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https://www.readbyqxmd.com/read/26607930/biliary-tract-cancers-seom-clinical-guidelines
#1
M Benavides, A Antón, J Gallego, M A Gómez, A Jiménez-Gordo, A La Casta, B Laquente, T Macarulla, J R Rodríguez-Mowbray, J Maurel
Biliary tract cancer (BTC) is an uncommon and highly fatal malignancy. It is composed of three main different entities; Gall bladder carcinoma (GBC), intrahepatic cholangiocarcinoma (iCC) and extrahepatic cholangiocarcinoma (eCC) sharing different genetic, risk factors and clinical presentation. Multidetector-row computed tomography (MDCT) and magnetic resonance cholangio-pancreatography (MRCP) are the more important diagnostic techniques. Surgery is the only potentially curative therapy but disease recurrence is frequent...
December 2015: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/26478679/geographical-distribution-of-the-incidence-of-gastric-cancer-in-bhutan
#2
Tashi Dendup, James M Richter, Yoshio Yamaoka, Kinley Wangchuk, Hoda M Malaty
AIM: To estimate the prevalence of gastric cancer (GC) in a cohort of patients diagnosed with GC and to compare it with patients diagnosed with all other types of gastro-intestinal (GI) cancer during the same period. METHODS: Between 2008 and 2013, five-year period, the medical records of all GI cancer patients who underwent medical care and confirm diagnosis of cancer were reviewed at the National Referral Hospital, Thimphu which is the only hospital in the country where surgical and cancer diagnosis can be made...
October 14, 2015: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26100989/multidetector-ct-patterns-of-peritoneal-involvement-in-patients-with-abdominopelvic-malignancies
#3
Belqees Yawar, Sadia Babar, Imaad-Ur-Rehman, Farah Sana, Faiza Javed, Mohammad Yousuf Chaudhary
OBJECTIVE: To determine the patterns of peritoneal involvement in patients with abdominopelvic malignancies. STUDY DESIGN: Retrospective observational study. PLACE AND DURATION OF STUDY: Shifa International Hospital, Islamabad, Pakistan, from May 2004 to May 2012. METHODOLOGY: Two hundred and three patients with histopathologically proven abdominopelvic malignancies with peritoneal involvement who underwent contrast-enhanced CT abdomen and pelvis were identified through electronic data base system and were included in this study after ethical committee approval...
June 2015: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/25884694/surgery-for-recurrent-biliary-carcinoma-results-for-27-recurrent-cases
#4
Takehiro Noji, Takahiro Tsuchikawa, Tomoko Mizota, Keisuke Okamura, Toru Nakamura, Eiji Tamoto, Toshiaki Shichinohe, Satoshi Hirano
BACKGROUND: Various chemotherapies have been used as best practice to treat recurrent biliary malignancies. Conversely, relatively few surgeries have been described for recurrent extrahepatic biliary carcinoma (RExBC), so whether surgery for RExBC is feasible has remained unclear. This retrospective study was conducted to evaluate the feasibility of surgery for RExBC. METHODS: From February 2000 to January 2014, a total of 27 patients, comprising 18 patients with extrahepatic cholangiocarcinoma and 9 patients with gallbladder carcinoma, met our criteria for radical resection of RExBC (resection group)...
2015: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/25687629/the-epidemiology-of-inflammatory-bowel-disease
#5
REVIEW
Johan Burisch, Pia Munkholm
BACKGROUND AND AIMS: The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), are chronic relapsing disorders of unknown aetiology. The aim of this review is to present the latest epidemiology data on occurrence, disease course, risk for surgery, as well as mortality and cancer risks. MATERIAL AND METHODS: Gold standard epidemiology data on the disease course and prognosis of patients with inflammatory bowel disease (IBD) are based on unselected population-based cohort studies...
August 2015: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/25605984/intraoperative-endoscopic-retrograde-cholangio-pancreatography-a-useful-tool-in-the-hands-of-the-hepatobiliary-surgeon
#6
Ayman El Nakeeb, Ahmad M Sultan, Emad Hamdy, Ehab El Hanafy, Ehab Atef, Tarek Salah, Ahmed A El Geidie, Tharwat Kandil, Mohamed El Shobari, Gamal El Ebidy
AIM: To evaluate the efficacy of intraoperative endoscopic retrograde cholangio-pancreatography (ERCP) combined with laparoscopic cholecystectomy (LC) for patients with gall bladder stones (GS) and common bile duct stones (CBDS). METHODS: Patients treated for GS with CBDS were included. LC and intraoperative transcystic cholangiogram (TCC) were performed in most of the cases. Intraoperative ERCP was done for cases with proven CBDS. RESULTS: Eighty patients who had GS with CBDS were included...
January 14, 2015: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/25132767/comparative-analysis-of-ercp-idus-eus-and-ct-in-predicting-malignant-bile-duct-strictures
#7
COMPARATIVE STUDY
Hauke S Heinzow, Sara Kammerer, Carina Rammes, Johannes Wessling, Dirk Domagk, Tobias Meister
AIM: To compare endoscopic retrograde cholangio-pancreatography (ERCP), intraductal ultrasound (IDUS), endosonography (EUS), endoscopic transpapillary forceps biopsies (ETP) and computed tomography (CT) with respect to diagnosing malignant bile duct strictures. METHODS: A patient cohort with bile duct strictures of unknown etiology was examined by ERCP and IDUS, ETP, EUS, and CT. The sensitivity, specificity, and accuracy rates of the diagnostic procedures were calculated based on the definite diagnoses proved by histopathology or long-term follow-up in those patients who did not undergo surgery...
August 14, 2014: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/24778075/preoperative-18f-fdg-pet-ct-maximum-standardized-uptake-value-predicts-recurrence-of-biliary-tract-cancer
#8
Min-Su Park, Sang-Mok Lee
(18)F-Fluorodeoxyglucose positron-emission with computed tomography ((18)F-FDG PET-CT) is an imaging technique based on the increased uptake of glucose characteristically seen in malignant lesions. The preoperative maximum standardized uptake value (SUVmax) of PET-CT has been identified as a powerful significant prognostic factor for predicting recurrence in malignant tumors. Therefore, the aim of this study was to determine whether (18)F-FDG PET-CT has a prognostic significance in patients with biliary tract cancer after surgical resection...
May 2014: Anticancer Research
https://www.readbyqxmd.com/read/24760694/-intraductal-papillary-mucinous-neoplasm-of-the-pancreas
#9
J Rosendahl, J Mössner
The diagnosis of cystic pancreatic lesions is raised more often within the last years. This is due to the fact that diagnostic opportunities and modalities such as endosonography (EUS), magnetic resonance imaging (MRI), magnetic resonance cholangio-pancreatography (MRCP), and computertomography (CT) have both improved and are more widely used. As such new recommendations were needed, since the knowledge on cystic pancreatic lesions has increased after the last consensus statement published in 2006.  In this review the main aspects of the recent consensus statements for diagnosis and therapy or in some cases the surveillance strategy of intraductal papillary mucinous neoplasm will be summarized...
May 2014: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/24442173/role-of-ultrasound-as-compared-with-ercp-in-patient-with-obstructive-jaundice
#10
COMPARATIVE STUDY
S Karki, K S Joshi, S Regmi, R B Gurung, B Malla
BACKGROUND: The diagnosis of obstructive jaundice relies on proper history taking, clinical examination, laboratory investigations and different non invasive imaging modalities like Ultrasonography (USG), Cholangio Computed Tomography (CCT), Magnetic resonance Imaging (MRI) with Magnetic Resonance Cholangio Pancreatography (MRCP) and invasive modalities like endoscopic retrograde cholangiography (ERCP) and percutaneous trans hepatic cholangiography (PTC). OBJECTIVE: To compare the role of ultrasound with endoscopic retrograde cholangiography and to determine the major causes of obstructive jaundice in our prospect...
July 2013: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/24393919/-insertion-of-percutaneous-transhepatic-biliary-endoprosthesis-for-unresectable-lower-cholangiocellular-carcinoma-following-cholangitis-due-to-endoscopic-biliary-plastic-stent-obstruction
#11
Mayumi Kondo, Eiko Okamoto, Kentaro Takagi, Atsushi Tamura, Takao Shibayama, Ryota Seki, Jun Takasaki, Hidetoshi Amagasa, Hirotaka Kamikozuru, Hideaki Ganno, Katsunori Ami, Akira Fukuda, Takeshi Nagahama, Masayuki Ando, Kuniyoshi Arai
The patient was an 87-year-old woman who was diagnosed with atrial fibrillation, which was treated with an anticoagulant, and with chronic kidney disease. The patient was diagnosed as having liver dysfunction and lower cholangiocellular carcinoma (cStage I) on ultrasonography and magnetic resonance cholangiopancreatography. Since it was impossible to perform curative resection owing to the patient's decreased cardiac and renal function, we performed palliative endoscopic retrograde biliary drainage (ERBD) with a plastic stent (PS), and the patient was discharged 11 days later...
November 2013: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/23539059/-intraductal-papillary-mucinous-neoplasm-and-recurrent-pancreatitis
#12
Eduardo Gálvez, Gustavo Gálvez, Aurelio Barboza, Eduardo Barboza, Juan Manuel Combe, Mario R Combe, Juan Combe, Javier Arias Stella C, Javier Arias Stella
Ohashi described for the first time the IPMN on 1982 as a pancreatic neoplasia with mucine cells forming papillae and producing dilatation of the main pancreatic duct or its branches. The IPMN represent the 1% of the pancreatic tumors and 5% of the cystic neoplasias. It is potentially malignant in a period of five years being more frequent in males between 60-70 and clinically these patients' presents as acute, recurrent or chronic pancreatitis, with an incidence of malignancy from 25% to 70%. CT scan and cholangio MRI allows the diagnosis, the variety, localization and possibility of determine malignancy...
January 2013: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/23430958/intraductal-ultrasound-substantiates-diagnostics-of-bile-duct-strictures-of-uncertain-etiology
#13
Tobias Meister, Hauke S Heinzow, Carina Woestmeyer, Philipp Lenz, Josef Menzel, Torsten Kucharzik, Wolfram Domschke, Dirk Domagk
AIM: To report the largest patient cohort study investigating the diagnostic yield of intraductal ultrasound (IDUS) in indeterminate strictures of the common bile duct. METHODS: A patient cohort with bile duct strictures of unknown etiology was examined by IDUS. Sensitivity, specificity and accuracy rates of IDUS were calculated relating to the definite diagnoses proved by histopathology or long-term follow-up in those patients who did not undergo surgery. Analysis of the endosonographic report allowed drawing conclusions with respect to the T and N staging in 147 patients...
February 14, 2013: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/23247463/-clinical-characteristics-and-diagnosis-and-treatment-of-malignant-tumor-of-the-duodenum
#14
Ning Chen, Tong Lin Zhang
OBJECTIVE: To analyze the clinical characteristics of the malignant tumor of the duodenum and to improve the diagnosis and treatment. METHODS: The clinical data of 100 cases with malignant tumor of the duodenum at Peking University Third Hospital from 1974 to 2010 were summarized retrospectively. According to the different location of the tumors,the cases were divided into two groups: papilla tumor group and non-papillary region tumor group.Then the clinical manifestations, treatment and prognosis in the two groups were separately statistically compared...
December 18, 2012: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/22497948/intraoperative-assessment-of-the-resectability-of-hilar-cholangiocarcinoma
#15
Yoshio Shirai, Jun Sakata, Toshifumi Wakai, Katsuyoshi Hatakeyama
Major hepatectomy combined with extrahepatic bile duct resection has gained acceptance as a standard radical procedure for hilar cholangiocarcinoma. Here, we describe an operative technique, "taping of the right hepatic artery behind Calot's triangle", for assessing the resectability of hilar lesions for which left-sided hepatectomy is planned. Briefly, after retracting the gall-bladder anteriorly, the lateral peritoneum of the hepatoduodenal ligament is incised longitudinally (3-4cm in length) behind Calot's triangle and just to the left of the fissure of Ganz...
November 2012: Hepato-gastroenterology
https://www.readbyqxmd.com/read/22064341/coexistent-ampullary-squamous-cell-carcinoma-with-adenocarcinoma-of-the-pancreatic-duct
#16
Gayatri S Pathak, Sanjay D Deshmukh, Prasanna A Yavalkar, Amrut V Ashturkar
Primary squamous cell carcinoma (SCC) of ampulla has seldom been reported. However, metastatic SCC to ampulla of Vater is well known. We report a case of primary SCC of ampulla of Vater coexistent with well-differentiated adenocarcinoma of the distal pancreatic duct. A 50-year-old female presented with evidence of obstructive jaundice. Endoscopic retrograde cholangio-pancreatography revealed bulging papilla with ulcero-infiltrative growth at the ampulla of Vater. An initial endoscopic biopsy of the ampullary mass showed a well-differentiated SCC...
November 2011: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/21870733/-classification-and-staging-systems-for-hilar-cholangio-carcinoma-klatskin-tumors-clinical-application-and-practical-relevance
#17
V Gavrilovici, F Grecu, V Seripcariu, Cr Dragomir
Hilar cholangiocarcinomas or Klatskin tumors have been classified in 1975 by French surgeons Henri Bismuth and Marvin B. Corlette and this remains largely used in clinical practice. The authors present the TNM classification and the changes introduced by the sixth and seventh edition of Union for International Cancer Control regarding the tumors of the proximal bile duct and describe Blumgart classification for tumors of this site. The usefulness of these systems is assessed considering the last six years experience of the service...
April 2011: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/21140449/serological-afp-golgi-protein-73-could-be-a-new-diagnostic-parameter-of-hepatic-diseases
#18
Liyuan Tian, Yu Wang, Dabin Xu, Junhao Gui, Xingwang Jia, Hongli Tong, Xinyu Wen, Zhennan Dong, Yaping Tian
We have investigated the changing rule of serum form of GP73 (sGP73) in different hepato-pathologic processes and identified the sGP73 role in inflammation, fibrosis and carcinogenesis since sGP73 has been regarded as a candidate tumor marker. Quantitative enzyme-linked immunosorbent assay detected sGP73 in 535 subjects with hepatocellular carcinoma (HCC), liver cirrhosis (LC), hepatitis, focal nodular hyperplasia (FNH), angioma, intra-hepatic cholangio-carcinoma (ICC) and metastatic cancer from adenocarcinomas (MC)...
October 15, 2011: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/21042916/implications-of-intestinal-metaplasia-of-the-gallbladder-in-children-with-pancreaticobiliary-maljunction
#19
Shigeru Ono, Shigehisa Fumino, Naomi Iwai
PURPOSE: Pancreaticobiliary maljunction (PBM) is associated with an increased frequency of gallbladder malignancy. Intestinal metaplasia is often observed in gallbladder disease and is a risk factor for gallbladder carcinoma in adults. The hyperplasia-dysplasia-carcinoma progression is one of the possible mechanisms involved in biliary carcinogenesis. In this study, we evaluate the gallbladders of children with PBM for intestinal metaplasia and other histological changes. METHODS: From January 1997 to July 2010, 45 children with PBM were treated at our institution...
March 2011: Pediatric Surgery International
https://www.readbyqxmd.com/read/20809019/intraductal-papillary-mucinous-tumors-of-the-pancreas
#20
REVIEW
Daniela Dumitrescu, Carmen Florina Popescu, A Săftoiu
Intraductal papillary mucinous tumors (IPMTs) are benign and malignant lesions that arise from the epithelial lining of main pancreatic duct and/or branch pancreatic ducts, with excessive mucin production (especially hyperplastic/adenomatous variety). Based on the degree of cytoarchitectural atypia on microscopic examination, IPMTs are classified as benign, borderline, carcinoma in situ and invasive tumors. Imaging examinations are very important to establish the diagnosis. Two or more tests are usually required...
2010: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
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