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Paediatric obesity

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https://www.readbyqxmd.com/read/28073908/the-neuroendocrine-sequelae-of-paediatric-craniopharyngioma-a-40-year-meta-data-analysis-of-185-cases-from-three-uk-centres
#1
Timothy Shao Ern Tan, Leena Patel, Jaya Sujatha Gopal-Kothandapani, Sarah Ehtisham, Esieza Clare Ikazoboh, Richard Hayward, Kristian Aquilina, Mars Skae, Nicky Thorp, Barry Pizer, Mohammed Didi, Conor Mallucci, Joanne C Blair, Mark N Gaze, Ian Kamaly-Asl, Helen Spoudeas, Peter E Clayton
Objectives The management of paediatric craniopharyngiomas was traditionally complete resection (CR), with better reported tumour control compared to partial resection (PR) or limited surgery (LS). The subsequent shift towards hypothalamic-sparing, conservative surgery with adjuvant radiotherapy (RT) to any residual tumour, aimed at reducing neuroendocrine morbidity, has not been systematically studied. Hence, we reviewed the sequelae of differing management strategies in paediatric craniopharyngioma across three UK tertiary centres over four decades...
January 10, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28065736/long-term-outcomes-of-bariatric-surgery-in-adolescents-with-severe-obesity-fabs-5-a-prospective-follow-up-analysis
#2
Thomas H Inge, Todd M Jenkins, Stavra A Xanthakos, John B Dixon, Stephen R Daniels, Meg H Zeller, Michael A Helmrath
BACKGROUND: Little is known about the long-term outcomes of bariatric surgery for severe adolescent obesity, raising questions about the durability of early responses to surgery. We aimed to analyse long-term (>5 years) outcomes of Roux-en-Y gastric bypass in a cohort of young adults who had undergone the operation during adolescence, in the Follow-up of Adolescent Bariatric Surgery at 5 Plus Years (FABS-5+) extension study. METHODS: A cohort of young people aged 13-21 years underwent Roux-en-Y gastric bypass for clinically severe obesity at a paediatric academic medical centre in the USA...
January 5, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28065734/laparoscopic-roux-en-y-gastric-bypass-in-adolescents-with-severe-obesity-amos-a-prospective-5-year-swedish-nationwide-study
#3
Torsten Olbers, Andrew J Beamish, Eva Gronowitz, Carl-Erik Flodmark, Jovanna Dahlgren, Gustaf Bruze, Kerstin Ekbom, Peter Friberg, Gunnar Göthberg, Kajsa Järvholm, Jan Karlsson, Staffan Mårild, Martin Neovius, Markku Peltonen, Claude Marcus
BACKGROUND: Severe obesity in adolescence is associated with reduced life expectancy and impaired quality of life. Long-term benefits of conservative treatments in adolescents are known to be modest, whereas short-term outcomes of adolescent bariatric surgery are promising. We aimed to compare 5-year outcomes of adolescent surgical patients after Roux-en-Y gastric bypass with those of conservatively treated adolescents and of adults undergoing Roux-en-Y gastric bypass, in the Adolescent Morbid Obesity Surgery (AMOS) study...
January 5, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28040759/novel-application-of-a-percutaneous-left-ventricular-assist-device-as-a-bridge-to-transplant-in-a-paediatric-patient-with-severe-heart-failure-due-to-viral-myocarditis
#4
Paul Perry, Elizabeth David, Broadus Atkins, Gary Raff
A 13-year obese female with suspected viral myocarditis presented with acute decompensated heart failure. Due to her body habitus, she was a poor candidate for immediate heart transplantation. A peripherally inserted left ventricular assist device (LVAD) was implanted via the right axillary artery. Following device insertion the patient experienced rapid improvement in symptoms. The LVAD provided effective left ventricular unloading for 50 days, promoting myocardial recovery and maintaining excellent patient performance status...
December 31, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28026862/evaluation-of-the-accuracy-of-common-weight-estimation-formulae-in-a-zambian-paediatric-surgical-population
#5
L Bowen, M Zyambo, D Snell, J Kinnear, M D Bould
Limited resources and access to healthcare in sub-Saharan Africa are associated with high rates of malnourished children, although many countries globally are demonstrating increasing childhood obesity. This study evaluated how well current age- or height-based formulae estimate the weight of children undergoing surgery in Zambia. All children under 14 years of age presenting for elective surgery at the University Teaching Hospital, Lusaka, had both height and weight measured. Their actual weight was compared against estimated weight from various formulae...
December 27, 2016: Anaesthesia
https://www.readbyqxmd.com/read/27986760/concurrent-aerobic-plus-resistance-exercise-versus-aerobic-exercise-alone-to-improve-health-outcomes-in-paediatric-obesity-a-systematic-review-and-meta-analysis
#6
Antonio García-Hermoso, Robinson Ramírez-Vélez, Rodrigo Ramírez-Campillo, Mark D Peterson, Vicente Martínez-Vizcaíno
OBJECTIVE: To determine if the combination of aerobic and resistance exercise is superior to aerobic exercise alone for the health of obese children and adolescents. DESIGN: Systematic review with meta-analysis. DATA SOURCES: Computerised search of 3 databases (MEDLINE, EMBASE, and Cochrane Controlled Trials Registry). ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Studies that compared the effect of supervised concurrent exercise versus aerobic exercise interventions, with anthropometric and metabolic outcomes in paediatric obesity (6-18 years old)...
December 16, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27900849/combined-use-of-a-wristband-and-a-smartphone-to-reduce-body-weight-in-obese-children-randomized-controlled-trial
#7
C Mameli, D Brunetti, V Colombo, G Bedogni, L Schneider, F Penagini, B Borsani, G V Zuccotti
BACKGROUND: Technological instruments may help control paediatric obesity. OBJECTIVE: We tested whether a personalized programme based on the energy expenditure obtained from a wristband (WB) and the energy intake obtained from a smartphone application (APP) is superior to a standard approach at promoting weight loss. METHODS: We performed a randomized controlled trial in obese children aged 10-17 years. The experimental (EXP) and control (CTR) groups were given a low-energy diet and a prescription for physical activity...
November 29, 2016: Pediatric Obesity
https://www.readbyqxmd.com/read/27889912/insulin-like-growth-factor-1-and-metabolic-parameters-are-associated-with-non-alcoholic-fatty-liver-disease-in-obese-children-and-adolescents
#8
Shuang Liang, Xiangdeng Cheng, Yanyan Hu, Ruxin Song, Guimei Li
AIM: Few studies have investigated the relationship between paediatric non-alcoholic fatty liver disease (NAFLD) and insulin like growth factor 1 (IGF-1). This study, carried out from July 2013 to September 2015, aimed to fill the gap and added metabolic parameters to the analysis. METHODS: This was a cross-sectional study of 168 obese children and adolescents (84% male), divided into two groups based on the presence (n=90) or absence (n=78) of NAFLD. All participants underwent clinical examinations, anthropometric and laboratory examinations and liver ultrasonography...
November 27, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27856476/development-and-psychometric-validation-of-the-parent-perspective-university-of-rhode-island-change-assessment-short-purica-s-questionnaire-for-the-application-in-parents-of-children-with-overweight-and-obesity
#9
Florian Junne, Katrin Ziser, Johannes Mander, Peter Martus, Christian Denzer, Thomas Reinehr, Martin Wabitsch, Susanna Wiegand, Tobias Renner, Katrin E Giel, Martin Teufel, Stephan Zipfel, Stefan Ehehalt
INTRODUCTION: High prevalence rates of childhood obesity urgently call for improved effectiveness of intervention programmes for affected children and their families. One promising attempt can be seen in tailoring interventions according to the motivational stages of parents as 'agents of change' for their children. Evidence from other behavioural contexts (eg, addiction) clearly shows the superiority of motivational-stage dependent tailored (behavioural) interventions. For the time-efficient assessment of motivational stages of change, this study aims to develop and psychometrically validate a 'Parent Perspective Version' of the existing University of Rhode Island Change Assessment-Short, an instrument assessing the motivational stages based on the theoretical fundamentals of the Transtheoretical Model of Psychotherapy...
November 17, 2016: BMJ Open
https://www.readbyqxmd.com/read/27803155/bridging-the-gap-metabolic-and-endocrine-care-of-patients-during-transition
#10
REVIEW
Anita Hokken-Koelega, Aart-Jan van der Lely, Berthold Hauffa, Gabriele Häusler, Gudmundur Johannsson, Mohamad Maghnie, Jesús Argente, Jean DeSchepper, Helena Gleeson, John W Gregory, Charlotte Höybye, Fahrettin Keleştimur, Anton Luger, Hermann L Müller, Sebastian Neggers, Vera Popovic-Brkic, Eleonora Porcu, Lars Sävendahl, Stephen Shalet, Bessie Spiliotis, Maithé Tauber
OBJECTIVE: Seamless transition of endocrine patients from the paediatric to adult setting is still suboptimal, especially in patients with complex disorders, i.e., small for gestational age, Turner or Prader-Willi syndromes; Childhood Cancer Survivors, and those with childhood-onset growth hormone deficiency. METHODS: An expert panel meeting comprised of European paediatric and adult endocrinologists was convened to explore the current gaps in managing the healthcare of patients with endocrine diseases during transition from paediatric to adult care settings...
November 2016: Endocrine Connections
https://www.readbyqxmd.com/read/27789201/why-do-parents-discontinue-health-services-for-managing-paediatric-obesity-a-multi-centre-qualitative-study
#11
Jasmine Dhaliwal, Arnaldo J Perez, Nicholas L Holt, Rebecca Gokiert, Jean-Pierre Chanoine, Katherine M Morrison, Laurent Legault, Arya M Sharma, Geoff D C Ball
OBJECTIVE: To explore parents' reasons for discontinuing tertiary-level care for paediatric weight management. METHODS: Participants were parents of 10-17year olds (body mass index [BMI] ≥85th percentile) who were referred for paediatric weight management. Parents were recruited from three Canadian sites (Vancouver, BC; Edmonton, AB; Hamilton, ON) and were eligible if their children attended at least one clinical appointment and subsequently discontinued care...
October 24, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27780309/incidental-inflammatory-adenoma-with-%C3%AE-catenin-activation-in-the-setting-of-paediatric-nash
#12
S Oliveira, A K Samba, A J Towbin, A Gupta, J I Geller, J D Nathan, R Kohli
: Hepatocellular adenomas (HCA) are benign tumours with potential for malignant transformation with no recommendations regarding management in the paediatric population. We report a case of an inflammatory adenoma with β-catenin activated pathway in an obese, paediatric patient with nonalcoholic steatohepatitis (NASH). CASE REPORT: An 11-year-old female presented with a microlobulated liver lesion measuring >5 cm in magnetic resonance imaging (MRI) with inflammatory adenoma with β-catenin activated pathology arising in a background of NASH, nonalcoholic fatty liver disease (NAFLD) activity score 5/8...
October 25, 2016: Pediatric Obesity
https://www.readbyqxmd.com/read/27780307/the-contribution-of-recently-identified-adult-bmi-risk-loci-to-paediatric-obesity-in-a-singaporean-chinese-childhood-dataset
#13
R Dorajoo, R T-H Ong, X Sim, L Wang, W Liu, E S Tai, J Liu, S-M Saw
INTRODUCTION: Recent genome-wide association studies have identified 103 adult obesity risk loci; however, it is unclear if these findings are relevant to East-Asian childhood body mass index (BMI) levels. METHODS AND RESULTS: We evaluated for paediatric obesity associations at these risk loci utilizing genome-wide data from Chinese childhood subjects in the Singapore Cohort study Of the Risk factors for Myopia study (N = 1006). A weighted gene-risk score of all adult obesity risk loci in the Singapore Cohort study Of the Risk factors for Myopia study showed strong associations with BMI at age 9 (p-value = 3...
October 25, 2016: Pediatric Obesity
https://www.readbyqxmd.com/read/27759894/excessive-homework-inadequate-sleep-physical-inactivity-and-screen-viewing-time-are-major-contributors-to-high-paediatric-obesity
#14
Hong Ren, Zhixiong Zhou, Wenxi Kevin Liu, Xiujiang Wang, Zenong Yin
AIM: This study examined the relationships between energy balance-related behaviours (EBRBs) outside school hours and obesity in Chinese primary school students. We also explored the influence of gender on those relationships. METHODS: The study sample was a cross-sectional cohort of 5032 Chinese children who were enrolled in grades 1-6 in primary schools in five Chinese cities and whose mean ages ranged from seven years and three months to 11.9 years. The children's parents completed a survey on their child's height, weight and EBRBs outside school hours...
January 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/27747864/relationship-between-body-mass-index-and-dental-caries-in-children-and-the-influence-of-socio-economic-status
#15
Santhosh Kumar, Jeroen Kroon, Ratilal Lalloo, Suhas Kulkarni, Newell W Johnson
OBJECTIVES: To determine the association of body mass index (BMI) with dental caries in Indian schoolchildren, and to analyse the influence of socio-economic status (SES). METHODS: The study population consisted of 11- to 14-year-old children from Medak District in Telangana State, India. The Indian Academy of Paediatrics 2015 growth charts were used to categorise children as underweight, overweight, normal or obese, based on their BMI. Data on the SES of the family were collected through questionnaires...
October 17, 2016: International Dental Journal
https://www.readbyqxmd.com/read/27733746/oxidative-stress-status-in-childhood-obesity-a-potential-risk-predictor
#16
Elif Kilic, Ömer Faruk Özer, Aybala Erek Toprak, Hayriye Erman, Emel Torun, Sıddıka Kesgin Ayhan, Hifa Gülru Caglar, Sahbettin Selek, Abdurrahim Kocyigit
BACKGROUND Childhood obesity characterized by excessive fat in the body is one of the most serious health problems worldwide due to the social, medical, and physiological complications. Obesity and associated diseases are triggering factors for oxidative stress and inflammation. The aim of this study was to explore the possible association between childhood obesity and inflammatory and oxidative status. MATERIAL AND METHODS Thirty-seven obese children and 37 healthy controls selected from among children admitted to BLIND University Paediatrics Department were included in the study...
October 13, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27730073/characteristics-of-children-and-adolescents-at-onset-of-type-2-diabetes-in-a-tertiary-hospital-in-bangladesh
#17
Bedowra Zabeen, Jebun Nahar, Samin Tayyeb, Fauzia Mohsin, Nazmun Nahar, Kishwar Azad
INTRODUCTION: Recent data show that the prevalence of diabetes among children and adolescents is increasing in some ethnic groups. The worldwide epidemic of childhood obesity has been accompanied by an increase in the incidence of type 2 diabetes (T2D) in youth. METHODS: The aim of this study was to describe the baseline characteristics of children and adolescents diagnosed ≤18 years who had features of T2D and presented at Changing Diabetes in Children, Paediatric Diabetes Clinic at Bangladesh Institute of Research and Rehabilitation of Diabetes, Endocrine, and Metabolic Disorders...
September 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27694487/association-of-neck-circumference-with-general-and-abdominal-obesity-in-children-and-adolescents-the-weight-disorders-survey-of-the-caspian-iv-study
#18
Roya Kelishadi, Shirin Djalalinia, Mohammad Esmaiel Motlagh, Ali Rahimi, Maryam Bahreynian, Tahereh Arefirad, Gelayol Ardalan, Saeid Safiri, Motahare Hasani, Hamid Asayesh, Morteza Mansourian, Mostafa Qorbani
OBJECTIVES: This study aimed to evaluate the association of neck circumference (NC) with obesity to determine the sex-specific and age-specific optimal cut-off points of this measure in association with obesity in a national sample of the Iranian paediatric population. METHODS: This survey on weight disorders was conducted among a national sample of Iranian children and adolescents, aged 6-18 years. Using the area under the curve (AUC) of the receiver operator characteristic curves, we evaluated the association of NC with general and abdominal obesity...
September 30, 2016: BMJ Open
https://www.readbyqxmd.com/read/27622231/type-2-diabetes-mellitus-in-children-and-adolescents
#19
Kung-Ting Kao, Matthew A Sabin
BACKGROUND: The incidence of type 2 diabetes mellitus (T2DM) in children and adolescents is increasing, mirroring the epidemic of paediatric obesity. Early-onset T2DM is associated with poor long-term outcomes. OBJECTIVE: In this article, we describe the growing problem of early-onset T2DM in Australia, explore the difference between early-onset and adult-onset T2DM, and review the management of T2DM in children and adolescents. DISCUSSION: T2DM is difficult to differentiate from the more common type 1 diabetes mellitus (T1DM) in the paediatric population...
June 2016: Australian Family Physician
https://www.readbyqxmd.com/read/27612933/reporting-of-treatment-fidelity-in-behavioural-paediatric-obesity-intervention-trials-a-systematic-review
#20
REVIEW
M M JaKa, J L Haapala, E S Trapl, A S Kunin-Batson, B A Olson-Bullis, W J Heerman, J M Berge, S M Moore, D Matheson, N E Sherwood
Behavioural interventions for paediatric obesity are promising, but detailed information on treatment fidelity (i.e. design, training, delivery, receipt and enactment) is needed to optimize the implementation of more effective interventions. Little is known about current practices for reporting treatment fidelity in paediatric obesity studies. This systematic review, in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, describes the methods used to report treatment fidelity in randomized controlled trials...
December 2016: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
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