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https://www.readbyqxmd.com/read/29148096/performance-of-the-dimension-tac-assay-and-comparison-of-multiple-platforms-for-the-measurement-of-tacrolimus
#1
Eun-Jung Cho, Dae-Hyun Ko, Woochang Lee, Sail Chun, Hae-Kyung Lee, Won-Ki Min
BACKGROUND: Therapeutic monitoring of tacrolimus is essential for reducing organ rejection and adverse effects. The measurement of tacrolimus in whole blood is taken by many automated platforms. We evaluated the analytical performance of the Dimension TAC assay, which is an upgraded reagent from the previous Dimension TACR assay. METHODS: The evaluations involved determination of precision, linearity, detection capability, and reagent lot-to-lot variability between three lot numbers...
November 17, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29142283/a-mobile-device-based-imaging-spectrometer-for-environmental-monitoring-by-attaching-a-lightweight-small-module-to-a-commercial-digital-camera
#2
Fuhong Cai, Wen Lu, Wuxiong Shi, Sailing He
Spatially-explicit data are essential for remote sensing of ecological phenomena. Lately, recent innovations in mobile device platforms have led to an upsurge in on-site rapid detection. For instance, CMOS chips in smart phones and digital cameras serve as excellent sensors for scientific research. In this paper, a mobile device-based imaging spectrometer module (weighing about 99 g) is developed and equipped on a Single Lens Reflex camera. Utilizing this lightweight module, as well as commonly used photographic equipment, we demonstrate its utility through a series of on-site multispectral imaging, including ocean (or lake) water-color sensing and plant reflectance measurement...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29116859/what-about-the-trees-trees-as-nature-based-shade-sails
#3
Robert Zarr, Tamberly Conway
No abstract text is available yet for this article.
December 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29115683/role-of-chemokines-and-the-corresponding-receptors-in-vitiligo-a-pilot-study
#4
Lingling Yang, Sailing Yang, Jiehao Lei, Wenting Hu, Rong Chen, Fuquan Lin, Ai-E Xu
To determine the levels and sources of chemokines in the serum and epidermis of vitiligo patients, we examined 80 active patients, 80 stable patients and 40 healthy controls. First, the serum levels of candidate chemokines were measured by Luminex assay, and levels of CCR5, CXCR1 and CXCR3 were measured in peripheral mononuclear cells (PMBC) by flow cytometry. Then, the local epidermis levels of elevated chemokines in vitiligo were tested by Luminex. Finally, the mRNA and protein expression levels of elevated chemokines in HaCaT cells stimulated with interferon (IFN)-γ or tumor necrosis factor (TNF)-α were tested by quantitative real-time polymerase chain reaction and Luminex...
November 8, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/29113907/assessing-the-prevalence-of-protein-energy-wasting-in-haemodialysis-patients-a-cross-sectional-monocentric-study
#5
Rajaa Essadik, Rajaa Msaad, Halima Lebrazi, Hassan Taki, El Hassane Tahri, Anass Kettani, Ghizlane Madkouri, Benyounes Ramdani, Rachid Saïle
INTRODUCTION: Protein-energy wasting (PEW) is a strong predictive factor for morbidity and mortality in haemodialysis (HD) patients. However, there is no consensus for its assessment. The present study aimed to assess the nutritional status of patients on chronic HD by use of different nutritional assessment parameters, and at verifying which can identify the greatest number of HD patients with PEW. Also, to investigate predictors of nutritional status in a haemodialysis center in Morocco...
November 4, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29105935/silique-valves-as-sails-in-anemochory-of-lunaria-brassicaceae
#6
Peter Leins, Kerstin Fligge, Claudia Erbar
The generally held opinion that the seeds of Lunaria remain at the replum after detachment of the two valves and then the wind causes a shaking or rattling of the replum with its diaphragm, thus launching the seeds was challenged by the first author. In a sparse forest in the Swabian Alb, he noticed flying valves of Lunaria rediviva to which the narrow-winged flat seeds are attached. Investigations by SEM and histology have shown that the valves secrete a glue just at those sites where the seeds rest on the valves before the dying of the valvar tissues...
November 4, 2017: Plant Biology
https://www.readbyqxmd.com/read/29094175/spinnaker-sail-sign
#7
REVIEW
Venkatraman Indiran, Kanakaraj Kannan, T Ramachandra Prasad, Prabakaran Maduraimuthu
No abstract text is available yet for this article.
November 1, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29079556/the-disvalue-of-death-in-the-global-burden-of-disease
#8
Carl Tollef Solberg, Ole Frithjof Norheim, Mathias Barra
In the Global Burden of Disease study, disease burden is measured as disability-adjusted life years (DALYs). The paramount assumption of the DALY is that it makes sense to aggregate years lived with disability (YLDs) and years of life lost (YLLs). However, this is not smooth sailing. Whereas morbidity (YLD) is something that happens to an individual, loss of life itself (YLL) occurs when that individual's life has ended. YLLs quantify something that involves no experience and does not take place among living individuals...
October 27, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/29075223/brain-functional-plasticity-driven-by-career-experience-a-resting-state-fmri-study-of-the-seafarer
#9
Nizhuan Wang, Weiming Zeng, Yuhu Shi, Hongjie Yan
The functional connectome derived from BOLD resting-state functional magnetic resonance imaging data represents meaningful functional organizations and a shift between distinct cognitive states. However, the body of knowledge on how the long-term career experience affects the brain's functional plasticity is still very limited. In this study, we used a dynamic functional connectome characterization (DBFCC) model with the automatic target generation process K-Means clustering to explore the functional reorganization property of resting brain states, driven by long-term career experience...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29069310/morca-sailing-bioinformatics-world-with-mobile-devices
#10
Sergio Díaz-Del-Pino, Juan Falgueras, Esteban Perez-Wohlfeil, Oswaldo Trelles
Motivation: Nearly ten years have passed since the first mobile apps appeared. Given the fact that bioinformatics is a web-based world and that mobile devices are endowed with web-browsers, it seemed natural that bioinformatics would transit from personal computers to mobile devices but nothing could be further from the truth. The transition demands new paradigms, designs and novel implementations. Results: Throughout an in-depth analysis of requirements of existing bioinformatics applications we designed and deployed an easy-to-use web-based lightweight mobile client...
October 24, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29059611/validating-epilepsy-diagnoses-in-routinely-collected-data
#11
Beata Fonferko-Shadrach, Arron S Lacey, Catharine P White, H W Rob Powell, Inder M S Sawhney, Ronan A Lyons, Phil E M Smith, Mike P Kerr, Mark I Rees, W Owen Pickrell
PURPOSE: Anonymised, routinely-collected healthcare data is increasingly being used for epilepsy research. We validated algorithms using general practitioner (GP) primary healthcare records to identify people with epilepsy from anonymised healthcare data within the Secure Anonymised Information Linkage (SAIL) databank in Wales, UK. METHOD: A reference population of 150 people with definite epilepsy and 150 people without epilepsy was ascertained from hospital records and linked to records contained within SAIL (containing GP records for 2...
October 13, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29051497/achieving-high-efficiency-emission-depletion-nanoscopy-by-employing-cross-relaxation-in-upconversion-nanoparticles
#12
Qiuqiang Zhan, Haichun Liu, Baoju Wang, Qiusheng Wu, Rui Pu, Chao Zhou, Bingru Huang, Xingyun Peng, Hans Ågren, Sailing He
Stimulated emission depletion microscopy provides a powerful sub-diffraction imaging modality for life science studies. Conventionally, stimulated emission depletion requires a relatively high light intensity to obtain an adequate depletion efficiency through only light-matter interaction. Here we show efficient emission depletion for a class of lanthanide-doped upconversion nanoparticles with the assistance of interionic cross relaxation, which significantly lowers the laser intensity requirements of optical depletion...
October 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/29048958/shade-sails-and-passive-recreation-in-public-parks-of-melbourne-and-denver-a-randomized-intervention
#13
RANDOMIZED CONTROLLED TRIAL
David B Buller, Dallas R English, Mary Klein Buller, Jody Simmons, James A Chamberlain, Melanie Wakefield, Suzanne Dobbinson
OBJECTIVES: To test whether shade sails will increase the use of passive recreation areas (PRAs). METHODS: We conducted a stratified randomized pretest-posttest controlled design study in Melbourne, Australia, and Denver, Colorado, in 2010 to 2014. We randomized a sample of 144 public parks with 2 PRAs in full sun in a 1:3 ratio to treatment or control. Shade sails were built at 1 PRA per treatment park. The outcome was any use of the study PRA (n = 576 pretest and n = 576 posttest observations; 100% follow-up)...
December 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29048249/effect-of-teaching-races-for-understanding-in-youth-sailing-on-performance-knowledge-and-adherence
#14
María Trinidad Morales-Belando, José L Arias-Estero
PURPOSE: The purpose of this study was to know whether an intervention using an adaptation of the teaching games for understanding approach (named teaching races for understanding [TRfU]) led participants to improve skill execution, decision making, race performance, race involvement, race knowledge, enjoyment, intention to continue practicing sailing, and perceived competence. METHOD: Participants were 67 children from a randomly selected sailing school (Mage = 9...
October 19, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29041218/oil-pollution-discrimination-by-an-inelastic-hyperspectral-scheimpflug-lidar-system
#15
Fei Gao, Jingwei Li, Hongze Lin, Sailing He
An inelastic hyperspectral Scheimpflug lidar system is developed for range-resolved oil pollution detection and discrimination. A theory of system parametric design is built for aquatic circumstances, and laser-induced fluorescence spectra with an excitation wavelength of 446 nm are employed to detect oil pollution. Seven kinds of typical oil samples are tested and well distinguished using the principal component analysis (PCA) and linear discriminant analysis (LDA) methods. It has been shown that blue laser diodes (LD) have great potential for oil pollution detection, and our system could be further utilized for more applications in both marine and terrestrial environments...
October 16, 2017: Optics Express
https://www.readbyqxmd.com/read/29035599/progressive-dehydration-in-junior-laser-class-sailors-during-world-championship
#16
Giannis Arnaoutis, Panagiotis Verginadis, Adam D Seal, Ioannis Vogiatzis, Labros S Sidossis, Stavros A Kavouras
The purpose of this manuscript is to assess hydration status of elite young sailing athletes during World Championship competition. 12 young elite male Laser Class sailors (age: 15.8±1.1 y, height: 1.74±0.1 m, weight: 65.1±1.5 kg, body fat: 12.5±3.1%, training experience: 7.0±1.2 y) participated in this descriptive study. After three-day baseline bodyweight measurements, hydration status was assessed via pre- and post-race body weights, urine specific gravity, and thirst ratings via a visual analog scale during 4 consecutive days of racing...
October 16, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29031154/thermally-stable-microemulsions-comprising-imidazolium-based-surface-active-ionic-liquids-non-polar-ionic-liquid-and-ethylene-glycol-as-polar-phase
#17
Manvir Kaur, Gurbir Singh, Sandeep Kumar, Navnidhi, Tejwant Singh Kang
Ionic liquid (IL), 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide, [C2mim] [Tf2N], as a non-polar phase in conjunction with polar ethylene glycol (EG) forms microemulsions stabilized by surface active ionic liquids (SAILs), N-methyl-N-alkylimidazolium chlorides, [Cnmim] [Cl], where n = 8, 12 and 16 in conjunction with decanol as co-surfactant. The phase behaviour of the ternary systems has been investigated and three regions of microemulsions - polar-in-ionic liquid, bicontinuous and ionic liquid-in-polar, have been identified using electrical conductivity measurements...
October 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29027266/reliable-and-sensitive-physical-testing-of-elite-trapeze-sailors
#18
Jonathan Bay, Jens Bojsen-Møller, Nikolai B Nordsborg
It was investigated, if a newly developed discipline specific test for elite-level trapeze sailors is reli-able and sensitive. Furthermore, the physical demands of trapeze sailing were examined. In part 1, nine national team athletes were accustomed to a simulated sailing test, which subsequently was completed on four occasions to determine test reliability and sensitivity to manipulations in body-weight. Rope-pulling mean power output (MPO), oxygen consumption (VO2 ), heart rate (HR) and blood lactate values were acquired in all trials...
October 13, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28989528/outbreak-column-20-are-outbreaks-man-made-disasters-that-display-intertwined-errors-of-human-judgement-and-behaviour
#19
Evonne T Curran
Man-made disasters are reported to have five intertwined errors of human judgement and behaviour. As outbreaks are essentially man-made disasters, the cited intertwined errors of engineering overreach, smooth sailing fallacy, insider view, risk-seeking incentives and social-herding were looked for in five notable outbreaks of Clostridium difficile infection. Engineering overreach was found to be the most identifiable error. The purpose of this reflective exercise was to turn hindsight into foresight and determine the intertwined levels of safety behaviour needed to prevent any future pathogen emerging to produce healthcare disasters...
July 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/28978747/optimal-dynamic-soaring-consists-of-successive-shallow-arcs
#20
Gabriel D Bousquet, Michael S Triantafyllou, Jean-Jacques E Slotine
Albatrosses can travel a thousand kilometres daily over the oceans. They extract their propulsive energy from horizontal wind shears with a flight strategy called dynamic soaring. While thermal soaring, exploited by birds of prey and sports gliders, consists of simply remaining in updrafts, extracting energy from horizontal winds necessitates redistributing momentum across the wind shear layer, by means of an intricate and dynamic flight manoeuvre. Dynamic soaring has been described as a sequence of half-turns connecting upwind climbs and downwind dives through the surface shear layer...
October 2017: Journal of the Royal Society, Interface
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