplasty in older adults is complicated due to the risk of undertreatment of postoperative pain and potential adverse effects from analgesics, notably opioids. Using combinations of analgesics has been proposed as potentially beneficial to achieve pain control with lower opioid doses. OBJECTIVE: We compared a multimodal pain protocol with a traditional one, in older elective arthroplasty patients, measuring self-rated pain, incidence of postoperative delirium, quantity and cost of opioid analgesics consumed...
September 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/28831821/long-term-outcomes-of-over-8-000-medial-oxford-phase-3-unicompartmental-knees-a-systematic-review
#6
Hasan R Mohammad, Louise Strickland, Thomas W Hamilton, David W Murray
Background and purpose - There is debate as to the relative merits of unicompartmental and total knee arthroplasty (UKA, TKA). Although the designer surgeons have achieved good results with the Oxford UKA there is concern over the reproducibility of these outcomes. Therefore, we evaluated published long-term outcomes of the Oxford Phase 3 UKA. Patients and methods - We searched databases to identify studies reporting ≥10 year outcomes of the medial Oxford Phase 3 UKA. Revision, non-revision, and re-operation rates were calculated per 100 component years (% pa)...
August 23, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28831552/safety-and-efficacy-of-bi-annual-intra-articular-lbsa0103-injections-in-patients-with-knee-osteoarthritis
#7
Jin Kyu Lee, Chong-Hyuk Choi, Kwang-Jun Oh, Hee-Soo Kyung, Ju-Hyung Yoo, Chul-Won Ha, Seong-Il Bin, Seung-Baik Kang, Myung Ku Kim, Ju-Hong Lee, Myung Chul Lee
The objective of this study is to assess the safety and efficacy of repeated intra-articular injection of high molecular weight hyaluronic acid (LBSA0103) at a 26-week interval, in patients with osteoarthritis of the knee. The study was an open-label, single arm, multicentre prospective trial conducted in patients with symptomatic knee osteoarthritis. The intervention consisted of two intra-articular injections of LBSA0103, with the second injection performed 26 weeks after the first injection. The primary outcome was the incidence of adverse drug reactions related to each injection...
August 22, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28831390/aquacel%C3%A2-ag-surgical-dressing-reduces-surgical-site-infection-and-improves-patient-satisfaction-in-minimally-invasive-total-knee-arthroplasty-a-prospective-randomized-controlled-study
#8
Feng-Chih Kuo, Bradley Chen, Mel S Lee, Shih-Hsiang Yen, Jun-Wen Wang
The use of modern surgical dressings to prevent wound complications and surgical site infection (SSI) after minimally invasive total knee arthroplasty (MIS-TKA) is lacking. In a prospective, randomized, controlled study, 240 patients were randomized to receive either AQUACEL Ag Surgical dressing (study group) or a standard dressing (control group) after MIS-TKA. The primary outcome was wound complication (SSI and blister). The secondary outcomes were wear time and number of dressing changes in the hospital and patient satisfaction (pain, comfort, and ease of use)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28821271/high-speed-resistance-training-and-balance-training-for-people-with-knee-osteoarthritis-to-reduce-falls-risk-study-protocol-for-a-pilot-randomized-controlled-trial
#9
Pazit Levinger, Jeremy Dunn, Nancy Bifera, Michael Butson, George Elias, Keith D Hill
BACKGROUND: The number of falls experienced by people with knee osteoarthritis (OA) is almost double the number experienced by people with no OA. The neuromuscular elements required to arrest a fall are more impaired in people with knee OA compared to their asymptomatic counterparts. Therefore, these elements may need to be incorporated into an exercise intervention to reduce the risk of falling. The aim of this study will be to examine the feasibility, safety and patient satisfaction of a high-speed resistance-training program, with and without balance exercises, in people with knee OA compared to a control group...
August 18, 2017: Trials
https://www.readbyqxmd.com/read/28819599/synovial-chondromatosis-a-rare-differential-diagnosis-of-hip-pain-in-a-child
#10
Manesh Chacko Philip, Sajeer Usman
INTRODUCTION: Primary synovial chondromatosis (SC) is a disease of the synovium occurring in the third to fifth decade of life with the peak incidence in the fifth decade and commonly involves the knee in 50% cases. The diagnosis of SC is primarily radiological and intraoperative. Primary SC of the hip is rare, and their prevalence is not known. CASE REPORT: A 7-year-old female child presented with pain and limp left hip for 6 weeks. She had a stiff hip gait. Clinical examination revealed a fixed abduction, flexion deformity, and restricted internal rotation with apparent lengthening of 2 cm...
March 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28802423/effectiveness-of-exchange-k-nail-and-augmented-plating-in-aseptic-femoral-diaphyseal-non-union
#11
K H Sancheti, Chetan Pradhan, Atul Patil, Chetan Puram, Parkalp Bharti, Parag Sancheti, Ashok Shyam
BACKGROUND: Femoral diaphyseal non-unions present difficult scenario to manage. There are multiple options but most of them still report varying incidences of failure. We combined the principles of augmented plating and exchange nailing and aim to study the effectiveness of this technique. METHOD: A retrospective study at a tertiary trauma centre was conducted. Seventy patients (60 men, 10 women), average age 40.7±15.27 years (range 18-81 years) with diaphyseal femoral fracture non-unions treated between July 2010 and January 2015 were reviewed...
August 2017: Injury
https://www.readbyqxmd.com/read/28789655/efficacy-and-safety-of-a-new-elastic-tourniquet-cuff-in-total-knee-arthroplasty-a-prospective-randomized-controlled-study
#12
O-Sung Lee, Myung Chul Lee, Hyuk-Soo Han
BACKGROUND: The effects of cuff shape, timing of tourniquet application, and automated systems using limb occlusion pressure (LOP) have been reported to minimize the appropriate tourniquet pressure. However, studies on the raw material of the cuff itself to reduce the complications related to the tourniquet have been very rarely reported. The purpose of this study is to report the efficacy and safety of a tourniquet system with a new elastic cuff in which pressure is set with LOP in total knee arthroplasty (TKA)...
August 8, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28772066/varus-thrust-and-incident-and-progressive-knee-osteoarthritis
#13
Leena Sharma, Alison H Chang, Rebecca D Jackson, Michael Nevitt, Kirsten C Moisio, Marc Hochberg, Charles Eaton, C Kent Kwoh, Orit Almagor, Jane Cauley, Joan S Chmiel
BACKGROUND: To determine if varus thrust, bowing-out of the knee during gait, i.e., the first appearance or worsening of varus alignment during stance, is associated with incident and progressive knee osteoarthritis (OA), we undertook an Osteoarthritis Initiative ancillary study. We further considered hypothesized associations adjusted for static alignment, anticipating some attenuation. METHODS: 2-3 trained examiners/site at 4 sites observed gait. In eligible knees, incident OA was analyzed as subsequent incident KL≥2, whole and partial-grade medial joint space narrowing (JSN), and annualized loss of joint space width (JSW), and progression as medial JSN and JSW loss...
August 3, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28767456/effects-of-anaesthesia-and-analgesia-on-long-term-outcome-after-total-knee-replacement-a-prospective-observational-multicentre-study
#14
Dario Bugada, Massimo Allegri, Marco Gemma, Andrea L Ambrosoli, Giuseppe Gazzerro, Fernando Chiumiento, Doriana Dongu, Fiorella Nobili, Andrea Fanelli, Paolo Ferrua, Massimo Berruto, Gianluca Cappelleri
BACKGROUND: Perioperative regional anaesthesia may protect from persistent postsurgical pain (PPSP) and improve outcome after total knee arthroplasty (TKA). OBJECTIVES: Aim of this study was to evaluate the impact of regional anaesthesia on PPSP and long-term functional outcome after TKA. DESIGN: A web-based prospective observational registry. SETTING: Five Italian Private and University Hospitals from 2012 to 2015. PATIENTS: Undergoing primary unilateral TKA, aged more than 18 years, informed consent, American Society of Anesthesiologists (ASA) physical status classes 1 to 3, no previous knee surgery...
August 1, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28757449/weight-loss-in-the-prevention-and-treatment-of-diabetes
#15
Linda M Delahanty
The American Diabetes Association nutrition and lifestyle recommendations for prediabetes and type 2 diabetes focus on losing 7% of body weight and increasing physical activity to at least 150minperweek. This emphasis is largely based on results of the Diabetes Prevention Program (DPP) and Look AHEAD (Action for Health in Diabetes) clinical trials. DPP demonstrated that a lifestyle intervention aimed at 7% weight loss and 150min of activity per week reduced diabetes incidence by 58% after 2.8years of follow-up and resulted in sustained improvements in hemoglobinA1c, blood pressure and lipid levels...
July 28, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28720145/slipped-capital-femoral-epiphysis-a-population-based-study
#16
Bengt Herngren, Margaretha Stenmarker, Ludek Vavruch, Gunnar Hagglund
BACKGROUND: Slipped capital femoral epiphysis (SCFE) is the most common hip disorder in children 9-15 years old. This is a population-based study in Sweden presenting the epidemiology for SCFE. METHODS: In a prospective cohort study, we analysed pre- and postoperative radiographs, medical records for all children treated for SCFE in Sweden 2007-2013, demographic data, severity of slip and surgical procedures performed. RESULTS: We identified 379 Swedish children with primary SCFE 2007-2013; 162 girls, median age 11...
July 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28682892/in-patients-undergoing-fast-track-total-knee-arthroplasty-addition-of-buprenorphine-to-a-femoral-nerve-block-has-no-clinical-advantage-a-prospective-double-blinded-randomized-placebo-controlled-trial
#17
RANDOMIZED CONTROLLED TRIAL
Rienk van Beek, Harry J Zonneveldt, Tjeerd van der Ploeg, Jeroen Steens, Phillip Lirk, Marcus W Hollmann
BACKGROUND: Several adjuvants have been proposed to prolong the effect of peripheral nerve blocks, one of which is buprenorphine. In this randomized double blinded placebo controlled trial we studied whether the addition of buprenorphine to a femoral nerve block prolongs analgesia in patients undergoing total knee arthroplasty in a fast track surgery protocol. METHODS: The treatment group (B) was given an ultrasound-guided femoral nerve block with ropivacaine 0...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28676900/serum-levels-of-the-bone-turnover-markers-dickkopf-1-osteoprotegerin-and-tnf-%C3%AE-in-knee-osteoarthritis-patients
#18
Sicong Min, Chao Wang, Wanli Lu, Zhihong Xu, Dongquan Shi, Dongyang Chen, Huajian Teng, Qing Jiang
Knee osteoarthritis (KOA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Several inflammatory markers and cartilage degradation products can be used as biomarkers in OA. The key factors of bone metabolism in normal joint bone, dickkopf-1 (DKK1) and osteoprotegerin (OPG), interact with Wnt signaling pathway, balancing between bone absorption and bone reconstruction. TNF-α is a key inducer of DKK-1, which belongs to the family of proteins involved in joint remodeling...
July 4, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28663349/a-nationwide-cohort-study-of-slipped-capital-femoral-epiphysis
#19
Daniel C Perry, David Metcalfe, Matthew L Costa, Tjeerd Van Staa
OBJECTIVES: To describe the epidemiology of slipped capital femoral epiphysis (SCFE), to examine associations with childhood obesity and socioeconomic deprivation, and to explore factors associated with diagnostic delays. DESIGN: Historic cohort study using linked primary and secondary care data from the Clinical Practice Research Datalink and Hospital Episode Statistics. SETTING: All contacts with healthcare services, including emergency presentations, outpatient appointments, inpatient admissions and primary care visits, within the UK National Health Service...
June 29, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28658096/is-pregabalin-effective-and-safe-in-total-knee-arthroplasty-a-prisma-compliant-meta-analysis-of-randomized-controlled-trials
#20
Chao Han, Ming-Jie Kuang, Jian-Xiong Ma, Xin-Long Ma
BACKGROUND: Pain management after total knee arthroplasty (TKA) varies and has been investigated for years. Pregabalin as an anticonvulsant agent that selectively affects the nociceptive process has been used for pain relief after operation. This meta-analysis was conducted to examine the evidence of pregabalin in TKA. METHODS: Systematic searches of all related literatures were conducted using the following databases: MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials...
June 2017: Medicine (Baltimore)
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