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Chun Long Liu, Ya Peng Li, Xue Qiang Wang, Zhi Jie Zhang
BACKGROUND The objectives of the present study were to examine the intra- and inter-operator reliability of the MyotonPRO device in quantifying the stiffness of the Achilles tendon and the device's ability to examine the modulation in stiffness of the Achilles tendon during ankle joint flexion. MATERIAL AND METHODS Twenty asymptomatic participants (10 males and 10 females; mean age: 25.0±3.1 years) were recruited for this study. The stiffness of the Achilles tendon was quantified using the MyotonPRO device...
July 14, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Diederik P J Smeeing, Jan P Briet, Charlotte S van Kessel, Michiel M Segers, Egbert J Verleisdonk, Luke P H Leenen, Roderick M Houwert, Falco Hietbrink
We have described the epidemiology of complications after surgical treatment of ankle fractures and assessed which factors are associated with the most frequent complications. We conducted a retrospective cohort study at 2 level 2 and 1 level 1 trauma center in a single trauma region in the Netherlands. The study variables were collected from the electronic medical patient records; all ankle fractures were classified using the Lauge-Hansen classification, and the complications were recorded. A total of 989 patients were included from 3 hospitals, with 173 complications in 156 patients (15...
July 10, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Tatsuya Maruhashi, Junko Soga, Noritaka Fujimura, Naomi Idei, Shinsuke Mikami, Yumiko Iwamoto, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Haruki Hashimoto, Yoshiki Aibara, Farina Mohamad Yusoff, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, Ayumu Nakashima, Chikara Goto, Hirofumi Tomiyama, Bonpei Takase, Takahide Kohro, Toru Suzuki, Tomoko Ishizu, Shinichiro Ueda, Tsutomu Yamazaki, Tomoo Furumoto, Kazuomi Kario, Teruo Inoue, Shinji Koba, Kentaro Watanabe, Yasuhiko Takemoto, Takuzo Hano, Masataka Sata, Yutaka Ishibashi, Koichi Node, Koji Maemura, Yusuke Ohya, Taiji Furukawa, Hiroshi Ito, Hisao Ikeda, Akira Yamashina, Yukihito Higashi
BACKGROUND: The usefulness of vascular function tests for management of patients with a history of coronary artery disease is not fully known. METHODS AND RESULTS: We measured flow-mediated vasodilation (FMD) and brachial-ankle pulse wave velocity (baPWV) in 462 patients with coronary artery disease for assessment of the predictive value of FMD and baPWV for future cardiovascular events in a prospective multicenter observational study. The first primary outcome was coronary events, and the second primary outcome was a composite of coronary events, stroke, heart failure, and sudden death...
July 12, 2018: Journal of the American Heart Association
Bart Dingenen, Christian Barton, Tessa Janssen, Anke Benoit, Peter Malliaras
OBJECTIVES: To examine test-retest reliability of two-dimensional measured frontal and sagittal plane kinematics during running, and to determine how many steps to include to reach and maintain a stable mean. DESIGN: Reliability study. SETTING: Research laboratory. PARTICIPANTS: Twenty-one recreational runners. MAIN OUTCOME MEASURES: Lateral trunk position, contralateral pelvic drop, femoral adduction, hip adduction, knee flexion and ankle dorsiflexion during midstance, and foot and tibia inclination at initial contact were measured with two-dimensional video analysis during running for 10 consecutive steps for both legs...
June 30, 2018: Physical Therapy in Sport
Jessica E Goetz, Nathan P Davidson, M James Rudert, Nicole Szabo, Matthew D Karam, Phinit Phisitkul
BACKGROUND: The purpose of this study was to compare mechanical behavior of conventional syndesmosis fixation devices with new anatomic repair techniques incorporating various repair augmentations to determine which approach would return rotational ankle mechanics closer to those of an intact ankle. METHODS: Ten pairs of fresh-frozen through-the-knee cadaveric lower limbs were subjected to 7.5 Nm of external rotation torque while under 750 N of axial compression...
July 1, 2018: Foot & Ankle International
Henryk Liszka, Artur Gądek
BACKGROUND: The main goal of the study was to evaluate the costs, clinical and radiologic results, and complications of hallux valgus surgery using scarf osteotomy, depending on the type of fixation (with or without screws). METHODS: We evaluated 169 patients who underwent scarf osteotomy between January 2013 and August 2016. The patients were separated into 3 groups depending on the type of stabilization: A, 2 screws (50 patients); B, modified with 1 screw (55 patients); C, modified without implant (64 patients)...
July 1, 2018: Foot & Ankle International
Yong Beom Kim, Hong-Seuk Yang, Ha Jung Kim, Hey-Ran Choi, Junyong In, Soon-Young Yoon, Young Jin Ro
This in-vivo study tested the hypothesis that the modulation of acetylcholine (ACh) release by the M1 muscarinic receptor (mAChR) in the neuromuscular junction of disused muscles may affect the tensions of the muscles during the neuromuscular monitoring of a rocuronium-induced neuromuscular block and compared the results with those obtained from normal muscles. A total of 20 C57BL/6 (wild-type) and 10 α7 knock out (α7KO) mice were used in this experiment. As a pre-experimental procedure, knee and ankle joints of right hind limbs were fixed by needle pinning at the 90° flexed position...
July 13, 2018: Clinical and Experimental Pharmacology & Physiology
Marina Hitz, Pascal Schütz, Michael Angst, William R Taylor, Renate List
Video-fluoroscopic analysis can provide important insights for the evaluation of outcome and functionality after total knee arthroplasty, allowing the in vivo assessment of tibiofemoral kinematics without soft tissue artefacts. To enable measurement of the knee throughout activities of daily living such as gait, robotic systems like the moving fluoroscope have been developed that follow the knee movement and maintain the joint in front of the image intensifier. Since it is unclear whether walking while being accompanied by moving fluoroscope affects normal gait, the objective of this study was to investigate its influence on gait characteristics in healthy subjects...
2018: PloS One
Minkyung Lee, Bom Soo Kim, Yeoju Kim, In Young Hyun
Heel pain is a common symptom in foot and ankle disorders. Typical heel pain can be assessed according to the patient's history and the location of pain. In some atypical inconclusive cases, bone SPECT/CT is the upcoming imaging modality for the detection of causes of heel pain. We present the case of 57-year-old man with atypical heel pain, plantar and Achilles spurs. SPECT/CT images demonstrated increased bony activity in arthritis of midfoot, not plantar and Achilles spurs. It suggests potential role of SPECT/CT in the evaluation and management of heel pain by showing hidden pathology of foot and ankle...
July 12, 2018: Clinical Nuclear Medicine
Jan H N Lindeman, Jaap Jan Zwaginga, Graziella Kallenberg-Lantrua, Rob C van Wissen, Abbey Schepers, Hajo J van Bockel, Willem E Fibbe, Jaap F Hamming
BACKGROUND AND AIMS: Prospects for no-option, end-stage peripheral artery disease (PAD) patients remain poor. Although results from open and semiblinded studies fuel hope for cell-based strategies in no-option patients, so far conclusions from the available placebo-controlled studies are not supportive. With the intention to end the remaining controversy with regard to cell therapy for PAD we conducted a confirmatory, double-blinded randomized placebo-controlled phase 3 trial. STUDY DESIGN: This randomized controlled trial was registered (NCT00539266)...
July 12, 2018: Annals of Surgery
Dong Liu, Weihai Chen, Kyuhwa Lee, Ricardo Chavarriaga, Fumiaki Iwane, Mohamed Bouri, Zhongcai Pei, Jose Del R Millan
Brain-machine interfaces (BMIs) have been used to incorporate the user intention to trigger robotic devices by decoding movement onset from electroencephalography (EEG). Active neural participation is crucial to promote brain plasticity thus to enhance the opportunity of motor recovery. This study presents the decoding of lower-limb movement-related cortical potentials (MRCPs) with continuous classification and asynchronous detection.We executed experiments in a customized gait trainer where 10 healthy subjects performed self-initiated ankle plantar flexion...
July 11, 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
F Tian, X-H Zang, Y-S Sun
OBJECTIVE: To investigate the impact of knee varus and valgus in varying degrees on the alignment in lower extremities of patients who received the total knee arthroplasty (TKA). PATIENTS AND METHODS: We retrospectively analyzed the condition of varus and valgus deformity in full-length X-ray films of double lower extremities in weight-bearing position of 120 patients before and after they firstly received the TKA between March 2012 and May 2014 to discover the impact of knee varus and valgus in varying degrees on the alignment in lower extremities of patients who received the total knee arthroplasty (TKA)...
July 2018: European Review for Medical and Pharmacological Sciences
Olivier Wijers, Rosa C Looijen, Jens A Halm, Tim Schepers
BACKGROUND: Peripheral fractures of the talus are uncommon. Almost all the literature regarding talar fractures consists of central intra-articular fractures, whereas studies about peripheral talar fractures are lacking. The aim of this study is to increase awareness in diagnosing an unusual peripheral extra-articular medial impression fracture of the talus. METHODS: This study includes a retrospective case series of patients with an extra-articular medial impression fracture of the talus...
July 1, 2018: Foot & Ankle Specialist
Daniel Neunhäuserer, Andrea Gasperetti, Sara Ortolan, Francesca Battista, Pietro Pettenella, Marco Zaccaria, Marco Bergamin, Andrea Ermolao
INTRODUCTION: Increased inter-arm systolic blood pressure difference (ΔPsys) has been associated with cardiovascular (CV) disease in elderly patients with CV risk factors. However, its significance in healthy subjects is unclear. AIM: To determine the relationship between ΔPsys, the individual level of physical activity and the global CV risk in apparently healthy adults. METHODS: Systolic blood pressure was measured in both arms in 400 subjects aged 46...
July 12, 2018: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
Jessica Trevino, Hyunglae Lee
Ankle stiffness has been known as one of the most important components contributing to the maintenance of lower body stability during postural balance and locomotion. It has been repeatedly shown that women have lower stability and increased risk of injury when compared to men participating in similar sports activities, yet sex differences in neuromuscular control of the ankle, including the modulation of ankle stiffness, and their contribution to stability remain unknown. To identify sex differences in human ankle stiffness, this study quantified multi-dimensional ankle stiffness in 20 young, healthy men and 20 young, healthy women over a range of ankle muscle contractions, from relaxed to 20% of maximum voluntary co-contraction of ankle muscles...
July 12, 2018: Annals of Biomedical Engineering
Kang Zheng, Zexu Chen, Wen Sun, Bin Liu, Danping Fan, Qingqing Guo, Hui Luo, Jiawen Shen, Li Li, Xiaojuan He, Shuang Kou, Xiaoya Li, Guoming Pang, Hongchuan Zhao, Cheng Lu
Rheumatoid arthritis (RA) is a type of chronic systemic inflammatory disease; it has a very complicated pathogenesis, and multiple pathological changes are implicated. Traditional Chinese medicine (TCM) like Tripterygium wilfordii Hook. F. or Sinomenium acutum (Thunb.) Rehd et Wils. has been extensively used for centuries in the treatment of arthritic diseases and been reported effective for relieving the severity of RA. Hei-Gu-Teng Zhuifenghuoluo granule (HGT) which contains Periploca forrestii Schltr. , Sinomenium acutum (Thunb...
2018: Journal of Immunology Research
Katherine C L Hillyard, Shabnam Shabbir, Udawattage Nadeeka Sirisena, Maxine Hogarth, Ajay Sahu
Insufficiency fractures are recognized but rare complications in patients with longstanding rheumatoid arthritis. Such fractures are typically solitary and are rarely seen to affect the foot and ankle. We describe 3 women with longstanding rheumatoid arthritis, treated with one, or a combination of, corticosteroids, DMARDs and anti-TNF, presenting with foot and ankle pain with no prior history of trauma. MRIs showed rare multiple florid insufficiency fractures of the foot and ankle, in 2 cases bilaterally, which were managed conservatively...
August 2018: Radiology Case Reports
Izabela Mróz, Piotr J Bachul, Krzysztof A Tomaszewski, Tomasz Bereza, Krzysztof Gil, Jerzy A Walocha, Artur Pasternak
Due to the lack of anatomical studies concerning complexity of the tibiofibular syndesmosis blood supply, density of blood vessels with further organization of syndesmotic vascular variations is presented in clinically relevant classification system. The material for the study was obtained from cadaveric dissections. We dissected 50 human ankles observing different types of arterial blood supply. Our classification system is based on the vascular variations of the anterior aspect of tibiofibular syndesmosis and corresponds with vascular density...
July 12, 2018: Scientific Reports
Soo Ji Jeon, Hae-Young Lopilly Park, Jae Hyung Lee, Chan Kee Park
Retinal nerve fiber layer (RNFL) loss in diabetic patients is especially common regardless of diabetic retinopathy (DR). The correlations between nonglaucomatous RNFL loss and systemic characteristics in diabetic patients have aroused interests in many aspects. 167 subjects with type 2 diabetes who underwent evaluation for arterial stiffness and cardiovascular autonomic function using heart rate variability (HRV) were included in this study. Arterial stiffness was measured using cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI)...
July 12, 2018: Scientific Reports
E Montefiori, L Modenese, R Di Marco, S Magni-Manzoni, C Malattia, M Petrarca, A Ronchetti, P van Dijkhuizen, M Viceconti, C Mazzà
Juvenile Idiopathic Arthritis (JIA) is a paediatric disease of unknown aetiology potentially leading to biomechanical alterations due to local damage of joints. After assessing its reliability, a patient-specific musculoskeletal model of the lower limb was used to investigate the link between joint loading and disease activity in a cohort of JIA children with ankle involvement. We observed a common strategy aiming at protecting the affected ankles with consequent overloading of hip and knee. When quantified at patient specific level, this strategy might allow to identify those cases where a localised steroid injection might not be sufficient to induce remission...
July 3, 2018: Gait & Posture
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