Susan Panahi, Zohreh Yazdi, Mahboubeh Sanchouli, Fatemehsadat Sajadi, Fateme Motavasselian, Hedyeh Maghareh Abed, Zahra Beygi, Seyed Mohammad Gheibihayat
Efferocytosis is the physiological process of phagocytic clearance of apoptotic cells by both professional phagocytic cells, such as macrophages, and non-professional phagocytic cells, such as epithelial cells. This process is crucial for maintaining tissue homeostasis in normal physiology. Any defects in efferocytosis can lead to pathological consequences and result in inflammatory diseases. Extracellular vesicles (EVs), including exosomes, microvesicles (MVs), and apoptotic vesicles (ApoVs), play a crucial role in proper efferocytosis...
October 5, 2023: Mini Reviews in Medicinal Chemistry