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https://www.readbyqxmd.com/read/27922864/99mtc-mdp-uptake-in-diffuse-pleural-recurrences-of-pulmonary-neuroendocrine-carcinoma
#1
Taisong Wang, Wenli Qiao, Yan Xing, Jinhua Zhao
A 39-year-old woman with a history of pulmonary neuroendocrine carcinoma segmental palliative resection underwent a Tc-MDP bone scintigraphy to evaluate possible osseous metastases. The static images revealed diffuse elevated activity in the left hemithorax, more prominent in the lower thorax, which is suggestive of malignant pleural effusion. However, SPECT/CT images showed that the elevated activity was from pleura-based soft tissue masses, which were confirmed as recurrent tumor pathologically after biopsy...
December 3, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27922152/diagnosis-of-chronic-osteomyelitis-by-combined-99m-tc-bone-and-99m-tc-anti-granulocyte-scintigraphy
#2
Anne Frölich, Gotthard Knoll, Manfred Bähre, Christoph Neumann
No abstract text is available yet for this article.
December 6, 2016: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/27920480/comparison-of-multichannel-intraluminal-impedance-ph-monitoring-and-reflux-scintigraphy-in-pediatric-patients-with-suspected-gastroesophageal-reflux
#3
Nuray Uslu Kızılkan, Murat Fani Bozkurt, Inci Nur Saltık Temizel, Hülya Demir, Aysel Yüce, Biray Caner, Hasan Özen
AIM: To evaluate the agreement of multichannel intraluminal impedance-pH monitoring (MII-pHM) and gastroesophageal reflux scintigraphy (GES) for the diagnosis of gastroesophageal reflux disease. METHODS: Seventy-five consecutive patients with suspected gastroesophageal reflux disease (GERD) underwent 24-h combined MII-pHM recording and one hour radionuclide scintigraphy during the course of the MII-pHM study. Catheters with 6 impedance channels and 1 pH sensor were placed transnasally...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27919970/11c-acetate-pet-ct-compared-to-99mtc-hdp-bone-scintigraphy-in-primary-staging-of-high-risk-prostate-cancer
#4
Sara Strandberg, Camilla Thellenberg Karlsson, Mattias Ogren, Jan Axelsson, Katrine Riklund
AIM: The aim of this study was to evaluate the detection rate of bone metastases and the added value of (11)C-acetate (ACE) positron-emission tomography/computed tomography (PET/CT) compared to bone scintigraphy (BS) in high-risk prostate cancer (PC). MATERIALS AND METHODS: A total of 66 untreated patients with high-risk PC with ACE-PET/CT and planar BS findings within 3 months of each other were retrospectively enrolled. Findings were compared and verified with follow-up data after an average of 26 months...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919134/-a-case-of-metastatic-tubulocystic-carcinoma-of-the-kidney-treated-with-molecularly-targeted-therapy
#5
Fumihiko Urabe, Jun Miki, Takafumi Yanagisawa, Takahiro Kimura, Masataka Nakano, Masafumi Suzuki, Koichi Kishimoto, Shin Egawa
A 51-year-old man who presented with gross hematuria and back pain was found to have a right renal mass accompanied with lung and osseous metastases. The patient underwent transabdominal right nephrectomy. The histopathological examination revealed the tumor to be tubulocystic carcinoma of the kidney. After the patient received sunitinib therapy, contrast enhanced computed tomography revealed that the metastatic tumor size was stable in the bone and decreased in the lung. Unfortunately, 9 months after nephrectomy, bone scintigraphy revealed an increase in the size of the metastatic tumor in the bone...
November 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27915009/exploring-gastrointestinal-variables-affecting-drug-and-formulation-behavior-methodologies-challenges-and-opportunities
#6
REVIEW
Bart Hens, Maura Corsetti, Robin Spiller, Luca Marciani, Tim Vanuytsel, Jan Tack, Arjang Talattof, Gordon L Amidon, Mirko Koziolek, Werner Weitschies, Clive G Wilson, Roelof J Bennink, Joachim Brouwers, Patrick Augustijns
Various gastrointestinal (GI) factors affect drug and formulation behavior after oral administration, including GI transfer, motility, pH and GI fluid volume and composition. An in-depth understanding of these physiological and anatomical variables is critical for a continued progress in oral drug development. In this review, different methodologies (invasive versus non-invasive) to explore the impact of physiological variables on formulation behavior in the human GI tract are presented, revealing their strengths and limitations...
November 30, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27909769/evaluation-of-131-i-scintigraphy-and-stimulated-thyroglobulin-levels-in-the-follow-up-of-patients-with-dtc-a-retrospective-analysis-of-1420-patients
#7
Jose Manuel Gonzalez Carvalho, Dennis Görlich, Otmar Schober, Christian Wenning, Burkhard Riemann, Frederik Anton Verburg, Alexis Vrachimis
AIM: To study the clinical yield of diagnostic whole body (131)I scintigraphy (DxWBS) in the follow-up of differentiated thyroid carcinoma (DTC) patients in relation to stimulated thyroglobulin (sTg) in the initial post-ablation setting, as well as in the setting of repeated monitoring in course of further DTC follow-up. METHODS: Data of 1420 thyroidectomized and radioiodine remnant-ablated DTC patients following a well-defined therapy and standardized follow-up protocol were evaluated...
December 1, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27904855/multiple-endocrine-neoplasia-type-1-with-anterior-mediastinal-parathyroid-adenoma-successful-localization-using-tc-99m-sestamibi-spect-ct
#8
Hye Lim Park, Ie Ryung Yoo, Sung Hoon Kim, Sohee Lee
The most common manifestation of multiple endocrine neoplasia type 1 (MEN1) is hyperparathyroidism. Treatment of hyperparathyroidism in MEN patients is surgical removal of the parathyroid glands, however ectopic parathyroid gland is challenging for treatment. A 51-year-old female, the eldest of 3 MEN1 sisters, had hyperparathyroidism with ectopic parathyroid adenoma in the mediastinal para-aortic region, which was detected by technetium-99m (Tc-99m) sestamibi scintigraphy and single-photon emission computed tomography/computed tomography (SPECT/CT)...
December 2016: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/27904246/noninvasive-imaging-of-the-biliary-system-relevant-to-percutaneous-interventions
#9
REVIEW
Stephen Thomas, Kayleen Jahangir
Clinical data such as history, physical examination, and laboratory tests are useful in identifying patients with biliary obstruction and biliary sources of infection. However, if intervention is planned, noninvasive imaging is needed to confirm the presence, location, and extent of the disease process. Currently, the most commonly available and used noninvasive modalities are ultrasound (US), computed tomography (CT), magnetic resonance (MR), and nuclear medicine hepatobiliary scintigraphy (HIDA). US is quick, portable, readily available, and is commonly the first imaging modality used when biliary pathology is suspected...
December 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27900958/renal-shear-wave-velocity-and-estimated-glomerular-filtration-rate-in-children-with-chronic-kidney-disease
#10
Costanza Bruno, Milena Brugnara, Rocco Micciolo, Mariangela Cecchetto, Michele Zuffante, Alessandra Bucci, Marco Zaffanello
A shear wave velocity (SWV) value obtained by the acoustic radiation force impulse technique depends on tissue elasticity. We investigated the relationship between SWV values and the estimated glomerular filtration rate (eGFR) in children with chronic kidney disease. A total of 29 patients were enrolled in the study. There were 18 primary and 11 secondary cases of vesicoureteral reflux. eGFR was calculated using Schwartz's formulas (2012). Partial eGFR for each kidney was assessed by multiplying the eGFR by the percentage of renal function measured by means of renal (99m)Tc-dimercaptosuccinic acid scintigraphy...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27900863/-symptomatic-and-asymptomatic-primary-hyperparathyroidism-in-outpatient-care-current-issues
#11
Helena Šiprová, Miroslav Souček, Zdeněk Fryšák, Květoslav Šipr
OBJECTIVE: To assess the diagnostic and therapeutic options in the care of patients with primary hyperparathyreosis in outpatient practice.Cohort and methods: The study included all the patients with primary hyperparathyroidism treated at the 2nd Internal Medicine Department, Masaryk University and the University Hospital of St. Anne in Brno in the period from Jan 1, 2008 to Dec 31, 2013. The sample consisted of 218 patients, including 41 men and 177 women. Patients with secondary hyperparathyroidism, especially patients with underlying hypovitaminosis D, renal insufficiency and those taking medications with possible effects on parathyroid hormone levels, have not been included in the study...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27900759/torsion-of-the-undescended-testis-detected-by-99mtc-testicular-scintigraphy-a-case-report
#12
Hamed Shayegani, Ghasemali Divband, Mahmoud Tavakkoli, Maliheh Banihasan, Ramin Sadeghi
We reported a case of torsion of the undescended testis in a 9-month-old boy which was diagnosed with 99mTc testicular scin-tigraphy. The scan showed diffuse increased activity in the location of the undescended testis and no photopenic area was visible. At surgery, torsion of the undescended testis was detected and fixed.
2016: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/27900474/bone-scan-usefulness-in-patients-with-painful-hip-or-knee-prosthesis-10-situations-that-can-cause-pain-other-than-loosening-and-infection
#13
REVIEW
Sofia Vaz, Teresa C Ferreira, Lucília Salgado, Frédéric Paycha
In recent years, with the higher median life expectancy, the number of hip and knee replacements has increased. Clinical examination and morphological studies are essential to evaluate patients with a painful arthroplasty. Nuclear medicine examinations also play an important role, their main usefulness being the exclusion of prosthesis complications. Nevertheless, conventional examinations, namely bone scan and white blood cell scintigraphy, can also identify complications, such as loosening and infection. This study describes the normal and pathologic patterns of a bone scan and exemplifies ten common situations that can cause pain in patients with hip or knee arthroplasty, other than loosening and infection, which can be disclosed on a bone scintigraphy...
November 30, 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27900219/outcome-of-laparoscopic-upper-pole-heminephroureterectomy-in-children-a-two-centre-experience
#14
Ali Serdar Gözen, Haytham Badawy, Dogu Teber, Akram Assem, Jens Rassweiler
OBJECTIVE: To report our multicentre experience and outcomes with laparoscopic transperitoneal and retroperitoneal upper pole heminephroureterectomy (HNU) in children with renal duplex systems and impaired upper pole. PATIENTS AND METHODS: Laparoscopic HNU was performed in 22 children (15 girls, seven boys) with a mean age of 5.9 years. A retroperitoneal approach was used in 17 patients and a transperitoneal approach in the remaining five, between 2005 and 2010...
December 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/27898646/iodine-123-metaiodobenzylguanidine-scintigraphy-for-the-assessment-of-cardiac-sympathetic-innervation-and-the-relationship-with-cardiac-autonomic-function-in-healthy-adults-using-standardized-methods
#15
Omar Asghar, Parthiban Arumugam, Ian Armstrong, Simon Ray, Matthias Schmitt, Rayaz A Malik
BACKGROUND: Global iodine-123 metaiodobenzylguanidine (I-MIBG) uptake is predictive of cardiovascular events and mortality in patients with heart failure. Normal variations in global and regional uptake, however, are not well defined and few studies have addressed the functional relevance of I-MIBG uptake and distribution in healthy individuals. MATERIALS AND METHODS: We performed I-MIBG scintigraphy and cardiac autonomic function testing using the standardized methodology in 15 healthy individuals (mean age 54...
January 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27897064/diagnosis-of-dementia-with-lewy-bodies-can-123-i-imp-and-123-i-mibg-scintigraphy-yield-new-core-features
#16
Fumi Sakamoto, Shinya Shiraishi, Noriko Tsuda, Mamoru Hashimoto, Seiji Tomiguchi, Manabu Ikeda, Yasuyuki Yamashita
OBJECTIVE: Since the clinical symptoms of different types of dementia frequently overlap, especially in the earlier stages at onset, it is difficult to distinguish dementias with Lewy bodies (DLB) from other neurodegenerative dementias based on their clinical manifestations alone. Nuclear medicine imaging has been reported as a high-value index for the objective evaluation and diagnosis of DLB. The aim of this study was to evaluate whether nuclear medicine imaging findings may yield core features to be added to the diagnosis of DLB...
November 29, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27890881/non-convulsive-status-epilepticus-with-takotsubo-cardiomyopathy-a-case-report
#17
Jyunichi Uemura, Yuko Wada, Yoshiki Yagita
A 61-year-old woman was admitted to our hospital for speech disturbance and mild consciousness impairment. Despite the absence of seizures or loss of consciousness, electroencephalographic abnormalities were observed, and the cerebral blood flow scintigraphy revealed an increase in cerebral blood flow in the left temporal lobe. These findings suggested a diagnosis of non-convulsive status epilepticus. On the third day, a twelve-lead electrocardiogram showed a negative T-wave in I, II, aVf, and V2-6. Moreover, a transthoracic echocardiogram revealed left ventricular apical akinesis...
November 25, 2016: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/27889527/-177-lu-dotatate-treatment-in-neuroendocrine-tumours-a-preliminary-study
#18
I Hervás, P Bello, M Falgas, M I Del Olmo, I Torres, C Olivas, V Vera, P Oliván, A M Yepes
Therapy with radiolabelled somatostatin analogue peptides is a promising new therapy to treat neuroendocrine tumours. The aim of this preliminary study is to present our experience with (177)Lu-DOTATATE therapy, and evaluate tolerability and short-term efficacy in patients with tumours expressing somatostatin receptors. A total of 7 patients with metastatic neuroendocrine tumours were treated, each with 4 doses of (177)Lu-DOTATATE. The treatment response was evaluated in the form of biochemical response (tumour markers), imaging methods (somatostatin receptor scintigraphy, computed tomography, and magnetic resonance), and functional and quality of life responses using the Karnofsky performance status scale...
November 23, 2016: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/27889221/the-swedish-infant-high-grade-reflux-trial-study-presentation-and-vesicoureteral-reflux-outcome
#19
Josefin Nordenström, Gundela Holmdahl, Per Brandström, Rune Sixt, Eira Stokland, Ulla Sillén, Sofia Sjöström
INTRODUCTION: High-grade vesicoureteral reflux (VUR) in infants is associated with congenital renal abnormalities, recurrent UTI, and bladder dysfunction. Endoscopic treatment (ET) is a well-established method in children with low to moderate reflux grades, but there is a lack of randomised controlled trials regarding the use of ET versus continuous antibiotic prophylaxis in infants with high-grade VUR. OBJECTIVE: This study aimed to determine whether high-grade VUR in infants can be treated with endoscopic injection and whether ET is superior to antibiotic prophylaxis in the treatment of VUR...
October 24, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27889090/focal-nodular-and-diffuse-haematopoietic-marrow-hyperplasia-in-patients-with-underlying-malignancies-a-radiological-mimic-of-malignancy-in-need-of-recognition
#20
L T C Chow, A W H Ng, S K C Wong
AIM: To report the authors' experience of focal nodular haematopoietic marrow hyperplasia (FNHMH) and diffuse haematopoietic marrow hyperplasia (DHMH) clinically masquerading as skip, distant, or disseminated metastasis in seven patients with underlying malignant neoplasms. MATERIALS AND METHODS: Five patients with FNHMH and two with DHMH mistaken radiologically as skip and disseminated metastasis, respectively, were compared and contrasted with four patients with osteosarcomas and two with chondrosarcomas harbouring skip metastasis, noting the temporal relationship with their haematological profile...
November 24, 2016: Clinical Radiology
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